FC871159

BLAST of FC871159 vs. ExPASy Swiss-Prot
Match: CP21A_HUMAN (Steroid 21-hydroxylase OS=Homo sapiens GN=CYP21A2 PE=1 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 2.095e-11
Identity = 60/216 (27.78%), Postives = 97/216 (44.91%), Query Frame = 1

Query:   79 GNLHQLAGSLPHHGLRDLSKKYGPLMLLQLGQVPTVIVSSPEVANEVMKAHDVIFASRPHFPAAQIMSYNYRDIILSPYSDSWKQLRKICVSEILSAKRVQSFQSVREAEVSYLINWISSKAGSVVNLTENVYSLMYGITSRAAFGYRSRDQE---AFVSVIEEATKVIS--GFNIADIFPSIGLVQWLTGNKSQVEKLHQEADRIVENIINEHKK 711
            G LH L   LP + L  L++K+GP+  L LG    V+++S     E M      FA RP     +++S NY D+ L  YS  WK  +K+  S +L   R  S + V E         + ++ G+ V + E    L   I     FG + +D     A+   I+E  K  S     I D+ P +    +      ++++  ++ D IVE  + +HK+
Sbjct:   35 GFLHLLQPDLPIY-LLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYPDLSLGDYSLLWKAHKKLTRSALLLGIR-DSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTCSIICYLTFGDKIKDDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRF--FPNPGLRRLKQAIEKRDHIVEMQLRQHKE 246          

BLAST of FC871159 vs. ExPASy Swiss-Prot
Match: CP17A_RANDY (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Rana dybowskii GN=CYP17A1 PE=2 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 2.095e-11
Identity = 63/252 (25.00%), Postives = 113/252 (44.84%), Query Frame = 1

Query:    1 LKLEKKSETNNRISNLPPGPWK-------LPVIGNLHQLAGSLPHHGLR-DLSKKYGPLMLLQLGQVPTVIVSSPEVANEVMKAHDVIFASRPHFPAAQIMSYNYRDIILSPYSDSWKQLRKICVSEI-LSAKRVQSFQSVREAEVSYLINWISSKAGSVVNLTENVYSLMYGITSRAAFGYRSRDQEAFVSVIEEATK----VISGFNIADIFPSIGLVQWLTGNKSQVEKLHQEA---DRIVENIINEHK 708
            +KL + SE   R+ +   G  K       LPVIG+L  L   LP H L  +L KKYG L    +G    V+V++ E A EV+      F  RP      I++ + +DI  + YS +WK  RK+  S + +  +   + + +   E + L   ++S     +++   +   +  +     F  R +  +A    + + +K     ++  ++ DIFP + +          ++ L Q     D++++  INEHK
Sbjct:   19 IKLVRTSEKKWRMGSRSHGDVKHPKSLPSLPVIGSLLHLGKKLPPHILFCNLQKKYGSLYSFMMGSHYVVVVNNHEDAREVLLKKGKTFGGRPRTVTTDILTRDGKDIAFADYSPTWKFHRKMVHSALCMFGEGTVAIEQIISREAASLCQTLTSFQRIPLDMAPELIRAVTNVVCSLCFNTRYKRGDAEFETMLKYSKGIVDTVAKDSLVDIFPWLQIFP-----NKDLDILRQSVAARDQLLQKKINEHK 265          

BLAST of FC871159 vs. ExPASy Swiss-Prot
Match: CP2K3_ONCMY (Cytochrome P450 2K3 OS=Oncorhynchus mykiss GN=cyp2k3 PE=2 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 2.737e-11
Identity = 58/234 (24.79%), Postives = 100/234 (42.74%), Query Frame = 1

Query:   49 PPGPWKLPVIGNLHQLAGSLPHHGLRDLSKKYGPLMLLQLGQVPTVIVSSPEVANEVMKAHDVIFASRPHFPAAQIMSYNYRDIILSPYSDSWKQLRKICVSEI--LSAKRVQSFQSVREAEVSYLINWISSKAGSVVNLTENVYSLMYGITSRAAFGYR-SRDQEAFVSVIEEATKVI-----SGFNIADIFPSIG-LVQWLTGNKSQVEKLHQEADRIVENI---INEHKKR 714
            PPGP  LP++GN+ QL    P+  L +LSKKYG +     G    V+++  +   + +      F  R   P      +N    IL    DSWK++R+  ++ +      +  S + + E E+ YLI       G   + T++V   +  I S   +G R       F  + + A + I     +   + ++FP +G  +  LT  K  +  +  E   +V  +   +N H  R
Sbjct:   42 PPGPRPLPLLGNMLQLDLKKPYCTLCELSKKYGSIFTFHFGPKKVVVLAGYKTVKQALVNQAEDFGDRDITPV--FYDFNQGHGILFANGDSWKEMRRFALTNLRDFGMGKKGSEEKILE-EIPYLIEVFEKHEGKAFDTTQSVLYAVSNIISAIVYGSRFEYTDPLFTGMADRAKESIHLTGSASIQMYNMFPWLGPWINNLTRLKKNIADMKMEVTELVRGLKETLNPHMCR 272          

