FC924887

BLAST of FC924887 vs. ExPASy Swiss-Prot
Match: FTHS_ARATH (Formate--tetrahydrofolate ligase OS=Arabidopsis thaliana GN=THFS PE=2 SV=1)

HSP 1 Score: 397.512 bits (1020), Expect = 4.211e-110
Identity = 197/243 (81.07%), Postives = 209/243 (86.01%), Query Frame = 3

Query:   48 SKTVRKLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPASITWRKVMDVNDRFLRKIT 776
            S + RKL+VVSPVPADIDIANSVEPLHISEIA++LN+ P HYDLYGKYKAKVLLS  DEL+G  DGYYVVVGGITPTPLGEGKSTTTVGLCQALGA+LDKKVVTCLRQPSQGPTFGIK       YSQVIPMDEFNLHLTGDIH               RIFHE SQSDKALFNRLCPPNKEG+RSFS+IMFRRL KLGISKT PE+LTPEEI +FARLDIDPASITWR+VMDVNDRFLRKIT
Sbjct:    2 SSSTRKLEVVSPVPADIDIANSVEPLHISEIAKDLNINPLHYDLYGKYKAKVLLSAFDELQGQEDGYYVVVGGITPTPLGEGKSTTTVGLCQALGAYLDKKVVTCLRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITASNNLLAAAIDTRIFHETSQSDKALFNRLCPPNKEGKRSFSDIMFRRLTKLGISKTSPEELTPEEIKKFARLDIDPASITWRRVMDVNDRFLRKIT 244          

BLAST of FC924887 vs. ExPASy Swiss-Prot
Match: FTHS_SPIOL (Formate--tetrahydrofolate ligase OS=Spinacia oleracea PE=1 SV=3)

HSP 1 Score: 390.578 bits (1002), Expect = 5.147e-108
Identity = 191/244 (78.28%), Postives = 210/244 (86.07%), Query Frame = 3

Query:   45 SSKTVRKLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPASITWRKVMDVNDRFLRKIT 776
            SSKTVRKL+V +PVPADIDIAN+VEPLHI++IA +LNL P HYDLYGKYKAKVLLSVLDE++ + DGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIK       YSQVIPMDEFNLHLTGDIH               R+FHE++QSDKALFNRLCPPNKEG+R+F NIM RRLKKLGI KT P+DLTPEE+ +FARLDIDP SITWR+VMDVNDRFLRKI+
Sbjct:    4 SSKTVRKLEVATPVPADIDIANAVEPLHIADIAADLNLSPRHYDLYGKYKAKVLLSVLDEVQETQDGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITASNNLLAAAIDTRMFHESTQSDKALFNRLCPPNKEGKRTFCNIMHRRLKKLGIDKTNPDDLTPEEVTKFARLDIDPDSITWRRVMDVNDRFLRKIS 247          

BLAST of FC924887 vs. ExPASy Swiss-Prot
Match: C1TC_HUMAN (C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens GN=MTHFD1 PE=1 SV=3)

HSP 1 Score: 281.182 bits (718), Expect = 4.398e-75
Identity = 146/237 (61.60%), Postives = 172/237 (72.57%), Query Frame = 3

Query:   66 LQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPASITWRKVMDVNDRFLRKIT 776
            L + +PVP+DIDI+ S +P  I ++A+E+ L     +LYG+ KAKVLLS L+ L+   DG YVVV GITPTPLGEGKSTTT+GL QALGA L + V  C+RQPSQGPTFGIK       YSQVIPM+EFNLHLTGDIH               RIFHE +Q+DKALFNRL  P+  G R FS+I  RRLK+LGI KT P  LT EEINRFARLDIDP +ITW++V+D NDRFLRKIT
Sbjct:  310 LNLKTPVPSDIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSALERLKHRPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLV-PSVNGVRRFSDIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRFLRKIT 545          

BLAST of FC924887 vs. ExPASy Swiss-Prot
Match: C1TC_RAT (C-1-tetrahydrofolate synthase, cytoplasmic OS=Rattus norvegicus GN=Mthfd1 PE=1 SV=3)

HSP 1 Score: 279.641 bits (714), Expect = 1.280e-74
Identity = 145/238 (60.92%), Postives = 171/238 (71.85%), Query Frame = 3

