CX043274

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: MTHR1_SCHPO (Methylenetetrahydrofolate reductase 1 OS=Schizosaccharomyces pombe GN=met9 PE=1 SV=1)

HSP 1 Score: 208.764 bits (530), Expect = 3.104e-53
Identity = 117/284 (41.20%), Postives = 161/284 (56.69%), Query Frame = 3

Query:    3 DPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTLHLYTLNMEKSALAILLNLGLIEESKISRSLPWRPPTNV---------FRVKEDVRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNPSYGALSDHQFMRPRSRDKKLHEEWAVP 827
            DP    D + + + GF  A DLV++IR+ Y D F I VAGYPEG+     PD     +     + +LK KVD GAD I+TQ+FYD D F+ +V+  R  GI  PI PGIMPI  +  F+R   +   KIP      L P+KD++E V+  G+ L  EMC+K++A GI  LH YT+N+EK+   I+  LGL++E+      P     NV          R+ E VRPIFW  R +SY+SRT  WD+ P GRWGDSR+P++G     ++   R   K++   W  P
Sbjct:  114 DPVKDTD-WTEGESGFRYASDLVRYIRTHYNDEFCIGVAGYPEGY----SPD-----DDIDESIKHLKLKVDEGADFIVTQMFYDVDNFIAWVDKVRAAGINIPIFPGIMPIQAWDSFIRRAKWSGVKIPQHFMDTLVPVKDDDEGVRERGVELIVEMCRKLIASGITRLHFYTMNLEKAVKMIIERLGLLDEN----LAPIVDTNNVELTNASSQDRRINEGVRPIFWRTRNESYVSRTDQWDELPHGRWGDSRSPAFGEFDAIRY-GLRMSPKEITTSWGSP 382          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: MTHR2_SCHPO (Methylenetetrahydrofolate reductase 2 OS=Schizosaccharomyces pombe GN=met11 PE=2 SV=2)

HSP 1 Score: 147.132 bits (370), Expect = 1.109e-34
Identity = 99/308 (32.14%), Postives = 146/308 (47.40%), Query Frame = 3

Query:    3 DPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITC----PIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAH---GIKTLHLYTLNMEKSALAILLNLGLI-----------EESKISRS------------------LPWRPP-----TNVFRVKED-----------VRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNPSYGALSDH 770
            DPP   D +      F  A+DLV++IR  YGDYF I VA YPEGH D+  P+    ++    D+ +L +KV+AGAD IITQ+FY+ + F+KF N  R          PI+P IMPI +Y    RMT  C   +P+ +   L   K ++EA+K  G+    +M KKI+ +    +   H  TLN+E+S   IL N GL+           E+ K+ R+                  +P + P     +N+F   +                F  +     L R   WD +  GR+GD R+P+YG +  +
Sbjct:  113 DPPLNSDHWEGKVSEFEHAVDLVRYIREKYGDYFCIGVAAYPEGHVDSNVPE---LSKDPLRDIPFLIEKVEAGADFIITQIFYEPEAFIKFENFVRNHSSNALRNIPIIPAIMPIQSYGSLKRMTRLCGCSVPSSLMQRLNAAKPDDEAIKNIGVEHIVDMIKKIMDNVQGRVHGFHFCTLNLERSVALILKNSGLLTKRWKQVESEMEDEKLLRTTRKRLSLDEPAELHNQVVVPSQQPVADKSSNLFVTSKQSSVSGHKDNLTEEAPFSVSEGSGVLGRQANWDDFTNGRFGDPRSPAYGEIDGY 417          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: METF_AQUAE (5,10-methylenetetrahydrofolate reductase OS=Aquifex aeolicus GN=metF PE=3 SV=1)

HSP 1 Score: 136.346 bits (342), Expect = 1.958e-31
Identity = 69/184 (37.50%), Postives = 99/184 (53.80%), Query Frame = 3

Query:    3 DPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTLHLYTLNMEKSALAI 554
            D P  +  +   +G    A +LV+ IR  +GD+F I VA YPEGHP++          + + ++ Y K+KV+AGAD  ITQ+F+  D + +FV  C+  GI   I+PGIMPI N+K   +    C   IP  +   LE ++D  E VK  GI      C  ++ HG+  LH YTLN   + L I
Sbjct:  109 DVPRDKPDWRPPKGACKYAKELVELIRKEFGDWFSIGVASYPEGHPES---------PNLEWEVKYFKEKVEAGADFSITQMFFVNDYYYRFVEMCKNAGIDISIIPGIMPITNFKQIRKFASLCGATIPQSLIEKLEKVEDKPEEVKKIGIEFAINQCLDLIEHGVPGLHFYTLNKSDATLKI 283          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: MTHR1_YEAST (Methylenetetrahydrofolate reductase 1 OS=Saccharomyces cerevisiae GN=MET12 PE=1 SV=2)

HSP 1 Score: 124.405 bits (311), Expect = 7.698e-28
Identity = 76/192 (39.58%), Postives = 110/192 (57.29%), Query Frame = 3

