CV884403

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AK1BA_HUMAN (Aldo-keto reductase family 1 member B10 OS=Homo sapiens GN=AKR1B10 PE=1 SV=1)

HSP 1 Score: 186.422 bits (472), Expect = 1.756e-46
Identity = 110/273 (40.29%), Postives = 160/273 (58.61%), Query Frame = 1

Query:   73 KMPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVS-----LDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ---VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            KMP++GLG+    + +  +K AV  +I  GYRH D A +Y  E  +GEAI E ++   V  RE+LFI +KLW +   R LV  A +K+LK L++ Y+D+YLIHWP   K  + L    P++D  +       +   WEAMEE    GL K++GVSNFS  +IE +L    +   P  NQVE +P   Q KL+++C SK I VTA+SPLG+    W   +   ++ +  +K+IAA H KT AQV +R+ I++      KS    R+ EN+++FD
Sbjct:   12 KMPIVGLGTWKSPLGK--VKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAV-KREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL---FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFD 278          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AK1A1_PONAB (Alcohol dehydrogenase [NADP+] OS=Pongo abelii GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 186.422 bits (472), Expect = 1.756e-46
Identity = 99/272 (36.40%), Postives = 163/272 (59.93%), Query Frame = 1

Query:   70 RKMPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATIPPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ---VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            +KMP+IGLG+     +   +K+AV  ++ +GYRH D A++YG E  +GEA+ E +  G    REELF+T+KLW +  H + V PAL+K+L  LQ+EY+DLYL+HWP +    E+  N  P+         S  Y   W+A+E     GL +++G+SNF+ ++I+ IL+ A++ P V QVE +P   Q +L+  C+++ + VTA+SPLG+   +W       ++    +  +A  +G + AQ+ LRW +++      KS    R+ +N+++FD
Sbjct:   12 QKMPLIGLGTWKS--EPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALQKTLADLQLEYLDLYLMHWPYA---FERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVRALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLAVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGGSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFD 278          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: PE2R_RABIT (Prostaglandin-E(2) 9-reductase OS=Oryctolagus cuniculus GN=AKR1C5 PE=1 SV=1)

HSP 1 Score: 186.037 bits (471), Expect = 2.293e-46
Identity = 107/284 (37.68%), Postives = 173/284 (60.92%), Query Frame = 1

Query:   46 KLSSASGHRKMPVIGLGS-AVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ----VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            +++ + GH  +PV+G G+ A + + +S    A   +I  G+RH D+A  Y  E+ +G AI   +  G V  RE++F T+KLWC+    +LV P+L+ SLK LQ++YVDLY+IH+P + KP  ++   IP ++       ++D    WEAME+C+  GL KSIGVSNF+ +++E IL    +   P  NQVE +P   Q KL+EFCKSK I++ A+S LG+       +Q    ++ +  +  +A  H +T A + LR+ +++G     KSF ++R+KEN+++F+
Sbjct:    7 RVALSDGHF-IPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRSKIADGTV-KREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPGVEI---IPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYLNQGKLLEFCKSKGIVLVAYSALGSHREPEWVDQSAPVLLEDPLIGALAKKHQQTPALIALRYQLQRGIVVLAKSFTEKRIKENIQVFE 285          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AKCL2_RAT (1,5-anhydro-D-fructose reductase OS=Rattus norvegicus GN=Akr1e2 PE=2 SV=1)

HSP 1 Score: 186.037 bits (471), Expect = 2.293e-46
Identity = 107/270 (39.63%), Postives = 165/270 (61.11%), Query Frame = 1

