FC923827

BLAST of FC923827 vs. ExPASy Swiss-Prot
Match: TOP1_ARATH (DNA topoisomerase 1 OS=Arabidopsis thaliana GN=TOP1 PE=1 SV=1)

HSP 1 Score: 194.126 bits (492), Expect = 6.033e-49
Identity = 96/123 (78.05%), Postives = 105/123 (85.37%), Query Frame = 3

Query:    3 DTVGCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGDVAVKIDVISVQTKRLLL 371
            DTVGCCTLKVGNVECIPPNK+KFDFLGKDSIQYVNTVEVE  VYKAIGQFQ GK + DDLFD+LDT+KLNAHLKEL+PGLTAKVFRTYNASITLD ML++ T DGDV  KI V     K + +
Sbjct:  651 DTVGCCTLKVGNVECIPPNKIKFDFLGKDSIQYVNTVEVEPLVYKAIGQFQAGKSKTDDLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKANKEVAI 773          

HSP 2 Score: 186.808 bits (473), Expect = 9.632e-47
Identity = 93/121 (76.86%), Postives = 107/121 (88.43%), Query Frame = 2

Query:  341 YQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNXKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCK 703
            YQ+ANKEVAIICNHQRTVSKTH AQ+ +LT +IE+LK VLK+L+ +LDRAKKGKPPL + SDGK+ R+L P A E+K+AQ + KIEKMERDM TKEDLKTVALGTSKINYLDPRITVAWCK
Sbjct:  764 YQKANKEVAIICNHQRTVSKTHGAQIEKLTARIEELKEVLKELKTNLDRAKKGKPPL-EGSDGKKIRSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCK 883          

BLAST of FC923827 vs. ExPASy Swiss-Prot
Match: TOP1_CAEEL (DNA topoisomerase 1 OS=Caenorhabditis elegans GN=top-1 PE=2 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 2.651e-47
Identity = 68/124 (54.84%), Postives = 79/124 (63.71%), Query Frame = 3

Query:    3 DTVGCCTLKVGNVECIPPNKL------------KFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGD-VAVKI 335
            DTVGCC+L+V +++     KL            +FDFLGKDSI+Y N V VE  VYK +  F  GK  +DDLFD+LDTA LN HL+ LM GLT KVFRTYNASITL   L K T   D VA KI
Sbjct:  542 DTVGCCSLRVEHIKLFDSAKLNEDDKKEKEFVVEFDFLGKDSIRYFNRVSVEKRVYKNLKIFMEGKAPSDDLFDRLDTATLNDHLRSLMDGLTVKVFRTYNASITLQEQLIKLTNPKDNVAAKI 665          

HSP 2 Score: 92.4337 bits (228), Expect = 2.651e-47
Identity = 48/121 (39.67%), Postives = 69/121 (57.02%), Query Frame = 2

Query:  341 YQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNXKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCK 703
            Y RAN++VAI+CNHQR VSK     M +L +KI+D K  +K+    L                K  R    E  ++K  +   +++K++     K++ K +ALGTSK+NY+DPRITVAWCK
Sbjct:  668 YNRANRQVAILCNHQRAVSKGFDESMQKLEQKIKDKKKEVKEAEAAL----------------KSARGAEKEKAQKKYDRLKEQLKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCK 772          

BLAST of FC923827 vs. ExPASy Swiss-Prot
Match: TOP1_CERAE (DNA topoisomerase 1 OS=Cercopithecus aethiops GN=TOP1 PE=2 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 1.694e-46
Identity = 61/117 (52.14%), Postives = 78/117 (66.67%), Query Frame = 3

Query:    3 DTVGCCTLKVGNVECIPPNK-----LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKI 335
            DTVGCC+L+V ++   P        ++FDFLGKDSI+Y N V VE  V+K +  F   K+  DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D ++  KI
Sbjct:  502 DTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKI 618          

HSP 2 Score: 96.6709 bits (239), Expect = 1.694e-46
Identity = 56/121 (46.28%), Postives = 71/121 (58.68%), Query Frame = 2

Query:  341 YQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNXKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCK 703
            Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL  AK     +MKD+  K+      +A++R   Q    + K+E     +E+ K +ALGTSK+NYLDPRITVAWCK
Sbjct:  621 YNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRDLKSAK-ADAKVMKDAKTKKVVESKKKAVQRLEEQ----LMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736          

