DY258096

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS2_PIG (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Sus scrofa GN=HMGCS2 PE=2 SV=1)

HSP 1 Score: 298.901 bits (764), Expect = 8.871e-81
Identity = 148/263 (56.27%), Postives = 186/263 (70.72%), Query Frame = 1

Query:  220 TMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCNK----YQETGRETNFSFQRLINFWSIPPYNRLGQKN 996
            T  K+VGILA+++YFP   V Q  LE  D    G+YT+GLGQ  M FCS  ED+ S+ LT V  L+E+ ++    +G LEVG+ET+IDKSKS+KT LM++F+  GNTDIEG+D+TNACYGGTA+LFN  NWVESS+WDGRY +VVC D AVY  G +RPTGGA AV MLVGP+AP+A E  LRG+HM +AYDFYKPN  SEYP+VDGKLS  CYL ALD CY     K    +++ G E +F+   L       P+ +L QK+
Sbjct:   49 TWPKDVGILALEVYFPAQYVDQTDLEKFDNVEAGRYTVGLGQTHMGFCSVQEDINSLCLTVVQRLMERTQLPWDSVGWLEVGTETIIDKSKSVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWVESSAWDGRYAVVVCGDIAVYPRGNSRPTGGAGAVAMLVGPEAPLALERGLRGTHMENAYDFYKPNATSEYPLVDGKLSIQCYLRALDRCYTLYRQKIEKQWKQAGIERHFTLDDLQFMIFHTPFCKLVQKS 311          

HSP 2 Score: 21.557 bits (44), Expect = 8.871e-81
Identity = 9/14 (64.29%), Postives = 12/14 (85.71%), Query Frame = 2

Query:  983 LDKKTLARLVFKDF 1024
            L +K+LARL+F DF
Sbjct:  307 LVQKSLARLMFSDF 320          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS2_RAT (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Rattus norvegicus GN=Hmgcs2 PE=2 SV=1)

HSP 1 Score: 298.901 bits (764), Expect = 1.157e-80
Identity = 146/263 (55.51%), Postives = 186/263 (70.72%), Query Frame = 1

Query:  220 TMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCY----KCLCNKYQETGRETNFSFQRLINFWSIPPYNRLGQKN 996
            T  K+VGILA+++YFP   V Q  LE  +    GKYT+GLGQ  M FCS  ED+ S+ LT V  L+E+ K+    +GRLEVG+ET+IDKSK++KT LM++F+  GNTDIEG+D+TNACYGGTA+LFN  NW+ESS WDGRY LVVC D AVY  G  RPTGGA AV ML+GP AP+  E  LRG+HM +AYDFYKPNLASEYP+VDGKLS  CYL ALD CY    + + N++++ G    F+   +       P+ ++ QK+
Sbjct:   49 TWPKDVGILALEVYFPAQYVDQTDLEKFNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERTKLPWDAVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSYWDGRYALVVCGDIAVYPSGNPRPTGGAGAVAMLIGPKAPLVLEQGLRGTHMENAYDFYKPNLASEYPLVDGKLSIQCYLRALDRCYAAYRRKIQNQWKQAGNNQPFTLDDVQYMIFHTPFCKMVQKS 311          

HSP 2 Score: 21.1718 bits (43), Expect = 1.157e-80
Identity = 8/12 (66.67%), Postives = 11/12 (91.67%), Query Frame = 2

Query:  989 KKTLARLVFKDF 1024
            +K+LARL+F DF
Sbjct:  309 QKSLARLMFNDF 320          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCSB_DICDI (Hydroxymethylglutaryl-CoA synthase B OS=Dictyostelium discoideum GN=hgsB PE=3 SV=1)

HSP 1 Score: 298.516 bits (763), Expect = 5.704e-80
Identity = 142/257 (55.25%), Postives = 185/257 (71.98%), Query Frame = 1

Query:  229 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCNKYQETGRETNFSFQRLINFWSIPPYNRLGQKNF 999
            K++GI A+DIYFP T V Q  L+ +D  S GKYTIGLGQ  M+F  + ED++SM++T+V  ++ KY ID + IGRLEVG+ET+IDKSKS+K+ +M +F+++GNT +EGVD+ NACYGGT ALFN + W+ESS WDGRY LVV  D AVY++G ARPTGGA  V ML+GP+A + F+  LRG+HM +  DFYKP+L+SEYP VDGKLS  CYL ALD CY     K++    +  FS           PYNRL QK++
Sbjct:    5 KDIGICAIDIYFPQTYVNQSELKKYDKVSNGKYTIGLGQTNMSFVGDREDIVSMAMTSVKMMMSKYSIDYQSIGRLEVGTETIIDKSKSVKSSIMSLFQEYGNTSLEGVDTLNACYGGTNALFNSLQWIESSYWDGRYALVVTGDIAVYSKGAARPTGGAGVVTMLIGPNATLIFDQSLRGTHMENVNDFYKPDLSSEYPYVDGKLSIECYLRALDKCYLEYKKKFESINDDNKFSMDSFDYVCFHSPYNRLVQKSY 261          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS1_BLAGE (Hydroxymethylglutaryl-CoA synthase 1 OS=Blattella germanica GN=HMGCS-1 PE=2 SV=1)

