CX295006

BLAST of CX295006 vs. ExPASy Swiss-Prot
Match: M3K2_MOUSE (Mitogen-activated protein kinase kinase kinase 2 OS=Mus musculus GN=Map3k2 PE=1 SV=2)

HSP 1 Score: 129.028 bits (323), Expect = 1.840e-29
Identity = 79/197 (40.10%), Postives = 111/197 (56.35%), Query Frame = 3

Query:   33 TISNTCPFSPSYSTATSPSVPRSPGRVENPT------SPGSR-------WKKGRLLGRGTFGHVYLGFNSESGEMCAMKEVTLFSDDAKSKESAQQLGQEIALLSRLRHPNIVRYYGS--ETLDDKLYIYLEYVSGGSIYKILQDYGQLGESAIRSYTQQILSGLEYLHAKNTVHRDIKGANILVDPSG-V*IGDFG 575
            T S +  F+P Y  +    + R    ++NPT      SP SR       W+ G+LLG+G FG VYL ++ ++G   A+K+V    +  ++ +    L  EI LL  L H  IV+YYG   +  +  L I++E   GGSI   L+ YG L E+  R YT+QIL G+ YLH+   VHRDIKGANIL D +G + +GDFG
Sbjct:  310 TSSGSSVFTPEYDDSR---IRRRGSDIDNPTLTVTDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFG 503          

BLAST of CX295006 vs. ExPASy Swiss-Prot
Match: STE11_YEAST (Serine/threonine-protein kinase STE11 OS=Saccharomyces cerevisiae GN=STE11 PE=1 SV=3)

HSP 1 Score: 126.331 bits (316), Expect = 1.192e-28
Identity = 77/199 (38.69%), Postives = 104/199 (52.26%), Query Frame = 3

Query:  102 PGRVENPTSPGSRWKKGRLLGRGTFGHVYLGFNSESGEMCAMKEVTL---------------FSDDAKSKESAQQ------------------------LGQEIALLSRLRHPNIVRYYGSETLDDKLYIYLEYVSGGSIYKILQDYGQLGESAIRSYTQQILSGLEYLHAKNTVHRDIKGANILVDPSG-V*IGDFGM 578
            P ++  P +    W KG  +G G+FG VYLG N+ +GE+ A+K+V +                SD+   +E  Q+                        L  E+ LL  L H NIV YYG+      L I+LEYV GGS+  +L +YG   ES I ++T+QIL G+ YLH KN +HRDIKGANIL+D  G V I DFG+
Sbjct:  406 PTKIATPKN----WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGI 600          

BLAST of CX295006 vs. ExPASy Swiss-Prot
Match: STE11_YEAS7 (Serine/threonine-protein kinase STE11 OS=Saccharomyces cerevisiae (strain YJM789) GN=STE11 PE=3 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 1.192e-28
Identity = 77/199 (38.69%), Postives = 104/199 (52.26%), Query Frame = 3

Query:  102 PGRVENPTSPGSRWKKGRLLGRGTFGHVYLGFNSESGEMCAMKEVTL---------------FSDDAKSKESAQQ------------------------LGQEIALLSRLRHPNIVRYYGSETLDDKLYIYLEYVSGGSIYKILQDYGQLGESAIRSYTQQILSGLEYLHAKNTVHRDIKGANILVDPSG-V*IGDFGM 578
            P ++  P +    W KG  +G G+FG VYLG N+ +GE+ A+K+V +                SD+   +E  Q+                        L  E+ LL  L H NIV YYG+      L I+LEYV GGS+  +L +YG   ES I ++T+QIL G+ YLH KN +HRDIKGANIL+D  G V I DFG+
Sbjct:  406 PTKIATPKN----WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGI 600          

BLAST of CX295006 vs. ExPASy Swiss-Prot
Match: MKH1_SCHPO (MAP kinase kinase kinase mkh1 OS=Schizosaccharomyces pombe GN=mkh1 PE=2 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 1.192e-28
Identity = 64/156 (41.03%), Postives = 97/156 (62.18%), Query Frame = 3

