CK937509

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: PE2R_RABIT (Prostaglandin-E(2) 9-reductase OS=Oryctolagus cuniculus GN=AKR1C5 PE=1 SV=1)

HSP 1 Score: 133.265 bits (334), Expect = 2.458e-31
Identity = 81/192 (42.19%), Postives = 111/192 (57.81%), Query Frame = 3

Query:   90 STGKTIPLVGFGT---AQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGF----PFSKEDIEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLER--XXATAKIPPXVNQSGVEPSL 638
            S G  IP++GFGT    + P   A EA K     AI+ G+RH D+A  Y++E+ +G AI   +  G +K R+++F TSKLW      +LV P+L+ SLKNL L+++DLY+IHFP +LKPG          K   + +D    WEAME+C++ GL KSIGVSNF  ++LE        K  P  NQ    P L
Sbjct:   11 SDGHFIPVLGFGTYAPEEVPKSKAMEATKI----AIDAGFRHIDSAYFYKNEKEVGLAIRSKIADGTVK-REDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPGVEIIPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYL 197          

HSP 2 Score: 23.0978 bits (48), Expect = 2.458e-31
Identity = 9/17 (52.94%), Postives = 12/17 (70.59%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPLGA 712
            FC+  GI + AYS LG+
Sbjct:  205 FCKSKGIVLVAYSALGS 221          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: DHB5_MOUSE (Estradiol 17 beta-dehydrogenase 5 OS=Mus musculus GN=Akr1c6 PE=1 SV=1)

HSP 1 Score: 135.576 bits (340), Expect = 2.787e-31
Identity = 82/193 (42.49%), Postives = 117/193 (60.62%), Query Frame = 3

Query:   90 STGKTIPLVGFGT---AQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKEDIEPLDYEGV-----WEAMEECQNLGLTKSIGVSNFACKRLERXXAT--AKIPPXVNQSGVEPSL 638
            S G  IP++GFGT    + P   ATEA K     AI+ G+RH D+A++YQ+E+ +G AI   +  G +K R+++F TSK+W      +LV   L+ SLK L L+++DLYLIHFP+++KPG  +   K++   L Y+ V     WEAME+C++ GL KSIGVSNF  ++LE+       K  P  NQ    P L
Sbjct:   11 SDGHFIPILGFGTYAPQEVPKSKATEATKI----AIDAGFRHIDSASMYQNEKEVGLAIRSKIADGTVK-REDIFYTSKVWCTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMKPGENY-LPKDENGKLIYDAVDICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILKKPGLKYKPVCNQVECHPYL 197          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: ALDR_HUMAN (Aldose reductase OS=Homo sapiens GN=AKR1B1 PE=1 SV=3)

HSP 1 Score: 127.872 bits (320), Expect = 4.170e-31
Identity = 81/193 (41.97%), Postives = 112/193 (58.03%), Query Frame = 3

Query:   90 STGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTG-FPFSKE-DIEPLDYE--GVWEAMEECQNLGLTKSIGVSNFACKRLER--XXATAKIPPXVNQSGVEPSLAAKE 650
            + G  +P++G GT + P G  TEAVK     AI+VGYRH D A +YQ+E  +G AI + LR  ++K R+ELFI SKLW  +  + LV  A Q +L +L L+++DLYLIH+P   KPG   FP  +  ++ P D      W AMEE  + GL K+IG+SNF   ++E        K  P VNQ    P L  ++
Sbjct:    8 NNGAKMPILGLGTWKSPPGQVTEAVKV----AIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK-REELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEK 195          

HSP 2 Score: 27.7202 bits (60), Expect = 4.170e-31
Identity = 10/17 (58.82%), Postives = 14/17 (82.35%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPLGA 712
            +C+  GI +TAYSPLG+
Sbjct:  199 YCQSKGIVVTAYSPLGS 215          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: AK1C4_MACFU (Aldo-keto reductase family 1 member C4 OS=Macaca fuscata fuscata GN=AKR1C4 PE=1 SV=1)

