CV884403

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AK1D1_HUMAN (3-oxo-5-beta-steroid 4-dehydrogenase OS=Homo sapiens GN=AKR1D1 PE=1 SV=1)

HSP 1 Score: 182.956 bits (463), Expect = 1.941e-45
Identity = 110/289 (38.06%), Postives = 168/289 (58.13%), Query Frame = 1

Query:   55 SASGHR-------KMPVIGLG--SAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVSLDYN-----GVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTN----QVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            SA+ HR        +P+IGLG  S   +  + A  ++V  +I  GYRH D A +Y  E  +GEAI E +  G V  RE++F   KLW ++   ++V P L+++L+ LQ++YVDLY+I  PM+ KP +++    P ++     Y+       WEAME C+  GL KS+GVSNF+ +++E IL    +   P  NQVE +P + Q KL++FC+   I++TA+SPLG   +    N     ++ +  L  +   + KT AQ+ LR+ I++G     KSFN ER+KEN +IFD
Sbjct:    4 SAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVR-REDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEI---YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFD 288          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AKCL2_HUMAN (1,5-anhydro-D-fructose reductase OS=Homo sapiens GN=AKR1E2 PE=1 SV=2)

HSP 1 Score: 182.185 bits (461), Expect = 3.311e-45
Identity = 111/285 (38.95%), Postives = 159/285 (55.79%), Query Frame = 1

Query:   76 MPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKP----------------SEKLRNDIP--EEDLV---SLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETIL--AFATIPPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            +P +GL S         +  AV E+I  GYRHFD A  Y  ER +G  I   +K G V  RE+LFI TKLWC+   + LV  A +KSLK L++ Y+DLYLIHWPM  KP                S     D+P  E ++V     D+   WEAME+    GL K+IGVSNF+ +++E +L        P  NQ+E +P   Q+ L+ FC+S+ + VTA+ PLG  GS  G + +++N  +K+IA  HGK+ AQ+ +R+ I++       S     +KEN+++FD
Sbjct:    4 IPAVGLSSW--KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR-REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG--GSCEGVD-LIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFD 282          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: ALD2_MOUSE (Aldose reductase-related protein 2 OS=Mus musculus GN=Akr1b8 PE=1 SV=2)

HSP 1 Score: 179.104 bits (453), Expect = 2.803e-44
Identity = 106/273 (38.83%), Postives = 159/273 (58.24%), Query Frame = 1

Query:   73 KMPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ---VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            KMP++GLG+     ++  +K AV  +I  GYRH D A  Y  E  +GEAI E +K   V  RE+LFI +KLW +   + L+  A +K+L  L+++Y+DLYLIHWP   +P ++L    P++D          +   WE MEE    GL K++GVSNF+  +IE +L    +   P  NQVE +P   Q KL+++C SK I VTA+SPLG+        +   ++ +  +K+IAA H KT AQV +R+ I++      KS    R++EN+++FD
Sbjct:   12 KMPIVGLGTWKSPPNQ--VKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEKAV-QREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKEL---FPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFD 278          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: ALRC_DICDI (Aldose reductase C OS=Dictyostelium discoideum GN=alrC PE=3 SV=1)

HSP 1 Score: 177.948 bits (450), Expect = 6.244e-44
Identity = 107/288 (37.15%), Postives = 160/288 (55.56%), Query Frame = 1

Query:   19 NVSINVPEVKLSSASGHRKMPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPS-------EKLRNDIPEEDLVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATIPPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            N + N    KL+  +   ++P IGLG+     +   +  A+  ++K GYRH D A+ YG E+ +G ++ E  K G +  RE++F T+KLW S  + +LVV    K+++ L I Y+DLYLIHWP++ + S       E LR+      +  +     W+ ME+    GL KSIGVSNF+ + +  +L +A I P VNQVE++P   Q KL E+C    I + A+SPLG      G     +N+ LK IA  + K+VA V  +W+ ++G  A  KS N  R+ EN  IFD
Sbjct:    9 NTNYNNNNFKLNDGN---QIPSIGLGTYYSE-NPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEGEI-KREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLGQ-----GKCDFFSNKILKSIAGKYKKSVANVIFKWLNQRGIAAIPKSGNHSRIIENFNIFD 286          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AKC1H_MOUSE (Aldo-keto reductase family 1 member C18 OS=Mus musculus GN=Akr1c18 PE=2 SV=2)