Query:  138 RWKKGRLLGRGTFGHVYLGFNSESGEMCAMKEVTLFSD-----DAKSKESAQQLGQEIALLSRLRHPNIVRYYGSETLDDKLYIYLEYVSGGSIYKILQDYGQLGESAIRSYTQQILSGLEYLHAKNTVHRDIKGANILVDPSGV-*IGDFGMEAY 587
            +W KG L+G GT+G V+L  N  +GE+ A+K+V +        D   K+    +  EI++++ L H NIV+Y G E  +  + I+LEYVSGGSI + L++YG   E  +R  ++Q+L GL YLH+K  +HRD+K  N+L+D  GV  I DFG+  +
Sbjct:  824 KWMKGELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEISMIADLDHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLRNYGPFEEQLVRFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGISKH 979          

BLAST of CX295006 vs. ExPASy Swiss-Prot
Match: WIS4_SCHPO (MAP kinase kinase kinase wis4 OS=Schizosaccharomyces pombe GN=wis4 PE=2 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 5.918e-28
Identity = 61/151 (40.40%), Postives = 93/151 (61.59%), Query Frame = 3

Query:  138 RWKKGRLLGRGTFGHVYLGFNSESGEMCAMKEVTLFSDDAKSKESAQQLGQEIALLSRLRHPNIVRYYGSETLDDKLYIYLEYVSGGSIYKILQDYGQLGESAIRSYTQQILSGLEYLHAKNTVHRDIKGANILVDPSG-V*IGDFGMEAY 587
            RW++G  +  G FG VY G N E+G++ A+KE+ L  D    + +  Q+  E+ +L RL HPN+V YYG E   +K+YI++E+  GGS+  +L       E+ ++ Y  Q+L GL Y+H+++ +HRDIK ANIL+D  G +   DFG   Y
Sbjct: 1036 RWQQGHFVRSGMFGDVYTGVNMETGDLLAVKEIKL-QDSRTFRSTVDQIHNEMTVLERLNHPNVVTYYGVEVHREKVYIFMEFCQGGSLADLLAHGRIEDENVLKVYVVQLLEGLAYIHSQHILHRDIKPANILLDHRGMIKYSDFGSALY 1185          

BLAST of CX295006 vs. ExPASy Swiss-Prot
Match: STE11_YEAS6 (Serine/threonine-protein kinase STE11 OS=Saccharomyces cerevisiae (strain AWRI1631) GN=STE11 PE=3 SV=2)

HSP 1 Score: 124.02 bits (310), Expect = 5.918e-28
Identity = 76/199 (38.19%), Postives = 103/199 (51.76%), Query Frame = 3

Query:  102 PGRVENPTSPGSRWKKGRLLGRGTFGHVYLGFNSESGEMCAMKEVTL---------------FSDDAKSKESAQQ------------------------LGQEIALLSRLRHPNIVRYYGSETLDDKLYIYLEYVSGGSIYKILQDYGQLGESAIRSYTQQILSGLEYLHAKNTVHRDIKGANILVDPSG-V*IGDFGM 578
            P ++  P +    W KG  +G G+FG VYLG N+ +GE+ A+K+V +                SD+   +E  Q+                        L  E+ LL  L H NIV YYG+      L I+LEYV GGS+  +L +YG   ES I ++T+QIL G+ YLH K  +HRDIKGANIL+D  G V I DFG+
Sbjct:  406 PTKIATPKN----WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVSTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKKIIHRDIKGANILIDIKGCVKITDFGI 600          

BLAST of CX295006 vs. ExPASy Swiss-Prot
Match: SSK22_YEAST (Serine/threonine-protein kinase SSK22 OS=Saccharomyces cerevisiae GN=SSK22 PE=1 SV=2)

HSP 1 Score: 120.168 bits (300), Expect = 8.545e-27
Identity = 68/171 (39.77%), Postives = 98/171 (57.31%), Query Frame = 3

Query:   93 PRSPGRVENPTSPGS---------------RWKKGRLLGRGTFGHVYLGFNSESGEMCAMKEVTLFSDDAKSKESAQQLGQEIALLSRLRHPNIVRYYGSETLDDKLYIYLEYVSGGSIYKILQDYGQL-GESAIRSYTQQILSGLEYLHAKNTVHRDIKGANILVDPSGV 557
            PR  G+V + T  G+               RW+K   +G GTFG VY   N E+GE+ A+KE+ +  D    K+    + +E+ +L  L HPNIV+YYG E   DK+ I++EY  GGS+  +L D+G++  E   + YT ++L GL YLH    VHRDIK  NIL+D +G+
Sbjct: 1003 PRQMGKVLDATDQGNKYLLSLASSLSNVSMRWQKRSFIGGGTFGQVYSAINLENGEILAVKEIKIH-DTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLL-DHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGI 1171          

