EY711207

BLAST of EY711207 vs. ExPASy Swiss-Prot
Match: EDEM2_HUMAN (ER degradation-enhancing alpha-mannosidase-like 2 OS=Homo sapiens GN=EDEM2 PE=1 SV=2)

HSP 1 Score: 196.052 bits (497), Expect = 5.547e-51
Identity = 99/202 (49.01%), Postives = 140/202 (69.31%), Query Frame = 1

Query:   79 TAEEARQLRDEVREMFYHAFDGYMEHAFPLDELRPLSCEGEDSLGGYALTLVDSLDTLALLGDRERFTTSVEWIGKNLQFDINKTVSVFETTIRVLGGLLSAHLIASDYATGMKIPS---YDNQLLNLAEDLAQRLLPAFDTPTGIPFGSVNLLHGVDEHESKITSTAGGGTLTLEI*VLSRLTNDPIFEQLQR---KQCWE 666
            +A +    R+ V+ MFYHA+D Y+E+AFP DELRPL+C+G D+ G ++LTL+D+LDTL +LG+   F   VE +  ++ FDI+   SVFET IRV+GGLLSAHL++     G+++ +       LL +AE+ A++LLPAF TPTG+P+G+VNLLHGV+  E+ +T TAG GT  +E   LS LT DP+FE + R    + WE
Sbjct:   28 SAPDPAHYRERVKAMFYHAYDSYLENAFPFDELRPLTCDGHDTWGSFSLTLIDALDTLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSK--KAGVEVEAGWPCSGPLLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVALMRLWE 227          

HSP 2 Score: 26.5646 bits (57), Expect = 5.547e-51
Identity = 12/32 (37.50%), Postives = 18/32 (56.25%), Query Frame = 2

Query:  737 EDAGIGTSXDSXYEDLLKAYPIFCDEEYCTFF 832
            +DAGIG   DS +E L+K   +  D++    F
Sbjct:  249 QDAGIGAGVDSYFEYLVKGAILLQDKKLMAMF 280          

BLAST of EY711207 vs. ExPASy Swiss-Prot
Match: MNL1_SCHPO (ER degradation-enhancing alpha-mannosidase-like protein 1 OS=Schizosaccharomyces pombe GN=mnl1 PE=2 SV=2)

HSP 1 Score: 172.555 bits (436), Expect = 4.585e-46
Identity = 93/206 (45.15%), Postives = 125/206 (60.68%), Query Frame = 1

Query:   61 SLADGVTAEEARQLRDEVREMFYHAFDGYMEHAFPLDELRPLSCEG-------------EDSLGGYALTLVDSLDTLALLGDRERFTTSVEWIGKNLQFDINKTVSVFETTIRVLGGLLSAHLIASDYATGMKIPSYDNQLLNLAEDLAQRLLPAFDTPTGIPFGSVNLLHGVDEHESKITSTAGGGTLTLEI*VLSRLTNDPIFE 639
            S+   + +    +LR+  R +FYH ++ YM+ AFP DEL PLSCEG              D  G Y LTLVD LDTL +LGDRE F  +V+ +  ++ F+ +  V VFE TIR+LGGLLS+H+ AS+   G +IP Y  +LL LA +LA+RLLPAF TPTGIPF  +NL+ GV   E      A   +L LE  +L+ LT +  F+
Sbjct:   22 SIVGAINSARMVELRETSRRLFYHGYNNYMQFAFPNDELAPLSCEGLGPDYENPNNIGVNDVRGDYLLTLVDVLDTLVVLGDREGFQDAVDKVIHHINFERDTKVQVFEATIRILGGLLSSHIFASEEKYGFQIPLYKGELLTLATELAERLLPAFRTPTGIPFARINLMKGVAYREVTENCAAAASSLVLEFSMLTALTGNNKFK 227          

HSP 2 Score: 30.0314 bits (66), Expect = 4.585e-46
Identity = 11/28 (39.29%), Postives = 17/28 (60.71%), Query Frame = 3