HSP 1 Score: 298.13 bits (762), Expect = 7.449e-80
Identity = 150/255 (58.82%), Postives = 188/255 (73.73%), Query Frame = 1

Query:  232 NVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCNKYQETGRETNFSFQRLINFWSIPPYNRLGQKN 996
            +VGI+A+++ FP   V Q  LE +D  S GKYT+GLGQ  M FC++ ED+ S+ LT V+ L+E++ I   QIGRLEVG+ET++DKSKS+KT LMQ+F+   NTDIEGVD+ NACYGGT+ALFN ++WVESSSWDGRY LVV  D AVYA+G ARPTGGA AV MLVG +AP+ F+  +R SHM HAYDFYKP+L+S YP VDGKLS  CYL ALD CY+  C+K Q+   E  F  +RL       PY +L QK+
Sbjct:    5 DVGIVALELIFPSQYVDQVDLEVYDNVSAGKYTVGLGQARMGFCTDREDINSLCLTVVSRLMERWSIPYSQIGRLEVGTETLLDKSKSVKTVLMQLFKD--NTDIEGVDTVNACYGGTSALFNAISWVESSSWDGRYALVVAGDIAVYAKGSARPTGGAGAVAMLVGANAPLVFDRGVRSSHMQHAYDFYKPDLSSLYPTVDGKLSIQCYLSALDHCYQLYCSKIQKQLGE-KFDIERLDAVLFHAPYCKLVQKS 256          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS2_BOVIN (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Bos taurus GN=HMGCS2 PE=2 SV=1)

HSP 1 Score: 294.664 bits (753), Expect = 1.649e-79
Identity = 146/263 (55.51%), Postives = 185/263 (70.34%), Query Frame = 1

Query:  220 TMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCNK----YQETGRETNFSFQRLINFWSIPPYNRLGQKN 996
            T  K+VGILAM++YFP   V Q  LE  +    G+YT+GLGQ  M FCS  EDV S+ LT V  L+E+ ++    +GRLEVG+ET+IDKSK++KT LM++F+  GNTDIEG+D+TNACYGGTA+LFN  NW+ESSSWDGRY LVVC D AVY  G ARPTGGA AV MLVGP+AP+  E  LRG+HM + YDFYKP++ SEYP+VDGKLS  CYL ALD CY     K    +++ G +  F+   +       P+ +L QK+
Sbjct:   49 TWPKDVGILAMEVYFPAQYVDQTELEKFNKVEAGRYTVGLGQTQMGFCSVQEDVNSLCLTVVQQLMERTQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLVGPEAPLVLERGLRGTHMENVYDFYKPDVTSEYPLVDGKLSIQCYLRALDKCYAFYRQKIEKQWKQAGIDRPFTLDDVQYMIFHTPFCKLVQKS 311          

HSP 2 Score: 21.557 bits (44), Expect = 1.649e-79
Identity = 9/14 (64.29%), Postives = 12/14 (85.71%), Query Frame = 2

Query:  983 LDKKTLARLVFKDF 1024
            L +K+LARL+F DF
Sbjct:  307 LVQKSLARLMFNDF 320          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS_YEAST (Hydroxymethylglutaryl-CoA synthase OS=Saccharomyces cerevisiae GN=ERG13 PE=1 SV=1)

HSP 1 Score: 282.722 bits (722), Expect = 3.239e-75
Identity = 139/254 (54.72%), Postives = 178/254 (70.08%), Query Frame = 1

Query:  217 KTMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCNKYQETGRETNFSFQRLINFWSIPPYN 978
            KT  +NVGI  + IY P  CV Q  LE  DG S+GKYTIGLGQ  M+F ++ ED+ SMSLT ++ L++ Y ID  +IGRLEVG+ET+IDKSKS+K+ LMQ+F +  NTD+EG+D+ NACYGGT ALFN +NW+ES++WDGR  +VVC D A+Y +G ARPTGGA  V M +GPDAP+ F+S +R S+M HAYDFYKP+  SEYP VDG  S TCY+ ALD  YK    K    G  ++ +    +N      YN
Sbjct:   43 KTRPQNVGIKGIQIYIPTQCVNQSELEKFDGVSQGKYTIGLGQTNMSFVNDREDIYSMSLTVLSKLIKSYNIDTNKIGRLEVGTETLIDKSKSVKSVLMQLFGE--NTDVEGIDTLNACYGGTNALFNSLNWIESNAWDGRDAIVVCGDIAIYDKGAARPTGGAGTVAMWIGPDAPIVFDS-VRASYMEHAYDFYKPDFTSEYPYVDGHFSLTCYVKALDQVYKSYSKKAISKGLVSDPAGSDALNVLKYFDYN 293          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS2_BLAGE (Hydroxymethylglutaryl-CoA synthase 2 OS=Blattella germanica GN=HMGCS-2 PE=2 SV=1)

