EY754093

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: ALDR_HORVU (Aldose reductase OS=Hordeum vulgare PE=1 SV=1)

HSP 1 Score: 139.043 bits (349), Expect = 6.848e-47
Identity = 73/179 (40.78%), Postives = 101/179 (56.42%), Query Frame = 3

Query:  333 MHWPVRTKKGFISLNPE--DLLQPDIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSDVLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPEDLFAKFSGIEQAK 863
            +HWP R K G   + PE  ++L+ D+   WK ME L   G  + IGV N++V KL  LL+ A++ PAV Q+E HPGW+ +K+ E C   GIHV              + ++   PV++ VA KL KTPGQV I+W LQ G SV+PK   +   + +  VFGW IPE+ F     I+  K
Sbjct:  120 IHWPFRLKDG-AHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQMEMHPGWKNDKIFEACKKHGIHVTAYSPLGSS-----EKNLAHDPVVEKVANKLNKTPGQVLIKWALQRGTSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDEK 292          

HSP 2 Score: 70.4774 bits (171), Expect = 6.848e-47
Identity = 36/85 (42.35%), Postives = 48/85 (56.47%), Query Frame = 1

Query:  103 YFELNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL*CTGQCERR 357
            +F L +G  MP++GLGTW+A               GYRH+D A  YG EKE+G  LK   E G + R+DL++TSK+ CT     R
Sbjct:   15 HFVLKSGHAMPAVGLGTWRAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEAG-IDRKDLFVTSKIWCTNLAPER 98          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1A1_CHICK (Alcohol dehydrogenase [NADP+] OS=Gallus gallus GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 2.952e-41
Identity = 67/181 (37.02%), Postives = 98/181 (54.14%), Query Frame = 3

Query:  312 MDHLQA-LMHWPVRTKKG--FISLNPEDLLQ---PDIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPED 827
            +D+L   LMHWP   ++G      NP+  ++    D  +TWKAME L + G A+AIG+SNF+ +++ D+L VA V PAV QVECHP   Q +L   C  +G+ V            W   D   +L+ P IK +AEK  K+P Q+ +RW  Q     +PK    A   ++  VF +S+ E+
Sbjct:  106 LDYLDLYLMHWPHAFERGDNLFPKNPDGTMRYDYTDYKDTWKAMEKLVEKGLAKAIGLSNFNSRQIDDVLSVATVKPAVLQVECHPYLAQNELIAHCQKRGLVVTAYSPLGSPDRMWKHPDEPVLLEEPGIKKLAEKYKKSPAQILLRWQAQRKVVTIPKSVTPARILQNLQVFDFSLTEE 286          

HSP 2 Score: 75.485 bits (184), Expect = 2.952e-41
Identity = 37/77 (48.05%), Postives = 50/77 (64.94%), Query Frame = 1

Query:  103 YFELNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKK-LFEDGVVKREDLWITSKL 330
            +  L NG K+P IGLGTW+++PG V          GYRH+DCA  Y NE EIG   ++ +  + V+KREDL++TSKL
Sbjct:    7 FVALYNGQKIPLIGLGTWKSEPGQVKEAVKYALSVGYRHVDCAAAYSNEAEIGDAFQECVGPNKVIKREDLFVTSKL 83          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1A1_XENLA (Alcohol dehydrogenase [NADP+] OS=Xenopus laevis GN=akr1a1 PE=2 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 1.445e-40
Identity = 64/181 (35.36%), Postives = 98/181 (54.14%), Query Frame = 3

