DY258057

BLAST of DY258057 vs. ExPASy Swiss-Prot
Match: HMCS1_CHICK (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Gallus gallus GN=HMGCS1 PE=1 SV=1)

HSP 1 Score: 342.813 bits (878), Expect = 2.462e-93
Identity = 183/346 (52.89%), Postives = 236/346 (68.21%), Query Frame = 2

Query:    2 EDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCSKYE---KLEG--KQFSLSNADYFMFHSPYNKLVQKSFARSLFNDFMRNASSVDEAAKEKLGPFSTLSG------DESYQSRDLEKVSQQLAKPLYDAKVQPSTLIPKQVGNMYTASLYAALGSLIHNKHSE-LDGQRVVFVSYGSGLTATMFSLKLSEGHHPLSLSNILT 1003
            ED+ S+ LT V  L+E+  +    IGRLEVG+ET+IDKSKS+KT LMQ+FE+ GNTD+EG+D+TNACYGGTAALFN +NW+ESSSWDGRY LVV  D AVYA G ARPTGGA AV MLVG +AP+ FE  LRG+HM HAYDFYKP++ SEYPVVDGKLS  CYL ALD CY    +K     + EG  + F+L++  + +FHSPY KLVQKS AR L NDF+      D+ A+   G FS L        +++Y  RD+EK   + +  L++ K + S L+  Q GNMYT S+Y  L SL+     E L GQR+   SYGSG  AT++S+++++   P S  + +T
Sbjct:   63 EDINSLCLTVVQKLMERNSLSYDCIGRLEVGTETIIDKSKSVKTVLMQLFEESGNTDVEGIDTTNACYGGTAALFNAINWIESSSWDGRYALVVAGDIAVYATGNARPTGGAGAVAMLVGSNAPLIFERGLRGTHMQHAYDFYKPDMVSEYPVVDGKLSIQCYLSALDRCYSVYRNKIHAQWQKEGTDRGFTLNDFGFMIFHSPYCKLVQKSVARLLLNDFLS-----DQNAETANGVFSGLEAFRDVKLEDTYFDRDVEKAFMKASAELFNQKTKASLLVSNQNGNMYTPSVYGCLASLLAQYSPEHLAGQRISEFSYGSGFAATLYSIRVTQDATPGSALDKIT 403          

BLAST of DY258057 vs. ExPASy Swiss-Prot
Match: HMCS1_CRIGR (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Cricetulus griseus GN=HMGCS1 PE=3 SV=1)

HSP 1 Score: 340.887 bits (873), Expect = 9.357e-93
Identity = 175/341 (51.32%), Postives = 238/341 (69.79%), Query Frame = 2

Query:    2 EDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCY----KCLCSKYEKLEG--KQFSLSNADYFMFHSPYNKLVQKSFARSLFNDFMRNASSVDEAAKEKLGPFSTLSGDESYQSRDLEKVSQQLAKPLYDAKVQPSTLIPKQVGNMYTASLYAALGS-LIHNKHSELDGQRVVFVSYGSGLTATMFSLKLSEGHHPLSLSNILT 1003
            ED+ S+ LT V NL+E+  +    IGRLEVG+ET+IDKSKS+K+ LMQ+FE+ GNTDIEG+D+TNACYGGTAA+FN VNW+ESSSWDGRY LVV  D A+YA G ARPTGG  AV +L+GP+AP+ F+  LRG+HM HAYDFYKP++ SEYP+VDGKLS  CYL ALD CY    K + ++++K EG    F+L++  + + HSPY KLVQKS AR   NDF+ + +    +    L  F  +  +++Y  RD+EK   + +  L++ K + S L+  Q GNMYT+S+Y +L S L      +L G+R+   SYGSGL AT++SLK+++   P S  + +T
Sbjct:   63 EDINSLCLTVVQNLMERNSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAIYATGNARPTGGVGAVALLIGPNAPLIFDRGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYRKKIRAQWQK-EGNDNDFTLNDFGFMISHSPYCKLVQKSLARMFLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASSELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKVT 402          