HSP 1 Score: 276.944 bits (707), Expect = 1.777e-73
Identity = 139/261 (53.26%), Postives = 182/261 (69.73%), Query Frame = 1

Query:  229 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCNKYQE----TGRE-TNFSFQRLINFWSIPPYNRLGQKN 996
            ++VGI+ +++ FP   V Q  LE +D  S GKYT+GLGQ+ M  C++ ED+ S+ LTAV  L+E+  ID   IG LEVG+ET++DK KS+KT LMQ+FE+ GNTD+EG+D+ NACY GTAALFN + W+ESSSWDGRY +VV  D A+YA+    PTGGA A++ML+G +AP+  +  +R SHM HAYDFYKP+L SEYPVVDGKLS  CYL ALD CY   C+K ++     G+E T         F    PY +L QK+
Sbjct:    6 EDVGIIGIEMIFPSLYVDQAELETYDEVSPGKYTMGLGQDKMGVCTDREDINSLCLTAVDKLMERNNIDYNDIGWLEVGTETILDKVKSVKTVLMQLFEESGNTDVEGIDTINACYRGTAALFNALIWIESSSWDGRYAIVVAADIAIYAK-ECSPTGGAGALLMLIGANAPIVIDRGVRASHMKHAYDFYKPDLMSEYPVVDGKLSVQCYLSALDHCYPRFCSKTEKYLKRCGKENTKIDLDYFDAFVFHSPYCKLVQKS 265          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS_SCHPO (Hydroxymethylglutaryl-CoA synthase OS=Schizosaccharomyces pombe GN=hcs1 PE=1 SV=1)

HSP 1 Score: 269.626 bits (688), Expect = 2.837e-71
Identity = 129/219 (58.90%), Postives = 165/219 (75.34%), Query Frame = 1

Query:  229 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCY 885
            K++GI  + +Y P   V+Q ALEAHDG S GKYTIGLG   MAF  + ED+ S  LTA++ L+++Y+ID  +IGRLEVG+ET+IDKSKS+K+ LMQ+F    N ++EG+D  NACYGG  ALFN ++W+ESS+WDGR G+VV  D A+YA+G ARPTGGA  V +LVGP+AP+ FE  LRG++M HAYDFYKP+L SEYP VDG  S  CY+ ALD  Y
Sbjct:    6 KDIGIKGLVLYTPNQYVEQAALEAHDGVSTGKYTIGLGLTKMAFVDDREDIYSFGLTALSQLIKRYQIDISKIGRLEVGTETIIDKSKSVKSVLMQLFGD--NHNVEGIDCVNACYGGVNALFNTIDWIESSAWDGRDGIVVAGDIALYAKGNARPTGGAGCVALLVGPNAPIVFEPGLRGTYMQHAYDFYKPDLTSEYPYVDGHFSLECYVKALDGAY 222          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS_CAEEL (Hydroxymethylglutaryl-CoA synthase OS=Caenorhabditis elegans GN=F25B4.6 PE=2 SV=2)

HSP 1 Score: 214.927 bits (546), Expect = 8.293e-55
Identity = 113/231 (48.92%), Postives = 149/231 (64.50%), Query Frame = 1

Query:  220 TMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVE-SSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKP--NLASEYPVVDGKLSQTCYLMALDTCYKCLCNK 903
            T   +VGI A+++YFP   V Q  LE  +  S GKYTIGLGQ+ M FCS+ ED++S+SLT    L+E YKI    IG L VG+ET+IDKSKS+KT LM +F   GN+DIEGVD  NAC+GG  AL + ++WV  +   D +  +VV  D A+Y EGPAR TGGA A+  L+ PDA +  + +    HM + +DF+KP   + SEYPVVDG LS + YL A+   Y    +K
Sbjct:    9 TPVTDVGIGAIELYFPQNFVDQNDLEKFNNVSSGKYTIGLGQQQMGFCSDNEDIVSISLTVTRKLIETYKISTDSIGCLVVGTETMIDKSKSVKTALMDLFP--GNSDIEGVDIKNACFGGAQALLHAIDWVTVNHPLDKKNAIVVVADIAIYEEGPARCTGGAGAIAFLICPDASIPIDRQFSACHMKNTWDFFKPITPIPSEYPVVDGSLSLSSYLEAVRMTYTYFISK 237