CX297861

BLAST of CX297861 vs. ExPASy Swiss-Prot
Match: MBK2_CAEEL (Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2 OS=Caenorhabditis elegans GN=mbk-2 PE=1 SV=1)

HSP 1 Score: 136.346 bits (342), Expect = 1.419e-31
Identity = 72/212 (33.96%), Postives = 121/212 (57.08%), Query Frame = 1

Query:   52 DDKDGHYLFALGENLTSRYKILRKIGEGTFGQVLDCLDRETGETVAIKVVRSIKKYREAAMTEIDVLELLKRYDRSGSR-CVQIRNWFDYRNHICIVFEMLGPSLYDFLRKNNYRPFPVDLVREIGRQLLECVAFMHDLRLIHTDLKPENILFVSPEYLKIPDYKVTARSPTDVNYYKRLPKSSAIKVIDFGSTAYEHQEHNYIVSTRHYRA 684
            DD++G Y   + +++  RY++L+ IG+G+FGQV+   D +  + VA+K+VR+ K++   A  EI +L+ L+R D  G+   + + ++F++RNH CI FE+L  +LY+ +++N ++ F + LVR+    +L C+  +   RLIH DLKPEN+L                          +    S IKVIDFGS+ ++ Q     + +R YRA
Sbjct:  443 DDENGSYQLVVHDHIAYRYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKRFHRQADEEIRILDHLRRQDSDGTHNIIHMLDYFNFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLL-------------------------KQQGRSGIKVIDFGSSCFDDQRIYTYIQSRFYRA 629          

BLAST of CX297861 vs. ExPASy Swiss-Prot
Match: MBK2_CAEBR (Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2 OS=Caenorhabditis briggsae GN=mbk-2 PE=3 SV=2)

HSP 1 Score: 136.346 bits (342), Expect = 1.419e-31
Identity = 72/212 (33.96%), Postives = 121/212 (57.08%), Query Frame = 1

Query:   52 DDKDGHYLFALGENLTSRYKILRKIGEGTFGQVLDCLDRETGETVAIKVVRSIKKYREAAMTEIDVLELLKRYDRSGSR-CVQIRNWFDYRNHICIVFEMLGPSLYDFLRKNNYRPFPVDLVREIGRQLLECVAFMHDLRLIHTDLKPENILFVSPEYLKIPDYKVTARSPTDVNYYKRLPKSSAIKVIDFGSTAYEHQEHNYIVSTRHYRA 684
            DD++G Y   + +++  RY++L+ IG+G+FGQV+   D +  + VA+K+VR+ K++   A  EI +L+ L+R D  G+   + + ++F++RNH CI FE+L  +LY+ +++N ++ F + LVR+    +L C+  +   RLIH DLKPEN+L                          +    S IKVIDFGS+ ++ Q     + +R YRA
Sbjct:  442 DDENGSYQLVVHDHIAYRYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKRFHRQADEEIRILDHLRRQDSDGTHNIIHMLDYFNFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLL-------------------------KQQGRSGIKVIDFGSSCFDDQRIYTYIQSRFYRA 628          

BLAST of CX297861 vs. ExPASy Swiss-Prot
Match: PPK5_SCHPO (Serine/threonine-protein kinase ppk5 OS=Schizosaccharomyces pombe GN=ppk5 PE=1 SV=1)

HSP 1 Score: 134.035 bits (336), Expect = 7.042e-31
Identity = 70/212 (33.02%), Postives = 120/212 (56.60%), Query Frame = 1

Query:   52 DDKDGHYLFALGENLTSRYKILRKIGEGTFGQVLDCLDRETGETVAIKVVRSIKKYREAAMTEIDVLELLKRYDRSG-SRCVQIRNWFDYRNHICIVFEMLGPSLYDFLRKNNYRPFPVDLVREIGRQLLECVAFMHDLRLIHTDLKPENILFVSPEYLKIPDYKVTARSPTDVNYYKRLPKSSAIKVIDFGSTAYEHQEHNYIVSTRHYRA 684
            DD +G Y    G++L  RY+I+  +G+G+FGQVL C+D + G+ VAIKV+++ +K+    + E+ +L+ L   D +  +  ++  + FD+R H+CIV E+LG +L+D +R+NNY+  P+ +V+    Q L+ +  +    +IH DLKPEN+L                            P  + IK+IDFGS+ + +++    + +R YRA
Sbjct:  500 DDDNGDYKAIQGDHLLYRYEIIDTVGKGSFGQVLKCIDHKRGQVVAIKVIKNRQKFHGQTLVEVGILKRLCEADPADKNNVIRYLSHFDFRGHLCIVTELLGSNLFDVIRENNYKGLPLIVVKSFALQGLQALRLLQGQNIIHCDLKPENLLLSH-------------------------PLKARIKLIDFGSSCFYNEKVYTYLQSRFYRA 686          