Query:   73 KMPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVSL-----DYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETIL--AFATIPPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            ++P +GLG+   +  E  +  AV  +I LGYRHFD A LY  E  +G  I E +K G+V  R+ELFI +KLWC+   + LV  A   +L+ L ++Y+DLYLIHWPM  KP +K   DIP +    +      +   WEAME+    GL K+IGVSNF+ ++++ +L      I P  NQ+E +P   Q+ L++FC  +++ VTA+ PLG  GS  G + +M++  +++IA  HGK+ AQ+ +R+ I++      KS N  R++EN+++FD
Sbjct:    3 QIPTVGLGTWKASPGE--VTDAVKVAINLGYRHFDCAYLYHNESEVGMGIKEKIKEGVV-KRDELFIVSKLWCTYHKQSLVKTACINTLEALNLDYLDLYLIHWPMGFKPGDK---DIPLDRSGKVIPSHTSFLDTWEAMEDLVIEGLVKNIGVSNFNHEQLDRLLNKPGLRIKPITNQIECHPYLNQKSLIDFCHGRNVSVTAYRPLG--GSRDGVH-LMDDIVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVNPSRIRENIQVFD 263          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AKC1H_RAT (Aldo-keto reductase family 1 member C18 OS=Rattus norvegicus GN=Akr1c18 PE=1 SV=1)

HSP 1 Score: 186.037 bits (471), Expect = 2.293e-46
Identity = 107/285 (37.54%), Postives = 176/285 (61.75%), Query Frame = 1

Query:   46 KLSSASGHRKMPVIGLGSAV--DNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATIP--PTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ----VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            K+    GH  +PV+G G+    +N+ + +M+S  + +I +G+RH D + LY  E  +G+AI   ++ G V  RE++F T+KLW +    +LV P+L+ SL+ L ++YVDLYLIH+P+S KP ++L   +P+++     L ++D    WEAME+C+  GL KSIGVSNF+ +++E IL    +   P  NQVE +    Q KL+ +CK   I++ A+  LG     +  N+    ++++  L  +A  + +T A + LR+ +E+G    VKSFN+ER++ENL++FD
Sbjct:    7 KMELNDGH-SIPVLGFGTYATEENLRKKSMESTKI-AIDVGFRHIDCSHLYQNEEEIGQAIVSKIEDGTV-KREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGDEL---LPQDEHGNLILDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDDPILCTMAKKYKRTPALIALRYQLERGIVTLVKSFNEERIRENLQVFD 285          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AK1C3_PONAB (Aldo-keto reductase family 1 member C3 homolog OS=Pongo abelii GN=AKR1C3 PE=2 SV=1)

HSP 1 Score: 186.037 bits (471), Expect = 2.293e-46
Identity = 107/271 (39.48%), Postives = 163/271 (60.15%), Query Frame = 1

Query:   76 MPVIGLGS-AVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLV--SLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAV-GSSW---GTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            MPV+G G+ A   +  S        +I+ G+RH D+A LY  E  +G AI   +  G V  RE++F T+KLW +    +LV PAL+ SLK  Q++YVDLYLIH PMS KP E+L        ++   +D    WEAMEEC+  GL KSIGVSNF+ +++E IL    +   P  NQVE +P + + KL++FCKSK I++ A+S LG+     W    +  ++ +  L  +A  H +T A + LR+ +++G     KS+N++R++EN+++F+
Sbjct:   16 MPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSV-KREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEECKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFE 285          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AK1C4_HUMAN (Aldo-keto reductase family 1 member C4 OS=Homo sapiens GN=AKR1C4 PE=1 SV=2)

HSP 1 Score: 185.267 bits (469), Expect = 3.911e-46
Identity = 104/274 (37.96%), Postives = 164/274 (59.85%), Query Frame = 1

Query:   76 MPVIGLGS-AVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSS-W---GTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            MPV+G G+ A   +  +        +I+ G+RH D+A LY  E  +G AI   +  G V  RE++F T+KLWC+     +V PAL+ SLK LQ++YVDLYL+H+PM+ KP E     +P+++       ++D +  WE ME+C+  GL KSIGVSNF+ +++E IL    +   P  NQVE +P   Q KL++FCKSK I++ A S LG      W    +  ++ +  L  +A  H +T A + LR+ +++G     KS+N++R++EN+++F+
Sbjct:   16 MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSV-KREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE---TPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFE 285          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: ALD1_MOUSE (Aldose reductase-related protein 1 OS=Mus musculus GN=Akr1b7 PE=2 SV=4)