HSP 1 Score: 177.948 bits (450), Expect = 6.244e-44
Identity = 102/282 (36.17%), Postives = 171/282 (60.64%), Query Frame = 1

Query:   46 KLSSASGHRKMPVIGLGSAV--DNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLV--SLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ----VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            K+    GH  +PV+G G+    +++ + +M+S  + +I +G+ H D + LY  E  +G+AI   ++ G V  RE++F T+KLW +    +LV P+L+ SL+ L ++YVDLYLIH+P+S KP  +L       +L+  ++D    WEAME+C+  GL KSIGVSNF+ +++E IL    +   P  NQVE +    Q KL+ +CK   I++ A+  LG     +  N+    ++++  L  +A  + +T A + LR+ +++G  A  KSFN+ER++EN+++FD
Sbjct:    7 KIELNDGH-SIPVLGFGTYATEEHLKKKSMESTKI-AIDVGFCHIDCSHLYQNEEEIGQAILSKIEDGTV-KREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDDPVLCAMAKKYKRTPALIALRYQLDRGIVALAKSFNEERIRENMQVFD 285          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: AK1CL_RAT (Aldo-keto reductase family 1 member C21 OS=Rattus norvegicus GN=Akr1c21 PE=2 SV=1)

HSP 1 Score: 177.948 bits (450), Expect = 6.244e-44
Identity = 103/272 (37.87%), Postives = 163/272 (59.93%), Query Frame = 1

Query:   76 MPVIGLGSAVDN-IDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATI--PPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQ----VMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEI 855
            +PV+G G+A+ + + +S  K     +I  G+ HFD+A +Y TE  +GEAI E +  G    RE++F T+KLWC+  H +LV  +L+ SLK LQ++YVDLYLIH+PM+ KP ++   + P ++       ++D    WEAME+C+  GL KSIGVSNF+ +++E IL    +   P  NQVE +    Q KL++FCK+  II+ A+  LG    +   +Q    ++N   L  +A  + +T A + LR  +++G      S  +ER+KEN+++
Sbjct:   16 IPVLGFGTAMPSELPKSKAKEVTKIAIDAGFHHFDSAFVYNTEDHVGEAIREKIANG-TTRREDIFYTSKLWCTSLHPELVRSSLECSLKKLQLDYVDLYLIHFPMALKPGDE---NFPVDEHGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQVECHLYLNQMKLLDFCKTNGIILVAYGVLGTQRYNGWVDQNSPVLLNEPVLSSMAKKYNQTPALIALRHQLQRGIVVLNTSLKEERIKENMKL 283          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: GR_BACSU (Glyoxal reductase OS=Bacillus subtilis GN=yvgN PE=1 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 1.178e-42
Identity = 104/264 (39.39%), Postives = 148/264 (56.06%), Query Frame = 1

Query:   73 KMPVIGLGS-AVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATIPPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            +MP  GLG   V+N +E+    +V  +IK GYR  DTA++Y  E  +G  I E+       +REELFIT+K+W  D   +  + A +KSL+ LQ++Y+DLYLIHWP   K                  Y   W A+E+  + G  ++IGVSNF    +E +L  A I P VNQVE +P   Q++L ++CK + I + A+SPL          Q+++NE L QIA  H K+VAQV LRW ++ G     KS  + R+ EN +IFD
Sbjct:   16 EMPWFGLGVFKVENGNEAT--ESVKAAIKNGYRSIDTAAIYKNEEGVGIGIKES-----GVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPGKDK------------------YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKGQGIQLEAWSPL-------MQGQLLDNEVLTQIAEKHNKSVAQVILRWDLQHGVVTIPKSIKEHRIIENADIFD 247          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: DKGA_CORSC (2,5-diketo-D-gluconic acid reductase A OS=Corynebacterium sp. (strain ATCC 31090) GN=dkgA PE=1 SV=3)