BLAST of DY258057 vs. ExPASy Swiss-Prot
Match: HMCS2_BOVIN (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Bos taurus GN=HMGCS2 PE=2 SV=1)

HSP 1 Score: 339.347 bits (869), Expect = 2.722e-92
Identity = 178/369 (48.24%), Postives = 240/369 (65.04%), Query Frame = 2

Query:    2 EDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCSKYEKLEGKQ------FSLSNADYFMFHSPYNKLVQKSFARSLFNDFMRNASSVDEAAKEKLGPFSTLSGDESYQSRDLEKVSQQLAKPLYDAKVQPSTLIPKQVGNMYTASLYAALGSLI-HNKHSELDGQRVVFVSYGSGLTATMFSLKLSEGHHPLS-LSNILTGYEWWQGSENQGRDFPPENLVEIMKPK 1084
            EDV S+ LT V  L+E+ ++    +GRLEVG+ET+IDKSK++KT LM++F+  GNTDIEG+D+TNACYGGTA+LFN  NW+ESSSWDGRY LVVC D AVY  G ARPTGGA AV MLVGP+AP+  E  LRG+HM + YDFYKP++ SEYP+VDGKLS  CYL ALD CY     K EK + KQ      F+L +  Y +FH+P+ KLVQKS AR +FNDF+  +        + L  F  L  +++Y ++D++K   + +  +++ K + S  +    GNMYT+SLY  L SL+ H+   +L G R+   SYGSGL A+ FS ++S+   P S L  +++     Q      +   PE   EIM  +
Sbjct:  100 EDVNSLCLTVVQQLMERTQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLVGPEAPLVLERGLRGTHMENVYDFYKPDVTSEYPLVDGKLSIQCYLRALDKCYAFYRQKIEK-QWKQAGIDRPFTLDDVQYMIFHTPFCKLVQKSLARLMFNDFLLASGDTQTGIYKGLEAFRGLKLEDTYTNKDVDKAFLKASLNMFNKKTKNSLYLSTYNGNMYTSSLYGCLASLLAHHSAQDLAGSRIGAFSYGSGLAASFFSFRVSQDASPGSPLEKLVSSTSDLQKRLASRKRVSPEEFTEIMNQR 467          

BLAST of DY258057 vs. ExPASy Swiss-Prot
Match: HMCSB_DICDI (Hydroxymethylglutaryl-CoA synthase B OS=Dictyostelium discoideum GN=hgsB PE=3 SV=1)

HSP 1 Score: 338.576 bits (867), Expect = 4.644e-92
Identity = 165/323 (51.08%), Postives = 237/323 (73.37%), Query Frame = 2

Query:    2 EDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCSKYEKL-EGKQFSLSNADYFMFHSPYNKLVQKSFARSLFNDFMRNASSVDEAAKEKLGPFSTLS-GDESYQSRDLEKVSQQLAKPLYDAKVQPSTLIPKQVGNMYTASLYAALGSLIHNKHSELDGQRVVFVSYGSGLTATMFSLKLS 964
            ED++SM++T+V  ++ KY ID + IGRLEVG+ET+IDKSKS+K+ +M +F+++GNT +EGVD+ NACYGGT ALFN + W+ESS WDGRY LVV  D AVY++G ARPTGGA  V ML+GP+A + F+  LRG+HM +  DFYKP+L+SEYP VDGKLS  CYL ALD CY     K+E + +  +FS+ + DY  FHSPYN+LVQKS+AR ++NDF++N ++      + L PF  LS G +SY +  L++++ +L+   +  KV PSTL+ K+ GN Y  S+Y+ + SL+ N  ++L+ ++V+  SYGSGL A++FS +++
Sbjct:   53 EDIVSMAMTSVKMMMSKYSIDYQSIGRLEVGTETIIDKSKSVKSSIMSLFQEYGNTSLEGVDTLNACYGGTNALFNSLQWIESSYWDGRYALVVTGDIAVYSKGAARPTGGAGVVTMLIGPNATLIFDQSLRGTHMENVNDFYKPDLSSEYPYVDGKLSIECYLRALDKCYLEYKKKFESINDDNKFSMDSFDYVCFHSPYNRLVQKSYARLIYNDFLQNPNN---PKYQDLLPFKDLSTGKDSYINSKLDQITLKLSLDDFKTKVNPSTLLSKECGNSYCGSVYSGILSLLSNV-NDLNNKKVLVFSYGSGLAASLFSFRIN 371          

