CX295060

BLAST of CX295060 vs. ExPASy Swiss-Prot
Match: SRC_AVISR (Tyrosine-protein kinase transforming protein Src OS=Avian sarcoma virus (strain rASV1441) GN=V-SRC PE=1 SV=3)

HSP 1 Score: 74.3294 bits (181), Expect = 7.282e-13
Identity = 57/156 (36.54%), Postives = 89/156 (57.05%), Query Frame = 1

Query:    7 LIAELQHRNLVRILGCCVEQGEKILILEYMPNKSLDVYLFDPIKK-----RLLDWEARIRIIQGIAQGLLYLHQYSRLRIIHRDLKASNVLLDKDMNPKISDFGLARMFGGDEL---QGNTKRIVGTYGYMSPEYALDGLFSIKSDVFSFGILMLE 450
            ++ +L+H  LV++     E+   I + EYM   SL  +L   + K     +L+D  A+I      A G+ Y+    R+  +HRDL+A+N+L+ +++  K++DFGLAR+   +E    QG    I  T    +PE AL G F+IKSDV+SFGIL+ E
Sbjct:  313 VMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQI------ASGMAYVE---RMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWT----APEAALYGRFTIKSDVWSFGILLTE 454          

BLAST of CX295060 vs. ExPASy Swiss-Prot
Match: SRC_AVIS2 (Tyrosine-protein kinase transforming protein Src OS=Avian sarcoma virus (strain PR2257) GN=V-SRC PE=3 SV=3)

HSP 1 Score: 74.3294 bits (181), Expect = 7.282e-13
Identity = 57/156 (36.54%), Postives = 89/156 (57.05%), Query Frame = 1

Query:    7 LIAELQHRNLVRILGCCVEQGEKILILEYMPNKSLDVYLFDPIKK-----RLLDWEARIRIIQGIAQGLLYLHQYSRLRIIHRDLKASNVLLDKDMNPKISDFGLARMFGGDEL---QGNTKRIVGTYGYMSPEYALDGLFSIKSDVFSFGILMLE 450
            ++ +L+H  LV++     E+   I + EYM   SL  +L   + K     +L+D  A+I      A G+ Y+    R+  +HRDL+A+N+L+ +++  K++DFGLAR+   +E    QG    I  T    +PE AL G F+IKSDV+SFGIL+ E
Sbjct:  313 VMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQI------ASGMAYVE---RMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWT----APEAALYGRFTIKSDVWSFGILLTE 454          

BLAST of CX295060 vs. ExPASy Swiss-Prot
Match: SHKE_DICDI (Dual specificity protein kinase shkE OS=Dictyostelium discoideum GN=shkE PE=3 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 7.282e-13
Identity = 45/148 (30.41%), Postives = 79/148 (53.38%), Query Frame = 1

Query:    7 LIAELQHRNLVRILGCCVEQGEKILILEYMPNKSLDVYLFDPIKKRLLDWEARIRIIQGIAQGLLYLHQYSRLRIIHRDLKASNVLLDKDMNPKISDFGLARMFGGDELQGNTKRIVGTYGYMSPEYALDGLFSIKSDVFSFGILMLE 450
            ++ ++ H N+V  LG C + G+ +++ E M      +     ++   L    R+++    A G+ +LH      IIHRDLK +N+++ KD   KI DFG +++        + K   GT  YM+PE  +   F+ K+DV+SFG+++ E
Sbjct:  285 IMKQIFHPNVVLCLGACTKPGKVMIVSELMQTDLEKLIHSSEVEPPPL--YERMKMCLDAALGINWLHGICN--IIHRDLKLANLMISKDKTVKIGDFGFSQVIKTGTTLSDQKGPKGTALYMAPEVMMKHEFNEKADVYSFGLILYE 428          

BLAST of CX295060 vs. ExPASy Swiss-Prot
Match: PLK4_DROMO (Serine/threonine-protein kinase PLK4 OS=Drosophila mojavensis GN=SAK PE=3 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 7.282e-13
Identity = 49/151 (32.45%), Postives = 81/151 (53.64%), Query Frame = 1