HSP 1 Score: 173.711 bits (439), Expect = 1.178e-42
Identity = 102/278 (36.69%), Postives = 156/278 (56.12%), Query Frame = 1

Query:   28 INVPEVKLSSASGHRKMPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATIPPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIFD 861
            + VP + L+  +    +P +G G  V  +  +  + AV E++++GYRH DTA++YG E  +G AIA +   G+  +R++LFITTKLW      D    A+ +SL  L ++ VDLYL+HWP  A  +                Y   WE M E +  GLT+SIGVSN     +E I+A   + P VNQ+E++PA+QQR++ ++  +  + + ++ PLG      G   +   E +   AA HGKT AQ  LRW +++G     KS  +ERL+ENL++FD
Sbjct:    1 MTVPSIVLNDGNS---IPQLGYG--VFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAAS---GI--ARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAADN----------------YVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHPAYQQREITDWAAAHDVKIESWGPLGQ-----GKYDLFGAEPVTAAAAAHGKTPAQAVLRWHLQKGFVVFPKSVRRERLEENLDVFD 247          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: GCY_YEAST (Protein GCY OS=Saccharomyces cerevisiae GN=GCY1 PE=1 SV=1)

HSP 1 Score: 172.94 bits (437), Expect = 2.009e-42
Identity = 104/283 (36.75%), Postives = 159/283 (56.18%), Query Frame = 1

Query:   46 KLSSASGHRKMPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDI---PEE-------DLVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFA--TIPPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEIF 858
            K+ S +   ++P IGLG+      E+    AVL ++K GYRH DTA++Y  E  +G+AI ++        REE+F+TTKLWC+  H   V  AL +SLK L ++YVDLYL+HWP    P+     DI   P +       D+ + ++   WE M+E  + G TK++GVSNFS   ++ +LA     + P  NQVE++P   Q +L+ FCKSK I+V A+SPLG+  +      ++    + +IA  +      V + W +++G     KS N +R+K N +IF
Sbjct:   10 KILSLNTGAQIPQIGLGTWQSK--ENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKDS-----GVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGSTDA-----PLLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKIF 278          

BLAST of CV884403 vs. ExPASy Swiss-Prot
Match: ALDR_ENCCU (Aldose reductase OS=Encephalitozoon cuniculi GN=ECU01_0970 PE=1 SV=1)

HSP 1 Score: 172.555 bits (436), Expect = 2.623e-42
Identity = 100/272 (36.76%), Postives = 159/272 (58.46%), Query Frame = 1

Query:   46 KLSSASGHRKMPVIGLGSAVDNIDESAMKSAVLESIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVPALKKSLKTLQIEYVDLYLIHWPMSAKPSEK--LRNDIPEEDLVSLDYNGVWEAMEECQRHGLTKSIGVSNFSPKKIETILAFATIPPTVNQVEMNPAWQQRKLVEFCKSKSIIVTAFSPLGAVGSSWGTNQVMNNEALKQIAAVHGKTVAQVCLRWIIEQGATAAVKSFNKERLKENLEI 855
            K    +  +++P +GLG+     DE+ ++ A+  ++ LGYRH DTA +YG E+ +G  + +    G+V  R++LFIT+KLW  +         L++SL  LQ++YVDLYLIHWP++  P+    + +   + ++   D  GVW+ ME     GL KSIG+SNF     E IL    I P   Q+E++P   Q++LVEF KSK I V ++S LG+   S  + +V +++ +K IA  +G   +Q+ L +I  QG     KS +KE L+EN+++
Sbjct:    4 KTQKLNNGKEIPTVGLGTWGME-DEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDEGVV-QRKDLFITSKLW--NTFHGCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVISYSSLGSAPGS--SAKVRDDKTIKAIAKKYGCAPSQIILSYITAQGICVIPKSRSKEHLRENIDL 269