DY262523

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: AK1D1_HUMAN (3-oxo-5-beta-steroid 4-dehydrogenase OS=Homo sapiens GN=AKR1D1 PE=1 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 4.075e-33
Identity = 71/189 (37.57%), Postives = 114/189 (60.32%), Query Frame = 3

Query:  105 VPLKSSNRRMPVLGLGTAASPFS---GSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKED---FLPMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDIL--ATAKIPPAANQV 647
            +PL   N  +P++GLGT + P S   G+  T + +  A+  GYRH D A +YQ E  +G+AI E ++ G ++ R+++F   KLW ++   E+V P L+++L  LQL+Y+DLY+I  P++ KPG   +P  +     +   +  + WEAME C++ G  K++GVSNF+ ++L  IL     K  P +NQV
Sbjct:   10 IPLSDGNS-IPIIGLGTYSEPKSTPKGACATSVKV--AIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVR-REDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQV 194          

HSP 2 Score: 41.5874 bits (96), Expect = 4.075e-33
Identity = 27/77 (35.06%), Postives = 42/77 (54.55%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLG-ARGTIW---GSNRVMECEVLKELQKSKGKTLPRCV*DGHTSKGSV 931
            +VE +P + Q KL +FC+  DI + AY+PLG +R  IW    S  +++  +L  L K   KT  + V   +  +G V
Sbjct:  193 QVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVV 269          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: AK1CD_MESAU (Aldo-keto reductase family 1 member C13 OS=Mesocricetus auratus GN=AKR1C13 PE=1 SV=1)

HSP 1 Score: 132.494 bits (332), Expect = 4.076e-33
Identity = 75/181 (41.44%), Postives = 108/181 (59.67%), Query Frame = 3

Query:  132 MPVLGLGTAASPFSGSETTKLAILEAMKL----GYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKEDFL---PMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDIL--ATAKIPPAANQV 647
            +P LG GT    +   E  K   +EA  L    GYRH DTA  YQ E+ +G AI   +  GI+K R+++FI +KLWC+    ELV P+L+K    LQLE++DL+++H+PV  K G  +FP+ ++  L    +DF + WEA+E+  + G  K+IGVSNF+ ++L  IL     K  P  NQV
Sbjct:   16 IPALGFGT----YKPIEVPKSKAMEAANLAIGVGYRHIDTAYAYQIEEEIGQAIQSNIKAGIVK-REDMFITTKLWCTCFQPELVRPSLEKXXXKLQLEHVDLFIMHYPVPMKAGDNDFPLDEQGKLLLDTVDFCATWEALEKXXDAGLVKSIGVSNFNMRQLERILNKPGLKYKPVCNQV 191          

HSP 2 Score: 31.5722 bits (70), Expect = 4.076e-33
Identity = 14/33 (42.42%), Postives = 22/33 (66.67%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGAR 811
            +VE +    Q+KL ++CK+KDI L A+  LG +
Sbjct:  190 QVECHVYNNQSKLLDYCKSKDIVLVAFGALGTQ 222          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: GCY_YEAST (Protein GCY OS=Saccharomyces cerevisiae GN=GCY1 PE=1 SV=1)

HSP 1 Score: 125.946 bits (315), Expect = 5.311e-33
Identity = 76/190 (40.00%), Postives = 110/190 (57.89%), Query Frame = 3

Query:  117 SSNRRMPVLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYE------FPIKKE-----DFLPMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDILATA--KIPPAANQV 647
            ++  ++P +GLGT  S  + +     A+L A+K GYRH DTA +Y+ E  +G AI ++   G+   R+E+F+ +KLWC+  H   V  AL +SL+ L L+Y+DLY++HWP    P   +       P KK+     D    +F   WE M+E    G TKA+GVSNFS   L D+LA+   K+ PAANQV
Sbjct:   15 NTGAQIPQIGLGTWQSKENDAYK---AVLTALKDGYRHIDTAAIYRNEDQVGQAIKDS---GV--PREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQV 194          

HSP 2 Score: 37.7354 bits (86), Expect = 5.311e-33
Identity = 23/73 (31.51%), Postives = 38/73 (52.05%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGARGTIWGSNRVMECEVLKELQKSKGKTLPRCV*DGHTSKGSV 931
            +VE++PL  Q++L  FCK+K I + AY+PLG+         +++  V+ E+ K         V   H  +G V
Sbjct:  193 QVEIHPLLPQDELINFCKSKGIVVEAYSPLGSTDA-----PLLKEPVILEIAKKNNVQPGHVVISWHVQRGYV 260          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: CRO_RANCA (Rho crystallin OS=Rana catesbeiana PE=1 SV=2)

HSP 1 Score: 120.168 bits (300), Expect = 6.577e-33
Identity = 64/177 (36.16%), Postives = 104/177 (58.76%), Query Frame = 3