BLAST of FC871159 vs. ExPASy Swiss-Prot
Match: CP21A_CANLU (Steroid 21-hydroxylase OS=Canis lupus GN=CYP21 PE=3 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 2.737e-11
Identity = 63/235 (26.81%), Postives = 108/235 (45.96%), Query Frame = 1

Query:   55 GPWKL------PVI-GNLHQLAGSLPHHGLRDLSKKYGPLMLLQLGQVPTVIVSSPEVANEVMKAHDVIFASRPHFPAAQIMSYNYRDIILSPYSDSWKQLRKICVSEILSAKRVQSFQSVREAEVSYLINWISSKAGSVVNLTENVYSLMYGITSRAAFGYRSRD-QEAFVSVIEEATKVISGFNIADI--------FPSIGLVQWLTGNKSQVEKLHQEADRIVENIINEHKK 711
            G WKL      P++ G LH L   LP H L  L++K GP+  L+LG    V+++S     E M    V FA RP  P+ +++S +++D+ L  YS  WK  +K+  S +L   R  S + + E         + ++AG+ V + +    L   I     FG +       F   +++  +    ++I  +        FP+ GL  W      ++++  +  D IVE  + +HK+
Sbjct:   20 GKWKLRGLHLPPLVPGCLHLLQPDLPLH-LLGLTQKLGPIYRLRLGLQDVVVLNSKRTIEEAMVRKWVDFAGRPQTPSYKLVSLHHQDLSLGDYSLLWKAHKKLTRSALLLGIR-SSMEPLVEQLTQEFCERMRAQAGTPVAIQKEFSLLTCAIICHLTFGDKEDTLVHTFHDCVQDLMRTWEHWSIQMLDIIPFLRFFPNPGL--W------RLKRALENRDHIVEKQLRQHKE 244          

BLAST of FC871159 vs. ExPASy Swiss-Prot
Match: CP21A_CANFA (Steroid 21-hydroxylase OS=Canis familiaris GN=CYP21 PE=3 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 2.737e-11
Identity = 63/235 (26.81%), Postives = 108/235 (45.96%), Query Frame = 1

Query:   55 GPWKL------PVI-GNLHQLAGSLPHHGLRDLSKKYGPLMLLQLGQVPTVIVSSPEVANEVMKAHDVIFASRPHFPAAQIMSYNYRDIILSPYSDSWKQLRKICVSEILSAKRVQSFQSVREAEVSYLINWISSKAGSVVNLTENVYSLMYGITSRAAFGYRSRD-QEAFVSVIEEATKVISGFNIADI--------FPSIGLVQWLTGNKSQVEKLHQEADRIVENIINEHKK 711
            G WKL      P++ G LH L   LP H L  L++K GP+  L+LG    V+++S     E M    V FA RP  P+ +++S +++D+ L  YS  WK  +K+  S +L   R  S + + E         + ++AG+ V + +    L   I     FG +       F   +++  +    ++I  +        FP+ GL  W      ++++  +  D IVE  + +HK+
Sbjct:   20 GKWKLRGLHLPPLVPGCLHLLQPDLPLH-LLGLTQKLGPIYRLRLGLQDVVVLNSKRTIEEAMVRKWVDFAGRPQTPSYKLVSLHHQDLSLGDYSLLWKAHKKLTRSALLLGIR-SSMEPLVEQLTQEFCERMRAQAGTPVAIQKEFSLLTCAIICHLTFGDKEDTLVHTFHDCVQDLMRTWEHWSIQMLDIIPFLRFFPNPGL--W------RLKRALENRDHIVEKQLRQHKE 244          

