FC925003

BLAST of FC925003 vs. ExPASy Swiss-Prot
Match: FTHS_ARATH (Formate--tetrahydrofolate ligase OS=Arabidopsis thaliana GN=THFS PE=2 SV=1)

HSP 1 Score: 376.326 bits (965), Expect = 9.523e-104
Identity = 186/233 (79.83%), Postives = 198/233 (84.98%), Query Frame = 2

Query:   50 SKTVRKLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPPSITWKRVMD 748
            S + RKL+VVSPVPADIDIANSVEPLHISEIA++LN+ P HYDLYGKYKAKVLLS  DEL+G  DGYYVVVGGITPTPLGEGKSTTTVGLCQALGA+LDKKVVTCLRQPSQGPTFGIK       YSQVIPMDEFNLHLTGDIH               RIFHE SQSDKALFNRLCPPNKEG+RSFS+IMFRRL KLGISKT PE+LTPEEI +FARLDIDP SITW+RVMD
Sbjct:    2 SSSTRKLEVVSPVPADIDIANSVEPLHISEIAKDLNINPLHYDLYGKYKAKVLLSAFDELQGQEDGYYVVVGGITPTPLGEGKSTTTVGLCQALGAYLDKKVVTCLRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITASNNLLAAAIDTRIFHETSQSDKALFNRLCPPNKEGKRSFSDIMFRRLTKLGISKTSPEELTPEEIKKFARLDIDPASITWRRVMD 234          

BLAST of FC925003 vs. ExPASy Swiss-Prot
Match: FTHS_SPIOL (Formate--tetrahydrofolate ligase OS=Spinacia oleracea PE=1 SV=3)

HSP 1 Score: 373.244 bits (957), Expect = 8.062e-103
Identity = 182/234 (77.78%), Postives = 200/234 (85.47%), Query Frame = 2

Query:   47 SSKTVRKLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPPSITWKRVMD 748
            SSKTVRKL+V +PVPADIDIAN+VEPLHI++IA +LNL P HYDLYGKYKAKVLLSVLDE++ + DGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIK       YSQVIPMDEFNLHLTGDIH               R+FHE++QSDKALFNRLCPPNKEG+R+F NIM RRLKKLGI KT P+DLTPEE+ +FARLDIDP SITW+RVMD
Sbjct:    4 SSKTVRKLEVATPVPADIDIANAVEPLHIADIAADLNLSPRHYDLYGKYKAKVLLSVLDEVQETQDGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITASNNLLAAAIDTRMFHESTQSDKALFNRLCPPNKEGKRTFCNIMHRRLKKLGIDKTNPDDLTPEEVTKFARLDIDPDSITWRRVMD 237          

BLAST of FC925003 vs. ExPASy Swiss-Prot
Match: C1TC_HUMAN (C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens GN=MTHFD1 PE=1 SV=3)

HSP 1 Score: 264.618 bits (675), Expect = 4.038e-70
Identity = 138/227 (60.79%), Postives = 163/227 (71.81%), Query Frame = 2

Query:   68 LQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPPSITWKRVMD 748
            L + +PVP+DIDI+ S +P  I ++A+E+ L     +LYG+ KAKVLLS L+ L+   DG YVVV GITPTPLGEGKSTTT+GL QALGA L + V  C+RQPSQGPTFGIK       YSQVIPM+EFNLHLTGDIH               RIFHE +Q+DKALFNRL  P+  G R FS+I  RRLK+LGI KT P  LT EEINRFARLDIDP +ITW+RV+D
Sbjct:  310 LNLKTPVPSDIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSALERLKHRPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLV-PSVNGVRRFSDIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLD 535          

BLAST of FC925003 vs. ExPASy Swiss-Prot
Match: C1TC_RAT (C-1-tetrahydrofolate synthase, cytoplasmic OS=Rattus norvegicus GN=Mthfd1 PE=1 SV=3)

HSP 1 Score: 263.077 bits (671), Expect = 1.175e-69
Identity = 137/228 (60.09%), Postives = 162/228 (71.05%), Query Frame = 2

