DY259795

BLAST of DY259795 vs. ExPASy Swiss-Prot
Match: SPKUL_DICDI (Bifunctional serine/threonine-protein kinase/NEDD4-like E3 ubiquitin-protein ligase OS=Dictyostelium discoideum GN=DDB_G0276527 PE=3 SV=2)

HSP 1 Score: 77.411 bits (189), Expect = 6.071e-14
Identity = 63/239 (26.36%), Postives = 111/239 (46.44%), Query Frame = 3

Query:  273 PFRPVLLISAGASHSVALLSGNIVCSWGRGEDGQLGHGD-----------------------------------------AEDRLSPTQLSALDGHEI--VSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLF--TPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGT-TEDSLVPQKLQAF--------EEVSIKMVAAGAEHSVAVAEKENSMDGG 827
            P   V+ I+ G  HS+AL     V SWG  +  QLG G+                                         A+ + S +Q S+ + ++I  V ++CG + +   ++  + ++++G GD GRLG G  S L   TP  +++L    +  ++ G  H L +T +G V S+GRN  GQLG+G  +    +P+++Q F        + ++I  V+AG  HS+A+++  ++   G
Sbjct:  241 PSLRVVSIANGGKHSLALTICGKVYSWGGNDSCQLGLGNGSSSSYYSLPQLINFNISYNNNNNNNNNNSTNNNNNNNNDGAQQQFSLSQNSSSNNNKIKIVKLSCGTNRSAVITDKGL-LFTFGRGDHGRLGLGEQSLLMQSTPKLVQSLQGHFIIDMSSGGGHSLVLTNKGLVFSFGRNDQGQLGIGCFSNQQTIPKQIQWFQTSQQQQQQPINIIKVSAGGYHSIAISDNNDTYAWG 478          

HSP 2 Score: 21.1718 bits (43), Expect = 6.071e-14
Identity = 7/12 (58.33%), Postives = 8/12 (66.67%), Query Frame = 2

Query:  815 HGWGRGPYGNLG 850
            + WGR  YG LG
Sbjct:  475 YAWGRSDYGVLG 486          

HSP 3 Score: 70.4774 bits (171), Expect = 1.635e-11
Identity = 45/164 (27.44%), Postives = 83/164 (50.61%), Query Frame = 3

Query:  285 VLLISAGASHSVALLSGNIVCSWGRGEDGQLGHGDAEDRLS-PTQLSALDGHE--------IVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLFTPLPIK------ALHSLRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGTTEDSLVPQK 731
            ++ +S+G  HS+ L +  +V S+GR + GQLG G   ++ + P Q+      +        I+ V+ G  H+ A S++    Y+WG  D+G LG          LP+        + +++   ++ G  H +A++++G + SWG N   +LG  + E+ L P+K
Sbjct:  394 IIDMSSGGGHSLVLTNKGLVFSFGRNDQGQLGIGCFSNQQTIPKQIQWFQTSQQQQQQPINIIKVSAGGYHSIAISDN-NDTYAWGRSDYGVLGTSIDVQGDRNLPVLINSNSVVVDNVKFIDVSSGFQHNVAMSIDGSLYSWGCNAGQRLGFKSDENQLTPKK 556          

BLAST of DY259795 vs. ExPASy Swiss-Prot
Match: ALS2_MOUSE (Alsin OS=Mus musculus GN=Als2 PE=1 SV=2)

HSP 1 Score: 77.0258 bits (188), Expect = 1.747e-13
Identity = 59/187 (31.55%), Postives = 91/187 (48.66%), Query Frame = 3

Query:  279 RPVLLISAGASHSVALLSGNIVCSWG----RGEDGQLGHGDAEDRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLFTPLPIKALHS-------LRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGTTEDSLV-PQKLQAFEEVSIKMVAAGAEHSVAVAE 803
            + VL  + G  H V L     V S+G    + E  ++         SP   SAL GH +++V  G+ H+ A +ES + VY WG    G+    N   +  P P+    S       +R+ Q+ACG+ H LA+++  E+ +WG     QLGL TT   +  PQK++      +  VA GA HS+A+ +
Sbjct:   41 KTVLQAALGVRHGVLLTEDGEVYSFGTLPWKSESAEICPS------SPLLESALVGHHVITVATGSFHSGAVTESGV-VYMWGENAAGQCAVANQQYVPEPSPVSISDSETSPSLAVRILQLACGEEHTLALSLSREIWAWG--TGCQLGLITTTFPVTKPQKVEHLAGRVVLQVACGAFHSLALVQ 218          

