CV884403

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: DHB5_MOUSE (Estradiol 17 beta-dehydrogenase 5 OS=Mus musculus GN=Akr1c6 PE=1 SV=1)

HSP 1 Score: 192.586 bits (488), Expect = 2.450e-48
Identity = 107/274 (39.05%), Postives = 172/274 (62.77%), Query Frame = 1

Query:   76 MPVIGLGS-AVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVSLDYNGV-----WEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ----VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            +P++G G+ A   + +S    A   +I  G+RH D+AS+Y  E+ +G AI   +  G V  RE++F T+K+WC+    +LV   L++SLK LQ++YVDLYLIH+PM+ KP E   N +P+++   L Y+ V     WEAME+C+  GL KSIGVSNF+ +++E IL    +   P  NQVE +P   Q KL++FC+SK I++ A+S LG+       +Q    +++N  L  +A  + +T A + LR+ +++G     KSF+++R+KEN+++F+
Sbjct:   16 IPILGFGTYAPQEVPKSKATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKIADGTV-KREDIFYTSKVWCTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMKPGE---NYLPKDENGKLIYDAVDICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILKKPGLKYKPVCNQVECHPYLNQGKLLDFCRSKDIVLVAYSALGSHREKQWVDQSSPVLLDNPVLGSMAKKYNRTPALIALRYQLQRGVVVLAKSFSEKRIKENMQVFE 285          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AK1C2_HUMAN (Aldo-keto reductase family 1 member C2 OS=Homo sapiens GN=AKR1C2 PE=1 SV=3)

HSP 1 Score: 192.2 bits (487), Expect = 3.199e-48
Identity = 108/274 (39.42%), Postives = 172/274 (62.77%), Query Frame = 1

Query:   76 MPVIGLGS-AVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSS-W---GTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            MPV+G G+ A   + +S    AV  +I+ G+ H D+A +Y  E  +G AI   +  G V  RE++F T+KLW +    +LV PAL++SLK LQ++YVDLYLIH+P+S KP E++   IP+++       ++D    WEAME+C+  GL KSIGVSNF+ + +E IL    +   P  NQVE +P + QRKL++FCKSK I++ A+S LG+     W    +  ++ +  L  +A  H +T A + LR+ +++G     KS+N++R+++N+++F+
Sbjct:   16 MPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSV-KREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEV---IPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFE 285          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: ALDR_HUMAN (Aldose reductase OS=Homo sapiens GN=AKR1B1 PE=1 SV=3)

HSP 1 Score: 191.815 bits (486), Expect = 4.178e-48
Identity = 109/270 (40.37%), Postives = 160/270 (59.26%), Query Frame = 1

Query:   73 KMPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVSLDYN--GVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ---VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            KMP++GLG+         +  AV  +I +GYRH D A +Y  E  +G AI E L+  +V  REELFI +KLWC+   + LV  A +K+L  L+++Y+DLYLIHWP   KP ++        ++V  D N    W AMEE    GL K+IG+SNF+  ++E IL    +   P VNQ+E +P   Q KL+++C+SK I+VTA+SPLG+    W   +   ++ +  +K IAA H KT AQV +R+ +++      KS   ER+ EN ++FD
Sbjct:   12 KMPILGLGTWKS--PPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVV-KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFD 278          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AKCL2_MOUSE (1,5-anhydro-D-fructose reductase OS=Mus musculus GN=Akr1e2 PE=1 SV=1)

HSP 1 Score: 191.43 bits (485), Expect = 5.457e-48
Identity = 109/275 (39.64%), Postives = 164/275 (59.64%), Query Frame = 1

Query:   76 MPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVSLDYNG-----------VWEAMEECQRHGLTKSIGVSNFSPKKIETIL--AFATIPPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            +P +GLG+   +  E  +  AV  +I LGYRHFD A LY  E  +G  I+E +K G+V  RE+LF+ +KLWC+   + LV  A   +L+ L ++Y+DLYLIHWPM  KP EK   DIP      LD NG            WEAME+    GL K++GVSNF+ +++E +L      + P  NQ+E +P   Q+KL++FC  +++ VTA+ PLG  G   G   +M++  +++IA  HGK+ AQ+ +R+ I++      KS    R++EN+++FD
Sbjct:    4 IPTVGLGTWKASPGE--VTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIKEGVV-KREDLFVVSKLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFKPGEK---DIP------LDRNGKVIPSHTSFLDTWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPYLNQKKLIDFCHKRNVSVTAYRPLGGSG---GGFHLMDDTVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVTPSRIRENIQVFD 263          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AK1C4_MACFU (Aldo-keto reductase family 1 member C4 OS=Macaca fuscata fuscata GN=AKR1C4 PE=1 SV=1)

HSP 1 Score: 190.274 bits (482), Expect = 1.216e-47
Identity = 107/274 (39.05%), Postives = 166/274 (60.58%), Query Frame = 1

Query:   76 MPVIGLGS-AVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ----VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            MPV+G GS A   +  + +      +I+ G+RH D+A LY  E  +G AI   +  G V  RE++F T+KLWC+     LV PAL+ SLK LQ++YVDLYLIH+PM+ KP E     +P+++       ++D   +WEAME+C+  GL KSIGVSNF+ +++E IL    +   P  NQVE +P   Q KL++FCKSK I++ A S LG        +Q    ++ +  L  +A  H ++ A + LR+ +++G     KS+N++R++EN+++F+
Sbjct:   16 MPVLGFGSYAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSV-KREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALKPGE---TPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPVLCALAKKHKRSPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFE 285          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: ALDR_RABIT (Aldose reductase OS=Oryctolagus cuniculus GN=AKR1B1 PE=2 SV=3)

