CX290879

BLAST of CX290879 vs. ExPASy Swiss-Prot
Match: XYL1_ASPNG (NAD(P)H-dependent D-xylose reductase OS=Aspergillus niger GN=xyrA PE=3 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 3.843e-14
Identity = 38/94 (40.43%), Postives = 55/94 (58.51%), Query Frame = 1

Query:   82 STGKSIPLVGFGTVEYPLNEAFKERVLHAIKLGYRHFDTAAAYPSEQPLGEALTEALRLGLVQSGDELFITSKLWLTDSYRGRVIPGLQKNSQD 363
            ++G  +PLVGFG  +   N+   +++ HAIK GYR FD A  Y +E   G+ +  A++ GLV+  +ELFI SKLW +     RV P  +K   D
Sbjct:    9 NSGYDMPLVGFGLWKVN-NDTCADQIYHAIKEGYRLFDGACDYGNEVEAGQGIARAIKDGLVKR-EELFIVSKLWNSFHDGDRVEPICRKQLAD 100          

HSP 2 Score: 34.6538 bits (78), Expect = 3.843e-14
Identity = 13/23 (56.52%), Postives = 18/23 (78.26%), Query Frame = 2

Query:  347 KKTLKTLGLEYLDLYLVHFPVSL 415
            +K L   G++Y DLY+VHFP+SL
Sbjct:   95 RKQLADWGIDYFDLYIVHFPISL 117          

BLAST of CX290879 vs. ExPASy Swiss-Prot
Match: ALDR_RAT (Aldose reductase OS=Rattus norvegicus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 58.151 bits (139), Expect = 3.844e-14
Identity = 37/94 (39.36%), Postives = 50/94 (53.19%), Query Frame = 1

Query:   82 STGKSIPLVGFGTVEYPLNEAFKERVLHAIKLGYRHFDTAAAYPSEQPLGEALTEALRLGLVQSGDELFITSKLWLTDSYRGRVIPGLQKNSQD 363
            + G  +P +G GT + P  +   E V  AI +GYRH D A  Y +E+ +G AL E L+  +V+  D LFI SKLW T   +  V    QK   D
Sbjct:    8 NNGTKMPTLGLGTWKSPPGQV-TEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQD-LFIVSKLWCTFHDQSMVKGACQKTLSD 99          

HSP 2 Score: 38.891 bits (89), Expect = 3.844e-14
Identity = 25/67 (37.31%), Postives = 34/67 (50.75%), Query Frame = 2

Query:  341 AYKKTLKTLGLEYLDLYLVHFPVS-------LILEATCPVKPEDIRSFDYEGVWEEMEKCQELGPTK 520
            A +KTL  L L+YLDLYL+H+P           L+A+  V P D    D+   W  ME+  + G  K
Sbjct:   92 ACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDT---DFVDTWTAMEQLVDEGLVK 155          

BLAST of CX290879 vs. ExPASy Swiss-Prot
Match: AK1CD_MESAU (Aldo-keto reductase family 1 member C13 OS=Mesocricetus auratus GN=AKR1C13 PE=1 SV=1)

HSP 1 Score: 65.855 bits (159), Expect = 4.992e-14
Identity = 38/91 (41.76%), Postives = 57/91 (62.64%), Query Frame = 1

Query:   88 GKSIPLVGFGT---VEYPLNEAFKERVLHAIKLGYRHFDTAAAYPSEQPLGEALTEALRLGLVQSGDELFITSKLWLTDSYRGRVIPGLQK 351
            G  IP +GFGT   +E P ++A +   L AI +GYRH DTA AY  E+ +G+A+   ++ G+V+  +++FIT+KLW T      V P L+K
Sbjct:   13 GHCIPALGFGTYKPIEVPKSKAMEAANL-AIGVGYRHIDTAYAYQIEEEIGQAIQSNIKAGIVKR-EDMFITTKLWCTCFQPELVRPSLEK 101          