Query:    3 DPPHGQDKF--VQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQ-IGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEP-IKDNEEAVKAYGIHLGAEMCKKI---LAHGIKTLHLYTLNMEKSALAIL 557
            DPP G+D       +  F  A+DLV++I+ +YGD F + VA YPEGH +    +     +    DL+YLK+KV+AGAD +ITQLFYD + FL F    R+ I    P+ PG+MPIN+Y  F R        IP  I +   P I+ ++ AVK+ G+ +  E+ ++I    +  IK  H YTLN+EK+   I+
Sbjct:  110 DPPIGEDWLDSQSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEG---EAEGHEQDPLKDLVYLKEKVEAGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPPAILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIV 298          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: METF_HAEIN (5,10-methylenetetrahydrofolate reductase OS=Haemophilus influenzae GN=metF PE=3 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 6.099e-25
Identity = 64/172 (37.21%), Postives = 95/172 (55.23%), Query Frame = 3

Query:   57 ALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTLHLYTLNMEKSALAILLNLGL 572
            A DLV+ +RS     F I+VA YPE HP+          +S Q+DL+ LK+K+DAGA+ +ITQ F+D + +L+F + C  IGI   IVPGI+P+ N+K   +M  F   KIPA +  A + + ++          +  +M K +   G+   H YTLN  +   AI   LG+
Sbjct:  130 ASDLVELLRSVAD--FDISVAAYPEVHPEA---------KSAQADLINLKRKIDAGANHVITQFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGLDNDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGV 290          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: METF_NEIMB (5,10-methylenetetrahydrofolate reductase OS=Neisseria meningitidis serogroup B GN=metF PE=1 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 7.966e-25
Identity = 64/172 (37.21%), Postives = 96/172 (55.81%), Query Frame = 3

Query:   57 ALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTLHLYTLNMEKSALAILLNLGL 572
            A DLVK +RS     F I+VA YPE HP+          +S Q+DL+ LK+K+DAGA+ +ITQ F+D + +L+F + C  +GI   IVPGI+P+ N+K   +M      KIP+ ++   E + D++         +  +M K +   G+K  H YTLN  +   AI   LG+
Sbjct:  130 AEDLVKLLRSVAD--FDISVAAYPEVHPEA---------KSAQADLINLKRKIDAGANHVITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGV 290          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: METF_SHIFL (5,10-methylenetetrahydrofolate reductase OS=Shigella flexneri GN=metF PE=3 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 1.359e-24
Identity = 59/157 (37.58%), Postives = 89/157 (56.69%), Query Frame = 3

Query:  102 FGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTLHLYTLNMEKSALAILLNLGL 572
            F I+VA YPE HP+          +S Q+DLL LK+KVDAGA+  ITQ F+D + +L+F + C   GI   I+PGI+P++N+K   +       +IPA +    + + D+ E  K  G ++  +M K +   G+K  H YTLN  + + AI   LG+
Sbjct:  145 FDISVAAYPEVHPEA---------KSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGV 292          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: METF_ECOLI (5,10-methylenetetrahydrofolate reductase OS=Escherichia coli (strain K12) GN=metF PE=1 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 1.359e-24
Identity = 59/157 (37.58%), Postives = 89/157 (56.69%), Query Frame = 3

Query:  102 FGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTLHLYTLNMEKSALAILLNLGL 572
            F I+VA YPE HP+          +S Q+DLL LK+KVDAGA+  ITQ F+D + +L+F + C   GI   I+PGI+P++N+K   +       +IPA +    + + D+ E  K  G ++  +M K +   G+K  H YTLN  + + AI   LG+
Sbjct:  145 FDISVAAYPEVHPEA---------KSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGV 292          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: METF_SALTY (5,10-methylenetetrahydrofolate reductase OS=Salmonella typhimurium GN=metF PE=3 SV=2)

HSP 1 Score: 112.079 bits (279), Expect = 3.954e-24
Identity = 58/157 (36.94%), Postives = 90/157 (57.32%), Query Frame = 3

Query:  102 FGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTLHLYTLNMEKSALAILLNLGL 572
            F I+VA YPE HP+          +S Q+DLL LK+KVDAGA+  ITQ F+D + +L+F + C   GI   I+PGI+P++N+K   +       +IP+ ++   E + ++ E  K  G ++  +M K +   G+K  H YTLN  + + AI   LG+
Sbjct:  145 FDISVAAYPEVHPEA---------KSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFEGLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGV 292          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: METF_PECCC (5,10-methylenetetrahydrofolate reductase OS=Pectobacterium carotovorum subsp. carotovorum GN=metF PE=3 SV=1)

HSP 1 Score: 110.538 bits (275), Expect = 1.150e-23
Identity = 62/172 (36.05%), Postives = 95/172 (55.23%), Query Frame = 3

Query:   57 ALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTLHLYTLNMEKSALAILLNLGL 572
            A DLV  ++   GD F I+VA YPE HP+          +S Q+DL+ LK K+DAGA+  ITQ F+D + +L+F + C   GI   IVPGI+P++N+K   +       ++P  +T   + + ++ E  K  G  +  +M K +   G+K  H YTLN  + + AI   LG+
Sbjct:  132 AADLVSLLKEV-GD-FDISVAAYPEVHPEA---------KSAQADLINLKHKIDAGANRAITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFDGLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGV 292