HSP 2 Score: 72.7886 bits (177), Expect = 3.295e-12
Identity = 46/123 (37.40%), Postives = 64/123 (52.03%), Query Frame = 3

Query:  279 RPVLLISAGASHSVALLSG--NIVCSWGRGEDGQLGHGDAEDRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLFTPLP--IKALHSLRVKQIACGDSHCL 635
            R V+L    +  + ALL      V +WG+G++GQLGHGD   RL P  +  LDG E++ +  G  H+ A +    QVYSWG   FG+LGH   S+  T +P   K      V  +A G  + L
Sbjct:  499 RTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGSHSLALTAK-SQVYSWGSNTFGQLGH---SEFPTTVPRLSKVSSENGVWSVAAGQDYSL 617          

HSP 3 Score: 70.8626 bits (172), Expect = 1.252e-11
Identity = 39/109 (35.78%), Postives = 60/109 (55.05%), Query Frame = 3

Query:  498 QVYSWGWGDFGRLGHGNSSDLFTPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGTTEDSLVPQKLQAFEEVSIKMVAAGAEHSVAVAEKENSMDG 824
            +V++WG G  G+LGHG+      PL +K L    V  +  G SH LA+T + +V SWG N  GQLG  +   + VP+  +   E  +  VAAG ++S+ + + E+   G
Sbjct:  521 EVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGSHSLALTAKSQVYSWGSNTFGQLG-HSEFPTTVPRLSKVSSENGVWSVAAGQDYSLFLVDTEDFQPG 628          

BLAST of DY259795 vs. ExPASy Swiss-Prot
Match: RCC1_HUMAN (Regulator of chromosome condensation OS=Homo sapiens GN=RCC1 PE=1 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 2.282e-13
Identity = 58/165 (35.15%), Postives = 87/165 (52.73%), Query Frame = 3

Query:  309 SHSVALLSGNIVCSWGRGEDGQLGHGD-AEDRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLFTPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWG--RNQNGQLG-LGTTEDSLVPQKLQAFEEVSIKMVAAGAEHSV 791
            SH        +V + G+G+ GQLG G+   +R  P  +S  +  ++V    G  HT   S+S  QVYS+G  D G LG   S +    +P K     +V Q++ GDSH  A+T +G V  WG  R+ NG +G L   + S+VP ++Q   +V +  VA+G +H V
Sbjct:   26 SHRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPE--DVVQAEAGGMHTVCLSKSG-QVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQL--DVPVVKVASGNDHLV 185          

BLAST of DY259795 vs. ExPASy Swiss-Prot
Match: RCC1_YEAST (Regulator of chromosome condensation OS=Saccharomyces cerevisiae GN=PRP20 PE=1 SV=1)

HSP 1 Score: 76.2554 bits (186), Expect = 2.980e-13
Identity = 58/185 (31.35%), Postives = 92/185 (49.73%), Query Frame = 3

Query:  285 VLLISAGASHSVALLSGNIVCSWG--RGEDGQLGHGDAEDRL--SPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDL----FTPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLG-TTEDSLV---PQKLQAFEEVSIKMVAAGAEHSVAVAE 803
            V+ ++A  + S AL S   V +WG  R  +G LG    + ++  +P ++     + IV +  G DH     E  M V++WG G   +LG             P P    H   VK IA G++HC A+T + ++ SWG NQ GQ G+    ED  +   P++L   + V I+ +AAG  HS+ +++
Sbjct:  167 VVQLAATDNMSCALFSNGEVYAWGTFRCNEGILGFYQDKIKIQKTPWKVPTFSKYNIVQLAPGKDHILFLDEEGM-VFAWGNGQQNQLGRKVMERFRLKTLDPRPFGLRH---VKYIASGENHCFALTKDNKLVSWGLNQFGQCGVSEDVEDGALVTKPKRLALPDNVVIRSIAAGEHHSLILSQ 347          

HSP 2 Score: 69.707 bits (169), Expect = 2.789e-11
Identity = 61/202 (30.20%), Postives = 91/202 (45.05%), Query Frame = 3