Query:  648 KKAVLGIWARRSKLNLVGAHINVFTGEW 731
            + A   +W RRS + L+G  I+V +G W
Sbjct:  231 ENAFFSVWKRRSGIGLLGNSIDVLSGRW 258          

HSP 3 Score: 24.2534 bits (51), Expect = 4.585e-46
Identity = 10/26 (38.46%), Postives = 13/26 (50.00%), Query Frame = 2

Query:  743 AGIGTSXDSXYEDLLKAYPIFCDEEY 820
            +G+G   DS YE   K+Y    D  Y
Sbjct:  263 SGVGAGIDSFYEYAFKSYIFLGDPRY 288          

BLAST of EY711207 vs. ExPASy Swiss-Prot
Match: EDEM1_HUMAN (ER degradation-enhancing alpha-mannosidase-like 1 OS=Homo sapiens GN=EDEM1 PE=1 SV=1)

HSP 1 Score: 169.474 bits (428), Expect = 5.773e-44
Identity = 98/203 (48.28%), Postives = 122/203 (60.10%), Query Frame = 1

Query:   97 QLRDEVREMFYHAFDGYMEHAFPLDELRPLSCEGE-------------DSLGGYALTLVDSLDTLALLGDRERFTTSVEWIGKNLQFDINKTVSVFETTIRVLGGLLSAHLIASDYAT---GMKIPSYDNQLLNLAEDLAQRLLPAFD-TPTGIPFGSVNLLHGVDEHESKITSTAGGGTLTLEI*VLSRLTNDPIFEQLQRK 654
            Q+RD  R MF   +D YM HAFP DEL P+ C G              D LG Y+LTLVD+LDTLA++G+   F  +V+ +   + FD + TV VFE TIRVLG LLSAH I +D       M I  YDN+LL +A DLA RLLPAF+ T TGIP+  VNL  GV    +  T TAG G+L +E  +LSRL  D  FE + R+
Sbjct:  129 QMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNETCTAGAGSLLVEFGILSRLLGDSTFEWVARR 331          

HSP 2 Score: 29.6462 bits (65), Expect = 5.773e-44
Identity = 13/32 (40.62%), Postives = 20/32 (62.50%), Query Frame = 2

Query:  737 EDAGIGTSXDSXYEDLLKAYPIFCDEEYCTFF 832
            + +G+G   DS YE LLK+Y +F ++E    F
Sbjct:  361 KQSGLGAGLDSFYEYLLKSYILFGEKEDLEMF 392          

BLAST of EY711207 vs. ExPASy Swiss-Prot
Match: EDEM1_MOUSE (ER degradation-enhancing alpha-mannosidase-like 1 OS=Mus musculus GN=Edem1 PE=2 SV=1)

HSP 1 Score: 169.474 bits (428), Expect = 5.774e-44
Identity = 98/203 (48.28%), Postives = 122/203 (60.10%), Query Frame = 1

Query:   97 QLRDEVREMFYHAFDGYMEHAFPLDELRPLSCEGE-------------DSLGGYALTLVDSLDTLALLGDRERFTTSVEWIGKNLQFDINKTVSVFETTIRVLGGLLSAHLIASDYAT---GMKIPSYDNQLLNLAEDLAQRLLPAFD-TPTGIPFGSVNLLHGVDEHESKITSTAGGGTLTLEI*VLSRLTNDPIFEQLQRK 654
            Q+RD  R MF   +D YM HAFP DEL P+ C G              D LG Y+LTLVD+LDTLA++G+   F  +V+ +   + FD + TV VFE TIRVLG LLSAH I +D       M I  YDN+LL +A DLA RLLPAF+ T TGIP+  VNL  GV    +  T TAG G+L +E  +LSRL  D  FE + R+
Sbjct:  124 QMRDLARGMFVFGYDNYMAHAFPQDELNPIYCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIEDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDSNNETCTAGAGSLLVEFGILSRLLGDSTFEWVARR 326          

