CN185226

BLAST of CN185226 vs. ExPASy Swiss-Prot
Match: WNK2_MOUSE (Serine/threonine-protein kinase WNK2 OS=Mus musculus GN=Wnk2 PE=2 SV=2)

HSP 1 Score: 140.969 bits (354), Expect = 5.610e-33
Identity = 72/167 (43.11%), Postives = 108/167 (64.67%), Query Frame = 3

Query:  183 DEAKAHIGYIETDPNGRYGLFEEVLGKGAMKTVYKAIDEVLGVEVAWNQVRLNELMRSPDDLQRLYSEVHLLSTLKHDSIIRFYTSWIDV--DQKTFNFITEMFTSGTLREYRKKYRRVDIRAIKSWARQILQGLVYLHSRDPPVIHRDLKCDNIFVHGHLGQVKIG 677
            D+ KA    + T  +GR+  F+  LG+G+ KTVYK +D    VEVAW +++  +L +   + QR   E  +L  L+H +I+RFY  W      ++    +TE+ TSGTL+ Y K+++ +  + ++SW RQIL+GL++LH+R PP+IHRDLKCDNIF+ G  G VKIG
Sbjct:  181 DDLKA----VATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKL--ERQRFKEEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIG 341          

BLAST of CN185226 vs. ExPASy Swiss-Prot
Match: WNK2_HUMAN (Serine/threonine-protein kinase WNK2 OS=Homo sapiens GN=WNK2 PE=1 SV=4)

HSP 1 Score: 140.969 bits (354), Expect = 5.610e-33
Identity = 72/167 (43.11%), Postives = 108/167 (64.67%), Query Frame = 3

Query:  183 DEAKAHIGYIETDPNGRYGLFEEVLGKGAMKTVYKAIDEVLGVEVAWNQVRLNELMRSPDDLQRLYSEVHLLSTLKHDSIIRFYTSWIDV--DQKTFNFITEMFTSGTLREYRKKYRRVDIRAIKSWARQILQGLVYLHSRDPPVIHRDLKCDNIFVHGHLGQVKIG 677
            D+ KA    + T  +GR+  F+  LG+G+ KTVYK +D    VEVAW +++  +L +   + QR   E  +L  L+H +I+RFY  W      ++    +TE+ TSGTL+ Y K+++ +  + ++SW RQIL+GL++LH+R PP+IHRDLKCDNIF+ G  G VKIG
Sbjct:  181 DDLKA----VATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKL--ERQRFKEEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIG 341          

BLAST of CN185226 vs. ExPASy Swiss-Prot
Match: NRBP_MOUSE (Nuclear receptor-binding protein OS=Mus musculus GN=Nrbp1 PE=1 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 6.434e-21
Identity = 60/174 (34.48%), Postives = 97/174 (55.75%), Query Frame = 3

Query:  183 DEAKAHIGYIETDPNGRYGLFEEVLGKG---AMKTVYKAIDEVLGVEVAWNQVRLNELMRSPDDLQRLYSEVHLLSTLKHDSIIRFYTSWIDVDQKTFN--FITEMFTSGTLREYRKK----YRRVDIRAIKSWARQILQGLVYLHSRDPPVIHRDLKCDNIFVHGHLGQVKIG 677
            +E++     +E  P GR+    E + +     + + Y A+D   GVEV WN+V+ +E        +++ +    L  L+H +I++F+  W DV +      FITE  +SG+L+++ KK    ++ ++ +A K W  QIL  L YLHS DPP+IH +L CD IF+  H G +KIG
Sbjct:   47 EESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADVKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQ-HNGLIKIG 219          

BLAST of CN185226 vs. ExPASy Swiss-Prot
Match: NRBP_PONAB (Nuclear receptor-binding protein OS=Pongo abelii GN=NRBP1 PE=2 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 8.403e-21
Identity = 59/174 (33.91%), Postives = 97/174 (55.75%), Query Frame = 3