HSP 2 Score: 30.8018 bits (68), Expect = 4.992e-14
Identity = 17/62 (27.42%), Postives = 33/62 (53.23%), Query Frame = 2

Query:  347 KKTLKTLGLEYLDLYLVHFPVSLIL-EATCPVKPED---IRSFDYEGVWEEMEKCQELGPTK 520
            +K    L LE++DL+++H+PV +   +   P+  +    + + D+   WE +EK  + G  K
Sbjct:  100 EKXXXKLQLEHVDLFIMHYPVPMKAGDNDFPLDEQGKLLLDTVDFCATWEALEKXXDAGLVK 161          

BLAST of CX290879 vs. ExPASy Swiss-Prot
Match: ALD1_MOUSE (Aldose reductase-related protein 1 OS=Mus musculus GN=Akr1b7 PE=2 SV=4)

HSP 1 Score: 58.5362 bits (140), Expect = 4.994e-14
Identity = 37/94 (39.36%), Postives = 49/94 (52.13%), Query Frame = 1

Query:   82 STGKSIPLVGFGTVEYPLNEAFKERVLHAIKLGYRHFDTAAAYPSEQPLGEALTEALRLGLVQSGDELFITSKLWLTDSYRGRVIPGLQKNSQD 363
            ST   +PLVG GT +    +  KE V  AI  GYRH D A  Y +E  +GEA+ E ++   V+  ++LFI SKLW T   +  V    Q    D
Sbjct:    8 STKAKMPLVGLGTWKSSPGQV-KEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIKENAVKR-EDLFIVSKLWATFFEKSLVKKAFQNTLSD 99          

HSP 2 Score: 38.1206 bits (87), Expect = 4.994e-14
Identity = 23/67 (34.33%), Postives = 35/67 (52.24%), Query Frame = 2

Query:  338 RAYKKTLKTLGLEYLDLYLVHFPVSLILEATCPVKPED------IRSFDYEGVWEEMEKCQELGPTK 520
            +A++ TL  L L+YLDLYLVH+P     +A   + P+D      +    +   WE ME+  + G  K
Sbjct:   91 KAFQNTLSDLKLDYLDLYLVHWPQG--FQAGNALLPKDNKGKVLLSKSTFLDAWEAMEELVDQGLVK 155          

BLAST of CX290879 vs. ExPASy Swiss-Prot
Match: ALRC_DICDI (Aldose reductase C OS=Dictyostelium discoideum GN=alrC PE=3 SV=1)

HSP 1 Score: 54.6842 bits (130), Expect = 6.487e-14
Identity = 32/96 (33.33%), Postives = 50/96 (52.08%), Query Frame = 1

Query:   88 GKSIPLVGFGTVEYPLNEAFKERVLHAIKLGYRHFDTAAAYPSEQPLGEALTEALRLGLVQSGDELFITSKLWLTDSYRGRVIPGLQKNSQDSWIG 375
            G  IP +G GT          + + +A+K GYRH D AA Y +E+ +G +L E  + G ++  +++F TSKLW +      V+    K  +D  IG
Sbjct:   22 GNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEGEIKR-EDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIG 116          

HSP 2 Score: 41.5874 bits (96), Expect = 6.487e-14
Identity = 25/69 (36.23%), Postives = 38/69 (55.07%), Query Frame = 2

Query:  350 KTLKTLGLEYLDLYLVHFPVS--------LILEATCPVKPED----IRSFDYEGVWEEMEKCQELGPTK 520
            KT++ LG+ YLDLYL+H+P++        L +E   P++ ++    I        W+EMEK  ELG  K
Sbjct:  108 KTIEDLGIGYLDLYLIHWPIAFENSNPLGLTIE---PLRDQNGNPIIAPVSIRETWQEMEKLVELGLVK 173          

BLAST of CX290879 vs. ExPASy Swiss-Prot
Match: AK1D1_RAT (3-oxo-5-beta-steroid 4-dehydrogenase OS=Rattus norvegicus GN=Akr1d1 PE=1 SV=1)

