CK937509

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: ALD2_MOUSE (Aldose reductase-related protein 2 OS=Mus musculus GN=Akr1b8 PE=1 SV=2)

HSP 1 Score: 113.235 bits (282), Expect = 9.438e-27
Identity = 74/194 (38.14%), Postives = 107/194 (55.15%), Query Frame = 3

Query:   90 STGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKED-----IEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLER--XXATAKIPPXVNQSGVEPSLAAKE 650
            ST   +P+VG GT + P       VKE+V  AI+ GYRH D A  Y +E  +GEAI + ++   ++ R++LFI SKLW     ++L+  A Q +L +L L+++DLYLIH+P  L+PG    F K+D          +   WE MEE  + GL K++GVSNF   ++ER       K  P  NQ    P L  ++
Sbjct:    8 STKAKMPIVGLGTWKSP----PNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEKAVQ-REDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKEL-FPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEK 195          

HSP 2 Score: 27.7202 bits (60), Expect = 9.438e-27
Identity = 10/17 (58.82%), Postives = 13/17 (76.47%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPLGA 712
            +C   GI +TAYSPLG+
Sbjct:  199 YCHSKGISVTAYSPLGS 215          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: AK1D1_RABIT (3-oxo-5-beta-steroid 4-dehydrogenase OS=Oryctolagus cuniculus GN=AKR1D1 PE=2 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 4.588e-26
Identity = 67/176 (38.07%), Postives = 98/176 (55.68%), Query Frame = 3

Query:   81 PLGSTGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKEDIEPLDYEG-----------VWEAMEECQNLGLTKSIGVSNFACKRLE 575
            PLG  G +IP++G GT   P      +   SV  AI+ GYRH D A IYQ+E  +GE   + +  G ++ R+++F   KLW  +    +V P L+ +LK L L++IDLY+I  P++ KPG       + + P D  G            WEA+E C++ GL KS+GVSNF  ++LE
Sbjct:   11 PLGD-GNSIPIIGLGTYSEPKTTPKGSCATSVKIAIDTGYRHIDGAYIYQNEHEVGETFREKIAEGKVR-REDIFYCGKLWATNHDPVMVRPTLERTLKVLKLDYIDLYIIEIPMAFKPG-------DVVYPRDENGKWLYHKTNLCATWEALEACKDAGLVKSLGVSNFNRQQLE 177          

HSP 2 Score: 24.2534 bits (51), Expect = 4.588e-26
Identity = 10/16 (62.50%), Postives = 11/16 (68.75%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPLG 709
            FC+   I I AYSPLG
Sbjct:  208 FCQQHDIIIVAYSPLG 223          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: YDG7_SCHPO (Uncharacterized oxidoreductase C26F1.07 OS=Schizosaccharomyces pombe GN=SPAC26F1.07 PE=2 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 7.775e-26
Identity = 71/189 (37.57%), Postives = 104/189 (55.03%), Query Frame = 3

Query:   96 GKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTG-FPFSKED---IEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXATAKIPPXVNQSGVEPSLAAKE 650
            G  IP +G GT    + +     K +V  A++ GYRH D AAIY +E+ +G+ I ++   G+   R ++++TSKLW      + V  AL+ +LK+L L+++D YLIH+PVS K G   FP  K+     E    E  W+AME+    G  + IG+SNF    LER    AK+ P V+Q  + P L   E
Sbjct:   21 GSKIPGLGLGT----WRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIKES---GV--PRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQMELHPFLPQTE 200          

HSP 2 Score: 26.9498 bits (58), Expect = 7.775e-26
Identity = 10/15 (66.67%), Postives = 12/15 (80.00%), Query Frame = 2

Query:  677 GIHITAYSPLGAKGT 721
            GIH+TAYSP G + T
Sbjct:  209 GIHVTAYSPFGNQNT 223          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: YTBE_BACSU (Uncharacterized oxidoreductase ytbE OS=Bacillus subtilis GN=ytbE PE=1 SV=1)

HSP 1 Score: 116.316 bits (290), Expect = 1.015e-25
Identity = 75/190 (39.47%), Postives = 98/190 (51.58%), Query Frame = 3

