DY262523

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: A1A1A_DANRE (Alcohol dehydrogenase [NADP+] A OS=Danio rerio GN=akr1a1a PE=2 SV=2)

HSP 1 Score: 137.502 bits (345), Expect = 1.008e-34
Identity = 73/180 (40.56%), Postives = 106/180 (58.89%), Query Frame = 3

Query:  117 SSNRRMPVLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKEDFLPMD---FKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDILATAKIPPAANQV 647
            S+ +RMP +GLGT  S        K A+L A+  GYRH D A  Y  E+ +G+A+ E L  G    RD++F+ SKLW +  H + V  A ++SL +L+L Y+DLY+IHWP++   G    P   +  +  D   ++  W AME+  + G  KAIG+SNF+ K++ DIL+ AK  P  NQV
Sbjct:    8 STGQRMPTVGLGTWKS---APGQVKQAVLAALDCGYRHIDCAAAYSNEREVGEALTERLGPGKSLRRDDIFVTSKLWNTKHHPDDVEEACRRSLSDLRLSYLDLYLIHWPMAFGRGDELIPRHPDGTIQYDDTHYRDTWAAMEKLVDQGLAKAIGLSNFNAKQIDDILSIAKHKPVVNQV 184          

HSP 2 Score: 31.9574 bits (71), Expect = 1.008e-34
Identity = 20/76 (26.32%), Postives = 38/76 (50.00%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGARGTIW---GSNRVMECEVLKELQKSKGKTLPRCV*DGHTSKGSV 931
            +VE +P   Q +L   C ++++ + AY+PLG+    W   G   +++   +  + KS  KT  + +   H  +G V
Sbjct:  183 QVECHPYLVQAELVSHCWSRNLTVTAYSPLGSPDRPWVTPGEALLLDDPRVVGIAKSYNKTPAQVIIRWHIQRGVV 258          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: AKCL2_PIG (1,5-anhydro-D-fructose reductase OS=Sus scrofa GN=AKR1E2 PE=1 SV=2)

HSP 1 Score: 134.42 bits (337), Expect = 1.712e-34
Identity = 74/179 (41.34%), Postives = 108/179 (60.34%), Query Frame = 3

Query:  129 RMPVLGLGT-AASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKEDFL---PMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDIL--ATAKIPPAANQV 647
            ++PVLGLGT  A+P   +E  K+AI      GYRHFD A LY  E  +G  I   +  G+++ R++LFI SKLWC+   + LV  A  +SL+ L+L+Y+DLY+IHWP+  KPG  + P+ +   +     DF   WEAME+    G  +AIGVSNF+ ++L  +L     ++ P  NQ+
Sbjct:    3 KIPVLGLGTWQAAPGEVTEAVKVAI----DTGYRHFDCAYLYHNENEVGVGIQAKIDEGVVR-REDLFIVSKLWCTCHKKSLVKSACTRSLKALKLQYLDLYLIHWPMGFKPGEVDLPVDRSGMIVASNTDFLDTWEAMEDLVIEGLVRAIGVSNFNHEQLERLLNKPNLRVKPVTNQI 176          

HSP 2 Score: 34.2686 bits (77), Expect = 1.712e-34
Identity = 18/61 (29.51%), Postives = 35/61 (57.38%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGARGTIWGSNR---VMECEVLKELQKSKGKT 886
            ++E +P   Q KL  FC+++++ + AY PLG      GS+    ++E  V++ + +  GK+
Sbjct:  175 QIECHPYLTQKKLISFCQSRNVSVTAYRPLG------GSSEGVPLLEDPVIQTIAQKHGKS 229          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: DDBX_BOVIN (Dihydrodiol dehydrogenase 3 OS=Bos taurus PE=2 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 5.784e-34
Identity = 84/181 (46.41%), Postives = 113/181 (62.43%), Query Frame = 3

