CV884958

BLAST of CV884958 vs. ExPASy Swiss-Prot
Match: MTHR_CAEEL (Probable methylenetetrahydrofolate reductase OS=Caenorhabditis elegans GN=C06A8.1 PE=1 SV=2)

HSP 1 Score: 196.823 bits (499), Expect = 1.213e-49
Identity = 113/272 (41.54%), Postives = 163/272 (59.93%), Query Frame = 3

Query:    3 DITWGAGGSTADL-----TLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHG-IKTVHLYTLNMEKSALAILLNLGLIEESQISRSLPWR 800
            D+TW  G   A++     +  IA  M +   V+TM+H+TC           L+  K+ G++++LALRGD P G +  ++    F  ALD+++ IR  YG+YF I  AGYP GHP            SY++DL+YLK K DAGA+ +ITQLF++ + F KFV DCR+IGIT PI+PGIMPI  Y+   R+    + +IP  I   LEPIK +++AV+ YG     EMC+++L +G   ++HLYT+N E S   IL +LGL  + +  R  PW+
Sbjct:  105 DMTWHMGSDPANVDKVTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGLRSILALRGDLPPGTE--LEDTHQFR-ALDMIRWIREEYGNYFSIGCAGYPLGHPQA---------PSYKADLMYLKAKCDAGANFVITQLFFEAETFEKFVRDCREIGITQPIIPGIMPIMGYESIKRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGTAPSIHLYTMNREGSIREILKSLGL-WKLEGDRVFPWK 363          

BLAST of CV884958 vs. ExPASy Swiss-Prot
Match: MTHR2_SCHPO (Methylenetetrahydrofolate reductase 2 OS=Schizosaccharomyces pombe GN=met11 PE=2 SV=2)

HSP 1 Score: 194.897 bits (494), Expect = 4.609e-49
Identity = 109/263 (41.44%), Postives = 153/263 (58.17%), Query Frame = 3

Query:    6 ITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITC----PIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKIL------AHGIKTVHLYTLNMEKSALAILLNLGLI 764
            +TWG  GSTA++++ +A  ++    +   +HLTCTN+    ID AL+T K  GI+N+LALRGDPP   D +      F  A+DLV++IR  YGDYF I VA YPEGH D+  P+    ++    D+ +L +KV+AGAD IITQ+FY+ + F+KF N  R          PI+P IMPI +Y    RMT  C   +P+ +   L   K ++EA+K  G+    +M KKI+       HG    H  TLN+E+S   IL N GL+
Sbjct:   51 VTWGTAGSTAEVSIYLAKMLEQHHKIPACLHLTCTNVDKAIIDKALETAKEYGIRNILALRGDPPLNSDHWEGKVSEFEHAVDLVRYIREKYGDYFCIGVAAYPEGHVDSNVPE---LSKDPLRDIPFLIEKVEAGADFIITQIFYEPEAFIKFENFVRNHSSNALRNIPIIPAIMPIQSYGSLKRMTRLCGCSVPSSLMQRLNAAKPDDEAIKNIGVEHIVDMIKKIMDNVQGRVHGF---HFCTLNLERSVALILKNSGLL 307          

BLAST of CV884958 vs. ExPASy Swiss-Prot
Match: MTHR1_YEAST (Methylenetetrahydrofolate reductase 1 OS=Saccharomyces cerevisiae GN=MET12 PE=1 SV=2)

HSP 1 Score: 186.422 bits (472), Expect = 1.639e-46
Identity = 108/254 (42.52%), Postives = 152/254 (59.84%), Query Frame = 3

Query:    6 ITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQD--KFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQ-IGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEP-IKDNEEAVKAYGIHLGAEMCKKI---LAHGIKTVHLYTLNMEKSALAIL 746
            +TWGAGG+TA+ TL +A+  Q T+ +   MHLTCTN     ID AL    + GI+N+LALRGDPP G+D       +  F  A+DLV++I+ +YGD F + VA YPEGH +    +     +    DL+YLK+KV+AGAD +ITQLFYD + FL F    R+ I    P+ PG+MPIN+Y  F R        IP  I +   P I+ ++ AVK+ G+ +  E+ ++I    +  IK  H YTLN+EK+   I+
Sbjct:   48 VTWGAGGTTAEKTLTLASLAQQTLNIPVCMHLTCTNTEKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDSQSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCE---GEAEGHEQDPLKDLVYLKEKVEAGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPPAILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIV 298          