Query:  279 RPVLLISAGASHSVALLSGNIVCSWGRGEDGQLGHG-DAEDRL---SPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLG--------------HGNSSDLFTPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGTTEDSL-VPQKLQ--AFEEVSIKMVAAGAEHSVAVAEKENSMD 821
            R V  I++G +H  AL   N + SWG  + GQ G   D ED      P +L+  D   I S+  G  H+   S+    +YS G  D   +G              HG +  +  PLP K  +  + K +A G  H +AV   G   SWG  +   +GLG  ED   VP +++  A ++ +I +V  G + SV+   K +  D
Sbjct:  274 RHVKYIASGENHCFALTKDNKLVSWGLNQFGQCGVSEDVEDGALVTKPKRLALPDNVVIRSIAAGEHHSLILSQDG-DLYSCGRLDMFEVGIPKDNLPEYTYKDVHGKARAV--PLPTKLNNVPKFKSVAAGSHHSVAVAQNGIAYSWGFGETYAVGLGPFEDDTEVPTRIKNTATQDHNIILVGCGGQFSVSGGVKLSDED 472          

BLAST of DY259795 vs. ExPASy Swiss-Prot
Match: RCC1_MOUSE (Regulator of chromosome condensation OS=Mus musculus GN=Rcc1 PE=1 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 3.892e-13
Identity = 57/165 (34.55%), Postives = 86/165 (52.12%), Query Frame = 3

Query:  309 SHSVALLSGNIVCSWGRGEDGQLGHGDAE-DRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLFTPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWG--RNQNGQLG-LGTTEDSLVPQKLQAFEEVSIKMVAAGAEHSV 791
            SH        +V + G+G+ GQLG G++  +R  P  +  L   ++V    G  HT   S+S  QVYS+G  D G LG   S +    +P K     +V Q++ GDSH  A+T +G V  WG  R+ NG +G L   + S+VP ++Q   +  +  VA+G +H V
Sbjct:   26 SHRSHNTEPGLVLTLGQGDVGQLGLGESVLERKKPALVPLLQ--DVVQAEAGGMHTVCLSQSG-QVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTEDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQL--DAPVVKVASGNDHLV 185          

BLAST of DY259795 vs. ExPASy Swiss-Prot
Match: RCC1_MESAU (Regulator of chromosome condensation OS=Mesocricetus auratus GN=RCC1 PE=1 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 5.083e-13
Identity = 56/165 (33.94%), Postives = 87/165 (52.73%), Query Frame = 3

Query:  309 SHSVALLSGNIVCSWGRGEDGQLGHGDAE-DRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLFTPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWG--RNQNGQLG-LGTTEDSLVPQKLQAFEEVSIKMVAAGAEHSV 791
            SH        +V + G+G+ GQLG G++  +R  P  +  L   ++V    G  HT   ++S  QVYS+G  D G LG   S +    +P K     +V Q++ GDSH  A+T +G V  WG  R+ NG +G L   + S+VP ++Q   ++ +  VA+G +H V
Sbjct:   26 SHRSHKTEPGLVLTLGQGDVGQLGLGESVLERKKPALVPLLQ--DVVQAEAGGMHTVCLNQSG-QVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTEDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQL--DMPVVKVASGNDHLV 185          

BLAST of DY259795 vs. ExPASy Swiss-Prot
Match: RPGR_MOUSE (X-linked retinitis pigmentosa GTPase regulator OS=Mus musculus GN=Rpgr PE=1 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 6.475e-13
Identity = 44/121 (36.36%), Postives = 69/121 (57.02%), Query Frame = 3

Query:  444 VSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLFTPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGTTEDSLVPQKLQAFEEV-SIKMVAAGAEHSVAVAE 803
            + ++CG +HT   + +  ++Y +G  ++G+LG G+ + +  P  IKAL   +VK  ACG +H L  T  G V + G N  GQLGLG T+D     ++  F    +IK ++AGA  S A+ E
Sbjct:   38 ICLSCGDEHTAIVTGN-NKLYMFGSNNWGQLGLGSKAAIIKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYAAGGNNEGQLGLGDTDDRDTFHQIVFFTPADTIKQLSAGANTSAALTE 157          

HSP 2 Score: 21.1718 bits (43), Expect = 6.475e-13
Identity = 9/19 (47.37%), Postives = 10/19 (52.63%), Query Frame = 2