HSP 1 Score: 58.151 bits (139), Expect = 8.423e-14
Identity = 41/106 (38.68%), Postives = 53/106 (50.00%), Query Frame = 1

Query:   49 MRTAIPEEPLGSTGKSIPLVGFGTVEYPLNEAFKE--RVLHAIKLGYRHFDTAAAYPSEQPLGEALTEALRLGLVQSGDELFITSKLWLTDSYRGRVIPGLQKNSQ 360
            + TA    PL   G SIP++G GT   P     K    V  AI  GYRH D A  Y +E  +GEA+ E +  G V+  +E+F   KLW TD     V P L++  Q
Sbjct:    3 LSTANHHIPLND-GNSIPIIGLGTYSDPRPVPGKTFIAVKTAIDEGYRHIDGAYVYRNEHEVGEAIREKVAEGKVKR-EEIFYCGKLWSTDHDPEMVRPALERTLQ 106          

HSP 2 Score: 37.7354 bits (86), Expect = 8.423e-14
Identity = 20/64 (31.25%), Postives = 35/64 (54.69%), Query Frame = 2

Query:  341 AYKKTLKTLGLEYLDLYLVHFPVSLILEATCPVKPEDIRSFDYE----GVWEEMEKCQELGPTK 520
            A ++TL+TL L+Y+DLY++  P++         K E+ R   ++      WE +E C++ G  K
Sbjct:  100 ALERTLQTLKLDYIDLYIIEMPMAFKPGEEFYPKDENGRVIYHKSNLCATWEALEACKDAGLVK 163          

BLAST of CX290879 vs. ExPASy Swiss-Prot
Match: DHB5_MOUSE (Estradiol 17 beta-dehydrogenase 5 OS=Mus musculus GN=Akr1c6 PE=1 SV=1)

HSP 1 Score: 51.9878 bits (123), Expect = 8.425e-14
Identity = 31/80 (38.75%), Postives = 48/80 (60.00%), Query Frame = 1

Query:   82 STGKSIPLVGFGTV---EYPLNEAFKERVLHAIKLGYRHFDTAAAYPSEQPLGEALTEALRLGLVQSGDELFITSKLWLT 312
            S G  IP++GFGT    E P ++A  E    AI  G+RH D+A+ Y +E+ +G A+   +  G V+  +++F TSK+W T
Sbjct:   11 SDGHFIPILGFGTYAPQEVPKSKA-TEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKIADGTVKR-EDIFYTSKVWCT 88          

HSP 2 Score: 43.8986 bits (102), Expect = 8.425e-14
Identity = 23/62 (37.10%), Postives = 37/62 (59.68%), Query Frame = 2

Query:  347 KKTLKTLGLEYLDLYLVHFPVSLILEATCPVKPEDIR----SFDYEGVWEEMEKCQELGPTK 520
            +++LK L L+Y+DLYL+HFP+++        K E+ +    + D    WE MEKC++ G  K
Sbjct:  100 EQSLKQLQLDYVDLYLIHFPMAMKPGENYLPKDENGKLIYDAVDICDTWEAMEKCKDAGLAK 161          

BLAST of CX290879 vs. ExPASy Swiss-Prot
Match: YBN4_SCHPO (Uncharacterized oxidoreductase C8E4.04 OS=Schizosaccharomyces pombe GN=SPBC8E4.04 PE=2 SV=1)

HSP 1 Score: 56.6102 bits (135), Expect = 1.421e-13
Identity = 35/92 (38.04%), Postives = 51/92 (55.43%), Query Frame = 1

Query:   88 GKSIPLVGFGTVEYPLNEAFKERVLHAIKLGYRHFDTAAAYPSEQPLGEALTEALRLGLVQSGDELFITSKLWLTDSYRGRVIPGLQKNSQD 363
            G  IP +G GT     +E  K  V  A+K GYRH DTA  Y +E+ +GE + E+   G+ ++  ++++TSKLW      G V   L+K  QD
Sbjct:   20 GDKIPSIGLGTWRSGKDET-KNAVCAALKAGYRHIDTAHIYGNEKEIGEGIRES---GVPRT--DIWVTSKLWCNAHRAGLVPLALEKTLQD 105          