HSP 1 Score: 184.882 bits (468), Expect = 5.108e-46
Identity = 106/273 (38.83%), Postives = 161/273 (58.97%), Query Frame = 1

Query:   73 KMPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ---VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            KMP++GLG+   +  +  +K AV  +I  GYRH D A +Y  E  +GEAI E +K   V  RE+LFI +KLW +   + LV  A + +L  L+++Y+DLYL+HWP   +    L   +P+++     L    +   WEAMEE    GL K++G+SNF+  +IE +L    +   P  NQ+E +P   Q KL+++C+SK I VTA+SPLG+    +   +   VM    +K+IAA H KTVAQV +R+ +++      KS    R++ENL++FD
Sbjct:   12 KMPLVGLGTWKSSPGQ--VKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIKENAV-KREDLFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQAGNAL---LPKDNKGKVLLSKSTFLDAWEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEKLIQYCQSKGIAVTAYSPLGSPDRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRFHVQRNVVVIPKSVTPSRIQENLQVFD 278          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AK1C3_HUMAN (Aldo-keto reductase family 1 member C3 OS=Homo sapiens GN=AKR1C3 PE=1 SV=3)

HSP 1 Score: 183.341 bits (464), Expect = 1.486e-45
Identity = 105/271 (38.75%), Postives = 163/271 (60.15%), Query Frame = 1

Query:   76 MPVIGLGS-AVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLV--SLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAV-GSSW---GTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            MPV+G G+ A   +  S        +I+ G+RH D+A LY  E  +G AI   +  G V  RE++F T+KLW +    +LV PAL+ SLK  Q++YVDLYLIH PMS KP E+L        ++   +D    WEAME+C+  GL KSIGVSNF+ +++E IL    +   P  NQVE +P + + KL++FCKSK I++ A+S LG+     W    +  ++ +  L  +A  H +T A + LR+ +++G     KS+N++R+++N+++F+
Sbjct:   16 MPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSV-KREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFE 285          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AK1D1_MOUSE (3-oxo-5-beta-steroid 4-dehydrogenase OS=Mus musculus GN=Akr1d1 PE=2 SV=1)

HSP 1 Score: 182.956 bits (463), Expect = 1.941e-45
Identity = 112/294 (38.10%), Postives = 171/294 (58.16%), Query Frame = 1

Query:   16 MNVSINVPEVKLSSASGHRKMPVIGLGSAVDNIDESAMKS-AVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVSLDYN-----GVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAV-GSSW---GTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            MN+S    ++ LS  +    +P+IGLG+  D          AV  +I  GYRH D A +Y  E  +GEAI E +  G V  REE+F   KLW ++    +V+PAL+++LK L+++Y+DLY+I  PM+ KP +++    P ++   + Y+       WEA+E C+  GL KS+GVSNF+ +++E IL    +   P  NQVE +P + Q KL++FC+   I++ A SPLG     SW    +  ++N+E L  +   + KT AQ+ LR+ I++G     KSF  ER+KEN +IFD
Sbjct:    1 MNLSAAHHQISLSDGNN---IPLIGLGTYSDPRPVPGKTYVAVKTAIDEGYRHIDGAYVYHNEHEVGEAIREKIAEGKV-KREEIFYCGKLWNTEHVPSMVLPALERTLKALKLDYIDLYIIELPMAFKPGKEI---YPRDENGRIIYDKTNLCATWEALEACKDAGLVKSLGVSNFNRRQLELILNKPGLKYKPVTNQVECHPYFTQTKLLKFCQQHDIVIVAHSPLGTCRNPSWVNVSSPPLLNDELLTSLGKKYNKTQAQIVLRFNIQRGIVVIPKSFTPERIKENFQIFD 287