Query:   65 KLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPPSITWKRVMD 748
            KL + +PVP+DI I+ S +P  I  +A+E+ L     +LYG+ KAKVLLS LD L+   DG YVVV GITPTPLGEGKSTTT+GL QALGA L + V  C+RQPSQGPTFGIK       YSQVIPM+EFNLHLTGDIH               RIFHE +Q+DKALFNRL  P+  G R FS+I  RRL++LGI KT P  LT +EINRFARLDIDP +ITW+RV+D
Sbjct:  309 KLNLKTPVPSDIAISRSCKPKLIGNLAREIGLLTEEVELYGETKAKVLLSALDRLKHQPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLHQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLV-PSVNGVRKFSDIQIRRLRRLGIEKTDPAALTDDEINRFARLDIDPETITWQRVLD 535          

BLAST of FC925003 vs. ExPASy Swiss-Prot
Match: C1TC_PONAB (C-1-tetrahydrofolate synthase, cytoplasmic OS=Pongo abelii GN=MTHFD1 PE=2 SV=3)

HSP 1 Score: 262.692 bits (670), Expect = 1.535e-69
Identity = 138/227 (60.79%), Postives = 162/227 (71.37%), Query Frame = 2

Query:   68 LQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPPSITWKRVMD 748
            L + +P P+DIDI+ S +P  I ++A+E+ L     +LYG+ KAKVLLS L+ L+   DG YVVV GITPTPLGEGKSTTTVGL QALGA L + V  C+RQPSQGPTFGIK       YSQVIPM+EFNLHLTGDIH               RIFHE +Q+DKALFNRL  P+  G R FS+I  RRLK+LGI KT P  LT EEINRFARLDIDP +ITW+RV+D
Sbjct:  310 LNLKTPDPSDIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSALERLKHRPDGKYVVVTGITPTPLGEGKSTTTVGLVQALGAHLYQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAFTAANNLVAAAIDARIFHELTQTDKALFNRLV-PSVNGVRKFSDIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLD 535          

BLAST of FC925003 vs. ExPASy Swiss-Prot
Match: C1TC_MOUSE (C-1-tetrahydrofolate synthase, cytoplasmic OS=Mus musculus GN=Mthfd1 PE=1 SV=3)

HSP 1 Score: 262.307 bits (669), Expect = 2.004e-69
Identity = 137/228 (60.09%), Postives = 162/228 (71.05%), Query Frame = 2

Query:   65 KLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPPSITWKRVMD 748
            KL + +PVP+DI I+ S +P  I  +A+E+ L     +LYG+ KAKVLLS LD L+   DG YVVV GITPTPLGEGKSTTT+GL QALGA L + V  C+RQPSQGPTFGIK       YSQVIPM+EFNLHLTGDIH               RIFHE +Q+DKALFNRL  P+  G R FS+I  RRL++LGI KT P  LT +EINRFARLDIDP +ITW+RV+D
Sbjct:  309 KLNLKTPVPSDIAISRSCKPKLIGNLAREIGLLTEEVELYGETKAKVLLSALDRLKYQPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLRQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLV-PSVNGIRKFSDIQIRRLRRLGIEKTDPTTLTDDEINRFARLDIDPETITWQRVLD 535          

BLAST of FC925003 vs. ExPASy Swiss-Prot
Match: C1TM_HUMAN (Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens GN=MTHFD1L PE=1 SV=1)

HSP 1 Score: 249.98 bits (637), Expect = 1.029e-65
Identity = 129/228 (56.58%), Postives = 158/228 (69.30%), Query Frame = 2

Query:   65 KLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPPSITWKRVMD 748
            KLQ +SPVP+DI+I+    P  +  +A+E+ L  +  ++YGK KAKV LSVL+ L+  ADG YV+V GITPTPLGEGKST T+GL QAL A L+     CLRQPSQGPTFG+K       Y+QVIPM+EFNLHLTGDIH               RI HE +Q+DKAL+NRL  P   G R FS I   RLKKLGI+KT P  LT EE+++FARLDIDP +ITW+RV+D
Sbjct:  352 KLQPLSPVPSDIEISRGQTPKAVDVLAKEIGLLADEIEIYGKSKAKVRLSVLERLKDQADGKYVLVAGITPTPLGEGKSTVTIGLVQALTAHLNVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAITAANNLLAAAIDTRILHENTQTDKALYNRLV-PLVNGVREFSEIQLARLKKLGINKTDPSTLTEEEVSKFARLDIDPSTITWQRVLD 578          

BLAST of FC925003 vs. ExPASy Swiss-Prot
Match: C1TM_BOVIN (Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Bos taurus GN=MTHFD1L PE=2 SV=2)

