EY720367

BLAST of EY720367 vs. ExPASy Swiss-Prot
Match: HERC2_HUMAN (Probable E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens GN=HERC2 PE=1 SV=1)

HSP 1 Score: 81.2629 bits (199), Expect = 7.907e-15
Identity = 57/193 (29.53%), Postives = 85/193 (44.04%), Query Frame = 3

Query:  156 QVLSWGRGASGQLGVGTEESGLYPGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHS---GLVVNGKLWIWGKGDGGRLGFGHEDAAFVPTLNPYLDD-PVRGIALGGVHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMATSGMHTAAITQSGELYTW 722
            ++ +WGRG  G+LG G+ E    P  VA L                          G   I ++CG   +    +  NG++W WG GD G+LG G  D    P L   L D  V  +  G   S+ALT  GQ+++      G G    LGH       +PKL+EG   +++  +A    H  A+T+  E+++W
Sbjct:  571 ELYTWGRGNYGRLGHGSSEDEAIPMLVAGL-------------------------KGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQFSIALTKDGQVYS-----WGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSW 733          

HSP 2 Score: 68.9366 bits (167), Expect = 4.061e-11
Identity = 54/190 (28.42%), Postives = 78/190 (41.05%), Query Frame = 3

Query:  165 SWGRGASGQLGVGTEESGLYPGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHSG---LVVNGKLWIWGKGDGGRLGFGHEDAAFVPT-LNPYLDDPVRGIALGGVHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMATSGMHTAAITQSGELYTW 722
            +WG+G  G+LG    E  L P  V  L                          G   + I+CG   +    L  +  +W WG GD G+LG G  D   VP  ++      V  +  G   SVALT  G ++T      G G +  LGH        P+ V+G   +++  +AT  +H    T+ GE+YTW
Sbjct: 4114 TWGKGRYGRLGHSDSEDQLKPKLVEAL-------------------------QGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYT-----WGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTW 4273          

HSP 3 Score: 68.5514 bits (166), Expect = 5.304e-11
Identity = 55/197 (27.92%), Postives = 91/197 (46.19%), Query Frame = 3

Query:  144 AVTLQVLSWGRGASGQLGVGTEESGLYPGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHSGLVV-NGKLWIWGKGDGGRLGFGHEDAAFVPTLNPYLDD-PVRGIALGG--VHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMATSGMHTAAITQSGELYTW 722
            A T +V SWG G  G+LG G             + L EP  ++   GK          + G+  + I+CG  +S  +   G+L+ WG+G+ GRLG G  +   +P L   L    V  +A G     ++A+T  GQ+++      G G +G LG         PKL+E   + ++  +      + A+T+ G++Y+W
Sbjct:  511 AATGEVYSWGCGDGGRLGHGD-----------TVPLEEPKVISAFSGK----------QAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWS-----WGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQFSIALTKDGQVYSW 681          

HSP 4 Score: 67.781 bits (164), Expect = 9.047e-11
Identity = 55/193 (28.50%), Postives = 83/193 (43.01%), Query Frame = 3

Query:  156 QVLSWGRGASGQLGVGTEESGLYPGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHS---GLVVNGKLWIWGKGDGGRLGFGHEDAAFVPTLNPYLDDP-VRGIALGGVHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMATSGMHTAAITQSGELYTW 722
            ++ +WG G  G+LG G   + L P  V  L+                         G   I ++CG   +    L   G ++ WG GD G+LG G  +   +P     L+   V  I  G   S+ALT  G ++T      G G +  LGH        P++VEG   ++I H+A   +H  A+T SG++Y W
Sbjct: 3119 ELYTWGLGEYGRLGHGDNTTQLKPKMVKVLL-------------------------GHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWT-----WGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAW 3281          

BLAST of EY720367 vs. ExPASy Swiss-Prot
Match: HERC2_MOUSE (Probable E3 ubiquitin-protein ligase HERC2 OS=Mus musculus GN=Herc2 PE=1 SV=2)

HSP 1 Score: 79.7221 bits (195), Expect = 2.301e-14
Identity = 56/193 (29.02%), Postives = 84/193 (43.52%), Query Frame = 3

Query:  156 QVLSWGRGASGQLGVGTEESGLYPGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHS---GLVVNGKLWIWGKGDGGRLGFGHEDAAFVPTLNPYLDD-PVRGIALGGVHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMATSGMHTAAITQSGELYTW 722
            ++ +WGRG  G+LG G+ E    P  VA L                          G   I ++CG   +    +  NG++W WG GD G+LG G  D    P L   L D  V  +  G   S+ALT  GQ+++      G G    LGH       +PKL+EG   +++  +A    H   +T+  E+++W
Sbjct:  572 ELYTWGRGNYGRLGHGSSEDEAIPMLVAGL-------------------------KGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYS-----WGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLVLTEDSEVHSW 734          

HSP 2 Score: 69.3218 bits (168), Expect = 3.109e-11
Identity = 55/190 (28.95%), Postives = 78/190 (41.05%), Query Frame = 3