BLAST of CX297861 vs. ExPASy Swiss-Prot
Match: MNB_DROME (Serine/threonine-protein kinase minibrain OS=Drosophila melanogaster GN=mnb PE=1 SV=2)

HSP 1 Score: 130.954 bits (328), Expect = 5.961e-30
Identity = 75/214 (35.05%), Postives = 115/214 (53.74%), Query Frame = 1

Query:   52 DDKDGHYLFALGENLTSRYKILRKIGEGTFGQVLDCLDRETGETVAIKVVRSIKKYREAAMTEIDVLELLKRYDRSGSR-CVQIRNWFDYRNHICIVFEMLGPSLYDFLRKNNYRPFPVDLVREIGRQLLECVAFMH--DLRLIHTDLKPENILFVSPEYLKIPDYKVTARSPTDVNYYKRLPKSSAIKVIDFGSTAYEHQEHNYIVSTRHYRA 684
            DD +  Y+   GE    RY+I   IG+G+FGQV+   D E    VAIK++++ K +   A  E+ +LE++ R D       V+++  F +RNH+C+VFE+L  +LYD LR  N+R   ++L R+  +QL   + F+   +L +IH DLKPENIL  +P                         K SAIK++DFGS+    Q   + + +R YR+
Sbjct:  146 DDDNHDYIIKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCHVAIKIIKNKKPFLNQAQIEVKLLEMMNRADAENKYYIVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLSTPELNIIHCDLKPENILLCNP-------------------------KRSAIKIVDFGSSCQLGQRIYHYIQSRFYRS 334          

BLAST of CX297861 vs. ExPASy Swiss-Prot
Match: DYR1B_MOUSE (Dual specificity tyrosine-phosphorylation-regulated kinase 1B OS=Mus musculus GN=Dyrk1b PE=1 SV=3)

HSP 1 Score: 130.954 bits (328), Expect = 5.961e-30
Identity = 75/214 (35.05%), Postives = 117/214 (54.67%), Query Frame = 1

Query:   52 DDKDGHYLFALGENLTSRYKILRKIGEGTFGQVLDCLDRETGETVAIKVVRSIKKYREAAMTEIDVLELLKRYDRSGSR-CVQIRNWFDYRNHICIVFEMLGPSLYDFLRKNNYRPFPVDLVREIGRQLLECVAFMH--DLRLIHTDLKPENILFVSPEYLKIPDYKVTARSPTDVNYYKRLPKSSAIKVIDFGSTAYEHQEHNYIVSTRHYRA 684
            DD +  Y+   GE    RY+I   IG+G+FGQV+   D +T E VAIK++++ K +   A  E+ +LEL+ ++D       V ++  F +RNH+C+VFE+L  +LYD LR  ++R   ++L R++ +QL   + F+   +L +IH DLKPENIL  +P                         K SAIK++DFGS+    Q     + +R YR+
Sbjct:   93 DDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNP-------------------------KRSAIKIVDFGSSCQLGQRIYQYIQSRFYRS 281          

BLAST of CX297861 vs. ExPASy Swiss-Prot
Match: DYR1B_HUMAN (Dual specificity tyrosine-phosphorylation-regulated kinase 1B OS=Homo sapiens GN=DYRK1B PE=1 SV=1)

HSP 1 Score: 130.954 bits (328), Expect = 5.961e-30
Identity = 75/214 (35.05%), Postives = 117/214 (54.67%), Query Frame = 1

Query:   52 DDKDGHYLFALGENLTSRYKILRKIGEGTFGQVLDCLDRETGETVAIKVVRSIKKYREAAMTEIDVLELLKRYDRSGSR-CVQIRNWFDYRNHICIVFEMLGPSLYDFLRKNNYRPFPVDLVREIGRQLLECVAFMH--DLRLIHTDLKPENILFVSPEYLKIPDYKVTARSPTDVNYYKRLPKSSAIKVIDFGSTAYEHQEHNYIVSTRHYRA 684
            DD +  Y+   GE    RY+I   IG+G+FGQV+   D +T E VAIK++++ K +   A  E+ +LEL+ ++D       V ++  F +RNH+C+VFE+L  +LYD LR  ++R   ++L R++ +QL   + F+   +L +IH DLKPENIL  +P                         K SAIK++DFGS+    Q     + +R YR+
Sbjct:   93 DDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNP-------------------------KRSAIKIVDFGSSCQLGQRIYQYIQSRFYRS 281          

BLAST of CX297861 vs. ExPASy Swiss-Prot
Match: DYR1A_XENTR (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Xenopus tropicalis GN=dyrk1a PE=2 SV=1)

HSP 1 Score: 130.568 bits (327), Expect = 7.786e-30
Identity = 76/214 (35.51%), Postives = 115/214 (53.74%), Query Frame = 1