Query:  183 DEAKAHIGYIETDPNGRYGLFEEVLGKG---AMKTVYKAIDEVLGVEVAWNQVRLNELMRSPDDLQRLYSEVHLLSTLKHDSIIRFYTSWIDVDQKTFN--FITEMFTSGTLREYRKK----YRRVDIRAIKSWARQILQGLVYLHSRDPPVIHRDLKCDNIFVHGHLGQVKIG 677
            +E++     +E  P GR+    E + +     + + Y A+D   GVEV WN+V+ +E        +++ +    L  L+H +I++F+  W D+ +      FITE  +SG+L+++ KK    ++ ++ +A K W  QIL  L YLHS DPP+IH +L CD IF+  H G +KIG
Sbjct:   47 EESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQ-HNGLIKIG 219          

BLAST of CN185226 vs. ExPASy Swiss-Prot
Match: NRBP_MACFA (Nuclear receptor-binding protein OS=Macaca fascicularis GN=NRBP1 PE=2 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 8.403e-21
Identity = 59/174 (33.91%), Postives = 97/174 (55.75%), Query Frame = 3

Query:  183 DEAKAHIGYIETDPNGRYGLFEEVLGKG---AMKTVYKAIDEVLGVEVAWNQVRLNELMRSPDDLQRLYSEVHLLSTLKHDSIIRFYTSWIDVDQKTFN--FITEMFTSGTLREYRKK----YRRVDIRAIKSWARQILQGLVYLHSRDPPVIHRDLKCDNIFVHGHLGQVKIG 677
            +E++     +E  P GR+    E + +     + + Y A+D   GVEV WN+V+ +E        +++ +    L  L+H +I++F+  W D+ +      FITE  +SG+L+++ KK    ++ ++ +A K W  QIL  L YLHS DPP+IH +L CD IF+  H G +KIG
Sbjct:   47 EESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQ-HNGLIKIG 219          

BLAST of CN185226 vs. ExPASy Swiss-Prot
Match: NRBP_HUMAN (Nuclear receptor-binding protein OS=Homo sapiens GN=NRBP1 PE=1 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 8.403e-21
Identity = 59/174 (33.91%), Postives = 97/174 (55.75%), Query Frame = 3

Query:  183 DEAKAHIGYIETDPNGRYGLFEEVLGKG---AMKTVYKAIDEVLGVEVAWNQVRLNELMRSPDDLQRLYSEVHLLSTLKHDSIIRFYTSWIDVDQKTFN--FITEMFTSGTLREYRKK----YRRVDIRAIKSWARQILQGLVYLHSRDPPVIHRDLKCDNIFVHGHLGQVKIG 677
            +E++     +E  P GR+    E + +     + + Y A+D   GVEV WN+V+ +E        +++ +    L  L+H +I++F+  W D+ +      FITE  +SG+L+++ KK    ++ ++ +A K W  QIL  L YLHS DPP+IH +L CD IF+  H G +KIG
Sbjct:   47 EESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQ-HNGLIKIG 219          

BLAST of CN185226 vs. ExPASy Swiss-Prot
Match: NRBP_DROME (Nuclear receptor-binding protein homolog OS=Drosophila melanogaster GN=Madm PE=1 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 5.447e-20
Identity = 59/177 (33.33%), Postives = 94/177 (53.11%), Query Frame = 3

Query:  177 AGDEAKAHIGYIETDPNGRYGLFEEVLGKG---AMKTVYKAIDEVLGVEVAWNQVRLNELMRSPDDLQRLYSEVHLLSTLKHDSIIRFYTSWIDVDQKT---FNFITEMFTSGTLREYRKKYRR----VDIRAIKSWARQILQGLVYLHSRDPPVIHRDLKCDNIFVHGHLGQVKIG 677
            +GD+++     +E  P GR+    E + +     +  V+ A+D   GVEV WN+V+   L       +++      L  L H +I++F+  W D  Q       FITE  +SG+L+++ K+ +R    + + + + W  QIL  L YLHS  PP+IH +L CD+IF+  H G VKIG
Sbjct:   86 SGDDSEDESEILEESPCGRWLKRREEVDQRDVPGIDCVHLAMDTEEGVEVVWNEVQYASLQELKSQEEKMRQVFDNLLQLDHQNIVKFHRYWTDTQQAERPRVVFITEYMSSGSLKQFLKRTKRNAKRLPLESWRRWCTQILSALSYLHSCSPPIIHGNLTCDSIFIQ-HNGLVKIG 261          