Query:   13 AELQHRNLVRILGCCVEQGEKILILEYMPNKSLDVYLFDPIKKRLLDWEARIRIIQGIAQGLLYLHQYSRLRIIHRDLKASNVLLDKDMNPKISDFGLARMFGGDELQGNTKRIVGTYGYMSPEYALDGLFSIKSDVFSFGILMLETLSSR 465
            + L+H +++++     +     LILE   N  L  Y+   +K+   + EA   I++ +  GLLYLH ++   I+HRD+  SN+LL KDM+ KI+DFGLA      + +  T  + GT  Y+SPE        + +D++S G ++   L  R
Sbjct:   67 SRLKHPSVLQLYTFFQDANYVYLILELADNGELHRYMNQQMKRPFTEDEAS-SILRQVVDGLLYLHSHN---IMHRDISLSNLLLSKDMHVKIADFGLATQLKRPDERHMT--MCGTPNYISPEVVSHMSHGLPADLWSVGCMLYTLLVGR 211          

BLAST of CX295060 vs. ExPASy Swiss-Prot
Match: NEK3_ORYSJ (Serine/threonine-protein kinase Nek3 OS=Oryza sativa subsp. japonica GN=NEK3 PE=2 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 7.282e-13
Identity = 48/149 (32.21%), Postives = 79/149 (53.02%), Query Frame = 1

Query:    7 LIAELQHRNLVRILGCCVEQGEKI-LILEYMPNKSLDVYLFDPIKKRLLDWEARIRIIQGIAQGLLYLHQYSRLRIIHRDLKASNVLLDKDMNPKISDFGLARMFGGDELQGNTKRIVGTYGYMSPEYALDGLFSIKSDVFSFGILMLE 450
            LIA++++  +V      VE+G  + +++ Y     +     + IKK   ++ +  R+   + Q L+ L       I+HRD+K SN+ L KD N ++ DFGLA++   D+L   T  +VGT  YM PE   D  +  KSD++S G  + E
Sbjct:   54 LIAKVRNPYIVEYKDSWVEKGCYVCIVIGYCEGGDMS----EAIKKANSNYFSEERLCMWLVQLLMALDYLHVNHILHRDVKCSNIFLTKDQNIRLGDFGLAKVLTSDDL---TSSVVGTPSYMCPELLADIPYGSKSDIWSLGCCLYE 195          

BLAST of CX295060 vs. ExPASy Swiss-Prot
Match: JAK2_HUMAN (Tyrosine-protein kinase JAK2 OS=Homo sapiens GN=JAK2 PE=1 SV=2)

HSP 1 Score: 74.3294 bits (181), Expect = 7.282e-13
Identity = 50/151 (33.11%), Postives = 77/151 (50.99%), Query Frame = 1

Query:    7 LIAELQHRNLVRILGCCVEQGEKIL--ILEYMPNKSLDVYLFDPIKKRLLDWEARIRIIQGIAQGLLYLHQYSRLRIIHRDLKASNVLLDKDMNPKISDFGLARMFGGDELQGNTKRI-VGTYGYMSPEYALDGLFSIKSDVFSFGILMLE 450
            ++  LQH N+V+  G C   G + L  I+EY+P  SL  YL     K  +D    ++    I +G+ YL      R IHRDL   N+L++ +   KI DFGL ++   D+     K        + +PE   +  FS+ SDV+SFG+++ E
Sbjct:  901 ILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQK--HKERIDHIKLLQYTSQICKGMEYL---GTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYE 1046          

BLAST of CX295060 vs. ExPASy Swiss-Prot
Match: HCK_MOUSE (Tyrosine-protein kinase HCK OS=Mus musculus GN=Hck PE=1 SV=4)

HSP 1 Score: 74.3294 bits (181), Expect = 7.282e-13
Identity = 66/235 (28.09%), Postives = 111/235 (47.23%), Query Frame = 1

Query:    7 LIAELQHRNLVRILGCCVEQGEKILILEYMPNKSLDVYLFD------PIKKRLLDWEARIRIIQGIAQGLLYLHQYSRLRIIHRDLKASNVLLDKDMNPKISDFGLARMFGGDELQGNTKRIVGTYGYMSPEYALDGLFSIKSDVFSFGILMLE--TLSSRKNTGVYNTDSFNLLGHAWDLWKHERVHELMDPVILQDEIPLPMLMRYVNVALLCVQENAADRPTMSDVVSMISN 687
            L+  LQH  LV+ L   V Q    ++ E+M   SL  +L        P+ K L+D+ A+I      ++G+ ++ Q +    IHRDL+A+N+L+   +  KI+DFGLAR+   +E     +       + +PE    G F+IKSDV+SFGIL++E  T       G+ N +    L H + + + +   E                    N+ + C +    +RPT   + S++ +
Sbjct:  306 LMKSLQHDKLVK-LHAVVSQEPIFIVTEFMAKGSLLDFLKSEEGSKQPLPK-LIDFSAQI------SEGMAFIEQRN---YIHRDLRAANILVSASLVCKIADFGLARIIEDNEYTAR-EGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNCPE-----------------ELYNIMIRCWKNRPEERPTFEYIQSVLDD 511          