Query:  132 MPVLGLGTAASPFSGSETTKLAILE----AMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIK---KEDFLPMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDIL--ATAKIPPAANQV 647
            +PVLG GT    F+  E  K   LE    A++ G+RH D+A LYQ E+ +G AI   ++ G +K R+++F  SKLW +    ELV PAL+KSL NLQL+Y+DLY+IH+PV+ KPG   FP     K  F  +D    WEA+E+C++ G TK+IGVSNF+ K+L  IL     K  P  NQV
Sbjct:   16 IPVLGFGT----FAPREVPKSEALEVTKFAIEAGFRHIDSAHLYQNEEQVGQAIRSKIADGTVK-REDIFYTSKLWSTSLRPELVRPALEKSLNNLQLDYVDLYIIHFPVALKPGETLFPTDENGKPIFDSVDLCRTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVCNQV 191          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: ALRC_DICDI (Aldose reductase C OS=Dictyostelium discoideum GN=alrC PE=3 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 8.107e-34
Identity = 72/185 (38.92%), Postives = 106/185 (57.30%), Query Frame = 3

Query:  117 SSNRRMPVLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVS---SKP-GSYEFPIKKED----FLPMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDILATAKIPPAANQV 647
            +   ++P +GLGT  S   G      AI  A+K GYRH D A  Y  E+ +G+++ E    G IK R+++F  SKLW S  +  LVV    K++E+L + Y+DLY+IHWP++   S P G    P++ ++      P+  +  W+ ME+   LG  K+IGVSNF+ + L D+L  AKI P  NQV
Sbjct:   20 NDGNQIPSIGLGTYYSENPGEVGD--AINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEGEIK-REDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQV 201          

HSP 2 Score: 38.1206 bits (87), Expect = 8.107e-34
Identity = 17/44 (38.64%), Postives = 30/44 (68.18%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGARGTIWGSNRVME 844
            +VE++P   Q KL+E+C   +I+L AY+PLG     + SN++++
Sbjct:  200 QVEIHPYLTQFKLQEYCDKYEIKLVAYSPLGQGKCDFFSNKILK 243          

HSP 3 Score: 27.7202 bits (60), Expect = 8.107e-34
Identity = 12/33 (36.36%), Postives = 18/33 (54.55%), Query Frame = 1

Query:  880 KDVAQVCLRWAYEQGVCVGVKSFNKEKMKENLN 978
            K VA V  +W  ++G+    KS N  ++ EN N
Sbjct:  251 KSVANVIFKWLNQRGIAAIPKSGNHSRIIENFN 283          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: DIDH_RAT (3-alpha-hydroxysteroid dehydrogenase OS=Rattus norvegicus GN=Akr1c9 PE=1 SV=1)

HSP 1 Score: 134.035 bits (336), Expect = 1.416e-33
Identity = 79/194 (40.72%), Postives = 114/194 (58.76%), Query Frame = 3

Query:   81 MGSISIPDVPLKSSNRRMPVLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKED---FLPMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDIL--ATAKIPPAANQV 647
            M SIS+  V L   N  +PVLG GT        +    A   A+  G+RHFD+A LY+ E+ +G AI   +  G +K R+++F  SKLW +    ELV   L+K+L++ QL+Y+DLY+IH+P++ +PG   FP  +     F  +D    WEAME+C++ G  K+IGVSNF+C++L  IL     K  P  NQV
Sbjct:    1 MDSISLR-VALNDGNF-IPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRSKIEDGTVK-REDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQPGDIFFPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLKYKPVCNQV 191          

HSP 2 Score: 31.5722 bits (70), Expect = 1.416e-33
Identity = 15/38 (39.47%), Postives = 24/38 (63.16%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLG-ARGTIW 823
            +VE +    Q+K+ ++CK+KDI L +Y  LG +R   W
Sbjct:  190 QVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTW 227          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: AK1A1_CRIGR (Alcohol dehydrogenase [NADP+] (Fragment) OS=Cricetulus griseus GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 129.798 bits (325), Expect = 1.426e-33
Identity = 70/173 (40.46%), Postives = 103/173 (59.54%), Query Frame = 3

Query:  138 VLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKEDFLPMD---FKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDILATAKIPPAANQV 647
            ++GLGT  S        K AI  A+ +GYRH D A +Y  E  +G+A+ E +  G    R+ELF+ SKLW +  H E V  AL+K+L +LQLEY+DLY++HWP + + G   FP   +  +  D   +K  W+A+E     G  KA+G+SNF+ +++ DIL+ A + PA  QV
Sbjct:    1 LIGLGTWKS---NPGQVKAAIKYALSVGYRHIDCAAVYGNEIEIGEALKENVGPGKAVPREELFVTSKLWNTKHHPEDVEAALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNDDGTIRYDSTHYKETWKALEALVAKGLVKALGLSNFNSRQIDDILSVASVRPAVLQV 170          