Query:  806 GKLHGWGRGPYGNLGLVKK 862
            GKL  WG    G +GL  K
Sbjct:  159 GKLFMWGDNSEGQIGLEDK 177          

HSP 3 Score: 73.1738 bits (178), Expect = 2.523e-12
Identity = 52/187 (27.81%), Postives = 86/187 (45.99%), Query Frame = 3

Query:  288 LLISAGASHSVALLSGNIVCSWGRGEDGQLGHGDAEDRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSD--------LFTPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGTTEDSLVPQKLQAFEEVSIKMVAAGAEHSVAVAEKENSMDG 824
            + +S G  H+  +   N +  +G    GQLG G     + PT + AL   ++    CG +HT   S     VY+ G  + G+LG G++ D         FTP          +KQ++ G +   A+T +G++  WG N  GQ+GL    +  +P ++   + +S   ++ G  HS  V     +MDG
Sbjct:   38 ICLSCGDEHTAIVTGNNKLYMFGSNNWGQLGLGSKAAIIKPTCIKALKPEKVKLAACGRNHTLV-STDTGGVYAAGGNNEGQLGLGDTDDRDTFHQIVFFTPAD-------TIKQLSAGANTSAALTEDGKLFMWGDNSEGQIGLEDKSNVCIPHEVTVGKPIS--WISCGYYHSAFV-----TMDG 209          

HSP 4 Score: 72.7886 bits (177), Expect = 3.295e-12
Identity = 48/179 (26.82%), Postives = 89/179 (49.72%), Query Frame = 3

Query:  279 RPVLLISAGASHSVALLSGNIVCSWGRGEDGQLGHGDA--EDRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSS-DLFTPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGTTE--DSLVPQKLQAFEEVSIKMVAAGAEHSVAVA 800
            +P+  IS G  HS  +     + ++G  E+G+LG  +    +  SP ++  +    ++ V CG  HT   +E    VY++G G FG+LG G    +   P  I+ +   ++  I+CG++H   +T  G + ++G  ++G+LGLG     +   P     F   +++++A G  H +  A
Sbjct:  190 KPISWISCGYYHSAFVTMDGELYTFGEPENGKLGLPNELLMNHRSPQRVLGIP-ERVIQVACGGGHTVVLTEKV--VYAFGLGQFGQLGLGTFLFETSEPKIIERIKDQKICHISCGENHTALMTELGLLYTFGDGRHGKLGLGMENFTNQFFPTLCSNFLRFAVQLIACGGCHMLVFA 365          

HSP 5 Score: 69.707 bits (169), Expect = 2.789e-11
Identity = 53/179 (29.61%), Postives = 91/179 (50.84%), Query Frame = 3

Query:  273 PFRPVLLISAGASHSVALLSGNIVCSWGRGEDGQLGHGDAEDRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLFTPLPIKALH-SLRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGT-TEDSLVPQKLQAFEEVSIKMVAAGAEHSVAVAE 803
            P   +  +SAGA+ S AL     +  WG   +GQ+G  D  +   P +++   G  I  ++CG  H +A+     ++Y++G  + G+LG  N   +    P + L    RV Q+ACG  H + +T E  V ++G  Q GQLGLGT   ++  P+ ++  ++  I  ++ G  H+  + E
Sbjct:  138 PADTIKQLSAGANTSAALTEDGKLFMWGDNSEGQIGLEDKSNVCIPHEVTV--GKPISWISCGYYH-SAFVTMDGELYTFGEPENGKLGLPNELLMNHRSPQRVLGIPERVIQVACGGGHTVVLT-EKVVYAFGLGQFGQLGLGTFLFETSEPKIIERIKDQKICHISCGENHTALMTE 312          

BLAST of DY259795 vs. ExPASy Swiss-Prot
Match: ALS2_HUMAN (Alsin OS=Homo sapiens GN=ALS2 PE=1 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 8.670e-13
Identity = 62/186 (33.33%), Postives = 88/186 (47.31%), Query Frame = 3

Query:  279 RPVLLISAGASHSVALLSG--NIVCSWGRGEDGQLGHGDAEDRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLFTPLPIKALHSLR--VKQIACGDSHCLAVTVEGEVQS---WGRNQNGQLGLGTTED---SLVPQKLQAFEEVSIKMVAAGAEHSVAVAEK 806
            R V+L    +  + ALL      V +WG+G++GQLGHGD   RL P  +  LDG E++ +  G  H+ A +    QVYSWG   FG+LGH   SD  T +P  A  S    V  IA G  + L +    + Q    +   Q+   G    E+   S  P  L   +   I  V AG +  +A+ +K
Sbjct:  505 RTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAK-SQVYSWGSNTFGQLGH---SDFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTEDFQPGLYYSGRQDPTEGDNLPENHSGSKTPVLLSCSKLGYISRVTAGKDSYLALVDK 686          