Query:  312 MDHLQA-LMHWPVRTKKG--FISLNPEDLLQPDIPN---TWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPED 827
            +D+L   LMHWP   K+G      NP+  +Q D+ +   TWKAME L + G A+AIG+SNF+ +++ D+L +A V PAV QVECHP   Q +L   C S G+ +            W K +   +L+ P I  +A+K   +  Q+ +RW +Q     +PK    A   ++  VF +S+ E+
Sbjct:  106 LDYLDLYLMHWPYAFKRGDQVFPQNPDGSVQYDLTDYKDTWKAMEKLVEKGLAKAIGLSNFNKRQMDDILSIATVKPAVLQVECHPYLAQNELIACCRSHGLVLTGYSPLGSPDRSWRKPEDPVLLEEPGIIAMAKKYNISEAQILLRWQVQRRVVTIPKSVTPARILQNLQVFDFSLSEE 286          

HSP 2 Score: 79.7221 bits (195), Expect = 1.445e-40
Identity = 39/80 (48.75%), Postives = 53/80 (66.25%), Query Frame = 1

Query:   94 NVQYFELNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKK-LFEDGVVKREDLWITSKL 330
            +V+Y  L  G KMP IGLGTW++ PG V          GYRHIDCA+ YGNE E+G  +K+ +  D  +KRE++++TSKL
Sbjct:    4 SVEYETLYTGQKMPLIGLGTWKSAPGQVKDAVKYALGVGYRHIDCAFVYGNETEVGEAIKESVGPDKGLKREEVFVTSKL 83          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1A1_XENTR (Alcohol dehydrogenase [NADP+] OS=Xenopus tropicalis GN=akr1a1 PE=2 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 2.452e-40
Identity = 63/181 (34.81%), Postives = 99/181 (54.70%), Query Frame = 3

Query:  312 MDHLQA-LMHWPVRTKKG--FISLNPEDLLQPDIPN---TWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPED 827
            +D+L   LMHWP   K+G      NP+  +Q D+ +   TWKAME L   G  +AIG+SNF+ +++ D++ +A V PAV QVECHP   Q +L  +C++ G+              W K +   +L+ P I  +A+K GK+  Q+ +RW +Q     +PK        ++F VF +S+ E+
Sbjct:  106 LDYLDLYLMHWPYAFKRGDQIFPQNPDGSVQYDLTDYKDTWKAMEKLVKQGLTKAIGLSNFNKRQIDDIISIATVKPAVLQVECHPYLAQNELIAYCHAHGLVFTGYSPLGSPDRSWRKPEDPVLLEEPGIIAMAKKYGKSEAQILLRWQVQRKVVSIPKSVTPTRILQNFQVFDFSLSEE 286          

HSP 2 Score: 76.2554 bits (186), Expect = 2.452e-40
Identity = 37/79 (46.84%), Postives = 51/79 (64.56%), Query Frame = 1

Query:   97 VQYFELNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKK-LFEDGVVKREDLWITSKL 330
            V+Y  L  G K+P IGLGTW++ PG V          GYRHIDCA+ YGNE E+G  +K+ +  D  + RE++++TSKL
Sbjct:    5 VEYETLYTGQKIPLIGLGTWKSAPGQVKDAVKYALGVGYRHIDCAFVYGNETEVGEAIKESVGSDKGLSREEVFVTSKL 83          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AKCL2_PIG (1,5-anhydro-D-fructose reductase OS=Sus scrofa GN=AKR1E2 PE=1 SV=2)

HSP 1 Score: 103.219 bits (256), Expect = 3.199e-40
Identity = 65/184 (35.33%), Postives = 94/184 (51.09%), Query Frame = 3

Query:  330 LMHWPVRTKKGFISLNPED------LLQPDIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVA--RVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSDVLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPEDLFAKFSGIEQ 857
            L+HWP+  K G + L P D          D  +TW+AME L   G  RAIGVSNF+ ++L+ LL     RV P  NQ+ECHP   Q+KL  FC S+ + V                 +L+ PVI+ +A+K GK+  Q+ IR+ +Q    V+PK  N      +F VF + + E       G+++
Sbjct:  100 LIHWPMGFKPGEVDL-PVDRSGMIVASNTDFLDTWEAMEDLVIEGLVRAIGVSNFNHEQLERLLNKPNLRVKPVTNQIECHPYLTQKKLISFCQSRNVSVTAYRPLGGSSEG---VPLLEDPVIQTIAQKHGKSAAQILIRFQIQRNVIVIPKSVNPKRILENFQVFDFELSEQDMTDLLGLDR 279          