BLAST of FC923827 vs. ExPASy Swiss-Prot
Match: TOP1_HUMAN (DNA topoisomerase 1 OS=Homo sapiens GN=TOP1 PE=1 SV=2)

HSP 1 Score: 110.923 bits (276), Expect = 2.208e-46
Identity = 61/117 (52.14%), Postives = 78/117 (66.67%), Query Frame = 3

Query:    3 DTVGCCTLKVGNVECIPPNK-----LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKI 335
            DTVGCC+L+V ++   P        ++FDFLGKDSI+Y N V VE  V+K +  F   K+  DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D ++  KI
Sbjct:  500 DTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKI 616          

HSP 2 Score: 96.2857 bits (238), Expect = 2.208e-46
Identity = 56/121 (46.28%), Postives = 71/121 (58.68%), Query Frame = 2

Query:  341 YQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNXKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCK 703
            Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL  AK     +MKD+  K+      +A++R   Q    + K+E     +E+ K +ALGTSK+NYLDPRITVAWCK
Sbjct:  619 YNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADARRDLKSAK-ADAKVMKDAKTKKVVESKKKAVQRLEEQ----LMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 734          

BLAST of FC923827 vs. ExPASy Swiss-Prot
Match: TOP1_RAT (DNA topoisomerase 1 OS=Rattus norvegicus GN=Top1 PE=2 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 4.887e-46
Identity = 61/117 (52.14%), Postives = 77/117 (65.81%), Query Frame = 3

Query:    3 DTVGCCTLKVGNVECIPPNK-----LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKI 335
            DTVGCC+L+V ++   P        ++FDF GKDSI+Y N V VE  V+K +  F   K+  DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D +V  KI
Sbjct:  502 DTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKI 618          

HSP 2 Score: 97.4413 bits (241), Expect = 4.887e-46
Identity = 56/121 (46.28%), Postives = 71/121 (58.68%), Query Frame = 2

Query:  341 YQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNXKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCK 703
            Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL  AK     +MKD+  K+      +A++R   Q    + K+E     +E+ K +ALGTSK+NYLDPRITVAWCK
Sbjct:  621 YNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARKDLKSAK-ADAKVMKDAKTKKVVESKKKAVQRLEEQ----LMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736          

BLAST of FC923827 vs. ExPASy Swiss-Prot
Match: TOP1_MOUSE (DNA topoisomerase 1 OS=Mus musculus GN=Top1 PE=1 SV=2)

HSP 1 Score: 108.612 bits (270), Expect = 6.369e-46
Identity = 61/117 (52.14%), Postives = 77/117 (65.81%), Query Frame = 3

Query:    3 DTVGCCTLKVGNVECIPPNK-----LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKI 335
            DTVGCC+L+V ++   P        ++FDF GKDSI+Y N V VE  V+K +  F   K+  DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D +V  KI
Sbjct:  502 DTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKI 618          

HSP 2 Score: 97.0561 bits (240), Expect = 6.369e-46
Identity = 56/121 (46.28%), Postives = 71/121 (58.68%), Query Frame = 2

Query:  341 YQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNXKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCK 703
            Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL  AK     +MKD+  K+      +A++R   Q    + K+E     +E+ K +ALGTSK+NYLDPRITVAWCK
Sbjct:  621 YNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAK-ADAKVMKDAKTKKVVESKKKAVQRLEEQ----LMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736          

BLAST of FC923827 vs. ExPASy Swiss-Prot
Match: TOP1M_HUMAN (DNA topoisomerase I, mitochondrial OS=Homo sapiens GN=TOP1MT PE=2 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 1.841e-45
Identity = 64/117 (54.70%), Postives = 77/117 (65.81%), Query Frame = 3

Query:    3 DTVGCCTLKVGNVECIPP-----NKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGT-GDGDVAVKI 335
            DTVGCC+L+V +V+  P      + ++FDFLGKD I+Y N V VE PVYK +  F   K   DDLFD+L T  LN HL+ELM GLTAKVFRTYNASITL   L   T  +  +A KI
Sbjct:  336 DTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKI 452          

HSP 2 Score: 87.4261 bits (215), Expect = 1.841e-45
Identity = 49/121 (40.50%), Postives = 67/121 (55.37%), Query Frame = 2

