CK937509

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: ALDR_MOUSE (Aldose reductase OS=Mus musculus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 124.02 bits (310), Expect = 9.907e-30
Identity = 77/193 (39.90%), Postives = 112/193 (58.03%), Query Frame = 3

Query:   90 STGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTG-FPF-SKEDIEP--LDYEGVWEAMEECQNLGLTKSIGVSNFACKRLER--XXATAKIPPXVNQSGVEPSLAAKE 650
            + G  +P +G GT + P G  TEAVK     AI++GYRH D A +YQ+E+ +G A+ + L+  ++K R +LFI SKLW     + +V  A Q +L +L L+++DLYLIH+P   KPG   FP  +  ++ P   D+   W AME+  + GL K+IGVSNF   ++ER       K  P VNQ    P L  ++
Sbjct:    8 NNGTKMPTLGLGTWKSPPGQVTEAVKV----AIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQVVK-RQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEK 195          

HSP 2 Score: 26.9498 bits (58), Expect = 9.907e-30
Identity = 10/17 (58.82%), Postives = 13/17 (76.47%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPLGA 712
            +C   GI +TAYSPLG+
Sbjct:  199 YCHSKGIVVTAYSPLGS 215          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: ALRB_DICDI (Aldose reductase B OS=Dictyostelium discoideum GN=alrB PE=3 SV=2)

HSP 1 Score: 122.865 bits (307), Expect = 9.911e-30
Identity = 76/198 (38.38%), Postives = 107/198 (54.04%), Query Frame = 3

Query:  105 IPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPG-----TGFPFSKEDIEP----LDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXATAKIPPXVNQSGVEPSLAAKEAERFSVR 671
            IP++G GT     GA    V ++V  A++ GYRH D AAIY +E+ +G A+ +    G IK R+++F  SKLW    H  LV    + +L++LGLE++DLYLIH+P++ +       T  P    D EP    +     W+ ME+    GL KSIGVSNF  + L      AKI P +NQ  V P L+    + F  R
Sbjct:   17 IPMIGLGTYN---GAKVGEVGDAVKVALKSGYRHIDGAAIYMNEKEIGHALKEVFAEGEIK-REDIFYVSKLWNSCHHASLVRKHCEKTLEDLGLEYLDLYLIHWPIAFENADPSGTTTQPLRDSDGEPVLAAVSIRETWQEMEKLVEYGLVKSIGVSNFNVQNLVDLLTYAKIKPAINQVEVHPYLSQPNLKYFCDR 210          

HSP 2 Score: 28.1054 bits (61), Expect = 9.911e-30
Identity = 11/16 (68.75%), Postives = 13/16 (81.25%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPLG 709
            FC+  GI +TAYSPLG
Sbjct:  207 FCDRYGIVLTAYSPLG 222          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: AK1CD_MESAU (Aldo-keto reductase family 1 member C13 OS=Mesocricetus auratus GN=AKR1C13 PE=1 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 1.171e-29
Identity = 70/165 (42.42%), Postives = 103/165 (62.42%), Query Frame = 3

Query:   96 GKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPG-TGFPFSKED---IEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLER 578
            G  IP +GFGT + P         E+   AI VGYRH DTA  YQ EE +G+AI   ++ G++K R+++FIT+KLW      +LV P+L+     L LEH+DL+++H+PV +K G   FP  ++    ++ +D+   WEA+E+  + GL KSIGVSNF  ++LER
Sbjct:   13 GHCIPALGFGTYK-PIEVPKSKAMEAANLAIGVGYRHIDTAYAYQIEEEIGQAIQSNIKAGIVK-REDMFITTKLWCTCFQPELVRPSLEKXXXKLQLEHVDLFIMHYPVPMKAGDNDFPLDEQGKLLLDTVDFCATWEALEKXXDAGLVKSIGVSNFNMRQLER 175          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: ALDR_RAT (Aldose reductase OS=Rattus norvegicus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 123.25 bits (308), Expect = 1.680e-29
Identity = 77/193 (39.90%), Postives = 112/193 (58.03%), Query Frame = 3