BLAST of DY258057 vs. ExPASy Swiss-Prot
Match: HMCS2_PIG (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Sus scrofa GN=HMGCS2 PE=2 SV=1)

HSP 1 Score: 337.806 bits (865), Expect = 7.921e-92
Identity = 178/369 (48.24%), Postives = 240/369 (65.04%), Query Frame = 2

Query:    2 EDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCSKYEKLEGKQ------FSLSNADYFMFHSPYNKLVQKSFARSLFNDFMRNASSVDEAAKEKLGPFSTLSGDESYQSRDLEKVSQQLAKPLYDAKVQPSTLIPKQVGNMYTASLYAALGSLIHN-KHSELDGQRVVFVSYGSGLTATMFSLKLSEGHHPLS-LSNILTGYEWWQGSENQGRDFPPENLVEIMKPK 1084
            ED+ S+ LT V  L+E+ ++    +G LEVG+ET+IDKSKS+KT LM++F+  GNTDIEG+D+TNACYGGTA+LFN  NWVESS+WDGRY +VVC D AVY  G +RPTGGA AV MLVGP+AP+A E  LRG+HM +AYDFYKPN  SEYP+VDGKLS  CYL ALD CY     K EK + KQ      F+L +  + +FH+P+ KLVQKS AR +F+DF+   S    +  + L  F     +++Y ++D+EK  Q+ +  L++ K +PS  +    GNMYT+SLY  L SL+      +L G R+   SYGSGL A+ +SL++S+   P S L  +++            +   PE   EIM  +
Sbjct:  100 EDINSLCLTVVQRLMERTQLPWDSVGWLEVGTETIIDKSKSVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWVESSAWDGRYAVVVCGDIAVYPRGNSRPTGGAGAVAMLVGPEAPLALERGLRGTHMENAYDFYKPNATSEYPLVDGKLSIQCYLRALDRCYTLYRQKIEK-QWKQAGIERHFTLDDLQFMIFHTPFCKLVQKSLARLMFSDFLLADSDTQSSLYKGLEAFRGQKLEDTYANKDIEKAFQKASLDLFNKKTKPSLYLSLHNGNMYTSSLYGCLASLLSQCSAQDLAGSRIGAFSYGSGLAASFYSLRVSQDASPGSPLEKLVSSVSDLPERLASRKRVSPEEFTEIMNQR 467          

BLAST of DY258057 vs. ExPASy Swiss-Prot
Match: HMCS2_BLAGE (Hydroxymethylglutaryl-CoA synthase 2 OS=Blattella germanica GN=HMGCS-2 PE=2 SV=1)

HSP 1 Score: 334.339 bits (856), Expect = 8.758e-91
Identity = 182/368 (49.46%), Postives = 237/368 (64.40%), Query Frame = 2