HSP 1 Score: 247.284 bits (630), Expect = 6.672e-65
Identity = 127/228 (55.70%), Postives = 159/228 (69.74%), Query Frame = 2

Query:   65 KLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPPSITWKRVMD 748
            KLQ +SPVP+DI+I+ +  P  +  +A+E+ L  +  ++YGK KAKV LS+L+ L+  ADG YV+V GITPTPLGEGKST T+GL QAL A L+     CLRQPSQGPTFG+K       Y+QVIPM+EFNLHLTGDIH               RI HE +Q+DKAL+NRL  P+  G R FS I   RLK+LGI+KT P  LT EE+ +FARLDIDP +ITW+RV+D
Sbjct:  349 KLQPLSPVPSDIEISRAQTPKAVEILAKEIGLLADEIEIYGKSKAKVRLSLLERLKDQADGKYVLVAGITPTPLGEGKSTVTIGLVQALTAHLNVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAITAANNLLAAAIDARILHENTQTDKALYNRLV-PSVNGVREFSKIQLARLKRLGINKTDPSALTEEEMRKFARLDIDPSTITWQRVVD 575          

BLAST of FC925003 vs. ExPASy Swiss-Prot
Match: C1TM_MOUSE (Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Mus musculus GN=Mthfd1l PE=1 SV=2)

HSP 1 Score: 244.588 bits (623), Expect = 4.325e-64
Identity = 126/228 (55.26%), Postives = 155/228 (67.98%), Query Frame = 2

Query:   65 KLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPPSITWKRVMD 748
            KLQ +SPVP+DI+I+    P  +  +A+E+ L  +  ++YGK KAKV LS+L+ L+   DG YV+V GITPTPLGEGKST T+GL QAL A L      CLRQPSQGPTFG+K       Y+QVIPM+EFNLHLTGDIH               RI HE++Q+DKAL+NRL  P   G R FS I   RLKKLGI KT P  LT EE+ +FARL+IDP +ITW+RV+D
Sbjct:  351 KLQPLSPVPSDIEISRGQTPKAVDVLAKEIGLLADEIEIYGKSKAKVQLSLLERLKDQTDGKYVLVAGITPTPLGEGKSTVTIGLVQALTAHLKVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAITAANNLLAAAIDTRILHESTQTDKALYNRLV-PLVNGVREFSEIQLSRLKKLGIHKTDPSTLTEEEVRKFARLNIDPATITWQRVLD 577          

BLAST of FC925003 vs. ExPASy Swiss-Prot
Match: C1TC_YEAST (C-1-tetrahydrofolate synthase, cytoplasmic OS=Saccharomyces cerevisiae GN=ADE3 PE=1 SV=1)

HSP 1 Score: 239.965 bits (611), Expect = 1.065e-62
Identity = 126/250 (50.40%), Postives = 166/250 (66.40%), Query Frame = 2

Query:   11 N*FIKKKK*LMASSKTVR----KLQVVSPVPADIDIANSVEPLHISEIAQELNLKPNHYDLYGKYKAKVLLSVLDELEGSADGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFLDKKVVTCLRQPSQGPTFGIKXXXXXXXYSQVIPMDEFNLHLTGDIHXXXXXXXXXXXXXXXRIFHEASQSDKALFNRLCPPNKEGERSFSNIMFRRLKKLGISKTKPEDLTPEEINRFARLDIDPPSITWKRVMD 748
            N  I  K+ +  SSK ++     L++++PVP+DIDI+ + +P  I+++AQEL +  +  +LYG YKAK+   V++ L+   +G Y++V GITPTPLGEGKSTTT+GL QAL A L K  +  +RQPS GPT G+K       YSQVIPMDEFNLHLTGDIH               R+FHE +Q + A F     P K G+R F+  M RRL +LGI KT P+DLTPEEIN+FARL+IDP +IT KRV+D
Sbjct:  291 NTLIAAKRQMEESSKPLQIPPLPLKLLTPVPSDIDISRAQQPKLINQLAQELGIYSHELELYGHYKAKISPKVIERLQTRQNGKYILVSGITPTPLGEGKSTTTMGLVQALTAHLGKPAIANVRQPSLGPTLGVKGGAAGGGYSQVIPMDEFNLHLTGDIHAIGAANNLLAAAIDTRMFHETTQKNDATFYNRLVPRKNGKRKFTPSMQRRLNRLGIQKTNPDDLTPEEINKFARLNIDPDTITIKRVVD 540