Query:   90 STGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTG-FPF-SKEDIEP--LDYEGVWEAMEECQNLGLTKSIGVSNFACKRLER--XXATAKIPPXVNQSGVEPSLAAKE 650
            + G  +P +G GT + P G  TEAVK     AI++GYRH D A +YQ+E+ +G A+ + L+  ++K R +LFI SKLW     + +V  A Q +L +L L+++DLYLIH+P   KPG   FP  +  ++ P   D+   W AME+  + GL K+IGVSNF   ++ER       K  P VNQ    P L  ++
Sbjct:    8 NNGTKMPTLGLGTWKSPPGQVTEAVKV----AIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVK-RQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEK 195          

HSP 2 Score: 26.9498 bits (58), Expect = 1.680e-29
Identity = 10/17 (58.82%), Postives = 13/17 (76.47%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPLGA 712
            +C   GI +TAYSPLG+
Sbjct:  199 YCHCKGIVVTAYSPLGS 215          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: AK1BA_HUMAN (Aldo-keto reductase family 1 member B10 OS=Homo sapiens GN=AKR1B10 PE=1 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 2.187e-29
Identity = 78/200 (39.00%), Postives = 110/200 (55.00%), Query Frame = 3

Query:   90 STGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKEDIEPLDYEG-----------VWEAMEECQNLGLTKSIGVSNFACKRLER--XXATAKIPPXVNQSGVEPSLAAKE 650
            ST   +P+VG GT + P G   EAVK     AI+ GYRH D A +YQ+E  +GEAI + ++   +K R++LFI SKLW     R LV  A + +LK+L L ++D+YLIH+P   K G       +D+ P D +G            WEAMEE  + GL K++GVSNF+  ++E+       K  P  NQ    P L  ++
Sbjct:    8 STKAKMPIVGLGTWKSPLGKVKEAVKV----AIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVK-REDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSG-------DDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEK 195          

HSP 2 Score: 27.335 bits (59), Expect = 2.187e-29
Identity = 10/17 (58.82%), Postives = 13/17 (76.47%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPLGA 712
            +C   GI +TAYSPLG+
Sbjct:  199 YCHSKGITVTAYSPLGS 215          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: AK1C3_HUMAN (Aldo-keto reductase family 1 member C3 OS=Homo sapiens GN=AKR1C3 PE=1 SV=3)

HSP 1 Score: 128.642 bits (322), Expect = 2.846e-29
Identity = 79/192 (41.15%), Postives = 111/192 (57.81%), Query Frame = 3

Query:   96 GKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKEDIEPLDYEG-----------VWEAMEECQNLGLTKSIGVSNFACKRLER--XXATAKIPPXVNQSGVEP 632
            G  +P++GFGT   P    ++A++ + + AIE G+RH D+A +Y +EE +G AI   +  G +K R+++F TSKLW      +LV PAL+ SLK   L+++DLYLIH P+SLKPG       E++ P D  G            WEAME+C++ GL KSIGVSNF  ++LE        K  P  NQ    P
Sbjct:   13 GHFMPVLGFGTYAPPEVPRSKALEVTKL-AIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK-REDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG-------EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHP 195          

HSP 2 Score: 20.7866 bits (42), Expect = 2.846e-29
Identity = 8/18 (44.44%), Postives = 12/18 (66.67%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPLGAK 715
            FC+   I + AYS LG++
Sbjct:  205 FCKSKDIVLVAYSALGSQ 222          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: A1A1A_DANRE (Alcohol dehydrogenase [NADP+] A OS=Danio rerio GN=akr1a1a PE=2 SV=2)

HSP 1 Score: 127.102 bits (318), Expect = 3.705e-29
Identity = 74/191 (38.74%), Postives = 106/191 (55.50%), Query Frame = 3

Query:   90 STGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGF----PFSKEDIEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXATAKIPPXVNQSGVEPSLAAKE 650
            STG+ +P VG GT    + +A   VK++V+ A++ GYRH D AA Y +E  +GEA+ + L  G    RD++F+TSKLW    H   V  A + SL +L L ++DLYLIH+P++   G       P      +   Y   W AME+  + GL K+IG+SNF  K+++   + AK  P VNQ    P L   E
Sbjct:    8 STGQRMPTVGLGT----WKSAPGQVKQAVLAALDCGYRHIDCAAAYSNEREVGEALTERLGPGKSLRRDDIFVTSKLWNTKHHPDDVEEACRRSLSDLRLSYLDLYLIHWPMAFGRGDELIPRHPDGTIQYDDTHYRDTWAAMEKLVDQGLAKAIGLSNFNAKQIDDILSIAKHKPVVNQVECHPYLVQAE 194          