BLAST of CV884958 vs. ExPASy Swiss-Prot
Match: METF_AQUAE (5,10-methylenetetrahydrofolate reductase OS=Aquifex aeolicus GN=metF PE=3 SV=1)

HSP 1 Score: 184.496 bits (467), Expect = 6.229e-46
Identity = 95/246 (38.62%), Postives = 137/246 (55.69%), Query Frame = 3

Query:    6 ITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTVHLYTLNMEKSALAI 743
            +T+GAGGST D T +I  ++     +  M HLTC     E++   LQ  K+ GI+N+LALRGD P  +  +   +G    A +LV+ IR  +GD+F I VA YPEGHP++          + + ++ Y K+KV+AGAD  ITQ+F+  D + +FV  C+  GI   I+PGIMPI N+K   +    C   IP  +   LE ++D  E VK  GI      C  ++ HG+  +H YTLN   + L I
Sbjct:   47 VTYGAGGSTRDRTRNIVQKIHEETNLTVMAHLTCIAHTREELIDILQDYKNIGIENILALRGDVPRDKPDWRPPKGACKYAKELVELIRKEFGDWFSIGVASYPEGHPES---------PNLEWEVKYFKEKVEAGADFSITQMFFVNDYYYRFVEMCKNAGIDISIIPGIMPITNFKQIRKFASLCGATIPQSLIEKLEKVEDKPEEVKKIGIEFAINQCLDLIEHGVPGLHFYTLNKSDATLKI 283          

BLAST of CV884958 vs. ExPASy Swiss-Prot
Match: METF_SHIFL (5,10-methylenetetrahydrofolate reductase OS=Shigella flexneri GN=metF PE=3 SV=1)

HSP 1 Score: 143.665 bits (361), Expect = 1.219e-33
Identity = 85/252 (33.73%), Postives = 133/252 (52.78%), Query Frame = 3

Query:    6 ITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTVHLYTLNMEKSALAILLNLGL 761
            +T+GA     D T  I   +++   +E   HLTC +   +++    +   +NGI++++ALRGD P G  K          A DLV  ++      F I+VA YPE HP+          +S Q+DLL LK+KVDAGA+  ITQ F+D + +L+F + C   GI   I+PGI+P++N+K   +       +IPA +    + + D+ E  K  G ++  +M K +   G+K  H YTLN  + + AI   LG+
Sbjct:   58 VTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGDLPPGSGKPEMY------ASDLVTLLKEVAD--FDISVAAYPEVHPEA---------KSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGV 292          

BLAST of CV884958 vs. ExPASy Swiss-Prot
Match: METF_ECOLI (5,10-methylenetetrahydrofolate reductase OS=Escherichia coli (strain K12) GN=metF PE=1 SV=1)

HSP 1 Score: 143.665 bits (361), Expect = 1.219e-33
Identity = 85/252 (33.73%), Postives = 133/252 (52.78%), Query Frame = 3

Query:    6 ITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTVHLYTLNMEKSALAILLNLGL 761
            +T+GA     D T  I   +++   +E   HLTC +   +++    +   +NGI++++ALRGD P G  K          A DLV  ++      F I+VA YPE HP+          +S Q+DLL LK+KVDAGA+  ITQ F+D + +L+F + C   GI   I+PGI+P++N+K   +       +IPA +    + + D+ E  K  G ++  +M K +   G+K  H YTLN  + + AI   LG+
Sbjct:   58 VTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGDLPPGSGKPEMY------ASDLVTLLKEVAD--FDISVAAYPEVHPEA---------KSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGV 292          

BLAST of CV884958 vs. ExPASy Swiss-Prot
Match: METF_SALTY (5,10-methylenetetrahydrofolate reductase OS=Salmonella typhimurium GN=metF PE=3 SV=2)

HSP 1 Score: 140.969 bits (354), Expect = 7.898e-33
Identity = 83/252 (32.94%), Postives = 133/252 (52.78%), Query Frame = 3

