EY736465

BLAST of EY736465 vs. ExPASy Swiss-Prot
Match: SEN1_YEAST (Helicase SEN1 OS=Saccharomyces cerevisiae GN=SEN1 PE=1 SV=2)

HSP 1 Score: 184.882 bits (468), Expect = 4.988e-46
Identity = 94/234 (40.17%), Postives = 142/234 (60.68%), Query Frame = 3

Query:   12 PATVISPVAEHLGYGTSLFKRLQRAGYPVKMLKTQYRMHPEVRSFPSREFYDEALEDGSDVEDYTTRDWHEYRCFGPFSFFDIHEGKESQPAGSGSWINIDEVDFVLLLFHKLISMYP-QLKSSSQLAIISPYRHQVKQFQERFKETFGVESQKVVDITTVDGCQGREKDVAIFSCVRASD-KKSIGFLADYRRMNVGITRAKSSILVVGCASTLREDKHWNNLV*SAEKQDCL 707
            P TV+S  A +  Y  SLF R+++   P  +L  QYRMHP +  FPS EFY   L+DG  ++    R WH+     P+ FFDI  G++ Q A + S+ N++E+   + L   L   +  ++  + ++ IISPYR Q+++ ++ F   FG    K +D  T+DG QG+EK++ + SCVRA D K S+GFL D+RRMNV +TRAK+SI V+G   +L + K W +L+  A+ + CL
Sbjct: 1621 PPTVLSGAASNFKYNQSLFVRMEKNSSPY-LLDVQYRMHPSISKFPSSEFYQGRLKDGPGMDILNKRPWHQLEPLAPYKFFDIISGRQEQNAKTMSYTNMEEIRVAIELVDYLFRKFDNKIDFTGKIGIISPYREQMQKMRKEFARYFGGMINKSIDFNTIDGFQGQEKEIILISCVRADDTKSSVGFLKDFRRMNVALTRAKTSIWVLGHQRSLAKSKLWRDLIEDAKDRSCL 1853          

BLAST of EY736465 vs. ExPASy Swiss-Prot
Match: SEN1_SCHPO (Helicase sen1 OS=Schizosaccharomyces pombe GN=sen1 PE=1 SV=1)

HSP 1 Score: 184.111 bits (466), Expect = 8.509e-46
Identity = 90/224 (40.18%), Postives = 143/224 (63.84%), Query Frame = 3

Query:   12 PATVISPVAEHLGYGTSLFKRLQRA-GYPVKMLKTQYRMHPEVRSFPSREFYDEALEDGSDVEDYTTRDWHEYRCFGPFSFFDIHEGKESQPAGSGSWINIDEVDFVLLLFHKLISMYPQLKSSSQLAIISPYRHQVKQFQERFKETFGVESQKVVDITTVDGCQGREKDVAIFSCVRASDKKSIGFLADYRRMNVGITRAKSSILVVGCASTLREDKHWNNLV 680
            P TV+S  A  L Y  SLF R+Q+     + +L  QYRMHP++  FPS++FYD  LEDG ++ + T + WH    F  +  FD+  GKE + + + S  N++EV++++ +  +L++ +P +  + ++ +I+PYR Q+ + +  FK  +G      +DI TVDG QG+EKD+  FSCV++  K  IGFL D+RR+NV +TRA+SS+L++G   TL+ D  W +LV
Sbjct: 1409 PPTVLSKKAASLNYSQSLFVRIQKNFSNQMCLLSIQYRMHPDISHFPSKKFYDSRLEDGDNMAEKTQQVWHVNPKFTQYRLFDVR-GKE-RTSNTMSTYNLEEVEYLVNMVDELLNKFPDVNFTGRIGVITPYRSQLHELRRAFKVKYGKSFMSTIDIQTVDGFQGQEKDIIFFSCVKSYSKHGIGFLRDFRRLNVALTRARSSLLIIGNMETLKTDDLWGSLV 1630          

BLAST of EY736465 vs. ExPASy Swiss-Prot
Match: Y4399_DICDI (Probable helicase DDB_G0274399 OS=Dictyostelium discoideum GN=DDB_G0274399 PE=3 SV=1)

HSP 1 Score: 177.948 bits (450), Expect = 6.098e-44
Identity = 103/239 (43.10%), Postives = 138/239 (57.74%), Query Frame = 3