HSP 2 Score: 29.6462 bits (65), Expect = 5.774e-44
Identity = 13/32 (40.62%), Postives = 20/32 (62.50%), Query Frame = 2

Query:  737 EDAGIGTSXDSXYEDLLKAYPIFCDEEYCTFF 832
            + +G+G   DS YE LLK+Y +F ++E    F
Sbjct:  356 KQSGLGAGLDSFYEYLLKSYILFGEKEDLEMF 387          

BLAST of EY711207 vs. ExPASy Swiss-Prot
Match: EDEM3_MOUSE (ER degradation-enhancing alpha-mannosidase-like 3 OS=Mus musculus GN=Edem3 PE=1 SV=2)

HSP 1 Score: 163.31 bits (412), Expect = 4.783e-43
Identity = 99/253 (39.13%), Postives = 145/253 (57.31%), Query Frame = 1

Query:   52 ICRSLADGVTAEEARQLRDEVREMFYHAFDGYMEHAFPLDELRPLSCEG------------EDSLGGYALTLVDSLDTLALLGDRERFTTSVEWIGKNLQFDINKTVSVFETTIRVLGGLLSAHLIASDY-ATGMKIPSYDNQLLNLAEDLAQRLLPAFDTPTGIPFGSVNLLHGVDEHESKI-----TSTAGGGTLTLEI*VLSRLTNDPIFEQLQRKQ---CWEFGHAVQNLI*LALTLMCLQVNGHRGCW 747
            +C + A  ++ EE ++L ++V EMF HA+  YMEHA+P DEL PL+C G            +D+LG ++LTL+DSLDTL +L   + F  +V  + +++  D +  VSVFET IRVLGGLL  H +A      G  +  Y+++LL++A+ L  +LLPAF+T +G+P+  +NL  G+ + E++      T TA  GTL LE   LSR T   IFE+  RK     WE      NL+        + +N H G W
Sbjct:   37 VCTAGAAPMSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKFSLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAIMLKEKGEHMQWYNDELLHMAKQLGYKLLPAFNTTSGLPYPRINLKFGIRKPEARTGTETDTCTACAGTLILEFAALSRFTGATIFEEYARKALDFLWEKRQRSSNLV-------GVTINIHTGDW 282          

HSP 2 Score: 32.7278 bits (73), Expect = 4.783e-43
Identity = 14/32 (43.75%), Postives = 20/32 (62.50%), Query Frame = 2

Query:  737 EDAGIGTSXDSXYEDLLKAYPIFCDEEYCTFF 832
            +D+G+G   DS YE LLKAY +  D+ +   F
Sbjct:  285 KDSGVGAGIDSYYEYLLKAYVLLGDDSFLERF 316          

BLAST of EY711207 vs. ExPASy Swiss-Prot
Match: EDEM3_HUMAN (ER degradation-enhancing alpha-mannosidase-like 3 OS=Homo sapiens GN=EDEM3 PE=1 SV=2)

HSP 1 Score: 160.999 bits (406), Expect = 2.341e-42
Identity = 98/248 (39.52%), Postives = 142/248 (57.26%), Query Frame = 1

Query:   67 ADGVTAEEARQLRDEVREMFYHAFDGYMEHAFPLDELRPLSCEG------------EDSLGGYALTLVDSLDTLALLGDRERFTTSVEWIGKNLQFDINKTVSVFETTIRVLGGLLSAHLIASDY-ATGMKIPSYDNQLLNLAEDLAQRLLPAFDTPTGIPFGSVNLLHGVDEHESKI-----TSTAGGGTLTLEI*VLSRLTNDPIFEQLQRKQ---CWEFGHAVQNLI*LALTLMCLQVNGHRGCW 747
            A+ ++ EE ++L ++V EMF HA+  YMEHA+P DEL PL+C G            +D+LG ++LTL+DSLDTL +L   + F  +V  + +++  D +  VSVFET IRVLGGLL  H +A      G  +  Y+++LL +A+ L  +LLPAF+T +G+P+  +NL  G+ + E++      T TA  GTL LE   LSR T   IFE+  RK     WE      NL+        + +N H G W
Sbjct:   41 AEPMSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKFSLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAIMLKEKGEYMQWYNDELLQMAKQLGYKLLPAFNTTSGLPYPRINLKFGIRKPEARTGTETDTCTACAGTLILEFAALSRFTGATIFEEYARKALDFLWEKRQRSSNLV-------GVTINIHTGDW 281          