BLAST of CN185226 vs. ExPASy Swiss-Prot
Match: NRBP_DROPS (Nuclear receptor-binding protein homolog OS=Drosophila pseudoobscura pseudoobscura GN=Madm PE=3 SV=2)

HSP 1 Score: 96.6709 bits (239), Expect = 1.213e-19
Identity = 58/177 (32.77%), Postives = 94/177 (53.11%), Query Frame = 3

Query:  177 AGDEAKAHIGYIETDPNGRYGLFEEVLGKG---AMKTVYKAIDEVLGVEVAWNQVRLNELMRSPDDLQRLYSEVHLLSTLKHDSIIRFYTSWIDVDQKT---FNFITEMFTSGTLREYRKKYRR----VDIRAIKSWARQILQGLVYLHSRDPPVIHRDLKCDNIFVHGHLGQVKIG 677
            +GD+++     +E  P GR+    E + +     +  V+ A+D   GVEV WN+V+   +       +++      L  L H +I++F+  W D  Q       FITE  +SG+L+++ K+ +R    + + + + W  QIL  L YLHS  PP+IH +L CD+IF+  H G VKIG
Sbjct:   99 SGDDSEDESEILEESPCGRWLKRREEVDQRDVPGIDCVHLAMDTEEGVEVVWNEVQYANMQELKSQEEKMRQVFDNLLQLDHQNIVKFHRYWTDTQQAERPRVIFITEYMSSGSLKQFLKRTKRNAKRLPLESWRRWCTQILSALSYLHSCTPPIIHGNLTCDSIFIQ-HNGLVKIG 274          

BLAST of CN185226 vs. ExPASy Swiss-Prot
Match: M3K2_MOUSE (Mitogen-activated protein kinase kinase kinase 2 OS=Mus musculus GN=Map3k2 PE=1 SV=2)

HSP 1 Score: 80.4925 bits (197), Expect = 8.999e-15
Identity = 47/144 (32.64%), Postives = 78/144 (54.17%), Query Frame = 3

Query:  249 EVLGKGAMKTVYKAIDEVLGVEVAWNQVRLN-ELMRSPDDLQRLYSEVHLLSTLKHDSIIRFYTSWIDVDQKTFNFITEMFTSGTLREYRKKYRRVDIRAIKSWARQILQGLVYLHSRDPPVIHRDLKCDNIFVHGHLGQVKIG 677
            ++LG+GA   VY   D   G E+A  QV+ N E   +  ++  L  E+ LL  L H+ I+++Y    D  +KT +   E+   G++++  K Y  +     + + RQIL+G+ YLHS    ++HRD+K  NI +    G +K+G
Sbjct:  360 KLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSN--MIVHRDIKGANI-LRDSTGNIKLG 500          

BLAST of CN185226 vs. ExPASy Swiss-Prot
Match: M3K2_HUMAN (Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens GN=MAP3K2 PE=1 SV=2)

HSP 1 Score: 77.411 bits (189), Expect = 7.618e-14
Identity = 46/144 (31.94%), Postives = 77/144 (53.47%), Query Frame = 3

Query:  249 EVLGKGAMKTVYKAIDEVLGVEVAWNQVRLN-ELMRSPDDLQRLYSEVHLLSTLKHDSIIRFYTSWIDVDQKTFNFITEMFTSGTLREYRKKYRRVDIRAIKSWARQILQGLVYLHSRDPPVIHRDLKCDNIFVHGHLGQVKIG 677
            ++LG+GA   VY   D   G E+A  QV+ + +   +  ++  L  E+ LL  L H+ I+++Y    D  +KT +   E    G++++  K Y  +     + + RQIL+G+ YLHS    ++HRD+K  NI +    G VK+G
Sbjct:  360 KLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSN--MIVHRDIKGANI-LRDSTGNVKLG 500