Query:  132 MPVLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKED---FLPMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDIL--ATAKIPPAANQV 647
            MP+LGLGT A+P       + A+  A+ +GYRH D A +   E  +G+ I   +S G +K R+++F   KLWC+    ++V   L++SL ++ ++Y+DL+++HWPVS KP     P  K+    +  +D  + WEA+E  ++ G  +++GVSNF+ ++L  IL     K  P  NQV
Sbjct:   17 MPILGLGTYAAPDVPKSLAEEAVKTAIDVGYRHIDCAFITGNEMHIGNGIRSKISDGTVK-REDIFYTGKLWCTYFSPDMVRKGLERSLRDVGMDYLDLFLMHWPVSLKPSGASDPSDKDKPFIYDNVDLCATWEALEARKDAGLVRSLGVSNFNRRQLERILNKPGLKYKPVCNQV 192          

HSP 2 Score: 34.2686 bits (77), Expect = 6.577e-33
Identity = 15/32 (46.88%), Postives = 21/32 (65.62%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGA 808
            +VE +    QNKL  +CK+KDI L  Y+ LG+
Sbjct:  191 QVECHVYLNQNKLHSYCKSKDIVLVTYSVLGS 222          

HSP 3 Score: 29.261 bits (64), Expect = 6.577e-33
Identity = 13/39 (33.33%), Postives = 24/39 (61.54%), Query Frame = 1

Query:  859 RIAEVKGKDVAQVCLRWAYEQGVCVGVKSFNKEKMKENL 975
            +IA    +  A+V +R+  ++G+ V  KSF   ++K+NL
Sbjct:  244 KIAAKYNRTSAEVAMRFILQKGIVVLAKSFTPARIKQNL 282          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: ALRA_DICDI (Aldose reductase A OS=Dictyostelium discoideum GN=alrA PE=2 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 1.529e-32
Identity = 67/179 (37.43%), Postives = 109/179 (60.89%), Query Frame = 3

Query:  117 SSNRRMPVLGLGTAASPFSGSETTKL--AILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKEDFLPMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDILATAKIPPAANQV 647
            SS  ++P++G GT  +     ETT +  A+  A+  GYRH D A +Y  E+ +G+A  +  +T     R+++FI SKLW +   +E V PAL+++L +L L+Y+DLY++HWPV+ +  S +          +  +  WE ME+  + G  K+IG+SNF+ + L ++L+ A+I PAANQV
Sbjct:    8 SSGHKIPLVGFGTWKA-----ETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAANQV 181          

HSP 2 Score: 36.965 bits (84), Expect = 1.529e-32
Identity = 19/60 (31.67%), Postives = 33/60 (55.00%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGARGTIWGSNRVMECEVLKELQKSKGKTLP 892
            +VE++P   Q +L++FC   +I L AY+PL       G+   ++ E +  + K   KT+P
Sbjct:  180 QVELHPFLSQPELKKFCDKHNIHLTAYSPL-------GNGAFVDNEEVGAIAKKYNKTIP 232          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: AK1CL_RAT (Aldo-keto reductase family 1 member C21 OS=Rattus norvegicus GN=Akr1c21 PE=2 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 1.861e-32
Identity = 75/177 (42.37%), Postives = 109/177 (61.58%), Query Frame = 3

Query:  132 MPVLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKED---FLPMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDIL--ATAKIPPAANQV 647
            +PVLG GTA          K     A+  G+ HFD+A +Y TE  +G+AI E ++ G  + R+++F  SKLWC+  H ELV  +L+ SL+ LQL+Y+DLY+IH+P++ KPG   FP+ +     F  +D  + WEAME+C++ G  K+IGVSNF+ ++L  IL     K  P  NQV
Sbjct:   16 IPVLGFGTAMPSELPKSKAKEVTKIAIDAGFHHFDSAFVYNTEDHVGEAIREKIANGTTR-REDIFYTSKLWCTSLHPELVRSSLECSLKKLQLDYVDLYLIHFPMALKPGDENFPVDEHGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQV 191          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: AK1BA_HUMAN (Aldo-keto reductase family 1 member B10 OS=Homo sapiens GN=AKR1B10 PE=1 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 1.989e-32
Identity = 77/184 (41.85%), Postives = 105/184 (57.07%), Query Frame = 3

Query:  117 SSNRRMPVLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKED-----FLPMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDIL--ATAKIPPAANQV 647
            S+  +MP++GLGT  SP       K A+  A+  GYRH D A +YQ E  +G+AI E +    +K R++LFI SKLW +   R LV  A +K+L++L+L Y+D+Y+IHWP   K G   FP  K+D          F   WEAMEE  + G  KA+GVSNFS  ++  +L     K  P  NQV
Sbjct:    8 STKAKMPIVGLGTWKSPLG---KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVK-REDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP--KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQV 185          