Query:    2 EDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCSKYEKL------EGKQFSLSNADYFMFHSPYNKLVQKSFARSLFNDFMRNASSVDEAAKEKLGPFSTLSGDESYQSRDLEKVSQQLAKPLYDAKVQPSTLIPKQVGNMYTASLYAALGSLIHNKH-SELDGQRVVFVSYGSGLTATMFSLKLSEGHHPLS-LSNILTGYEWWQGSENQGRDFPP---ENLVEI 1072
            ED+ S+ LTAV  L+E+  ID   IG LEVG+ET++DK KS+KT LMQ+FE+ GNTD+EG+D+ NACY GTAALFN + W+ESSSWDGRY +VV  D A+YA+    PTGGA A++ML+G +AP+  +  +R SHM HAYDFYKP+L SEYPVVDGKLS  CYL ALD CY   CSK EK       E  +  L   D F+FHSPY KLVQKS AR + NDF++      +     L     L  +++Y  RD+EK+    +K L++ K +PS ++  QVGNMYT SLY  L SL+ ++   EL G+ +   SYGSG  A+MFSL +S    P S LS ++T     +    Q     P   EN++EI
Sbjct:   54 EDINSLCLTAVDKLMERNNIDYNDIGWLEVGTETILDKVKSVKTVLMQLFEESGNTDVEGIDTINACYRGTAALFNALIWIESSSWDGRYAIVVAADIAIYAK-ECSPTGGAGALLMLIGANAPIVIDRGVRASHMKHAYDFYKPDLMSEYPVVDGKLSVQCYLSALDHCYPRFCSKTEKYLKRCGKENTKIDLDYFDAFVFHSPYCKLVQKSVARLVLNDFIQYPEKYQD-----LQQLRNLKFEDTYFDRDIEKIFMDKSKQLFEKKTKPSLMLANQVGNMYTTSLYGGLVSLLISEDIGELAGKCICMFSYGSGFAASMFSLHISTDSSPGSTLSRLVTNLTHIKPQVQQRVKLSPGEFENIMEI 415          

BLAST of DY258057 vs. ExPASy Swiss-Prot
Match: HMCS_YEAST (Hydroxymethylglutaryl-CoA synthase OS=Saccharomyces cerevisiae GN=ERG13 PE=1 SV=1)

HSP 1 Score: 310.457 bits (794), Expect = 1.354e-83
Identity = 165/329 (50.15%), Postives = 215/329 (65.35%), Query Frame = 2

Query:    2 EDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCSK------YEKLEGKQF--SLSNADYFMFHSPYNKLVQKSFARSLFNDFMRNASSVDEAAKEKLGPFSTLSGDESYQSRDLEKVSQQLAKPLYDAKVQPSTLIPKQVGNMYTASLYAALGSLIHNKHS-ELDGQRVVFVSYGSGLTATMFSLKL 961
            ED+ SMSLT ++ L++ Y ID  +IGRLEVG+ET+IDKSKS+K+ LMQ+F +  NTD+EG+D+ NACYGGT ALFN +NW+ES++WDGR  +VVC D A+Y +G ARPTGGA  V M +GPDAP+ F+S +R S+M HAYDFYKP+  SEYP VDG  S TCY+ ALD  YK    K           G      L   DY +FH P  KLV KS+ R L+NDF  N     E   E     +T   DES   +++EK    +AKP +  +V  S ++P   GNMYTAS+YAA  SL++   S +L G+RV   SYGSGL A+++S K+
Sbjct:   95 EDIYSMSLTVLSKLIKSYNIDTNKIGRLEVGTETLIDKSKSVKSVLMQLFGE--NTDVEGIDTLNACYGGTNALFNSLNWIESNAWDGRDAIVVCGDIAIYDKGAARPTGGAGTVAMWIGPDAPIVFDS-VRASYMEHAYDFYKPDFTSEYPYVDGHFSLTCYVKALDQVYKSYSKKAISKGLVSDPAGSDALNVLKYFDYNVFHVPTCKLVTKSYGRLLYNDFRANPQLFPEVDAE----LATRDYDESLTDKNIEKTFVNVAKPFHKERVAQSLIVPTNTGNMYTASVYAAFASLLNYVGSDDLQGKRVGLFSYGSGLAASLYSCKI 416          

BLAST of DY258057 vs. ExPASy Swiss-Prot
Match: HMCS_SCHPO (Hydroxymethylglutaryl-CoA synthase OS=Schizosaccharomyces pombe GN=hcs1 PE=1 SV=1)

HSP 1 Score: 295.434 bits (755), Expect = 4.508e-79
Identity = 158/321 (49.22%), Postives = 210/321 (65.42%), Query Frame = 2