HSP 2 Score: 35.8094 bits (81), Expect = 1.426e-33
Identity = 14/37 (37.84%), Postives = 24/37 (64.86%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGARGTIW 823
            +VE +P   QN+L   C+A+ +++ AY+PLG+    W
Sbjct:  169 QVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAW 205          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: AK1A1_XENLA (Alcohol dehydrogenase [NADP+] OS=Xenopus laevis GN=akr1a1 PE=2 SV=1)

HSP 1 Score: 132.109 bits (331), Expect = 2.308e-33
Identity = 71/179 (39.66%), Postives = 109/179 (60.89%), Query Frame = 3

Query:  120 SNRRMPVLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKEDFLP---MDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDILATAKIPPAANQV 647
            + ++MP++GLGT  S        K A+  A+ +GYRH D A +Y  E  +G+AI E++       R+E+F+ SKLW +  H + V  AL+K+L+ LQL+Y+DLY++HWP + K G   FP   +  +     D+K  W+AME+    G  KAIG+SNF+ +++ DIL+ A + PA  QV
Sbjct:   12 TGQKMPLIGLGTWKS---APGQVKDAVKYALGVGYRHIDCAFVYGNETEVGEAIKESVGPDKGLKREEVFVTSKLWNNKHHPDDVECALRKTLQELQLDYLDLYLMHWPYAFKRGDQVFPQNPDGSVQYDLTDYKDTWKAMEKLVEKGLAKAIGLSNFNKRQMDDILSIATVKPAVLQV 187          

HSP 2 Score: 30.8018 bits (68), Expect = 2.308e-33
Identity = 13/37 (35.14%), Postives = 21/37 (56.76%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGARGTIW 823
            +VE +P   QN+L   C++  + L  Y+PLG+    W
Sbjct:  186 QVECHPYLAQNELIACCRSHGLVLTGYSPLGSPDRSW 222          

HSP 3 Score: 22.3274 bits (46), Expect = 2.308e-33
Identity = 10/29 (34.48%), Postives = 16/29 (55.17%), Query Frame = 1

Query:  889 AQVCLRWAYEQGVCVGVKSFNKEKMKENL 975
            AQ+ LRW  ++ V    KS    ++ +NL
Sbjct:  248 AQILLRWQVQRRVVTIPKSVTPARILQNL 276          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: CRO_RANTE (Rho crystallin OS=Rana temporaria PE=2 SV=3)

HSP 1 Score: 122.479 bits (306), Expect = 2.309e-33
Identity = 66/177 (37.29%), Postives = 104/177 (58.76%), Query Frame = 3

Query:  132 MPVLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKED---FLPMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDIL--ATAKIPPAANQV 647
            MP+LGLGT ASP       + A+  A+ +GYRH D A +   E  +G+ I   +S G +K R+++F   KLWC+    E+V   L++SL ++ ++Y+DL+++HWPVS KP     P  K+    +  +D  + WEA+E  ++ G  +++GVSNF+ ++L  IL     K  P  NQV
Sbjct:   17 MPILGLGTYASPHVPKSLAEEAVKIAIDVGYRHIDCAFITGNEMHIGNGIRSKISDGTVK-REDIFYTGKLWCTYFSPEMVRKGLERSLRDVGMDYLDLFLMHWPVSLKPSGASDPSDKDKPFIYDNVDLCATWEALEARKDAGLVRSLGVSNFNRRQLERILNKPGLKYKPVCNQV 192          

HSP 2 Score: 34.2686 bits (77), Expect = 2.309e-33
Identity = 15/32 (46.88%), Postives = 21/32 (65.62%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGA 808
            +VE +    QNKL  +CK+KDI L  Y+ LG+
Sbjct:  191 QVECHVYLNQNKLHSYCKSKDIVLVTYSVLGS 222          