HSP 2 Score: 83.9593 bits (206), Expect = 3.199e-40
Identity = 38/71 (53.52%), Postives = 47/71 (66.20%), Query Frame = 1

Query:  127 KMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL*CT 339
            K+P +GLGTWQA PG V          GYRH DCAY Y NE E+G  ++   ++GVV+REDL+I SKL CT
Sbjct:    3 KIPVLGLGTWQAAPGEVTEAVKVAIDTGYRHFDCAYLYHNENEVGVGIQAKIDEGVVRREDLFIVSKLWCT 73          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1A1_MOUSE (Alcohol dehydrogenase [NADP+] OS=Mus musculus GN=Akr1a1 PE=1 SV=3)

HSP 1 Score: 106.686 bits (265), Expect = 1.200e-39
Identity = 60/176 (34.09%), Postives = 97/176 (55.11%), Query Frame = 3

Query:  330 LMHWPVRTKKGF--ISLNPEDLLQPDIPN---TWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSI-PEDL 830
            LMHWP   ++G      N +  ++ D  +   TWKA+E L   G  +A+G+SNF+ +++ D+L VA V PAV QVECHP   Q +L   C+++G+ V            W   D   +L+ PV+  +AEK G++P Q+ +RW +Q     +PK  N +   ++  VF ++  PE++
Sbjct:  111 LMHWPYAFERGDNPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEM 286          

HSP 2 Score: 78.5666 bits (192), Expect = 1.200e-39
Identity = 40/74 (54.05%), Postives = 48/74 (64.86%), Query Frame = 1

Query:  112 LNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDG-VVKREDLWITSKL 330
            L+ G KMP IGLGTW+++PG V          GYRHIDCA  YGNE EIG  LK+    G  V RE+L++TSKL
Sbjct:    8 LHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSGKAVPREELFVTSKL 81          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1A1_RAT (Alcohol dehydrogenase [NADP+] OS=Rattus norvegicus GN=Akr1a1 PE=1 SV=2)

HSP 1 Score: 106.686 bits (265), Expect = 2.037e-39
Identity = 61/176 (34.66%), Postives = 96/176 (54.55%), Query Frame = 3

Query:  330 LMHWPVRTKKGF--ISLNPEDLLQPDIPN---TWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSI-PEDL 830
            LMHWP   ++G      N +  ++ D  +   TWKA+EAL   G  +A+G+SNFS +++ D+L VA V PAV QVECHP   Q +L   C ++G+ V            W   D   +L+ PV+  +AEK G++P Q+ +RW +Q     +PK    +   ++  VF ++  PE++
Sbjct:  111 LMHWPYAFERGDNPFPKNADGTVKYDSTHYKETWKALEALVAKGLVKALGLSNFSSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSITPSRILQNIQVFDFTFSPEEM 286          

HSP 2 Score: 77.7962 bits (190), Expect = 2.037e-39
Identity = 40/74 (54.05%), Postives = 48/74 (64.86%), Query Frame = 1

Query:  112 LNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDG-VVKREDLWITSKL 330
            L+ G KMP IGLGTW+++PG V          GYRHIDCA  YGNE EIG  LK+    G  V RE+L++TSKL
Sbjct:    8 LHTGQKMPLIGLGTWKSEPGQVKAAIKYALSVGYRHIDCASVYGNETEIGEALKESVGAGKAVPREELFVTSKL 81          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1A1_BOVIN (Alcohol dehydrogenase [NADP+] OS=Bos taurus GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 4.504e-39
Identity = 60/176 (34.09%), Postives = 95/176 (53.98%), Query Frame = 3