BLAST of FC871159 vs. ExPASy Swiss-Prot
Match: CP2M1_ONCMY (Cytochrome P450 2M1 OS=Oncorhynchus mykiss GN=cyp2m1 PE=1 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 3.574e-11
Identity = 47/185 (25.41%), Postives = 86/185 (46.49%), Query Frame = 1

Query:   40 SNLPPGPWKLPVIGNLHQLAGSLPHHGLRDLSKKYGPLMLLQLGQVPTVIVSSPEVANEVMKAHDVIFASRPHFPAAQIMSYNYRDIILSPYSDSWKQLRKICVSEILS-AKRVQSFQSVREAEVSYLINWISSKAGSVVNLTENVYSLMYGITSRAAFGYRSRDQEAFVSVIEEATKVISGFNI 591
            S LPPGP  +P++GNL ++    P+    +LSKKYG +  + LG  P V++S  +   +        F+ R ++P    +S  Y  ++ S      K LR+  +  + +     +S +   + E   L+        SVVN  E + + +  +     FG+R  + +    +I++A  V + FN+
Sbjct:   34 SRLPPGPAPIPLLGNLLRMDVKAPYKLYMELSKKYGSVFTVWLGSKPVVVISGYQAIKDAFVTQGEEFSGRANYPVIMTVSKGYGVLVSS--GKRSKDLRRFSLMTLKTFGMGRRSIEERVQEEAKMLVKAFGEYRDSVVNPKELLCNCVGNVICSIVFGHRFENDDPMFQLIQKA--VDAYFNV 214          

BLAST of FC871159 vs. ExPASy Swiss-Prot
Match: CP2J1_RABIT (Cytochrome P450 2J1 OS=Oryctolagus cuniculus GN=CYP2J1 PE=1 SV=2)

HSP 1 Score: 68.9366 bits (167), Expect = 3.574e-11
Identity = 58/233 (24.89%), Postives = 102/233 (43.78%), Query Frame = 1

Query:   34 RISNLPPGPWKLPVIGNLHQLAGSLPHHGLRDLSKKYGPLMLLQLGQVPTVIVSSPEVANEVMKAHDVIFASRPHFPAAQIMSYNYRDIILSPYSDSWKQLRKICVSEILS-AKRVQSFQSVREAEVSYLINWISSKAGSVVN----LTENVYSLMYGITSRAAFGYRSRDQEAFVSVIEEATKVISGF--NIADIFPSIGLVQWLTGNKSQVEKLHQEADRIVENIINEHKK 711
            R  N PPGPW+LP +GNL  L     H  L+   KKYG L  L L     VIV+   +  EV+   D  F +RP  P  +  S+    +I+S     WK+ R+  +  + +     +S +   + E  +L   +  + G   +    +   V +++  IT    F Y     +  + + +E   + +     + +IFP I  +++L G    +    ++ +  V  ++  HKK
Sbjct:   39 RPKNYPPGPWRLPFLGNLFTLDMEKSHLQLQQFVKKYGNLFCLDLAGKSIVIVTGLPLIKEVLVHMDQNFINRP-VPPIRERSFKKNGLIMSS-GQLWKEQRRFALMTLRNFGLGKKSLEERIQEEARHLTEAMEKEGGQPFDAHFKINNAVSNIICSITFGERFEYHDGQFQELLKLFDEVMYLEASMLCQLYNIFPWI--MKFLPGAHQTLFSNWKKLELFVSRMLENHKK 267          

BLAST of FC871159 vs. ExPASy Swiss-Prot
Match: CP2D9_MOUSE (Cytochrome P450 2D9 OS=Mus musculus GN=Cyp2d9 PE=1 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 3.574e-11
Identity = 54/233 (23.18%), Postives = 110/233 (47.21%), Query Frame = 1

Query:   40 SNLPPGPWKLPVIGNLHQL-AGSLPHHGLRDLSKKYGPLMLLQLGQVPTVIVSSPEVANEVMKAHDVIFASRPHFPAAQIMSY--NYRDIILSPYSDSWKQLRKICVSEILS-AKRVQSFQSVREAEVSYLINWISSKAGSVVN----LTENVYSLMYGITSRAAFGYRSRDQEAFVSVIEEATKVISGF--NIADIFPSIGLVQWLTGNKSQVEKLHQEADRIVENIINEHK 708
            S  PPGP   PV+GNL Q+  G++P + L  L  +YG +  LQ+   P V+++  +   E++       A RP  P  + +      + ++L+PY   W++ R+  VS + +     +S +     E ++L +  +++AG  +N    L ++  +++  +     F Y        + V+E++   +SG    + + FP +  +  L     Q +K       I++N++ E++
Sbjct:   34 SRYPPGPVPWPVLGNLLQVDLGNMP-YSLYKLQNRYGDVFSLQMAWKPMVVINGLKAMKEMLLTCGEDTADRPPVPIFEYLGVKPGSQGVVLAPYGPEWREQRRFSVSTLRNFGLGKKSLEDWVTKEANHLCDAFTAQAGQPINPNPMLNKSTCNVIASLIFARRFEYEDPFLIRMLKVLEQSLTEVSGLIPEVLNAFPILLRIPRLADKALQGQK---SFIAILDNLLTENR 262          

