EY720487

BLAST of EY720487 vs. ExPASy Swiss-Prot
Match: MTHR1_MAIZE (Methylenetetrahydrofolate reductase 1 OS=Zea mays PE=2 SV=1)

HSP 1 Score: 293.123 bits (749), Expect = 5.757e-91
Identity = 135/159 (84.91%), Postives = 146/159 (91.82%), Query Frame = 2

Query:  167 MKVIDKIQEKVASDKVVFSFEFFPPKTEDGVENLFERMDRMVAHNPAFCDITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIRGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPD 643
            MKVI+KI E     +  FSFE+FPPKTE+GVENLFERMDRMVAH P+FCDITWGAGGSTADLTL+IANRMQN +CVETMMHLTCTNMPVEKIDHAL+TIKSNGIQNVLALRGDPPHGQDKFVQ+ GGFACALDLV+HIR+ YGDYFGITVAGYPE HPD
Sbjct:    1 MKVIEKILEAAGDGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDKFVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPD 159          

HSP 2 Score: 63.5438 bits (153), Expect = 5.757e-91
Identity = 36/81 (44.44%), Postives = 45/81 (55.56%), Query Frame = 1

Query:  661 GWAVMNHIKSDLLYLKKKVDAGGDLITTQRCYETGLSSKCVKNGRHMGMTCPHGRGNEAHKDA*GVLGPCGRCANKIPPEI 903
            G A +    +DL YLK+KVDAG DLI TQ  Y+T +  K V + R +G+TCP   G     +  G L   G C  KIP EI
Sbjct:  165 GGATLEAYSNDLAYLKRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPSEI 245          

BLAST of EY720487 vs. ExPASy Swiss-Prot
Match: MTHR1_ARATH (Methylenetetrahydrofolate reductase 1 OS=Arabidopsis thaliana GN=MTHFR1 PE=1 SV=1)

HSP 1 Score: 288.115 bits (736), Expect = 3.104e-89
Identity = 132/159 (83.02%), Postives = 144/159 (90.57%), Query Frame = 2

Query:  167 MKVIDKIQEKVASDKVVFSFEFFPPKTEDGVENLFERMDRMVAHNPAFCDITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIRGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPD 643
            MKV+DKI+      +  FSFEFFPPKTEDGVENLFERMDR+V++ P FCDITWGAGGSTADLTL+IA+RMQN ICVETMMHLTCTNMP+EKIDHAL+TI+SNGIQNVLALRGDPPHGQDKFVQ+ GGFACALDLV HIRS YGDYFGITVAGYPE HPD
Sbjct:    1 MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGSTADLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQDKFVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPD 159          

HSP 2 Score: 62.7734 bits (151), Expect = 3.104e-89
Identity = 36/81 (44.44%), Postives = 44/81 (54.32%), Query Frame = 1

Query:  661 GWAVMNHIKSDLLYLKKKVDAGGDLITTQRCYETGLSSKCVKNGRHMGMTCPHGRGNEAHKDA*GVLGPCGRCANKIPPEI 903
            G A     +SDL YLKKKVDAG DLI TQ  Y+T +  K V + R +G+ CP   G     +  G L   G C  KIP E+
Sbjct:  165 GLATPESYQSDLAYLKKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTKIPAEL 245          

BLAST of EY720487 vs. ExPASy Swiss-Prot
Match: MTHR_ORYSJ (Probable methylenetetrahydrofolate reductase OS=Oryza sativa subsp. japonica GN=Os03g0815200 PE=2 SV=1)

HSP 1 Score: 290.426 bits (742), Expect = 4.048e-89
Identity = 135/159 (84.91%), Postives = 146/159 (91.82%), Query Frame = 2

Query:  167 MKVIDKIQEKVASDKVVFSFEFFPPKTEDGVENLFERMDRMVAHNPAFCDITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIRGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPD 643
            MKVI+KIQE  A  + VFSFE+FPPKTE+G++NLFERMDRMVAH P FCDITWGAGGSTADLTL+IANRMQN +CVETMMHLTCTNMPVEKID AL TIKSNGIQNVLALRGDPPHGQDKFVQ+ GGFACALDLV+HIR+ YGDYFGITVAGYPE HPD
Sbjct:    1 MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTADLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDKFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPD 159          

HSP 2 Score: 60.077 bits (144), Expect = 4.048e-89
Identity = 34/72 (47.22%), Postives = 42/72 (58.33%), Query Frame = 1

Query:  688 SDLLYLKKKVDAGGDLITTQRCYETGLSSKCVKNGRHMGMTCPHGRGNEAHKDA*GVLGPCGRCANKIPPEI 903
            +DL YLK+KVDAG DLI TQ  Y+T +  K V + R +G+TCP   G     +  G L   G C  KIP EI
Sbjct:  174 NDLAYLKQKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEI 245          

BLAST of EY720487 vs. ExPASy Swiss-Prot
Match: MTHR2_ARATH (Methylenetetrahydrofolate reductase 2 OS=Arabidopsis thaliana GN=MTHFR2 PE=1 SV=2)