Query:    6 ITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTVHLYTLNMEKSALAILLNLGL 761
            +T+GA     D T  +   ++    +E   HLTC +   +++    +   +NGI++++ALRGD P G  K          A DLV  ++      F I+VA YPE HP+          +S Q+DLL LK+KVDAGA+  ITQ F+D + +L+F + C   GI   I+PGI+P++N+K   +       +IP+ ++   E + ++ E  K  G ++  +M K +   G+K  H YTLN  + + AI   LG+
Sbjct:   58 VTYGANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTIARDYWNNGIRHIVALRGDLPPGSGKPEMY------AADLVGLLKEVAD--FDISVAAYPEVHPEA---------KSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPSWMSLMFEGLDNDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGV 292          

BLAST of CV884958 vs. ExPASy Swiss-Prot
Match: METF_NEIMB (5,10-methylenetetrahydrofolate reductase OS=Neisseria meningitidis serogroup B GN=metF PE=1 SV=1)

HSP 1 Score: 140.969 bits (354), Expect = 7.898e-33
Identity = 85/252 (33.73%), Postives = 132/252 (52.38%), Query Frame = 3

Query:    6 ITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTVHLYTLNMEKSALAILLNLGL 761
            +T+GA     D T  I  R++    +E   HLT  +   +++    +    +GI+ ++ALRGD P G +K          A DLVK +RS     F I+VA YPE HP+          +S Q+DL+ LK+K+DAGA+ +ITQ F+D + +L+F + C  +GI   IVPGI+P+ N+K   +M      KIP+ ++   E + D++         +  +M K +   G+K  H YTLN  +   AI   LG+
Sbjct:   56 VTYGANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEPAGYEKKPFY------AEDLVKLLRSVAD--FDISVAAYPEVHPEA---------KSAQADLINLKRKIDAGANHVITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGV 290          

BLAST of CV884958 vs. ExPASy Swiss-Prot
Match: METF_HAEIN (5,10-methylenetetrahydrofolate reductase OS=Haemophilus influenzae GN=metF PE=3 SV=1)

HSP 1 Score: 139.428 bits (350), Expect = 2.298e-32
Identity = 85/252 (33.73%), Postives = 129/252 (51.19%), Query Frame = 3

Query:    6 ITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTVHLYTLNMEKSALAILLNLGL 761
            +T+GA     D T  I   ++    +E   HLT  +   E++    +    +GI+ ++ALRGD P G  K          A DLV+ +RS     F I+VA YPE HP+          +S Q+DL+ LK+K+DAGA+ +ITQ F+D + +L+F + C  IGI   IVPGI+P+ N+K   +M  F   KIPA +  A + + ++          +  +M K +   G+   H YTLN  +   AI   LG+
Sbjct:   56 VTYGANSGERDRTHGIVKAIKQETGLEAAPHLTGIDATPEELKQIARDYWDSGIRRIVALRGDEPKGYAKKPFY------ASDLVELLRSVAD--FDISVAAYPEVHPEA---------KSAQADLINLKRKIDAGANHVITQFFFDIENYLRFRDRCASIGIDTEIVPGILPVTNFKQLQKMASFTNVKIPAWLVKAYDGLDNDPTTRNLVAASVAMDMVKILSREGVNDFHFYTLNRSELTYAICHMLGV 290          

BLAST of CV884958 vs. ExPASy Swiss-Prot
Match: METF_PECCC (5,10-methylenetetrahydrofolate reductase OS=Pectobacterium carotovorum subsp. carotovorum GN=metF PE=3 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 5.119e-32
Identity = 85/254 (33.46%), Postives = 132/254 (51.97%), Query Frame = 3

Query:    6 ITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIQGGFA--CALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTVHLYTLNMEKSALAILLNLGL 761
            +T+GA     D T  I   ++    +E   HLTC +   E++    Q    +GI++++ALRGD P         +GG     A DLV  ++   GD F I+VA YPE HP+          +S Q+DL+ LK K+DAGA+  ITQ F+D + +L+F + C   GI   IVPGI+P++N+K   +       ++P  +T   + + ++ E  K  G  +  +M K +   G+K  H YTLN  + + AI   LG+
Sbjct:   58 VTYGANSGERDRTHSIIKTIKERTGLEAAPHLTCIDASREQLREIAQDYWESGIRHIVALRGDLPQ--------EGGKPDMYAADLVSLLKEV-GD-FDISVAAYPEVHPEA---------KSAQADLINLKHKIDAGANRAITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQKFATMTNVRVPNWMTTMFDGLDNDPETRKMVGASIAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGV 292