BLAST of FC871159 vs. ExPASy Swiss-Prot
Match: CP2DQ_RAT (Cytochrome P450 2D26 OS=Rattus norvegicus GN=Cyp2d26 PE=2 SV=2)

HSP 1 Score: 68.5514 bits (166), Expect = 4.668e-11
Identity = 52/231 (22.51%), Postives = 105/231 (45.45%), Query Frame = 1

Query:   40 SNLPPGPWKLPVIGNLHQLAGSLPHHGLRDLSKKYGPLMLLQLGQVPTVIVSSPEVANEVMKAHDVIFASRPHFPAAQIMSYNYRD--IILSPYSDSWKQLRKICVSEILS-AKRVQSFQSVREAEVSYLINWISSKAGSVVN----LTENVYSLMYGITSRAAFGYRSRDQEAFVSVIEEATKVISGFNIADIFPSIGLVQWLTGNKSQVEKLHQEADRIVENIINEHKK 711
            ++ PPGP  LP +GNL Q+      + L  L  +YG +  LQ+   P V+++  +   E++  +    A RP  P    + Y  +   ++L+PY   W++ R+  VS +       +S +     E  +L +  + +A    N    L++ V +++  +     F Y        +  ++E+    +GF +A++  +I ++  + G   +V         +V+ ++ EHKK
Sbjct:   34 AHYPPGPVPLPGLGNLLQVDFENMPYSLYKLRSRYGDVFSLQIAWKPVVVINGLKAVRELLVTYGEDTADRPLLPIYNHLGYGNKSKGVVLAPYGPEWREQRRFSVSTLRDFGVGKKSLEQWVTEEAGHLCDTFAKEAEHPFNPSILLSKAVSNVIASLVYARRFEYEDPFFNRMLKTLKESFGEDTGF-MAEVLNAIPILLQIPGLPGKVFPKLNSFIALVDKMLIEHKK 263          

BLAST of FC871159 vs. ExPASy Swiss-Prot
Match: CP254_MOUSE (Cytochrome P450 2C54 OS=Mus musculus GN=Cyp2c54 PE=2 SV=1)

HSP 1 Score: 68.5514 bits (166), Expect = 4.668e-11
Identity = 60/229 (26.20%), Postives = 103/229 (44.98%), Query Frame = 1

Query:   46 LPPGPWKLPVIGNLHQLAGSLPHHGLRDLSKKYGPLMLLQLGQVPTVIVSSPEVANEVMKAHDVIFASRPHFPAAQIMSYNYRDIILSPYSDSWKQLRKICVSEILS-AKRVQSFQSVREAEVSYLINWISSKAGSVVNLTENV----YSLMYGITSRAAFGYRSRDQEAFVSVIEEATKVIS--GFNIADIFPSIGLVQWLTGNKSQVEKLHQEADRIVENIINEHKK 711
            LPPGP  LP+IGN+ Q+          +LS+ YGP+  L LG+ PTV++   E   E +  H  +FA R   P     + N   I  S  S  WK  R   +  + +     +S +   + E   L+  +    GS  + T  +     +++  I  +  F Y+ RD    +  ++E +K++S     + + FP+  L+ +  G+ +Q  K +      +   I EHK+
Sbjct:   29 LPPGPTPLPIIGNILQIDVKDICQSFTNLSRVYGPVYTLYLGRKPTVVLHGYEAVKEALVDHGDVFAGRGRLPVFD-KATNGMGIGFSNGS-VWKNTRHFSLMTLRNLGMGKRSIEDRVQEEARCLVEELRKTNGSPCDPTFILGCAPCNVICSIIFQDRFDYKDRDFLNLLEKLDEISKILSTPWLQVCNTFPA--LLDYCPGSHNQFFKNYAYIKNFLLEKIREHKE 253