Query:   96 GKTIPLVGFGTAQFPFGAA-TEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKEDIEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXATAKIPPXVNQSGVEPSLAAKEAERF 662
            G  +P  G G  Q   G+    AVK ++VH    GYR  DTAAIY +E  +GE I + +    I SR++LFITSK+W      +  L A +TSL  LGL+++DLYLIH+PV  K                Y+  W A+E     G  K+IGVSNF    LE     A+I P +NQ    P L  KE  R+
Sbjct:   14 GVEMPWFGLGVFQVEEGSELVNAVKTAIVH----GYRSIDTAAIYGNEAGVGEGIREGIEEAGI-SREDLFITSKVWNADLGYEETLAAFETSLSKLGLDYLDLYLIHWPVEGK----------------YKEAWRALETLYKEGRIKAIGVSNFQIHHLEDLMTAAEIKPMINQVEFHPRLTQKELIRY 182          

HSP 2 Score: 21.1718 bits (43), Expect = 1.015e-25
Identity = 7/15 (46.67%), Postives = 11/15 (73.33%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPL 706
            +C+  GI + A+SPL
Sbjct:  182 YCQNQGIQMEAWSPL 196          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: XYL1_CANPA (NADH-dependent D-xylose reductase OS=Candida parapsilosis GN=XYL1 PE=1 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 1.026e-25
Identity = 76/209 (36.36%), Postives = 111/209 (53.11%), Query Frame = 3

Query:   51 MKTMVSIPEAPLGSTGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKP-------------GTGFPFSKEDIEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXATAKIPPXVNQSGVEPSL 638
            M T  + P   L S G  IPLVGFG  +       +   + +  AI+ GYR FD A  Y +E+ +GE I +A++ G++K R+ELFITSKLW     ++ V  AL  +L +L L+++DL+ IHFP++ KP             G G  +S E++  LD    W A+E+  + GL KSIG+SNF+ + +        I P   Q    P L
Sbjct:    1 MSTATASPAVKLNS-GYEIPLVGFGCWKL----TNDVASDQIYRAIKSGYRLFDGAEDYANEQEVGEGIKRAIKEGIVK-REELFITSKLWNSFHDKKNVEVALMKTLSDLNLDYVDLFYIHFPIAQKPVPIEKKYPPGFYCGDGDKWSIEEVPLLD---TWRALEKLVDQGLAKSIGISNFSAQLIYDLIRGCTIKPVALQIEHHPYL 200          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: AK1D1_RAT (3-oxo-5-beta-steroid 4-dehydrogenase OS=Rattus norvegicus GN=Akr1d1 PE=1 SV=1)

HSP 1 Score: 116.316 bits (290), Expect = 1.750e-25
Identity = 73/189 (38.62%), Postives = 106/189 (56.08%), Query Frame = 3

Query:   96 GKTIPLVGFGTAQFPF---GAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKEDIEPLDYE-----GVWEAMEECQNLGLTKSIGVSNFACKRLE--RXXATAKIPPXVNQSGVEP 632
            G +IP++G GT   P    G    AVK     AI+ GYRH D A +Y++E  +GEAI + +  G +K R+E+F   KLW      ++V PAL+ +L+ L L++IDLY+I  P++ KPG  F + K++   + Y        WEA+E C++ GL KS+GVSNF  ++LE        K  P  NQ    P
Sbjct:   15 GNSIPIIGLGTYSDPRPVPGKTFIAVKT----AIDEGYRHIDGAYVYRNEHEVGEAIREKVAEGKVK-REEIFYCGKLWSTDHDPEMVRPALERTLQTLKLDYIDLYIIEMPMAFKPGEEF-YPKDENGRVIYHKSNLCATWEALEACKDAGLVKSLGVSNFNRRQLEVILNKPGLKYKPVTNQVECHP 197          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: XYL2_CANTR (NADPH-dependent D-xylose reductase II,III OS=Candida tropicalis GN=xyrB PE=1 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 2.286e-25
Identity = 80/209 (38.28%), Postives = 110/209 (52.63%), Query Frame = 3