Query:   12 PATVISPVAEHLGYGTSLFKRLQRAGYPVKMLKTQYRMHPEVRSFPSREFYDEALEDGSDVEDYTTRDWHEYRCFGPFSFFDIHEGKESQPAGSGSWINIDEVDFVLLLFHKLISMYPQLKSSSQLAIISPYRHQVKQFQERFKETFGVESQKVVDITTVDGCQGREKDVAIFSCVRA--SDKKSIGFLADYRRMNVGITRAKSSILVVGCASTLREDKHWNNLV*SAEKQDCLFRLSK 722
            PAT+ISP+A    Y  SLF+RLQ    P  ML TQYRMH  +R+FPSR FY + L DG ++    T  +H    FGP  F+D+    E++P G GS  N  E    + LF     +YP    +S++ IISPYR QV   +E FK   G+       I TVDG QGRE+++ IFSCVRA   +   IGFL+D RRMNV +TR +SS+L++G    L  +K WN L+   +    L  ++K
Sbjct:  622 PATIISPLAIKYKYDQSLFQRLQEKNSP-HMLTTQYRMHSLIRAFPSRHFYQDLLLDGPNIPSRATH-YHSNPFFGPLVFYDLSWSTETKPGG-GSVFNEHECKMAMYLFQLFTKVYPDEDFASRIGIISPYRQQVLALREIFKNYPGIS------IDTVDGFQGREREIIIFSCVRAPVEEGAGIGFLSDVRRMNVALTRPRSSLLILGNTKALSINKDWNELIQHTQNNQQLIPVTK 851          

BLAST of EY736465 vs. ExPASy Swiss-Prot
Match: YGSA_SCHPO (Uncharacterized ATP-dependent helicase C29A10.10c OS=Schizosaccharomyces pombe GN=SPBC29A10.10c PE=2 SV=1)

HSP 1 Score: 175.637 bits (444), Expect = 3.026e-43
Identity = 93/228 (40.79%), Postives = 143/228 (62.72%), Query Frame = 3

Query:   12 PATVISPVAEHLGYGTSLFKRL-QRAGYPVKMLKTQYRMHPEVRSFPSREFYDEALEDGSDVEDYTTRDWHEYRCFGPFSFFDIHEGKESQPAGSGSWINIDEVDFVLLLFHKLISMYPQLKSSSQLAIISPYRHQVKQFQERFKETFGVESQKVVDITTVDGCQGREKDVAIFSCVRASDKKSIGFLADYRRMNVGITRAKSSILVVGCASTLREDKHWNNLV*SAE 692
            P TV+S  +   GY  SL+ R+ ++      +L  QYRM+PE+  FPS+ FY+  L DG ++   T+R WHE    G + FF++H G E+  + S S  N++E  F+LLL+ +LI  Y  +    ++ +++PYR QV+Q + +F+  +G    K +DI TVDG QG+EKD+ IFSCVR+S    IGFL D RR+NV +TRAKSS+ +VG +  L ++  + +L+  A+
Sbjct: 1547 PPTVLSKTSAKFGYSQSLYVRMFKQHNESACLLSIQYRMNPEISRFPSKFFYNSKLLDGPNMSAVTSRPWHEDPQLGIYRFFNVH-GTEAF-SNSKSLYNVEEASFILLLYERLIQCYLNIDFEGKIGVVTPYRSQVQQLRSQFQRKYGSIIFKHLDIHTVDGFQGQEKDIIIFSCVRSSMSGGIGFLQDLRRLNVALTRAKSSLYIVGNSKPLMQEDIFYSLIEDAK 1772          

BLAST of EY736465 vs. ExPASy Swiss-Prot
Match: SETX_HUMAN (Probable helicase senataxin OS=Homo sapiens GN=SETX PE=1 SV=3)

HSP 1 Score: 132.494 bits (332), Expect = 2.938e-30
Identity = 88/247 (35.63%), Postives = 130/247 (52.63%), Query Frame = 3

Query:   12 PATVISPVAEHLGYGTSLFKRLQR-----------AGYPVKMLKTQYRMHPEVRSFPSREFYDEALEDGSDVEDYT-TRDWHEYRCFGPFSFFDIHEGKESQPAGSGSWINIDEVDFVLLLFHKLISMYPQLKSSSQLAIISPYRHQVKQFQERFKETFGVESQKVVDITTVDGCQGREKDVAIFSCVRASD-KKSIGFLADYRRMNVGITRAKSSILVVGCASTLREDKHWNNLV*SAEKQDCLFR 713
            P TVIS  A+  GY  S+  R  R           +  P+  L  QYRMHP++  FPS   Y+  L+     E    + DW     F P+  FD+ +G E +   + S+IN+ E+  V+ +  KLI    +  S   + II+ Y+ Q    Q+   + F  +    VD  TVD  QGR+KD  I +CVRA+  + SIGFLA  +R+NV ITRAK S+ ++G   TL E++HWN L+  A+K+  + +
Sbjct: 2212 PPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSDWP----FQPYLVFDVGDGSERRD--NDSYINVQEIKLVMEII-KLIKDKRKDVSFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVD--TVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIK 2449          