HSP 1 Score: 134.42 bits (337), Expect = 6.210e-31
Identity = 80/188 (42.55%), Postives = 114/188 (60.64%), Query Frame = 3

Query:   96 GKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKED-----IEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXAT--AKIPPXVNQSGVEPSL 638
            G  +P++GFG+   P       V+ + + AIE G+RH D+A +Y +EE +G AI   +  G +K R+++F TSKLW      QLV PAL++SLK L L+++DLYLIHFP++LKPG   P  K++      + +D   +WEAME+C++ GL KSIGVSNF  ++LE        K  P  NQ    P L
Sbjct:   13 GHFMPVLGFGSYAPPEVPRNRVVEVTKL-AIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK-REDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALKPGE-TPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNPGLKYKPVCNQVECHPYL 197          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: AK1C1_PONAB (Aldo-keto reductase family 1 member C1 homolog OS=Pongo abelii GN=AKR1C1 PE=2 SV=1)

HSP 1 Score: 134.42 bits (337), Expect = 6.210e-31
Identity = 79/182 (43.41%), Postives = 111/182 (60.99%), Query Frame = 3

Query:  105 IPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKED----IEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLER--XXATAKIPPXVNQSGVEP 632
            +P++GFGT   P    ++A+ E+   AIE G+RH D+A +Y +EE +G AI   +  G +K R+++F TSKLW      +LV PAL+ SLKNL L+++DLYL+HFPVS+KPG       E+     + +D    WEAME+C++ GL KSIGVSNF  ++LE        K  P  NQ    P
Sbjct:   16 MPVLGFGTYAPPEVPKSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK-REDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLVHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHP 195          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: ALDR_BOVIN (Aldose reductase OS=Bos taurus GN=AKR1B1 PE=1 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 7.071e-31
Identity = 79/192 (41.15%), Postives = 111/192 (57.81%), Query Frame = 3

Query:   93 TGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKEDIEPL----DYEGVWEAMEECQNLGLTKSIGVSNFACKRLER--XXATAKIPPXVNQSGVEPSLAAKE 650
            TG  +P++G GT + P G  TEAVK     AI++GYRH D A +YQ+E  +G A+   L+  ++K R++LFI SKLW  +  + LV  A Q +L +L L+++DLYLIH+P   KPG  F    ED   +    D+   W AMEE  + GL K+IGVSNF   ++E+       K  P VNQ    P L  ++
Sbjct:    8 TGAKMPILGLGTWKSPPGKVTEAVKV----AIDLGYRHIDCAHVYQNENEVGLALQAKLQEQVVK-REDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKDFFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIECHPYLTQEK 194          

HSP 2 Score: 26.9498 bits (58), Expect = 7.071e-31
Identity = 10/17 (58.82%), Postives = 13/17 (76.47%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPLGA 712
            +C   GI +TAYSPLG+
Sbjct:  198 YCNSKGIVVTAYSPLGS 214          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: AK1A1_RAT (Alcohol dehydrogenase [NADP+] OS=Rattus norvegicus GN=Akr1a1 PE=1 SV=2)

HSP 1 Score: 127.487 bits (319), Expect = 9.203e-31
Identity = 70/191 (36.65%), Postives = 112/191 (58.64%), Query Frame = 3

Query:   93 TGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKE-----DIEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXATAKIPPXVNQSGVEPSLAAKE 650
            TG+ +PL+G GT +   G    A+K    +A+ VGYRH D A++Y +E  +GEA+ +++  G    R+ELF+TSKLW    H + V PA++ +L +L LE++DLYL+H+P + + G   PF K        +   Y+  W+A+E     GL K++G+SNF+ ++++   + A + P V Q    P LA  E
Sbjct:   10 TGQKMPLIGLGTWKSEPGQVKAAIK----YALSVGYRHIDCASVYGNETEIGEALKESVGAGKAVPREELFVTSKLWNTKHHPEDVEPAVRKTLADLQLEYLDLYLMHWPYAFERGDN-PFPKNADGTVKYDSTHYKETWKALEALVAKGLVKALGLSNFSSRQIDDVLSVASVRPAVLQVECHPYLAQNE 195          