Query:   51 MKTMVSIPEAPLGSTGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLK-------------PGTGFPFSKEDIEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXATAKIPPXVNQSGVEPSL 638
            M T  +IP   L S G  +PLVGFG     +    E   + + +AI+ GYR FD A  Y +E+ +GE I +A++ GL+K R+ELFITSKLW      + V  AL  +L +L L+++DL+LIHFP++ K              G G  F  ED+  LD    W+A+E+    G  KSIG+SNF    +      A I P V Q    P L
Sbjct:    1 MSTTPTIPTIKLNS-GYEMPLVGFGC----WKVNNETAADQIYNAIKTGYRLFDGAEDYGNEKEVGEGINRAIKEGLVK-REELFITSKLWNNFHDPKNVETALNKTLSDLNLDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGDNFHYEDVPLLD---TWKALEKLVEAGKIKSIGISNFTGALIYDLIRGATIKPAVLQIEHHPYL 200          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: DKGA_CORSC (2,5-diketo-D-gluconic acid reductase A OS=Corynebacterium sp. (strain ATCC 31090) GN=dkgA PE=1 SV=3)

HSP 1 Score: 115.931 bits (289), Expect = 2.286e-25
Identity = 75/196 (38.27%), Postives = 103/196 (52.55%), Query Frame = 3

Query:   63 VSIPEAPLGSTGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKEDIEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXATAKIPPXVNQSGVEPSLAAKE 650
            +++P   L   G +IP +G+G  + P      AV+E    A+EVGYRH DTAAIY +EE +G AIA +   G+  +RD+LFIT+KLW           A+  SL  L L+ +DLYL+H+P                   +Y   WE M E +  GLT+SIGVSN     LER  A   + P VNQ  + P+   +E
Sbjct:    1 MTVPSIVLND-GNSIPQLGYGVFKVPPADTQRAVEE----ALEVGYRHIDTAAIYGNEEGVGAAIAAS---GI--ARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAAD--------------NYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHPAYQQRE 172          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: ALRC_DICDI (Aldose reductase C OS=Dictyostelium discoideum GN=alrC PE=3 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 6.402e-25
Identity = 66/198 (33.33%), Postives = 106/198 (53.54%), Query Frame = 3

Query:   96 GKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLKPGTGFPFSKED---------IEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXATAKIPPXVNQSGVEPSLAAKEAERF 662
            G  IP +G GT    +      V +++ +A++ GYRH D AA Y +E+ +G ++ +  + G IK R+++F TSKLW    +  LV+     ++++LG+ ++DLYLIH+P++ +       + E          I P+     W+ ME+   LGL KSIGVSNF  + L      AKI P VNQ  + P L   + + +
Sbjct:   22 GNQIPSIGLGTY---YSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEGEIK-REDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQEY 215          

HSP 2 Score: 22.7126 bits (47), Expect = 6.402e-25
Identity = 8/16 (50.00%), Postives = 11/16 (68.75%), Query Frame = 2

Query:  662 FCEXXGIHITAYSPLG 709
            +C+   I + AYSPLG
Sbjct:  215 YCDKYEIKLVAYSPLG 230          

BLAST of CK937509 vs. ExPASy Swiss-Prot
Match: XYL1_CANTR (NAD(P)H-dependent D-xylose reductase I,II OS=Candida tropicalis GN=xyrA PE=3 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 6.650e-25
Identity = 80/209 (38.28%), Postives = 110/209 (52.63%), Query Frame = 3

Query:   51 MKTMVSIPEAPLGSTGKTIPLVGFGTAQFPFGAATEAVKESVVHAIEVGYRHFDTAAIYQSEEPLGEAIAQALRLGLIKSRDELFITSKLWFGHAHRQLVLPALQTSLKNLGLEHIDLYLIHFPVSLK-------------PGTGFPFSKEDIEPLDYEGVWEAMEECQNLGLTKSIGVSNFACKRLERXXATAKIPPXVNQSGVEPSL 638
            M T  +IP   L S G  +PLVGFG  +     A +     + +AI+ GYR FD A  Y +E+ +GE I +A++ GL+K R+ELFITSKLW      + V  AL  +L +L L+++DL+LIHFP++ K              G G  F  ED+  LD    W+A+E+    G  KSIG+SNF    +      A I P V Q    P L
Sbjct:    1 MSTTPTIPTIKLNS-GYEMPLVGFGCWKVTNATAAD----QIYNAIKTGYRLFDGAEDYGNEKEVGEGINRAIKEGLVK-REELFITSKLWNNFHDPKNVETALNKTLSDLNLDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGDNFHYEDVPLLD---TWKALEKLVEAGKIKSIGISNFTGALIYDLIRGATIKPAVLQIEHHPYL 200