HSP 3 Score: 28.4906 bits (62), Expect = 2.309e-33
Identity = 11/39 (28.21%), Postives = 24/39 (61.54%), Query Frame = 1

Query:  859 RIAEVKGKDVAQVCLRWAYEQGVCVGVKSFNKEKMKENL 975
            ++A    +  A++ +R+  ++G+ V  KSF   ++K+NL
Sbjct:  244 KVAAKYNRTSAEIAMRFILQKGIVVLAKSFTPARIKQNL 282          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: ALRB_DICDI (Aldose reductase B OS=Dictyostelium discoideum GN=alrB PE=3 SV=2)

HSP 1 Score: 130.183 bits (326), Expect = 3.131e-33
Identity = 74/189 (39.15%), Postives = 111/189 (58.73%), Query Frame = 3

Query:  111 LKSSNRRMPVLGLGTAASPFSGSETTKL--AILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPV----SSKPGSYEFPIKKEDFLP----MDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDILATAKIPPAANQV 647
            L      +P++GLGT    ++G++  ++  A+  A+K GYRH D A +Y  E+ +G A+ E  + G IK R+++F  SKLW S  H  LV    +K+LE+L LEY+DLY+IHWP+    +   G+   P++  D  P    +  +  W+ ME+    G  K+IGVSNF+ + L D+L  AKI PA NQV
Sbjct:   10 LNDDIHHIPMIGLGT----YNGAKVGEVGDAVKVALKSGYRHIDGAAIYMNEKEIGHALKEVFAEGEIK-REDIFYVSKLWNSCHHASLVRKHCEKTLEDLGLEYLDLYLIHWPIAFENADPSGTTTQPLRDSDGEPVLAAVSIRETWQEMEKLVEYGLVKSIGVSNFNVQNLVDLLTYAKIKPAINQV 193          

HSP 2 Score: 34.2686 bits (77), Expect = 3.131e-33
Identity = 20/63 (31.75%), Postives = 30/63 (47.62%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGARGTIWGSNRVMECEVLKELQKSKGKTLPRCV 901
            +VE++P   Q  L+ FC    I L AY+PLG      G   ++  E LK +     KT+   +
Sbjct:  192 QVEVHPYLSQPNLKYFCDRYGIVLTAYSPLGQ-----GKCDLLSNETLKSIADKHNKTVANVI 249          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: AK1D1_MOUSE (3-oxo-5-beta-steroid 4-dehydrogenase OS=Mus musculus GN=Akr1d1 PE=2 SV=1)

HSP 1 Score: 124.79 bits (312), Expect = 4.075e-33
Identity = 69/182 (37.91%), Postives = 109/182 (59.89%), Query Frame = 3

Query:  117 SSNRRMPVLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKEDFLPMD---FKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDIL--ATAKIPPAANQV 647
            S    +P++GLGT + P      T +A+  A+  GYRH D A +Y  E  +G+AI E ++ G +K R+E+F   KLW ++    +V+PAL+++L+ L+L+YIDLY+I  P++ KPG   +P  +   +  D     + WEA+E C++ G  K++GVSNF+ ++L  IL     K  P  NQV
Sbjct:   13 SDGNNIPLIGLGTYSDPRPVPGKTYVAVKTAIDEGYRHIDGAYVYHNEHEVGEAIREKIAEGKVK-REEIFYCGKLWNTEHVPSMVLPALERTLKALKLDYIDLYIIELPMAFKPGKEIYPRDENGRIIYDKTNLCATWEALEACKDAGLVKSLGVSNFNRRQLELILNKPGLKYKPVTNQV 193          

HSP 2 Score: 39.2762 bits (90), Expect = 4.075e-33
Identity = 26/77 (33.77%), Postives = 40/77 (51.95%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLG-ARGTIW---GSNRVMECEVLKELQKSKGKTLPRCV*DGHTSKGSV 931
            +VE +P + Q KL +FC+  DI + A++PLG  R   W    S  ++  E+L  L K   KT  + V   +  +G V
Sbjct:  192 QVECHPYFTQTKLLKFCQQHDIVIVAHSPLGTCRNPSWVNVSSPPLLNDELLTSLGKKYNKTQAQIVLRFNIQRGIV 268