HSP 2 Score: 32.7278 bits (73), Expect = 2.341e-42
Identity = 14/32 (43.75%), Postives = 20/32 (62.50%), Query Frame = 2

Query:  737 EDAGIGTSXDSXYEDLLKAYPIFCDEEYCTFF 832
            +D+G+G   DS YE LLKAY +  D+ +   F
Sbjct:  284 KDSGVGAGIDSYYEYLLKAYVLLGDDSFLERF 315          

BLAST of EY711207 vs. ExPASy Swiss-Prot
Match: EDEM3_XENLA (ER degradation-enhancing alpha-mannosidase-like 3 OS=Xenopus laevis GN=edem3 PE=2 SV=2)

HSP 1 Score: 157.918 bits (398), Expect = 6.751e-42
Identity = 96/247 (38.87%), Postives = 140/247 (56.68%), Query Frame = 1

Query:   76 VTAEEARQLRDEVREMFYHAFDGYMEHAFPLDELRPLSCEG------------EDSLGGYALTLVDSLDTLALLGDRERFTTSVEWIGKNLQFDINKTVSVFETTIRVLGGLLSAHLIA---SDYATGMKIPSYDNQLLNLAEDLAQRLLPAFDTPTGIPFGSVNLLHGVDEHESKI-----TSTAGGGTLTLEI*VLSRLTNDPIFEQLQRKQ---CWEFGHAVQNLI*LALTLMCLQVNGHRGCW 747
            VT EE   LR +V EMF HA+  YM+HA+P DEL PL+C G            +D+LG ++LTL+D+LDTL +L   + F  +V  +  ++  D +  VSVFET IRVLGGLL  H +A    +   GM+   Y+++LL++A++L  +LLPAF+T +G+P+  +NL  G+   E++      T TA  GT+ LE   LSR T   +FE+  RK     W+      NL+        + +N H G W
Sbjct:   30 VTKEEKAHLRSQVLEMFDHAYGNYMQHAYPADELMPLTCRGRIRGQEPSRGDVDDALGKFSLTLIDTLDTLVVLNKTKEFEDAVRKVITDVNLDNDIVVSVFETNIRVLGGLLGGHSVAIMLKENGDGMQ--WYNDELLHMAKELGYKLLPAFNTTSGLPYPRINLKFGIRRPEARTGTETDTCTACAGTMILEFAALSRFTGISVFEEHARKALDFLWDKRQRSSNLV-------GVTINIHTGDW 267          

HSP 2 Score: 34.2686 bits (77), Expect = 6.751e-42
Identity = 15/32 (46.88%), Postives = 20/32 (62.50%), Query Frame = 2

Query:  737 EDAGIGTSXDSXYEDLLKAYPIFCDEEYCTFF 832
            +D+G+G   DS YE LLKAY +  D+ Y   F
Sbjct:  270 KDSGVGAGIDSYYEYLLKAYVLLGDDSYLERF 301          

BLAST of EY711207 vs. ExPASy Swiss-Prot
Match: MNL1_YEAST (ER degradation-enhancing alpha-mannosidase-like protein 1 OS=Saccharomyces cerevisiae GN=MNL1 PE=1 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 1.714e-34
Identity = 87/233 (37.34%), Postives = 131/233 (56.22%), Query Frame = 1