HSP 2 Score: 69.3218 bits (168), Expect = 3.643e-11
Identity = 47/152 (30.92%), Postives = 76/152 (50.00%), Query Frame = 3

Query:  498 QVYSWGWGDFGRLGHGNSSDLFTPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGTTEDSLVPQKLQAFEEVSIKMVAAGAEHSVAVAEKENSMDGGGALMEIWV**KKDPL----IPE-----KVPTSISKKKNGLVS 926
            +V++WG G  G+LGHG+      PL +K L    V  +  G  H LA+T + +V SWG N  GQLG  +   + VP+  +   E  +  +AAG ++S+ + + E+   G      ++   ++DP     +PE     K P  +S  K G +S
Sbjct:  527 EVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG-HSDFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTEDFQPG------LYYSGRQDPTEGDNLPENHSGSKTPVLLSCSKLGYIS 671          

HSP 3 Score: 68.1662 bits (165), Expect = 8.115e-11
Identity = 56/191 (29.32%), Postives = 90/191 (47.12%), Query Frame = 3

Query:  279 RPVLLISAGASHSVALLSGNIVCSWGR--GEDGQLGHGDAEDRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLFTPLPIKALHS-------LRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGTTEDSLV-PQKLQAFEEVSIKMVAAGAEHSVAVAEKENSMD 821
            + VL  + G  H V L     V S+G      G +    +    SP   +AL G  +++V  G+ H+ A +++ +  Y WG    G+    N   +  P P+    S       +R+ Q+ACG+ H LA+++  E+ +WG     QLGL TT   +  PQK++      +  VA GA HS+A+ +   S D
Sbjct:   41 KTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPS----SPILENALVGQYVITVATGSFHSGAVTDNGV-AYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTLALSISREIWAWG--TGCQLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFHSLALVQCLPSQD 224          

BLAST of DY259795 vs. ExPASy Swiss-Prot
Match: ALS2_PANTR (Alsin OS=Pan troglodytes GN=ALS2 PE=2 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 1.132e-12
Identity = 61/186 (32.80%), Postives = 88/186 (47.31%), Query Frame = 3

Query:  279 RPVLLISAGASHSVALLSG--NIVCSWGRGEDGQLGHGDAEDRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLFTPLPIKALHSLR--VKQIACGDSHCLAVTVEGEVQS---WGRNQNGQLGLGTTED---SLVPQKLQAFEEVSIKMVAAGAEHSVAVAEK 806
            R V+L    +  + ALL      V +WG+G++GQLGHGD   RL P  +  LDG E++ +  G  H+ A +    QVYSWG   FG+LGH   SD  T +P  A  S    V  +A G  + L +    + Q    +   Q+   G    E+   S  P  L   +   I  V AG +  +A+ +K
Sbjct:  505 RTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAK-SQVYSWGSNTFGQLGH---SDFPTTVPRLAKISSENGVWSVAAGRDYSLFLVDTEDFQPGLYYSGRQDPTEGDNLPENHSGSKTPVLLSCSKLGYISRVTAGKDSYLALVDK 686          

HSP 2 Score: 69.707 bits (169), Expect = 2.789e-11
Identity = 48/152 (31.58%), Postives = 76/152 (50.00%), Query Frame = 3

Query:  498 QVYSWGWGDFGRLGHGNSSDLFTPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGTTEDSLVPQKLQAFEEVSIKMVAAGAEHSVAVAEKENSMDGGGALMEIWV**KKDPL----IPE-----KVPTSISKKKNGLVS 926
            +V++WG G  G+LGHG+      PL +K L    V  +  G  H LA+T + +V SWG N  GQLG  +   + VP+  +   E  +  VAAG ++S+ + + E+   G      ++   ++DP     +PE     K P  +S  K G +S
Sbjct:  527 EVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG-HSDFPTTVPRLAKISSENGVWSVAAGRDYSLFLVDTEDFQPG------LYYSGRQDPTEGDNLPENHSGSKTPVLLSCSKLGYIS 671          