BLAST of CX295060 vs. ExPASy Swiss-Prot
Match: FYN_MOUSE (Proto-oncogene tyrosine-protein kinase Fyn OS=Mus musculus GN=Fyn PE=1 SV=3)

HSP 1 Score: 74.3294 bits (181), Expect = 7.282e-13
Identity = 56/154 (36.36%), Postives = 87/154 (56.49%), Query Frame = 1

Query:    7 LIAELQHRNLVRILGCCVEQGEKILILEYMPNKSLDVYLFDPIKKRLLDWEARIRIIQGIAQGLLYLHQYSRLRIIHRDLKASNVLLDKDMNPKISDFGLARMFGGDEL---QGNTKRIVGTYGYMSPEYALDGLFSIKSDVFSFGILMLETLS 459
            ++ +L+H  LV++     E+   I + EYM   SL  +L D  + R L     + +   +A G+ Y+    R+  IHRDL+++N+L+   +  KI+DFGLAR+   +E    QG    I  T    +PE AL G F+IKSDV+SFGIL+ E ++
Sbjct:  317 IMKKLKHDKLVQLYAVVSEEPIYI-VTEYMSKGSLLDFLKDG-EGRALKLPNLVDMAAQVAAGMAYIE---RMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT----APEAALYGRFTIKSDVWSFGILLTELVT 461          

BLAST of CX295060 vs. ExPASy Swiss-Prot
Match: AVR2B_RAT (Activin receptor type-2B OS=Rattus norvegicus GN=Acvr2b PE=1 SV=3)

HSP 1 Score: 74.3294 bits (181), Expect = 7.282e-13
Identity = 63/225 (28.00%), Postives = 109/225 (48.44%), Query Frame = 1

Query:   19 LQHRNLVRIL-----GCCVEQGEKILILEYMPNKSLDVYLFDPIKKRLLDWEARIRIIQGIAQGLLYLHQY--------SRLRIIHRDLKASNVLLDKDMNPKISDFGLARMFGGDELQGNTKRIVGTYGYMSPEYALDGLFS------IKSDVFSFGILMLETLSSRKNTGVYNTDSFNLLGHAWDLWKHERVHELMDPVILQDEIPL--PMLMRYVNVALLCV 630
            ++H NL++ +     GC   + E  LI  +    SL  YL    K  ++ W     + + +++GL YLH+          +  I HRD K+ NVLL  D+   ++DFGLA  F   +  G+T   VGT  YM+PE  L+G  +      ++ D+++ G+++ E L SR        D + +L    ++ +H  + EL + V+ +   P      +++  +A LCV
Sbjct:  239 MKHENLLQFIAAEKRGCSNLEVELWLITAFHDKGSLTDYL----KGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPE-VLEGAINFQRDAFLRIDMYAMGLVLWE-LVSRCKAADGPVDEY-MLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCV 456          

BLAST of CX295060 vs. ExPASy Swiss-Prot
Match: AVR2A_RAT (Activin receptor type-2A OS=Rattus norvegicus GN=Acvr2a PE=1 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 7.282e-13
Identity = 59/223 (26.46%), Postives = 113/223 (50.67%), Query Frame = 1

Query:   19 LQHRNLVRILGCCVEQGEKI-----LILEYMPNKSLDVYLFDPIKKRLLDWEARIRIIQGIAQGLLYLHQY-------SRLRIIHRDLKASNVLLDKDMNPKISDFGLARMFGGDELQGNTKRIVGTYGYMSPEYALDGLFS------IKSDVFSFGILMLETLSSRKNTGVYNTDSFNLLGHAWDLWKHERVHELMDPVILQDEIPL--PMLMRYVNVALLC 627
            ++H N+++ +G   ++G  +     LI  +    SL  +L    K  ++ W     I + +A+GL YLH+         +  I HRD+K+ NVLL  ++   I+DFGLA  F   +  G+T   VGT  YM+PE  L+G  +      ++ D+++ G+++ E L+SR        D + +L    ++ +H  + ++ + V+ + + P+      ++  +A+LC
Sbjct:  241 MKHENILQFIGA-EKRGTSVDVDLWLITAFHEKGSLSDFL----KANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSGGDTHGQVGTRRYMAPE-VLEGAINFQRDAFLRIDMYAMGLVLWE-LASRCTAADGPVDEY-MLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLC 455