HSP 2 Score: 38.5058 bits (88), Expect = 1.421e-13
Identity = 24/64 (37.50%), Postives = 34/64 (53.12%), Query Frame = 2

Query:  341 AYKKTLKTLGLEYLDLYLVHFPVSLIL---EATCPVKPEDI-RSFDYEGVWEEMEKCQELGPTK 520
            A +KTL+ L LEY+D YL+H+P +L+    E     K E I      E  W+ ME+  E G  +
Sbjct:   98 ALEKTLQDLNLEYIDAYLIHWPFALLSGPEELPRNEKGELIYEDVPIEETWQAMEELLETGKVR 161          

BLAST of CX290879 vs. ExPASy Swiss-Prot
Match: GRE3_YEAST (NADPH-dependent aldose reductase GRE3 OS=Saccharomyces cerevisiae GN=GRE3 PE=1 SV=1)

HSP 1 Score: 55.4546 bits (132), Expect = 1.846e-13
Identity = 34/94 (36.17%), Postives = 51/94 (54.26%), Query Frame = 1

Query:   82 STGKSIPLVGFGTVEYPLNEAFKERVLHAIKLGYRHFDTAAAYPSEQPLGEALTEALRLGLVQSGDELFITSKLWLTDSYRGRVIPGLQKNSQD 363
            + G  +PLVG G  +    +    ++  AIKLGYR FD A  Y +E+ +GE + +A+  GLV S  ++F+ SKLW    +   V   L+K   D
Sbjct:    8 NNGLKMPLVGLGCWKID-KKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEGLV-SRKDIFVVSKLWNNFHHPDHVKLALKKTLSD 99          

HSP 2 Score: 39.2762 bits (90), Expect = 1.846e-13
Identity = 15/24 (62.50%), Postives = 20/24 (83.33%), Query Frame = 2

Query:  341 AYKKTLKTLGLEYLDLYLVHFPVS 412
            A KKTL  +GL+YLDLY +HFP++
Sbjct:   92 ALKKTLSDMGLDYLDLYYIHFPIA 115          

BLAST of CX290879 vs. ExPASy Swiss-Prot
Match: AK1D1_MOUSE (3-oxo-5-beta-steroid 4-dehydrogenase OS=Mus musculus GN=Akr1d1 PE=2 SV=1)

HSP 1 Score: 59.3066 bits (142), Expect = 2.398e-13
Identity = 36/92 (39.13%), Postives = 49/92 (53.26%), Query Frame = 1

Query:   82 STGKSIPLVGFGTVEYPLNEAFKERVL--HAIKLGYRHFDTAAAYPSEQPLGEALTEALRLGLVQSGDELFITSKLWLTDSYRGRVIPGLQK 351
            S G +IPL+G GT   P     K  V    AI  GYRH D A  Y +E  +GEA+ E +  G V+  +E+F   KLW T+     V+P L++
Sbjct:   13 SDGNNIPLIGLGTYSDPRPVPGKTYVAVKTAIDEGYRHIDGAYVYHNEHEVGEAIREKIAEGKVKR-EEIFYCGKLWNTEHVPSMVLPALER 103          

HSP 2 Score: 35.039 bits (79), Expect = 2.398e-13
Identity = 19/64 (29.69%), Postives = 33/64 (51.56%), Query Frame = 2

Query:  341 AYKKTLKTLGLEYLDLYLVHFPVSLILEATCPVKPEDIR----SFDYEGVWEEMEKCQELGPTK 520
            A ++TLK L L+Y+DLY++  P++         + E+ R      +    WE +E C++ G  K
Sbjct:  100 ALERTLKALKLDYIDLYIIELPMAFKPGKEIYPRDENGRIIYDKTNLCATWEALEACKDAGLVK 163