Query:   19 LVSILLSGNFFICRSLADGVTAEEARQLRDEVREMFYHAFDGYMEHAFPLDELRPLSC------------EG-EDSLGGYALTLVDSLDTLALLGDRERFTTSVEWIGKNL---QFDINKTVSVFETTIRVLGGLLSAHLIASDYATGMKI-PSYDNQLLNLAEDLAQRLLPAFDTPTGIPFGSVNLLHGVDEHE-----SKITSTAGGGTLTLEI*VLSRLTNDPIFEQLQR 651
            L+++LL  +   C   A   T++E +  + EV+E+FY  FD Y+EH +P DE++P+SC            +G  D LG + +TL+DSL T+A+L DR +F  +V  + +      FDI+ T+ VFE TIRV+G LLS+HL A+D    + +   YD  LL LA+++A RLLPA+ T TG+P    N+    D  E         + A   +   E  +LS LT DP +E++ R
Sbjct:    8 LLALLLHLDHVACEDDAYSFTSKELKAYKQEVKELFYFGFDNYLEHGYPYDEVKPISCVPKKRNFEDPTDQGTNDILGNFTITLIDSLTTIAILEDRPQFLKAVRLVERTFPDGNFDIDSTIQVFEITIRVIGSLLSSHLYATDPTKAVYLGDDYDGSLLRLAQNMADRLLPAYLTSTGLPMPRRNIKRKWDVSEFPEFLETENNVAAMASPMFEFTILSYLTGDPKYEKVTR 240          

BLAST of EY711207 vs. ExPASy Swiss-Prot
Match: MA1A1_MOUSE (Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Mus musculus GN=Man1a1 PE=1 SV=1)

HSP 1 Score: 117.472 bits (293), Expect = 1.114e-25
Identity = 74/190 (38.95%), Postives = 109/190 (57.37%), Query Frame = 1

Query:   94 RQLRDEVREMFYHAFDGYMEHAFPLDELRPLSCEGEDS--LGGY-ALTLVDSLDTLALLGDRERFTTSVEWIGKNLQFDINKTVSVFETTIRVLGGLLSAHLIASDYATGMKIPSYDNQLLNLAEDLAQRLLPAFDTPTGIPFGSVNLLHGVDEH----ESKITSTAGGGTLTLEI*VLSRLTNDPIFEQ 642
            R+ R +++EM  HA++ Y  +A+ L+EL+P+S EG  S   G     T+VD+LDTL ++G +  F  +  WI K L F++N  VSVFE  IR +GGLLSA+     Y +G +I          A +L  +LLPAF TP+GIP+  +N+  G+  +        +  A  GTL LE   LS L+ DP+F +
Sbjct:  195 REKRAKIKEMMTHAWNNYKRYAWGLNELKPISKEGHSSSLFGNIKGATIVDALDTLFIMGMKTEFQEAKSWIKKYLDFNVNAEVSVFEVNIRFVGGLLSAY-----YLSGEEI------FRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLSGDPVFAE 373          

BLAST of EY711207 vs. ExPASy Swiss-Prot
Match: MA1A2_MOUSE (Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Mus musculus GN=Man1a2 PE=2 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 1.900e-25
Identity = 73/188 (38.83%), Postives = 106/188 (56.38%), Query Frame = 1

Query:   88 EARQLRDEVREMFYHAFDGYMEHAFPLDELRPLSCEGEDS----LGGYALTLVDSLDTLALLGDRERFTTSVEWIGKNLQFDINKTVSVFETTIRVLGGLLSAHLIASDYATGMKIPSYDNQLLNLAEDLAQRLLPAFDTPTGIPFGSVNLLHGVDEH----ESKITSTAGGGTLTLEI*VLSRLTND 627
            E ++ RD+++EM  HA+D Y  + +  +ELRP++ +G  +          T+VD+LDTL ++G  + F     WI +NL F +N  VSVFE  IR +GGLL+A+     Y +G +I          A  LA++LLPAF+TPTGIP+  VNL  GV  +     +  +  A  GTL +E   LS LT D
Sbjct:  176 EIKKKRDKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSTNIFGSSQMGATIVDALDTLYIMGLHDEFMDGQRWIEENLDFSVNSEVSVFEVNIRFIGGLLAAY-----YLSGEEI------FKTKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFVHLSYLTGD 352