HSP 2 Score: 26.9498 bits (58), Expect = 9.203e-31
Identity = 9/16 (56.25%), Postives = 13/16 (81.25%), Query Frame = 2

Query:  665 CEXXGIHITAYSPLGA 712
            C+  G+ +TAYSPLG+
Sbjct:  200 CQARGLEVTAYSPLGS 215          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: AK1A1_PIG (Alcohol dehydrogenase [NADP+] OS=Sus scrofa GN=AKR1A1 PE=1 SV=2)

HSP 1 Score: 127.102 bits (318), Expect = 1.198e-30
Identity = 72/191 (37.70%), Postives = 111/191 (58.12%), Query Frame = 3

Query:   93 TGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKE-----DIEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXATAKIPPXVNQSGVEPSLAAKE 650
            TG+ +PL+G GT +   G    A+K    +A+ VGYRH D AAIY +E  +GEA+ + +  G    R+ELF+TSKLW    H + V PAL+ +L +L LE++DLYL+H+P + + G   PF K        +   Y+  W+A+E     GL +++G+SNF+ ++++   + A + P V Q    P LA  E
Sbjct:   10 TGQKMPLIGLGTWKSEPGQVKAAIK----YALTVGYRHIDCAAIYGNELEIGEALTETVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDN-PFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRPAVLQVECHPYLAQNE 195          

HSP 2 Score: 26.9498 bits (58), Expect = 1.198e-30
Identity = 9/16 (56.25%), Postives = 13/16 (81.25%), Query Frame = 2

Query:  665 CEXXGIHITAYSPLGA 712
            C+  G+ +TAYSPLG+
Sbjct:  200 CQARGLEVTAYSPLGS 215          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: AK1A1_PONAB (Alcohol dehydrogenase [NADP+] OS=Pongo abelii GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 127.487 bits (319), Expect = 1.560e-30
Identity = 74/191 (38.74%), Postives = 110/191 (57.59%), Query Frame = 3

Query:   93 TGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKED-----IEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXATAKIPPXVNQSGVEPSLAAKE 650
            TG+ +PL+G GT +   G    AVK    +A+ VGYRH D AAIY +E  +GEA+ + +  G    R+ELF+TSKLW    H + V PALQ +L +L LE++DLYL+H+P + + G   PF K        +   Y+  W+A+E     GL +++G+SNF  ++++   + A + P V Q    P LA  E
Sbjct:   10 TGQKMPLIGLGTWKSEPGQVKAAVK----YALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALQKTLADLQLEYLDLYLMHWPYAFERGDN-PFPKNADGTICYDSTHYKETWKALEALVAKGLVRALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNE 195          

HSP 2 Score: 26.1794 bits (56), Expect = 1.560e-30
Identity = 9/16 (56.25%), Postives = 13/16 (81.25%), Query Frame = 2

Query:  665 CEXXGIHITAYSPLGA 712
            C+  G+ +TAYSPLG+
Sbjct:  200 CQARGLAVTAYSPLGS 215          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: AKC1H_MOUSE (Aldo-keto reductase family 1 member C18 OS=Mus musculus GN=Akr1c18 PE=2 SV=2)

HSP 1 Score: 132.88 bits (333), Expect = 1.807e-30
Identity = 76/168 (45.24%), Postives = 106/168 (63.10%), Query Frame = 3

Query:   96 GKTIPLVGFGTAQFPFGAATEAVK----ESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKED----IEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLE 575
            G +IP++GFGT      A  E +K    ES   AI+VG+ H D + +YQ+EE +G+AI   +  G +K R+++F TSKLW      +LV P+L+ SL+ L L+++DLYLIHFPVSLKPG       E      + +D    WEAME+C++ GL KSIGVSNF  ++LE
Sbjct:   13 GHSIPVLGFGTY-----ATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAILSKIEDGTVK-REDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLE 174