Query:   52 DDKDGHYLFALGENLTSRYKILRKIGEGTFGQVLDCLDRETGETVAIKVVRSIKKYREAAMTEIDVLELLKRYDRSGSR-CVQIRNWFDYRNHICIVFEMLGPSLYDFLRKNNYRPFPVDLVREIGRQLLECVAFMH--DLRLIHTDLKPENILFVSPEYLKIPDYKVTARSPTDVNYYKRLPKSSAIKVIDFGSTAYEHQEHNYIVSTRHYRA 684
            DD +  Y+   GE    RY+I   IG+G+FGQV+   DR   E VAIK++++ K +   A  E+ +LEL+ ++D       V ++  F +RNH+C+VFEML  +LYD LR  N+R   ++L R+  +Q+   + F+   +L +IH DLKPENIL  +P                         K SAIK++DFGS+    Q     + +R YR+
Sbjct:  133 DDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRAEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNP-------------------------KRSAIKIVDFGSSCQLGQRIYQYIQSRFYRS 321          

BLAST of CX297861 vs. ExPASy Swiss-Prot
Match: DYR1A_XENLA (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Xenopus laevis GN=dyrk1a PE=2 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 1.017e-29
Identity = 76/214 (35.51%), Postives = 115/214 (53.74%), Query Frame = 1

Query:   52 DDKDGHYLFALGENLTSRYKILRKIGEGTFGQVLDCLDRETGETVAIKVVRSIKKYREAAMTEIDVLELLKRYDRSGSR-CVQIRNWFDYRNHICIVFEMLGPSLYDFLRKNNYRPFPVDLVREIGRQLLECVAFMH--DLRLIHTDLKPENILFVSPEYLKIPDYKVTARSPTDVNYYKRLPKSSAIKVIDFGSTAYEHQEHNYIVSTRHYRA 684
            DD +  Y+   GE    RY+I   IG+G+FGQV+   DR   E VAIK++++ K +   A  E+ +LEL+ ++D       V ++  F +RNH+C+VFEML  +LYD LR  N+R   ++L R+  +Q+   + F+   +L +IH DLKPENIL  +P                         K SAIK++DFGS+    Q     + +R YR+
Sbjct:  133 DDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNP-------------------------KRSAIKIVDFGSSCQLGQRIYQYIQSRFYRS 321          

BLAST of CX297861 vs. ExPASy Swiss-Prot
Match: DYR1A_RAT (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Rattus norvegicus GN=Dyrk1a PE=1 SV=2)

HSP 1 Score: 130.183 bits (326), Expect = 1.017e-29
Identity = 76/214 (35.51%), Postives = 115/214 (53.74%), Query Frame = 1

Query:   52 DDKDGHYLFALGENLTSRYKILRKIGEGTFGQVLDCLDRETGETVAIKVVRSIKKYREAAMTEIDVLELLKRYDRSGSR-CVQIRNWFDYRNHICIVFEMLGPSLYDFLRKNNYRPFPVDLVREIGRQLLECVAFMH--DLRLIHTDLKPENILFVSPEYLKIPDYKVTARSPTDVNYYKRLPKSSAIKVIDFGSTAYEHQEHNYIVSTRHYRA 684
            DD +  Y+   GE    RY+I   IG+G+FGQV+   DR   E VAIK++++ K +   A  E+ +LEL+ ++D       V ++  F +RNH+C+VFEML  +LYD LR  N+R   ++L R+  +Q+   + F+   +L +IH DLKPENIL  +P                         K SAIK++DFGS+    Q     + +R YR+
Sbjct:  141 DDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNP-------------------------KRSAIKIVDFGSSCQLGQRIYQYIQSRFYRS 329          

BLAST of CX297861 vs. ExPASy Swiss-Prot
Match: DYR1A_MOUSE (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Mus musculus GN=Dyrk1a PE=1 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 1.017e-29
Identity = 76/214 (35.51%), Postives = 115/214 (53.74%), Query Frame = 1

Query:   52 DDKDGHYLFALGENLTSRYKILRKIGEGTFGQVLDCLDRETGETVAIKVVRSIKKYREAAMTEIDVLELLKRYDRSGSR-CVQIRNWFDYRNHICIVFEMLGPSLYDFLRKNNYRPFPVDLVREIGRQLLECVAFMH--DLRLIHTDLKPENILFVSPEYLKIPDYKVTARSPTDVNYYKRLPKSSAIKVIDFGSTAYEHQEHNYIVSTRHYRA 684
            DD +  Y+   GE    RY+I   IG+G+FGQV+   DR   E VAIK++++ K +   A  E+ +LEL+ ++D       V ++  F +RNH+C+VFEML  +LYD LR  N+R   ++L R+  +Q+   + F+   +L +IH DLKPENIL  +P                         K SAIK++DFGS+    Q     + +R YR+
Sbjct:  141 DDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNP-------------------------KRSAIKIVDFGSSCQLGQRIYQYIQSRFYRS 329