HSP 2 Score: 21.9422 bits (45), Expect = 3.705e-29
Identity = 8/16 (50.00%), Postives = 11/16 (68.75%), Query Frame = 2

Query:  665 CEXXGIHITAYSPLGA 712
            C    + +TAYSPLG+
Sbjct:  199 CWSRNLTVTAYSPLGS 214          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: AK1D1_HUMAN (3-oxo-5-beta-steroid 4-dehydrogenase OS=Homo sapiens GN=AKR1D1 PE=1 SV=1)

HSP 1 Score: 121.324 bits (303), Expect = 1.065e-28
Identity = 68/173 (39.31%), Postives = 100/173 (57.80%), Query Frame = 3

Query:   90 STGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKEDIEPLDYEG-----------VWEAMEECQNLGLTKSIGVSNFACKRLE 575
            S G +IP++G GT   P      A   SV  AI+ GYRH D A IYQ+E  +GEAI + +  G ++ R+++F   KLW  +   ++V P L+ +L+ L L+++DLY+I  P++ KPG       ++I P D  G            WEAME C++ GL KS+GVSNF  ++LE
Sbjct:   13 SDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVR-REDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPG-------DEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLE 177          

HSP 2 Score: 26.1794 bits (56), Expect = 1.065e-28
Identity = 11/16 (68.75%), Postives = 12/16 (75.00%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPLG 709
            FC+   I ITAYSPLG
Sbjct:  208 FCQQHDIVITAYSPLG 223          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: AK1A1_XENLA (Alcohol dehydrogenase [NADP+] OS=Xenopus laevis GN=akr1a1 PE=2 SV=1)

HSP 1 Score: 123.635 bits (309), Expect = 1.804e-28
Identity = 71/190 (37.37%), Postives = 110/190 (57.89%), Query Frame = 3

Query:   93 TGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGF----PFSKEDIEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXATAKIPPXVNQSGVEPSLAAKE 650
            TG+ +PL+G GT    + +A   VK++V +A+ VGYRH D A +Y +E  +GEAI +++       R+E+F+TSKLW    H   V  AL+ +L+ L L+++DLYL+H+P + K G       P      +  DY+  W+AME+    GL K+IG+SNF  ++++   + A + P V Q    P LA  E
Sbjct:   12 TGQKMPLIGLGT----WKSAPGQVKDAVKYALGVGYRHIDCAFVYGNETEVGEAIKESVGPDKGLKREEVFVTSKLWNNKHHPDDVECALRKTLQELQLDYLDLYLMHWPYAFKRGDQVFPQNPDGSVQYDLTDYKDTWKAMEKLVEKGLAKAIGLSNFNKRQMDDILSIATVKPAVLQVECHPYLAQNE 197          

HSP 2 Score: 23.0978 bits (48), Expect = 1.804e-28
Identity = 8/16 (50.00%), Postives = 11/16 (68.75%), Query Frame = 2

Query:  665 CEXXGIHITAYSPLGA 712
            C   G+ +T YSPLG+
Sbjct:  202 CRSHGLVLTGYSPLGS 217          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: ALD2_CRIGR (Aldose reductase-related protein 2 OS=Cricetulus griseus GN=AKR1B8 PE=1 SV=3)

HSP 1 Score: 119.398 bits (298), Expect = 1.806e-28
Identity = 77/194 (39.69%), Postives = 108/194 (55.67%), Query Frame = 3

Query:   90 STGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKED-----IEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLER--XXATAKIPPXVNQSGVEPSLAAKE 650
            ST   +P+VG GT Q P G   EAVK     AI+ GYRH D A  Y +E  +GEAI + ++   ++ R++LFI SKLW     R+L+  A Q +L +L L+++DLYLIH+P  L+PG    F K+D        + +   WE MEE  + GL K++GVSNF   ++ER       K  P  NQ    P L  ++
Sbjct:    8 STKAKMPIVGLGTWQSPPGQVKEAVKV----AIDAGYRHIDCAYAYYNEHEVGEAIQEKIKEKAVR-REDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKEL-FPKDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPVTNQVECHPYLTQEK 195          

HSP 2 Score: 27.335 bits (59), Expect = 1.806e-28
Identity = 10/17 (58.82%), Postives = 13/17 (76.47%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPLGA 712
            +C   GI +TAYSPLG+
Sbjct:  199 YCHSKGITVTAYSPLGS 215