Query:  165 SWGRGASGQLGVGTEESGLYPGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHSG---LVVNGKLWIWGKGDGGRLGFGHEDAAFVPT-LNPYLDDPVRGIALGGVHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMATSGMHTAAITQSGELYTW 722
            +WG+G  G+LG    E  L P  V  L                          G   I I+CG   +    L  +  +W WG GD G+LG G  D   VP  ++      V  +  G   SVALT  G ++T      G G +  LGH        P+ V+G   +++  +AT  +H    T+ GE+YTW
Sbjct: 4116 TWGKGRYGRLGHSDSEDQLKPKLVEAL-------------------------QGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYT-----WGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTW 4275          

HSP 3 Score: 68.1662 bits (165), Expect = 6.927e-11
Identity = 55/197 (27.92%), Postives = 91/197 (46.19%), Query Frame = 3

Query:  144 AVTLQVLSWGRGASGQLGVGTEESGLYPGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHSGLVV-NGKLWIWGKGDGGRLGFGHEDAAFVPTLNPYLDD-PVRGIALGG--VHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMATSGMHTAAITQSGELYTW 722
            A T +V SWG G  G+LG G             + L EP  ++   GK          + G+  + I+CG  +S  +   G+L+ WG+G+ GRLG G  +   +P L   L    V  +A G     ++A+T  GQ+++      G G +G LG         PKL+E   + ++  +      + A+T+ G++Y+W
Sbjct:  512 AATGEVYSWGCGDGGRLGHGD-----------TVPLEEPKVISAFSGK----------QAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWS-----WGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSW 682          

HSP 4 Score: 67.781 bits (164), Expect = 9.047e-11
Identity = 55/193 (28.50%), Postives = 83/193 (43.01%), Query Frame = 3

Query:  156 QVLSWGRGASGQLGVGTEESGLYPGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHS---GLVVNGKLWIWGKGDGGRLGFGHEDAAFVPTLNPYLDDP-VRGIALGGVHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMATSGMHTAAITQSGELYTW 722
            ++ +WG G  G+LG G   + L P  V  L+                         G   I ++CG   +    L   G ++ WG GD G+LG G  +   +P     L+   V  I  G   S+ALT  G ++T      G G +  LGH        P++VEG   ++I H+A   +H  A+T SG++Y W
Sbjct: 3120 ELYTWGLGEYGRLGHGDNTTQLKPKMVKVLL-------------------------GHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWT-----WGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAW 3282          

BLAST of EY720367 vs. ExPASy Swiss-Prot
Match: HERC1_HUMAN (Probable E3 ubiquitin-protein ligase HERC1 OS=Homo sapiens GN=HERC1 PE=1 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 3.005e-14
Identity = 57/190 (30.00%), Postives = 88/190 (46.32%), Query Frame = 3

Query:  156 QVLSWGRGASGQLGVGTEESGLYPGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHSGLVV-NGKLWIWGKGDGGRLGFGHEDAAFVPTLNPYLDDPVRGIALGGVHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMATSGMHTAAITQSGELYTW 722
            +V SWG G  G+LG G   +  YP             L Q P              G+V + +S G  HS  V  +G+L+ WG+GD GRLG G  ++  +PTL   + + V  ++ G  H++AL+  G+         G G  G LGH   +R   PK++E      I+ +      + A+T +G++Y W
Sbjct:  478 EVFSWGDGDYGKLGHGNSSTQKYPK------------LIQGP------------LQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISN-VGEVSCGSSHTIALSKDGRTVW----SFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAW 638          

HSP 2 Score: 69.3218 bits (168), Expect = 3.109e-11
Identity = 60/198 (30.30%), Postives = 90/198 (45.45%), Query Frame = 3

Query:  150 TLQVLSWGRGASGQLGVGTEESGLYPGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHSGLVVNGKLWIWGKGDGGRLGFGHEDAAFVPTLNPYLDDPVRGIAL------GGVHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMATSG-MHTAAITQSGELYTW 722
            T +V  WG  +S QL  GT+E  L P       L+  +  AQT                 ++ G  C    S    +G +   GKG  GRLG G  D+    TL     +P R I           H++A T+ G++F+      G G +G LGH     + +PKL++G  + ++    ++G  H+AA+T+ GELYTW
Sbjct:  371 TCEVYVWGSNSSHQLVEGTQEKILQPK------LAPSFSDAQT-----------------IEAGQYCTFVIS---TDGSVRACGKGSYGRLGLG--DSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFS-----WGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTW 535          

BLAST of EY720367 vs. ExPASy Swiss-Prot
Match: HERC2_DROME (Probable E3 ubiquitin-protein ligase HERC2 OS=Drosophila melanogaster GN=HERC2 PE=1 SV=3)

HSP 1 Score: 75.485 bits (184), Expect = 4.339e-13
Identity = 59/193 (30.57%), Postives = 81/193 (41.97%), Query Frame = 3