Query:  341 YQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNXKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCK 703
            Y RAN+ VAI+CNHQR    T    M  L  KI+  K  + + R +L RA+          DGK +  L  E   R + +   ++ ++      KE+ K VALGTSK+NYLDPRI++AWCK
Sbjct:  455 YNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKA---QGDGKSRSVL--EKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCK 570          

BLAST of FC923827 vs. ExPASy Swiss-Prot
Match: TOP1_CRIGR (DNA topoisomerase 1 OS=Cricetulus griseus GN=TOP1 PE=2 SV=1)

HSP 1 Score: 106.301 bits (264), Expect = 3.120e-45
Identity = 60/117 (51.28%), Postives = 76/117 (64.96%), Query Frame = 3

Query:    3 DTVGCCTLKVGNVECIPPNK-----LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKI 335
            DTV CC+L+V ++   P        ++FDF GKDSI+Y N V VE  V+K +  F   K+  DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D +V  KI
Sbjct:  502 DTVSCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKI 618          

HSP 2 Score: 97.0561 bits (240), Expect = 3.120e-45
Identity = 56/121 (46.28%), Postives = 71/121 (58.68%), Query Frame = 2

Query:  341 YQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNXKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCK 703
            Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL  AK     +MKD+  K+      +A++R   Q    + K+E     +E+ K +ALGTSK+NYLDPRITVAWCK
Sbjct:  621 YNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAK-ADAKVMKDAKTKKVVESKKKAVQRLEEQ----LMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCK 736          

BLAST of FC923827 vs. ExPASy Swiss-Prot
Match: TOP1_DICDI (DNA topoisomerase 1 OS=Dictyostelium discoideum GN=top1 PE=3 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 8.985e-45
Identity = 54/100 (54.00%), Postives = 70/100 (70.00%), Query Frame = 3

Query:    3 DTVGCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNK 302
            DTVGCC+L+V +++    N +  DFLGKDS++Y+NTV++    YK +  F  GKK  D LFD L   +LN HLK+ M GL+AKVFRTYNASITL   L+K
Sbjct:  593 DTVGCCSLRVEHIKLESNNTITLDFLGKDSMRYLNTVQIREDAYKVLKTFVKGKKPTDLLFDSLTVTQLNNHLKKQMTGLSAKVFRTYNASITLQKELDK 692          

HSP 2 Score: 91.6633 bits (226), Expect = 8.985e-45
Identity = 58/157 (36.94%), Postives = 84/157 (53.50%), Query Frame = 2

Query:  341 YQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGK------------PPLM-------KDSDGKR--------------KRNLAPEA---LERKMAQTNXKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCK 703
            Y R N+EVAI+CNHQ+   K  +  MS++ EKI++L+ +    R+ + +  K +            P L+       KD D ++              K    P+A   ++ K+A+   +I+K E     K++LKTVALGTSKINYLDPRITVAWCK
Sbjct:  708 YNRCNREVAILCNHQKAPPKNLAETMSKIDEKIQELRDLQDLCRIKIGKTPKSQQEDIESREAERLPKLIQLAITNKKDKDKEKTDKEISFDVKAAFEKSRTLPDAKGKIKEKIAKYEEQIKKQEILKTGKDELKTVALGTSKINYLDPRITVAWCK 864          

BLAST of FC923827 vs. ExPASy Swiss-Prot
Match: TOP1M_PANTR (DNA topoisomerase I, mitochondrial OS=Pan troglodytes GN=TOP1MT PE=2 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 9.020e-45
Identity = 63/117 (53.85%), Postives = 77/117 (65.81%), Query Frame = 3

Query:    3 DTVGCCTLKVGNVECIPP-----NKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGT-GDGDVAVKI 335
            DTVGCC+L+V +V+  P      + ++FDFLGKD I+Y N V VE PVYK +  F   K   D+LFD+L T  LN HL+ELM GLTAKVFRTYNASITL   L   T  +  +A KI
Sbjct:  336 DTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMESKGPRDNLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKI 452          

HSP 2 Score: 87.4261 bits (215), Expect = 9.020e-45
Identity = 49/121 (40.50%), Postives = 67/121 (55.37%), Query Frame = 2

Query:  341 YQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNXKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCK 703
            Y RAN+ VAI+CNHQR    T    M  L  KI+  K  + + R +L RA+          DGK +  L  E   R + +   ++ ++      KE+ K VALGTSK+NYLDPRI++AWCK
Sbjct:  455 YNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKA---QGDGKSRSVL--EKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCK 570