HSP 3 Score: 68.5514 bits (166), Expect = 6.213e-11
Identity = 57/191 (29.84%), Postives = 90/191 (47.12%), Query Frame = 3

Query:  279 RPVLLISAGASHSVALLSGNIVCSWGR--GEDGQLGHGDAEDRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLFTPLPIKALHS-------LRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGTTEDSLV-PQKLQAFEEVSIKMVAAGAEHSVAVAEKENSMD 821
            + VL  + G  H V L     V S+G      G +    +    SP   +AL G  +V+V  G+ H+ A +++ +  Y WG    G+    N   +  P P+    S       +R+ Q+ACG+ H LA+++  E+ +WG     QLGL TT   +  PQK++      +  VA GA HS+A+ +   S D
Sbjct:   41 KTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPS----SPILENALVGQYVVTVATGSFHSGAVTDNGV-AYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTLALSISREIWAWG--TGCQLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFHSLALVQCLPSQD 224          

BLAST of DY259795 vs. ExPASy Swiss-Prot
Match: SRGEF_HUMAN (Secretion-regulating guanine nucleotide exchange factor OS=Homo sapiens GN=SERGEF PE=1 SV=2)

HSP 1 Score: 73.559 bits (179), Expect = 1.931e-12
Identity = 52/164 (31.71%), Postives = 82/164 (50.00%), Query Frame = 3

Query:  309 SHSVALLSGNIVCSWGRGEDGQLGHGDAEDRLSPTQLSAL-DGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLGHGNSSDLFTPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGT-TEDSLVPQKLQAFEEVSIKMVAAGAEHSVA 794
            S S A  +   + +WG    GQLG G  ED L P QL+       +  +T G  H+   ++    ++  G    G+LG G++ D+    P K+L    ++Q+ACG    + +T  G+V S G N  GQLG+       +VPQ ++  +E  +  +AAG  H+VA
Sbjct:    6 SASEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGG-DLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKE-KVVCIAAGLRHAVA 167          

HSP 2 Score: 63.929 bits (154), Expect = 3.320e-11
Identity = 54/193 (27.98%), Postives = 80/193 (41.45%), Query Frame = 3

Query:  282 PVLLISAGASHSVALLSGNIVCSWGRGEDGQLGHGDAEDRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFG---RLGHGNSSDLF----TPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWGRNQNGQLGLGTTEDSLVPQKLQA--FEEVSIKMVAAGAEHSVAVAEKENSMDGGGA 833
            P+  ++ G   ++ L     V S G    GQLG      R    Q   L   ++V +  G  H  A + S + V+ WG G      RL  G +  LF     P  +  L + +   +  G  H  ++T  GEV  WG N++GQL         VPQK++A  F+   +  + +G  H VA  E       G A
Sbjct:  102 PIQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHAVAATASGI-VFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLA-NEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTETGKMFTWGRA 292          

HSP 3 Score: 25.409 bits (54), Expect = 3.320e-11
Identity = 9/15 (60.00%), Postives = 10/15 (66.67%), Query Frame = 2

Query:  806 GKLHGWGRGPYGNLG 850
            GK+  WGR  YG LG
Sbjct:  284 GKMFTWGRADYGQLG 298          

HSP 4 Score: 68.1662 bits (165), Expect = 8.115e-11
Identity = 62/185 (33.51%), Postives = 81/185 (43.78%), Query Frame = 3

Query:  279 RPVLLISAGASHSVALLSGNIVCSWGRGEDGQLGHGDAEDRLSPTQLSALDGHEIVSVTCGADHTTAYSESCMQVYSWGWGDFGRLG--HGNSSDLFTPLPIKALHSLRVKQIACGDSHCLAVTVEGEVQSWG--------RNQNGQLGLGTTEDSLVPQKLQAFEEVSIKMVAAGAEHSVAVAE 803
            R V  I+ G  HS  +  G  +   G  +DGQLG G  ED    T   +L G  I  V CG D T   +E+  QV S G   FG+LG  HG       P  I+ LH  +V  IA G  H +A T  G V  WG        R   GQ  L     +  P ++   E      V AG++HS ++ +
Sbjct:   49 RSVRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTEN-GQVLSCGSNSFGQLGVPHG-PRRCVVPQAIE-LHKEKVVCIAAGLRHAVAATASGIVFQWGTGLASCGRRLCPGQT-LPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTD 229