HSP 1 Score: 189.889 bits (481), Expect = 1.588e-47
Identity = 112/274 (40.88%), Postives = 157/274 (57.30%), Query Frame = 1

Query:   73 KMPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAK------PSEKLRNDIPEEDLVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ---VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            KMP++GLG+         +  AV  +I LGYRH D A +Y  E  +G A+ E LK  +V  REELFI +KLWC+   + LV  A +K+L  L+++Y+DLYLIHWP   K      P +   N IP +     D+   WEAME     GL KSIGVSNF+  +IE IL    +   P VNQ+E +P   Q KL+++C SK I+VTA+SPLG+    W   +   ++ +  +K IA  H KT AQV +R+ +++      KS    R+ EN ++FD
Sbjct:   12 KMPILGLGTWKS--PPGQVTEAVKTAIDLGYRHIDCAHVYQNENEVGVALQEKLKEQVV-KREELFIVSKLWCTSHDKSLVKGACQKTLNDLKLDYLDLYLIHWPTGFKHGSEYFPLDAAGNVIPSD----TDFLDTWEAMEGLVDEGLVKSIGVSNFNHLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIQYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIADKHKKTTAQVLIRFPMQRNLVVIPKSVTPARIAENFQVFD 278          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: ALDR_RAT (Aldose reductase OS=Rattus norvegicus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 189.504 bits (480), Expect = 2.074e-47
Identity = 109/274 (39.78%), Postives = 159/274 (58.03%), Query Frame = 1

Query:   73 KMPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPS------EKLRNDIPEEDLVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ---VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            KMP +GLG+         +  AV  +I +GYRH D A +Y  E+ +G A+ E LK  +V  R++LFI +KLWC+   + +V  A +K+L  LQ++Y+DLYLIHWP   KP       +   N IP +     D+   W AME+    GL K+IGVSNF+P +IE IL    +   P VNQ+E +P   Q KL+E+C  K I+VTA+SPLG+    W   +   ++ +  +K+IAA + KT AQV +R+ I++      KS    R+ EN ++FD
Sbjct:   12 KMPTLGLGTWKS--PPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVV-KRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSD----TDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFD 278          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AK1CN_HORSE (Aldo-keto reductase family 1 member C23 OS=Equus caballus GN=AKR1C23 PE=1 SV=1)

HSP 1 Score: 189.119 bits (479), Expect = 2.708e-47
Identity = 105/269 (39.03%), Postives = 165/269 (61.34%), Query Frame = 1

Query:   85 IGLGSAVDN-IDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSW---GTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIF 858
            +G G+   N + +S    A   +I  G+RH D A LY  E+ +G AI   ++ G V  RE++F T+KLW +     LV PAL+KSLK LQ++YVDLY+IH+P++ KP E+    +P+++       ++D    WEAME+C+  GLTKSIGVSNF+ +++E IL    +   P  NQVE +P   Q KL++FCKSK I++ A+S LG+    W    +  ++ +  L  +A  + +T A + LR+ +++G     KS+N++R+KEN++ F
Sbjct:   19 LGFGTYAPNEVPKSKAVEATKSAIDAGFRHIDCAHLYDNEKEVGLAIRSKIQDGTV-KREDIFCTSKLWATSLRLQLVRPALEKSLKNLQLDYVDLYIIHFPVAVKPGEE---HLPQDEQGRMIFDTVDLCATWEAMEKCKDAGLTKSIGVSNFNRRQLEMILNKPGLKHKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAYSALGSQREHWIDQSSPVLLEDPVLCAMAKKYKRTPALIALRYQLQRGVVVLAKSYNEKRIKENVQAF 283          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AK1C4_MACFA (Aldo-keto reductase family 1 member C4 OS=Macaca fascicularis GN=AKR1C4 PE=1 SV=1)

HSP 1 Score: 189.119 bits (479), Expect = 2.708e-47
Identity = 106/274 (38.69%), Postives = 166/274 (60.58%), Query Frame = 1

Query:   76 MPVIGLGS-AVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ----VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            MPV+G G+ A   +  + +      +I+ G+RH D+A LY  E  +G AI   +  G V  RE++F T+KLWC+     LV PAL+ SLK LQ++YVDLYLIH+PM+ KP E     +P+++       ++D   +WEAME+C+  GL KSIGVSNF+ +++E IL    +   P  NQVE +P   Q KL++FCKSK I++ A S LG        +Q    ++ +  L  +A  H ++ A + LR+ +++G     KS+N++R++EN+++F+
Sbjct:   16 MPVLGFGTYAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSV-KREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALKPGE---TPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPVLCALAKKHKRSPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFE 285          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: ALDR_BOVIN (Aldose reductase OS=Bos taurus GN=AKR1B1 PE=1 SV=1)

HSP 1 Score: 188.734 bits (478), Expect = 3.537e-47
Identity = 110/274 (40.15%), Postives = 158/274 (57.66%), Query Frame = 1

Query:   73 KMPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKL------RNDIPEEDLVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ---VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            KMP++GLG+         +  AV  +I LGYRH D A +Y  E  +G A+   L+  +V  RE+LFI +KLWC+   +DLV  A +K+L  L+++Y+DLYLIHWP   KP +         N IP E     D+   W AMEE    GL K+IGVSNF+  ++E IL    +   P VNQ+E +P   Q KL+++C SK I+VTA+SPLG+    W   +   ++ +  +K IA  + KT AQV +R+ I++      KS   ER+ EN ++FD
Sbjct:   11 KMPILGLGTWKS--PPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQAKLQEQVV-KREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKDFFPLDEDGNVIPSEK----DFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIECHPYLTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKYNKTTAQVLIRFPIQRNLIVIPKSVTPERIAENFQVFD 277