Query:   63 KLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPASITWRKVMDVNDRFLRKIT 776
            KL + +PVP+DI I+ S +P  I  +A+E+ L     +LYG+ KAKVLLS LD L+   DG YVVV GITPTPLGEGKSTTT+GL QALGA L + V  C+RQPSQGPTFGIK       YSQVIPM+EFNLHLTGDIH               RIFHE +Q+DKALFNRL  P+  G R FS+I  RRL++LGI KT P  LT +EINRFARLDIDP +ITW++V+D NDRFLRKIT
Sbjct:  309 KLNLKTPVPSDIAISRSCKPKLIGNLAREIGLLTEEVELYGETKAKVLLSALDRLKHQPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLHQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLV-PSVNGVRKFSDIQIRRLRRLGIEKTDPAALTDDEINRFARLDIDPETITWQRVLDTNDRFLRKIT 545          

BLAST of FC924887 vs. ExPASy Swiss-Prot
Match: C1TC_PONAB (C-1-tetrahydrofolate synthase, cytoplasmic OS=Pongo abelii GN=MTHFD1 PE=2 SV=3)

HSP 1 Score: 279.256 bits (713), Expect = 1.671e-74
Identity = 146/237 (61.60%), Postives = 171/237 (72.15%), Query Frame = 3

Query:   66 LQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPASITWRKVMDVNDRFLRKIT 776
            L + +P P+DIDI+ S +P  I ++A+E+ L     +LYG+ KAKVLLS L+ L+   DG YVVV GITPTPLGEGKSTTTVGL QALGA L + V  C+RQPSQGPTFGIK       YSQVIPM+EFNLHLTGDIH               RIFHE +Q+DKALFNRL  P+  G R FS+I  RRLK+LGI KT P  LT EEINRFARLDIDP +ITW++V+D NDRFLRKIT
Sbjct:  310 LNLKTPDPSDIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSALERLKHRPDGKYVVVTGITPTPLGEGKSTTTVGLVQALGAHLYQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAFTAANNLVAAAIDARIFHELTQTDKALFNRLV-PSVNGVRKFSDIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRFLRKIT 545          

BLAST of FC924887 vs. ExPASy Swiss-Prot
Match: C1TC_MOUSE (C-1-tetrahydrofolate synthase, cytoplasmic OS=Mus musculus GN=Mthfd1 PE=1 SV=3)

HSP 1 Score: 278.87 bits (712), Expect = 2.183e-74
Identity = 145/238 (60.92%), Postives = 171/238 (71.85%), Query Frame = 3

Query:   63 KLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPASITWRKVMDVNDRFLRKIT 776
            KL + +PVP+DI I+ S +P  I  +A+E+ L     +LYG+ KAKVLLS LD L+   DG YVVV GITPTPLGEGKSTTT+GL QALGA L + V  C+RQPSQGPTFGIK       YSQVIPM+EFNLHLTGDIH               RIFHE +Q+DKALFNRL  P+  G R FS+I  RRL++LGI KT P  LT +EINRFARLDIDP +ITW++V+D NDRFLRKIT
Sbjct:  309 KLNLKTPVPSDIAISRSCKPKLIGNLAREIGLLTEEVELYGETKAKVLLSALDRLKYQPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLRQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLV-PSVNGIRKFSDIQIRRLRRLGIEKTDPTTLTDDEINRFARLDIDPETITWQRVLDTNDRFLRKIT 545          

BLAST of FC924887 vs. ExPASy Swiss-Prot
Match: C1TM_HUMAN (Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens GN=MTHFD1L PE=1 SV=1)

HSP 1 Score: 267.314 bits (682), Expect = 6.572e-71
Identity = 137/238 (57.56%), Postives = 168/238 (70.59%), Query Frame = 3

Query:   63 KLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPASITWRKVMDVNDRFLRKIT 776
            KLQ +SPVP+DI+I+    P  +  +A+E+ L  +  ++YGK KAKV LSVL+ L+  ADG YV+V GITPTPLGEGKST T+GL QAL A L+     CLRQPSQGPTFG+K       Y+QVIPM+EFNLHLTGDIH               RI HE +Q+DKAL+NRL  P   G R FS I   RLKKLGI+KT P  LT EE+++FARLDIDP++ITW++V+D NDRFLRKIT
Sbjct:  352 KLQPLSPVPSDIEISRGQTPKAVDVLAKEIGLLADEIEIYGKSKAKVRLSVLERLKDQADGKYVLVAGITPTPLGEGKSTVTIGLVQALTAHLNVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAITAANNLLAAAIDTRILHENTQTDKALYNRLV-PLVNGVREFSEIQLARLKKLGINKTDPSTLTEEEVSKFARLDIDPSTITWQRVLDTNDRFLRKIT 588          