BLAST of EY736465 vs. ExPASy Swiss-Prot
Match: SETX_MOUSE (Probable helicase senataxin OS=Mus musculus GN=Setx PE=2 SV=1)

HSP 1 Score: 130.954 bits (328), Expect = 8.548e-30
Identity = 91/255 (35.69%), Postives = 132/255 (51.76%), Query Frame = 3

Query:   12 PATVISPVAEHLGYGTSLFKRLQR-----------AGYPVKMLKTQYRMHPEVRSFPSREFYDEALEDGSDVEDYTTRDWHEYRC-----FGPFSFFDIHEGKESQPAGSGSWINIDEVDFVLLLFHKLISMYPQLKSSSQLAIISPYRHQVKQFQERFKETFGVESQKVVDITTVDGCQGREKDVAIFSCVRASDKK-SIGFLADYRRMNVGITRAKSSILVVGCASTLREDKHWNNLV*SAEKQDCLFRLSKP 725
            P TVIS  A+  GY  S+  R  +              PV  L  QYRMHP++  FPS   Y++ L+        T R     RC     F P+  FD+ +G E +   + S+IN+ E+  V+ +  KLI    +  S   + II+ Y+ Q    Q+  ++ F  +    VD  TVD  QGR+KD  I +CVRAS  + SIGFLA  +R+NV ITRAK S+ ++G   TL E++HW  L+  A+K+  + + S P
Sbjct: 2188 PPTVISMKAQEYGYDQSMMARFCKLLEENVEQNMIGRLPVLQLTIQYRMHPDICLFPSNYVYNKNLK--------TNRLTESIRCSSEWPFQPYLVFDVGDGSERRD--NDSYINVQEIKLVMEII-KLIKEKRKDISFRNIGIITHYKAQKTMIQKDLEKEFDKKGPAEVD--TVDAFQGRQKDCIIVTCVRASAVQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWYELIQDAQKRGAIIKTSDP 2429          

BLAST of EY736465 vs. ExPASy Swiss-Prot
Match: RENT1_CAEEL (Regulator of nonsense transcripts 1 OS=Caenorhabditis elegans GN=smg-2 PE=1 SV=1)

HSP 1 Score: 125.561 bits (314), Expect = 3.591e-28
Identity = 89/235 (37.87%), Postives = 122/235 (51.91%), Query Frame = 3

Query:   21 VISPVAEHLGYGTSLFKRLQRAGYPVKMLKTQYRMHPEVRSFPSREFYDEALEDGSDVED--YTTRDWHEYRCFGPFSFFDIHEGKESQPAGSGSWINIDEVDFVLLLFHKLISMYPQLKSSSQLAIISPYRHQVKQFQERFKETFGVESQKV---VDITTVDGCQGREKDVAIFSCVRASDKKSIGFLADYRRMNVGITRAKSSILVVGCASTLREDKHWNNLV*SAEKQDCLF 710
            VI   A   G   SLF+RL   G     L+ QYRMHP +  FPS  FYD +L++G    D   T  DWH  +   P +FF    G E   A   S++N  E   V  L  KLI    Q     Q+ +I+ Y  Q + F   +  T G  + K+   V+I +VD  QGREKD  I +CVR++D   IGFL+D RR+NV ITRAK  +++VG A  L     W+ L+   + ++ L+
Sbjct:  644 VICKKAAIAGLSQSLFERLVLLGIRPFRLQVQYRMHPVLSEFPSNVFYDGSLQNGVTENDRHMTGVDWHWPKPNKP-AFFWHCSGSEELSASGTSFLNRTEAANVEKLVSKLIKAGVQ---PHQIGVITSYEGQ-RSFIVNYMHTQGTLNSKLYENVEIASVDAFQGREKDYIIVTCVRSNDILGIGFLSDPRRLNVAITRAKYGLVLVGNAKVLARHDLWHELINHYKSKEMLY 873          

BLAST of EY736465 vs. ExPASy Swiss-Prot
Match: RENT1_ARATH (Regulator of nonsense transcripts 1 homolog OS=Arabidopsis thaliana GN=UPF1 PE=1 SV=2)

HSP 1 Score: 121.324 bits (303), Expect = 6.773e-27
Identity = 80/230 (34.78%), Postives = 119/230 (51.74%), Query Frame = 3