Query:  330 LMHWPVRTKKGFISL--NPEDLLQPDIPN---TWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSI-PEDL 830
            LMHWP   ++G      N +  ++ D  +   TW+A+EAL   G  RA+G+SNF+ +++ D+L VA V PAV QVECHP   Q +L   C ++ + V            W   +   +LK PV+  +AEK G++P Q+ +RW +Q   S +PK    +    +  VF ++  PE++
Sbjct:  111 LMHWPYAFERGDSPFPKNADGTIRYDSTHYKETWRALEALVAKGLVRALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCQARNLEVTAYSPLGSSDRAWRDPEEPVLLKEPVVLALAEKHGRSPAQILLRWQVQRKVSCIPKSVTPSRILENIQVFDFTFSPEEM 286          

HSP 2 Score: 77.7962 bits (190), Expect = 4.504e-39
Identity = 40/74 (54.05%), Postives = 48/74 (64.86%), Query Frame = 1

Query:  112 LNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDG-VVKREDLWITSKL 330
            L+ G KMP IGLGTW++ PG V          GYRHIDCA  YGNE EIG  LK+    G +V RE+L++TSKL
Sbjct:    8 LHTGQKMPLIGLGTWKSDPGQVKAAIKYALSVGYRHIDCAAIYGNETEIGEALKENVGPGKLVPREELFVTSKL 81          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1A1_PIG (Alcohol dehydrogenase [NADP+] OS=Sus scrofa GN=AKR1A1 PE=1 SV=2)

HSP 1 Score: 106.686 bits (265), Expect = 5.868e-39
Identity = 60/176 (34.09%), Postives = 96/176 (54.55%), Query Frame = 3

Query:  330 LMHWPVRTKKGF--ISLNPEDLLQPDIPN---TWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSI-PEDL 830
            LMHWP   ++G      N +  ++ D  +   TWKA+EAL   G  RA+G+SNFS +++ D+L VA V PAV QVECHP   Q +L   C ++G+ V            W   +   +L+ PV++ +AEK  ++P Q+ +RW +Q     +PK    +   ++  VF ++  PE++
Sbjct:  111 LMHWPYAFERGDNPFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEKYNRSPAQILLRWQVQRKVICIPKSVTPSRIPQNIQVFDFTFSPEEM 286          

HSP 2 Score: 76.2554 bits (186), Expect = 5.868e-39
Identity = 39/74 (52.70%), Postives = 47/74 (63.51%), Query Frame = 1

Query:  112 LNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDG-VVKREDLWITSKL 330
            L+ G KMP IGLGTW+++PG V          GYRHIDCA  YGNE EIG  L +    G  V RE+L++TSKL
Sbjct:    8 LHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIYGNELEIGEALTETVGPGKAVPREELFVTSKL 81          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1A1_HUMAN (Alcohol dehydrogenase [NADP+] OS=Homo sapiens GN=AKR1A1 PE=1 SV=3)

HSP 1 Score: 104.76 bits (260), Expect = 7.645e-39
Identity = 60/176 (34.09%), Postives = 95/176 (53.98%), Query Frame = 3

Query:  330 LMHWPVRTKKGF--ISLNPEDLLQPDIPN---TWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSI-PEDL 830
            LMHWP   ++G      N +  +  D  +   TWKA+EAL   G  +A+G+SNF+ +++ D+L VA V PAV QVECHP   Q +L   C ++G+ V            W   D   +L+ PV+  +AEK G++P Q+ +RW +Q     +PK    +   ++  VF ++  PE++
Sbjct:  111 LMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEM 286          

HSP 2 Score: 77.7962 bits (190), Expect = 7.645e-39
Identity = 40/74 (54.05%), Postives = 48/74 (64.86%), Query Frame = 1

Query:  112 LNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDG-VVKREDLWITSKL 330
            L+ G KMP IGLGTW+++PG V          GYRHIDCA  YGNE EIG  LK+    G  V RE+L++TSKL
Sbjct:    8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKL 81