HSP 1 Score: 290.041 bits (741), Expect = 4.048e-89
Identity = 135/159 (84.91%), Postives = 143/159 (89.94%), Query Frame = 2

Query:  167 MKVIDKIQEKVASDKVVFSFEFFPPKTEDGVENLFERMDRMVAHNPAFCDITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIRGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPD 643
            MKVIDKIQ      K  FSFEFFPPKTEDGV+NLFERMDRMVA+ P FCDITWGAGGSTADLTLDIA+RMQN +CVE+MMHLTCTNMPVEKIDHAL+TI+SNGIQNVLALRGDPPHGQDKFVQ+ GGF CALDLV HIRS YGDYFGITVAGYPE HPD
Sbjct:    1 MKVIDKIQSLADEGKTAFSFEFFPPKTEDGVDNLFERMDRMVAYGPTFCDITWGAGGSTADLTLDIASRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGQDKFVQVEGGFDCALDLVNHIRSKYGDYFGITVAGYPEAHPD 159          

HSP 2 Score: 60.4622 bits (145), Expect = 4.048e-89
Identity = 35/81 (43.21%), Postives = 45/81 (55.56%), Query Frame = 1

Query:  661 GWAVMNHIKSDLLYLKKKVDAGGDLITTQRCYETGLSSKCVKNGRHMGMTCPHGRGNEAHKDA*GVLGPCGRCANKIPPEI 903
            G A     +SDL YLKKK+DAG DLI TQ  Y+T +  K V + R +G++CP   G     +  G L   G C  KIP E+
Sbjct:  165 GLASNEAYQSDLEYLKKKIDAGADLIVTQLFYDTDIFLKFVNDCRQIGISCPIVPGIMPINNYRGFLRMTGFCKTKIPVEV 245          

BLAST of EY720487 vs. ExPASy Swiss-Prot
Match: MTHR2_YEAST (Methylenetetrahydrofolate reductase 2 OS=Saccharomyces cerevisiae GN=MET13 PE=1 SV=2)

HSP 1 Score: 167.548 bits (423), Expect = 5.236e-46
Identity = 83/162 (51.23%), Postives = 110/162 (67.90%), Query Frame = 2

Query:  167 MKVIDKI-QEKVASDKVVFSFEFFPPKTEDGVENLFERMDRMV-AHNPAFCDITWGAGGST-ADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIRGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPD 643
            MK+ +K+ Q +  S K  +SFE+F PKT  GV+NL++RMDRM  A  P F DITW AGG   + L+ D+    Q+ + +ET MHLTCTNMP+  ID AL+    +G QN+LALRGDPP   + +  + GGF  A DL+K+I+S YGD+F I VAGYPE HP+
Sbjct:    1 MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGGRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRDAENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPE 162          

HSP 2 Score: 38.891 bits (89), Expect = 5.236e-46
Identity = 20/45 (44.44%), Postives = 24/45 (53.33%), Query Frame = 1

Query:  682 IKSDLLYLKKKVDAGGDLITTQRCYETGLSSKCVKNGRHMGMTCP 816
            +K DL YLK+K+DAGGD I TQ  Y+           R  GM  P
Sbjct:  168 VKLDLEYLKQKIDAGGDFIITQMFYDVDNFINWCSQVRAAGMDVP 212          

BLAST of EY720487 vs. ExPASy Swiss-Prot
Match: MTHR_MACFA (Methylenetetrahydrofolate reductase OS=Macaca fascicularis GN=MTHFR PE=2 SV=1)

HSP 1 Score: 136.732 bits (343), Expect = 2.844e-37
Identity = 70/159 (44.03%), Postives = 98/159 (61.64%), Query Frame = 2

Query:  179 DKIQEKVASDKVVFSFEFFPPKTEDGVENLFERMDRMVAHNPAFCDITWGAGGSTAD----LTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIRGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPD 643
            DK++ ++ S    FS EFFPP+T +G  NL  R DRM A  P F D+TW   G         ++ IA+   N   +ET++H+TC    +E+I   L   K  G++N++ALRGDP    D++ +  GGF  A+DLVKHIRS +GDYF + VAGYP+GHP+
Sbjct:   47 DKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQRLEEITGHLHKAKQLGLKNIMALRGDPIG--DQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPKGHPE 203          

HSP 2 Score: 40.4318 bits (93), Expect = 2.844e-37
Identity = 20/44 (45.45%), Postives = 27/44 (61.36%), Query Frame = 1

Query:  685 KSDLLYLKKKVDAGGDLITTQRCYETGLSSKCVKNGRHMGMTCP 816
            ++DL +LK+KV AG D I TQ  +E     + VK    MG+TCP
Sbjct:  208 EADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCP 251          

BLAST of EY720487 vs. ExPASy Swiss-Prot
Match: MTHR1_YEAST (Methylenetetrahydrofolate reductase 1 OS=Saccharomyces cerevisiae GN=MET12 PE=1 SV=2)

HSP 1 Score: 144.436 bits (363), Expect = 3.704e-37
Identity = 74/141 (52.48%), Postives = 92/141 (65.25%), Query Frame = 2