Query:    2 EDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCSKYEKLEGKQ--FSLSNADYFMFHSPYNKLVQKSFARSLFNDFMRNASSVD-EAAKEKLGPFSTLSGDESYQSRDLEKVSQQLAKPLYDAKVQPSTLIPKQVGNMYTASLYAALGSLIHN-KHSELDGQRVVFVSYGSGLTATMFS 952
            ED+ S  LTA++ L+++Y+ID  +IGRLEVG+ET+IDKSKS+K+ LMQ+F    N ++EG+D  NACYGG  ALFN ++W+ESS+WDGR G+VV  D A+YA+G ARPTGGA  V +LVGP+AP+ FE  LRG++M HAYDFYKP+L SEYP VDG  S  CY+ ALD  Y     +     GK     L   DY +FH+P  K VQK++AR L+ D     S+ + E  +E L   STL   +S   + LEK    + K  ++ +V PS   P   GNMYTAS+++ L +L+      EL G+RV   SYGSGL A+ FS
Sbjct:   54 EDIYSFGLTALSQLIKRYQIDISKIGRLEVGTETIIDKSKSVKSVLMQLFGD--NHNVEGIDCVNACYGGVNALFNTIDWIESSAWDGRDGIVVAGDIALYAKGNARPTGGAGCVALLVGPNAPIVFEPGLRGTYMQHAYDFYKPDLTSEYPYVDGHFSLECYVKALDGAYANYNVRDVAKNGKSQGLGLDRFDYCIFHAPTCKQVQKAYARLLYTDSAAEPSNPELEGVRELL---STLDAKKSLTDKALEKGLMAITKERFNKRVSPSVYAPTNCGNMYTASIFSCLTALLSRVPADELKGKRVGAYSYGSGLAASFFS 369          

BLAST of DY258057 vs. ExPASy Swiss-Prot
Match: HMCS_CAEEL (Hydroxymethylglutaryl-CoA synthase OS=Caenorhabditis elegans GN=F25B4.6 PE=2 SV=2)

HSP 1 Score: 208.379 bits (529), Expect = 7.248e-53
Identity = 123/320 (38.44%), Postives = 181/320 (56.56%), Query Frame = 2

Query:    2 EDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVE-SSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKP--NLASEYPVVDGKLSQTCYLMALDTCYKCLCSKYEKLEGKQFSLSNADYFMFHSPYNKLVQKSFARSLFNDF-MRNASSVDEAAKEKLGPFSTLSGDESYQSRDLEKVSQQLAKPLYDAKVQPSTLIPKQVGNMYTASLYAALGSLIHNKHSELDGQRVVFVSYGSGLTATMF 949
            ED++S+SLT    L+E YKI    IG L VG+ET+IDKSKS+KT LM +F   GN+DIEGVD  NAC+GG  AL + ++WV  +   D +  +VV  D A+Y EGPAR TGGA A+  L+ PDA +  + +    HM + +DF+KP   + SEYPVVDG LS + YL A+   Y    SK  +       L++ D    HSP+ K+VQK  A   + D  +R+          KL        DE+ ++   + +  +L+  ++  K  P  +  +++GNMYT SL+A L + +         + ++F +YGSGL + +F
Sbjct:   60 EDIVSISLTVTRKLIETYKISTDSIGCLVVGTETMIDKSKSVKTALMDLFP--GNSDIEGVDIKNACFGGAQALLHAIDWVTVNHPLDKKNAIVVVADIAIYEEGPARCTGGAGAIAFLICPDASIPIDRQFSACHMKNTWDFFKPITPIPSEYPVVDGSLSLSSYLEAVRMTYTYFISKVNRHTTGIDGLNSFDGVFLHSPFTKMVQKGLAVMNYTDSQLRHKQLNGNGVDHKL--------DENDRAGLAKMI--ELSAQVWKEKTDPYLVFNRRIGNMYTPSLFAQLLAYLAADDCVTGEKSILFFAYGSGLASAIF 367