HSP 2 Score: 37.3502 bits (85), Expect = 1.989e-32
Identity = 20/61 (32.79%), Postives = 32/61 (52.46%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGARGTIWGSNR---VMECEVLKELQKSKGKT 886
            +VE +P   Q KL ++C +K I + AY+PLG+    W       ++E   +KE+     KT
Sbjct:  184 QVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKT 244          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: ALD2_CRIGR (Aldose reductase-related protein 2 OS=Cricetulus griseus GN=AKR1B8 PE=1 SV=3)

HSP 1 Score: 122.094 bits (305), Expect = 3.374e-32
Identity = 75/184 (40.76%), Postives = 105/184 (57.07%), Query Frame = 3

Query:  117 SSNRRMPVLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKED-----FLPMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDIL--ATAKIPPAANQV 647
            S+  +MP++GLGT  SP       K A+  A+  GYRH D A  Y  E  +G+AI E +    ++ R++LFI SKLW +   R+L+  A QK+L +L+L+Y+DLY+IHWP   +PG   FP  K+D        + F   WE MEE  + G  KA+GVSNF+  ++  IL     K  P  NQV
Sbjct:    8 STKAKMPIVGLGTWQSP---PGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQEKIKEKAVR-REDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFP--KDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPVTNQV 185          

HSP 2 Score: 38.891 bits (89), Expect = 3.374e-32
Identity = 21/61 (34.43%), Postives = 32/61 (52.46%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGARGTIWGSNR---VMECEVLKELQKSKGKT 886
            +VE +P   Q KL E+C +K I + AY+PLG+    W       ++E   +KE+     KT
Sbjct:  184 QVECHPYLTQEKLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSLLEDPKIKEIAAKHKKT 244          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: YDG7_SCHPO (Uncharacterized oxidoreductase C26F1.07 OS=Schizosaccharomyces pombe GN=SPAC26F1.07 PE=2 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 4.392e-32
Identity = 71/176 (40.34%), Postives = 105/176 (59.66%), Query Frame = 3

Query:  129 RMPVLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKEDFLPMD---FKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDILATAKIPPAANQV 647
            ++P LGLGT  S       TK A+  A++ GYRH D A +Y  E  +GD I E+   G+   R ++++ SKLWC+    E V  AL+K+L++L+L+Y+D Y+IHWPVS K G  +FP  K+  L  +    +  W+AME+    G  + IG+SNF+   L  IL  AK+ PA +Q+
Sbjct:   23 KIPGLGLGTWRSE---PNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIKES---GV--PRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQM 190          

HSP 2 Score: 36.5798 bits (83), Expect = 4.392e-32
Identity = 19/59 (32.20%), Postives = 36/59 (61.02%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGARGTIWGSN--RVMECEVLKELQKSKGK 883
            ++E++P   Q +  E  K   I + AY+P G + TI+ S   +++E E ++++ KSKG+
Sbjct:  189 QMELHPFLPQTEFVEKHKKLGIHVTAYSPFGNQNTIYESKIPKLIEHETIQKIAKSKGE 247          

BLAST of DY262523 vs. ExPASy Swiss-Prot
Match: ALD2_MOUSE (Aldose reductase-related protein 2 OS=Mus musculus GN=Akr1b8 PE=1 SV=2)

HSP 1 Score: 120.168 bits (300), Expect = 2.563e-31
Identity = 71/182 (39.01%), Postives = 103/182 (56.59%), Query Frame = 3

Query:  117 SSNRRMPVLGLGTAASPFSGSETTKLAILEAMKLGYRHFDTATLYQTEQPLGDAIAEALSTGIIKSRDELFIASKLWCSDAHRELVVPALQKSLENLQLEYIDLYVIHWPVSSKPGSYEFPIKKEDFL---PMDFKSVWEAMEECQNLGYTKAIGVSNFSCKKLGDIL--ATAKIPPAANQV 647
            S+  +MP++GLGT  SP       K A+  A+  GYRH D A  Y  E  +G+AI E +    ++ R++LFI SKLW +   ++L+  A QK+L +L+L+Y+DLY+IHWP   +PG   FP   +  +      F   WE MEE  + G  KA+GVSNF+  ++  +L     K  P  NQV
Sbjct:    8 STKAKMPIVGLGTWKSP---PNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEKAVQ-REDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQV 185          

HSP 2 Score: 34.2686 bits (77), Expect = 2.563e-31
Identity = 14/32 (43.75%), Postives = 22/32 (68.75%), Query Frame = 2

Query:  713 KVEMNPLWQQNKLREFCKAKDIQLAAYAPLGA 808
            +VE +P   Q KL ++C +K I + AY+PLG+
Sbjct:  184 QVECHPYLTQEKLIQYCHSKGISVTAYSPLGS 215          

HSP 3 Score: 23.8682 bits (50), Expect = 2.563e-31
Identity = 13/40 (32.50%), Postives = 22/40 (55.00%), Query Frame = 1

Query:  856 ERIAEVKGKDVAQVCLRWAYEQGVCVGVKSFNKEKMKENL 975
            + IA    K  AQV +R+  ++ V V  KS    +++EN+
Sbjct:  235 KEIAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENI 274