Query:  221 SFEFFPPKTEDGVENLFERMDRMVAHNPAFCDITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQD--KFVQIRGGFACALDLVKHIRSAYGDYFGITVAGYPEGH 637
            S EFFPPKTE G  NL ERM RM A +P F  +TWGAGG+TA+ TL +A+  Q T+ +   MHLTCTN     ID AL    + GI+N+LALRGDPP G+D          F  A+DLV++I+ +YGD F + VA YPEGH
Sbjct:   16 SLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKTLTLASLAQQTLNIPVCMHLTCTNTEKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDSQSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGH 156          

HSP 2 Score: 32.3426 bits (72), Expect = 3.704e-37
Identity = 13/23 (56.52%), Postives = 18/23 (78.26%), Query Frame = 1

Query:  691 DLLYLKKKVDAGGDLITTQRCYE 759
            DL+YLK+KV+AG D + TQ  Y+
Sbjct:  171 DLVYLKEKVEAGADFVITQLFYD 193          

BLAST of EY720487 vs. ExPASy Swiss-Prot
Match: MTHR1_SCHPO (Methylenetetrahydrofolate reductase 1 OS=Schizosaccharomyces pombe GN=met9 PE=1 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 4.689e-37
Identity = 82/161 (50.93%), Postives = 106/161 (65.84%), Query Frame = 2

Query:  167 MKVIDKIQEKVASDKVVFSFEFFPPKTEDGVENLFERMDRMVAHN-PAFCDITWGAGGSTADLTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIRGGFACALDLVKHIRSAYGDYFGITVAGYPEGH-PD 643
            MK+ DK+      +KV +S+EFFPPKT  GV+NL+ R+DRM     P F D+TWGAGG++++LT  I N +Q    V+T MHLTCTNM  E ID AL+     G +N+LALRGDP    D + +   GF  A DLV++IR+ Y D F I VAGYPEG+ PD
Sbjct:    1 MKISDKLLHPDWKEKVTYSYEFFPPKTSTGVQNLYNRIDRMKTWGRPMFVDVTWGAGGTSSELTPGIVNVIQTDFEVDTCMHLTCTNMSTEMIDAALKRAHETGCRNILALRGDPVKDTD-WTEGESGFRYASDLVRYIRTHYNDEFCIGVAGYPEGYSPD 160          

BLAST of EY720487 vs. ExPASy Swiss-Prot
Match: MTHR_HUMAN (Methylenetetrahydrofolate reductase OS=Homo sapiens GN=MTHFR PE=1 SV=3)

HSP 1 Score: 135.961 bits (341), Expect = 4.825e-37
Identity = 69/159 (43.40%), Postives = 98/159 (61.64%), Query Frame = 2

Query:  179 DKIQEKVASDKVVFSFEFFPPKTEDGVENLFERMDRMVAHNPAFCDITWGAGGSTAD----LTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIRGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPD 643
            +K++ ++ S    FS EFFPP+T +G  NL  R DRM A  P + D+TW   G         ++ IA+   N   +ET++H+TC    +E+I   L   K  G++N++ALRGDP    D++ +  GGF  A+DLVKHIRS +GDYF I VAGYP+GHP+
Sbjct:   47 EKMRRRLESGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIG--DQWEEEEGGFNYAVDLVKHIRSEFGDYFDICVAGYPKGHPE 203          

HSP 2 Score: 40.4318 bits (93), Expect = 4.825e-37
Identity = 20/44 (45.45%), Postives = 27/44 (61.36%), Query Frame = 1

Query:  685 KSDLLYLKKKVDAGGDLITTQRCYETGLSSKCVKNGRHMGMTCP 816
            ++DL +LK+KV AG D I TQ  +E     + VK    MG+TCP
Sbjct:  208 EADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCP 251          

BLAST of EY720487 vs. ExPASy Swiss-Prot
Match: MTHR_BOVIN (Methylenetetrahydrofolate reductase OS=Bos taurus GN=MTHFR PE=2 SV=1)

HSP 1 Score: 133.65 bits (335), Expect = 1.152e-35
Identity = 70/159 (44.03%), Postives = 96/159 (60.38%), Query Frame = 2

Query:  179 DKIQEKVASDKVVFSFEFFPPKTEDGVENLFERMDRMVAHNPAFCDITWGAGGSTAD----LTLDIANRMQNTICVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQIRGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPD 643
            +K++ K+ S    FS EFFPP+T  G  NL  R DRM A  P F D+TW   G         ++ IA+   N   +ET++H+TC +   E+I   L   K  G++N+LALRGDP    D++ +  GGF  A DLVKHIR+ +GDYF + VAGYP+GHP+
Sbjct:   46 EKMKRKMDSGDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPIG--DQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKGHPE 202          

HSP 2 Score: 38.1206 bits (87), Expect = 1.152e-35
Identity = 19/44 (43.18%), Postives = 27/44 (61.36%), Query Frame = 1

Query:  685 KSDLLYLKKKVDAGGDLITTQRCYETGLSSKCVKNGRHMGMTCP 816
            ++DL +LK+KV AG D I TQ  +E     + VK    +G+TCP
Sbjct:  207 EADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCP 250