Query:   36 AEHLGYGTSLFKRLQRAGYPVKMLKTQYRMHPEVRSFPSREFYDEALEDG-SDVEDYTTRDWHEYRCFGPFSFFDIHEGKESQPAGSGSWINIDEVDFVLLLFHKLISMYPQLKSS---SQLAIISPYRHQVKQFQERFKETFGVESQ--KVVDITTVDGCQGREKDVAIFSCVRASDKKSIGFLADYRRMNVGITRAKSSILVVGCASTLREDKHWNNLV*SAEKQDCL 707
            A   G   SLF+RL   G     L+ QYRMHP +  FPS  FY+  L++G + +E  TT     +       FF +  G+E   A   S++N  E   V     KL++ +  LKS    SQ+ +I+PY  Q             +  Q  K +++ +VD  QGREKD  I SCVR+++ + IGFL D RR+NV +TRA+  I+++G    L +   WN L+   ++ +CL
Sbjct:  695 AARAGLAQSLFERLVTLGIKPIRLQVQYRMHPALSEFPSNSFYEGTLQNGVTIIERQTTGIDFPWPVPNRPMFFYVQLGQEEISASGTSYLNRTEAANV----EKLVTAF--LKSGVVPSQIGVITPYEGQRAYIVNYMARNGSLRQQLYKEIEVASVDSFQGREKDYIILSCVRSNEHQGIGFLNDPRRLNVALTRARYGIVILGNPKVLSKQPLWNGLLTHYKEHECL 918          

BLAST of EY736465 vs. ExPASy Swiss-Prot
Match: RENT1_TAKRU (Putative regulator of nonsense transcripts 1 OS=Takifugu rubripes GN=rent1 PE=3 SV=1)

HSP 1 Score: 120.168 bits (300), Expect = 1.509e-26
Identity = 80/233 (34.33%), Postives = 127/233 (54.51%), Query Frame = 3

Query:   21 VISPVAEHLGYGTSLFKRLQRAGYPVKMLKTQYRMHPEVRSFPSREFYDEALEDGSDVEDYTTRDWHEYRCFGPFS--FFDIHEGKESQPAGSGSWINIDEVDFVLLLFHKLISMYPQLKSSSQLAIISPYRHQVKQFQERFKETFGVESQKV--VDITTVDGCQGREKDVAIFSCVRASDKKSIGFLADYRRMNVGITRAKSSILVVGCASTLREDKHWNNLV*SAEKQDCL 707
            V+   A   G   SLF+RL   G     L+ QYRMHP + +FPS  FY+ +L++G    D   + + +++   P    FF + +G+E   +   S++N  E   V  +  +L+    +     Q+ II+PY  Q + +  ++ +  G    K+  V+I +VD  QGREKD  I SCVRA++ + IGFL D RR+NV +TRAK  +++VG    L +   WNNL+ + ++Q  L
Sbjct:  651 VMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAGDRIKKGF-DFQWPQPEKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTRLLKAGAK---PDQIGIITPYEGQ-RSYLVQYMQFSGSLHTKLYQVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRAKYGVIIVGNPKALSKQPLWNNLLNNYKEQKVL 878          

BLAST of EY736465 vs. ExPASy Swiss-Prot
Match: RENT1_DICDI (Regulator of nonsense transcripts 1 OS=Dictyostelium discoideum GN=upf1 PE=3 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 2.574e-26
Identity = 74/217 (34.10%), Postives = 118/217 (54.38%), Query Frame = 3

Query:   48 GYGTSLFKRLQRAGYPVKMLKTQYRMHPEVRSFPSREFYDEALEDG---SDVEDYTTRDWHEYRCFGPFSFFDIHEGKESQPAGSGSWINIDEVDFVLLLFHKLISMYPQLKS-SSQLAIISPYRHQVKQFQERFKET--FGVESQKVVDITTVDGCQGREKDVAIFSCVRASDKKSIGFLADYRRMNVGITRAKSSILVVGCASTLREDKHWNNLV 680
            G   SLF+RL   G+  + L  QYRMHP +  FPS   Y+  L      +D +  +   W + +   P  FF+    +E   +G+ S+IN  E      +  K+++ + +L S   Q+ II+PY  Q        +++    +E  K +++ +VD  QGREKD  I SCVR++D + IGFL D RR+NV +TRA+  ++++G A  L +D  WN+L+
Sbjct:  749 GLSQSLFERLISLGHHPERLTIQYRMHPSLTEFPSNTSYEGQLVSELSHTDRDSQSKFPWPQPK--DPMFFFNCTGSEEISSSGT-SFINTTEAS----ICEKIVTKFLELGSLPGQIGIITPYEGQRAYITSHMQKSGKLNLELYKSIEVASVDSFQGREKDYIILSCVRSNDYQGIGFLQDPRRLNVALTRARFGLIILGNAKVLSKDPLWNSLI 958