Query:  159 VLSWGRGASGQLGVGTEESGLYPGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHSGLVVNGKLWIWGKGDGGRLGFGHEDAAFVPTLNPYLDDPVRGIAL-----GGVHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMATSGMHTAAITQSGELYTW 722
            VL+WG+G  G+LG G  E  L P  V  L+      +A   G   + C  D                      +  +W WG GD G+LG G  D   +P    Y  + + G+ +     G   SVALT  G ++T      G G F  LGH        PK V     ++I  +AT  +H  A + SGE+YTW
Sbjct: 4209 VLTWGKGRYGRLGHGDSEDQLRPKLVEALLGYRAIDIACGSGDAQTLCITD----------------------DDNVWSWGDGDYGKLGRGGSDGCKLP----YKIESLAGLGVVKVECGSQFSVALTKSGAVYT-----WGKGDFHRLGHGSVDHVRRPKKVAALQGKKIISIATGSLHCVACSDSGEVYTW 4370          

HSP 2 Score: 70.8626 bits (172), Expect = 1.069e-11
Identity = 57/193 (29.53%), Postives = 85/193 (44.04%), Query Frame = 3

Query:  159 VLSWGRGASGQLGVGTEESGLYPGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHS-GLVVNGKLWIWGKGDGGRLGFGHEDAAFVPTLNPYLDDPVRGIALGGVHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHREL----FPKLVEGAWEREIKHMATSGMHTAAITQSGELYTW 722
            +L+WGRG   +LG G  +    P  V  L                       + +  VD+ +  G  HS  L   G ++ WG GD G+LG G+ + +  P L   L   V+ +  G   SVAL+S GQL+T       +G    LGH +  R +     P+LV     + I  +A S  H  A++ SGE++ W
Sbjct:  689 LLTWGRGTYARLGHGNSDDRSLPTLVVAL-----------------------SDHMVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILVESLPR-VQRVFAGSQFSVALSSEGQLYT-------WGKATCLGHQLVERSVQGCSVPRLVSSLQHKRIVDVAVSVAHCLALSSSGEVFGW 850          

HSP 3 Score: 69.3218 bits (168), Expect = 3.109e-11
Identity = 44/130 (33.85%), Postives = 68/130 (52.31%), Query Frame = 3

Query:  360 HSG------LVVNGKLWIWGKGDGGRLGFGHEDAAFVPTLNPYL-DDPVRGIALGGVHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMA--TSGMHTAAITQSGELYTW 722
            HSG      L ++GK++ WG+G+ G+LG G+      P L   L    +R +A G  HS A++S G+L+T      G G +G LGH     +L PKLV     R +  +A  +    T A+T+ G +++W
Sbjct: 3079 HSGGKHALALTLDGKVFSWGEGEDGKLGHGNRTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYT-----WGLGEYGRLGHGDNTTQLKPKLVTALAGRRVVQVACGSRDAQTLALTEDGAVFSW 3203          

HSP 4 Score: 68.9366 bits (167), Expect = 4.061e-11
Identity = 65/192 (33.85%), Postives = 84/192 (43.75%), Query Frame = 3

Query:  159 VLSWGRGASGQLGVGTEESGLY-PGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHSGLVVNGKLWIWGKGDGGRLGFGHEDAAFVPTLNPYLDDP-VRGIAL--GGVHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMATSGMHTAAITQSGELYTW 722
            +  WG    GQLG G E S +  P P   L L  P  LA                      G    LF   +  +GKL+  G G GGRLG G  D+  +PTL   L    V+ +A+  GG H +ALT+ G+++       G G  G LGH        PKLVE      +  +A    H+AAIT SG + TW
Sbjct: 4051 IYGWGHNHRGQLG-GLEGSRIKTPTPCEALSLLRPVQLA----------------------GGEQSLF--AVTPDGKLFATGYGSGGRLGVGGSDSWAIPTLLGSLQHVFVKKVAVNSGGKHCLALTTEGEVY-----AWGEGEDGKLGHGNRMSYDRPKLVEHLNGMSVADIACGSAHSAAITASGHVLTW 4212          

BLAST of EY720367 vs. ExPASy Swiss-Prot
Match: HERC5_HUMAN (Probable E3 ubiquitin-protein ligase HERC5 OS=Homo sapiens GN=HERC5 PE=1 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 8.182e-12
Identity = 59/192 (30.73%), Postives = 87/192 (45.31%), Query Frame = 3

Query:  156 QVLSWGRGASGQLGVGTEESGLYPGPVANLILSEPYFLAQTPGKLVSDCNHDWNKNGEVDIGISCGLFHS-GLVVNGKLWIWGKGDGGRLGFGHEDAAFVPTLNPYLDDP-VRGIALGGVHSVALTSLGQLFT*NEVCRGYGGFGALGHSVYHRELFPKLVEGAWEREIKHMATSGMHTAA-ITQSGELYTW 722
            ++ +WG+   GQLGVG +        +   +   P  LAQ                      IS G  HS  L ++G ++ WGK + G+LG GH ++   P+L   LD+  V  +A GG HS  LT  G LFT      G G  G LGH+    EL P LV       +  +A    HT A ++  G+++++
Sbjct:  158 ELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVP--LAQ----------------------ISAGEAHSMALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQDGLLFT-----FGAGKHGQLGHNSTQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSF 320