BLAST of FC924887 vs. ExPASy Swiss-Prot
Match: C1TM_BOVIN (Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Bos taurus GN=MTHFD1L PE=2 SV=2)

HSP 1 Score: 264.618 bits (675), Expect = 4.260e-70
Identity = 135/238 (56.72%), Postives = 169/238 (71.01%), Query Frame = 3

Query:   63 KLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPASITWRKVMDVNDRFLRKIT 776
            KLQ +SPVP+DI+I+ +  P  +  +A+E+ L  +  ++YGK KAKV LS+L+ L+  ADG YV+V GITPTPLGEGKST T+GL QAL A L+     CLRQPSQGPTFG+K       Y+QVIPM+EFNLHLTGDIH               RI HE +Q+DKAL+NRL  P+  G R FS I   RLK+LGI+KT P  LT EE+ +FARLDIDP++ITW++V+D NDRFLRKIT
Sbjct:  349 KLQPLSPVPSDIEISRAQTPKAVEILAKEIGLLADEIEIYGKSKAKVRLSLLERLKDQADGKYVLVAGITPTPLGEGKSTVTIGLVQALTAHLNVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAITAANNLLAAAIDARILHENTQTDKALYNRLV-PSVNGVREFSKIQLARLKRLGINKTDPSALTEEEMRKFARLDIDPSTITWQRVVDTNDRFLRKIT 585          

BLAST of FC924887 vs. ExPASy Swiss-Prot
Match: C1TM_MOUSE (Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Mus musculus GN=Mthfd1l PE=1 SV=2)

HSP 1 Score: 263.077 bits (671), Expect = 1.239e-69
Identity = 135/238 (56.72%), Postives = 165/238 (69.33%), Query Frame = 3

Query:   63 KLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPASITWRKVMDVNDRFLRKIT 776
            KLQ +SPVP+DI+I+    P  +  +A+E+ L  +  ++YGK KAKV LS+L+ L+   DG YV+V GITPTPLGEGKST T+GL QAL A L      CLRQPSQGPTFG+K       Y+QVIPM+EFNLHLTGDIH               RI HE++Q+DKAL+NRL  P   G R FS I   RLKKLGI KT P  LT EE+ +FARL+IDPA+ITW++V+D NDRFLRKIT
Sbjct:  351 KLQPLSPVPSDIEISRGQTPKAVDVLAKEIGLLADEIEIYGKSKAKVQLSLLERLKDQTDGKYVLVAGITPTPLGEGKSTVTIGLVQALTAHLKVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAITAANNLLAAAIDTRILHESTQTDKALYNRLV-PLVNGVREFSEIQLSRLKKLGIHKTDPSTLTEEEVRKFARLNIDPATITWQRVLDTNDRFLRKIT 587          

BLAST of FC924887 vs. ExPASy Swiss-Prot
Match: C1TC_SCHPO (C-1-tetrahydrofolate synthase, cytoplasmic OS=Schizosaccharomyces pombe GN=SPBC839.16 PE=2 SV=1)

HSP 1 Score: 254.988 bits (650), Expect = 3.375e-67
Identity = 132/241 (54.77%), Postives = 166/241 (68.88%), Query Frame = 3

Query:   54 TVRKLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPASITWRKVMDVNDRFLRKIT 776
            T+  L++ +PVP+DI+IA S  P +I ++A E+ +  +  + YG +KAKV L +L  L    DG+YVVV GITPTP GEGKST T GL QAL + LDK  + C+RQPSQGPTFGIK       YSQ IPM+EFNLHLTGDIH               R+FHE +QSD AL+ RL    K  +R F+ +MFRRLKKLGI KT PE+LT EE  +FARLDI+P++I+W + +DVNDRFLRKIT
Sbjct:  300 TLLPLKLQTPVPSDIEIARSQTPKNIGDLASEIGIAKSELEFYGSHKAKVNLEILQRLAHRRDGHYVVVTGITPTPFGEGKSTLTAGLVQAL-SNLDKLAIACVRQPSQGPTFGIKGGAAGGGYSQFIPMEEFNLHLTGDIHAITAATNLLAAAIDTRMFHENTQSDAALYKRLTLV-KGNKREFAPVMFRRLKKLGIDKTNPEELTEEEQRKFARLDIEPSTISWNRTLDVNDRFLRKIT 538