BLAST of CX295006 vs. ExPASy Swiss-Prot
Match: M3K1_HUMAN (Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens GN=MAP3K1 PE=1 SV=4)

HSP 1 Score: 119.013 bits (297), Expect = 1.904e-26
Identity = 58/162 (35.80%), Postives = 95/162 (58.64%), Query Frame = 3

Query:  108 RVENPTSPGSRWKKGRLLGRGTFGHVYLGFNSESGEMCAMKEVTLFSDDAKSKESA-QQLGQEIALLSRLRHPNIVRYYGSETLDDKLYIYLEYVSGGSIYKILQDYGQLGESAIRSYTQQILSGLEYLHAKNTVHRDIKGANILVDPSG--V*IGDFGMEA 584
            + + P    + W KG+ +G G F   Y   +  +G + A+K+VT   + +  +E   + L +EI ++S L HPNI+R  G+        +++E+++GGS+  +L  YG   ES + +YT+Q+L GL YLH    +HRD+KGAN+L+D +G  + I DFG  A
Sbjct: 1232 KAKQPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAA 1393          

BLAST of CX295006 vs. ExPASy Swiss-Prot
Match: BCK1_YEAST (Serine/threonine-protein kinase BCK1/SLK1/SSP31 OS=Saccharomyces cerevisiae GN=BCK1 PE=1 SV=1)

HSP 1 Score: 118.627 bits (296), Expect = 2.486e-26
Identity = 60/150 (40.00%), Postives = 96/150 (64.00%), Query Frame = 3

Query:  141 WKKGRLLGRGTFGHVYLGFNSESGEMCAMKEVTLFSDDAKSK---ESAQQLGQEIALLSRLRHPNIVRYYGSETLDDKLYIYLEYVSGGSIYKILQDYGQLGESAIRSYTQQILSGLEYLHAKNTVHRDIKGANILVDPSGV-*IGDFGM 578
            W KG ++G+G+FG VYL  N  +GEM A+K+V +    ++++    + + L  E++ L  L H NIV+Y G E  ++   ++LEYV+GGS+  +++ YG+  E  I+  T Q+L GL YLH+K  +HRD+K  N+L+D  G+  I DFG+
Sbjct: 1175 WMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGI 1324          

BLAST of CX295006 vs. ExPASy Swiss-Prot
Match: AURK_DICDI (Probable serine/threonine-protein kinase aurK OS=Dictyostelium discoideum GN=aurK PE=1 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 3.247e-26
Identity = 69/195 (35.38%), Postives = 105/195 (53.85%), Query Frame = 3

Query:   21 LPPLTISNTCPFSPSYSTATSPSVPRSPGRVENPTSPGSRW-----KKGRLLGRGTFGHVYLGFNSESGEMCAMKEVTLFSDDAKSKESAQQLGQEIALLSRLRHPNIVRYYGSETLDDKLYIYLEYVSGGSIYKILQDYGQLGESAIRSYTQQILSGLEYLHAKNTVHRDIKGANILVDPSG-V*IGDFGMEAY 587
            +PP T +++   S S S+++S S   S     + + P  +W       G+LLG G FGHVYL    +S  + A+K   LF +  ++     QL +EI + S LRHPNI+R +G    D ++++ +E+  GG  +K LQ  G   E    +YT QI   L Y H+K+ +HRDIK  N+L+   G + I DFG   +
Sbjct:   66 IPPTTTASSSSSSSSSSSSSSSSSSSSSSS-SSQSVPKKKWCIDDFDIGKLLGMGRFGHVYLAREKKSQFIVALK--VLFKNQLQTHNIEHQLRREIEIQSHLRHPNILRLFGYFYDDKRVFLIIEFAKGGECFKELQKVGSFNEQTAATYTLQIADALRYCHSKHVIHRDIKPENLLIGVGGEIKIADFGWSVH 257