EY744653

BLAST of EY744653 vs. ExPASy Swiss-Prot
Match: HMCS_ARATH (Hydroxymethylglutaryl-CoA synthase OS=Arabidopsis thaliana GN=HMGS PE=2 SV=2)

HSP 1 Score: 226.098 bits (575), Expect = 1.999e-58
Identity = 121/183 (66.12%), Postives = 138/183 (75.41%), Query Frame = 1

Query:  208 MAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNGLLRRNCCII*LGELG*KVVPGKGAMGSLWGPNGAVYAKGPQDPLGGAPAGGHVKKGLEPPVAFEKKI 756
            MAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQ+C+AFC+E+EDVISMS  AVT+L EKYKIDP QIGRLEVGSETVIDKSKSIKTFLMQ+FEK GNTD+EGVDSTN        ++       +     G  G +   + AVYA+GP  P GGA A   +  G + P+ FE K+
Sbjct:    1 MAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQDCLAFCTELEDVISMSFNAVTSLFEKYKIDPNQIGRLEVGSETVIDKSKSIKTFLMQLFEKCGNTDVEGVDSTNACYGGTAALLNCVNWV-ESNSWDGRYGLVICTDSAVYAEGPARPTGGAAAIA-MLIGPDAPIVFESKL 181          

BLAST of EY744653 vs. ExPASy Swiss-Prot
Match: HMCS2_RAT (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Rattus norvegicus GN=Hmgcs2 PE=2 SV=1)

HSP 1 Score: 130.568 bits (327), Expect = 1.506e-36
Identity = 62/113 (54.87%), Postives = 83/113 (73.45%), Query Frame = 1

Query:  214 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTN 552
            K+VGILA+++YFP   V Q  LE  +    GKYT+GLGQ  M FCS  ED+ S+ LT V  L+E+ K+    +GRLEVG+ET+IDKSK++KT LM++F+  GNTDIEG+D+TN
Sbjct:   52 KDVGILALEVYFPAQYVDQTDLEKFNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERTKLPWDAVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTN 164          

HSP 2 Score: 44.2838 bits (103), Expect = 1.506e-36
Identity = 34/96 (35.42%), Postives = 49/96 (51.04%), Query Frame = 2

Query:  554 ACYGGTAALFNWVNWGEK*FL-GRALWGPCGDRTGRFMQKDRKTPWEEPLLVVMLKRAWSPPLLLKRKFKGGIYVPRAFNFLKPK-----PLVGGK 823
            ACYGGTA+LFN  NW E  +  GR     CGD         R T     + +++  +A   PL+L++  + G ++  A++F KP      PLV GK
Sbjct:  165 ACYGGTASLFNAANWMESSYWDGRYALVVCGDIAVYPSGNPRPTGGAGAVAMLIGPKA---PLVLEQGLR-GTHMENAYDFYKPNLASEYPLVDGK 256          

BLAST of EY744653 vs. ExPASy Swiss-Prot
Match: HMCS2_MOUSE (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Mus musculus GN=Hmgcs2 PE=1 SV=2)

HSP 1 Score: 130.568 bits (327), Expect = 1.962e-36
Identity = 62/113 (54.87%), Postives = 83/113 (73.45%), Query Frame = 1

Query:  214 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTN 552
            K+VGILA+++YFP   V Q  LE  +    GKYT+GLGQ  M FCS  ED+ S+ LT V  L+E+ K+    +GRLEVG+ET+IDKSK++KT LM++F+  GNTDIEG+D+TN
Sbjct:   52 KDVGILALEVYFPAQYVDQTDLEKFNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERTKLPWDAVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTN 164          

HSP 2 Score: 43.8986 bits (102), Expect = 1.962e-36
Identity = 34/96 (35.42%), Postives = 49/96 (51.04%), Query Frame = 2

Query:  554 ACYGGTAALFNWVNWGEK*FL-GRALWGPCGDRTGRFMQKDRKTPWEEPLLVVMLKRAWSPPLLLKRKFKGGIYVPRAFNFLKPK-----PLVGGK 823
            ACYGGTA+LFN  NW E  +  GR     CGD         R T     + +++  +A   PL+L++  + G ++  A++F KP      PLV GK
Sbjct:  165 ACYGGTASLFNAANWMESSYWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLIGPKA---PLVLEQGLR-GTHMENAYDFYKPNLASEYPLVDGK 256          

BLAST of EY744653 vs. ExPASy Swiss-Prot
Match: HMCSA_DICDI (Hydroxymethylglutaryl-CoA synthase A OS=Dictyostelium discoideum GN=hgsA PE=1 SV=2)

HSP 1 Score: 152.91 bits (385), Expect = 2.151e-36
Identity = 86/184 (46.74%), Postives = 115/184 (62.50%), Query Frame = 1

Query:  214 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNGLLRRNCCI-I*LGELG*KVVPGKGAMGSLWGPNGAVYAKGPQDPLGGAPAGGHVKKGLEPPVAFEKKI*G 762
            +N+GI  +++YFP T V QE LE  DG S+GKYT+GLGQ  MAFC + ED+ S+SL AV NL++K+ +DP  IGRLEVG+ETVIDKSKS+KT LM +F K GNT I+G+D+ N        +   L  +      G+ A+  +   + AVY KGP  P GGA     +  G   P+ FE  + G
Sbjct:    5 ENIGIHGIEVYFPSTYVAQEDLEKFDGVSQGKYTLGLGQTNMAFCGDREDIYSLSLNAVNNLMDKFNVDPNSIGRLEVGTETVIDKSKSVKTVLMDLFAKHGNTSIDGIDTINACYGGTSALHNALQWMESSYWDGRNAI--VVAGDIAVYEKGPARPTGGAGVVA-MLIGPNAPITFESGLRG 185          

BLAST of EY744653 vs. ExPASy Swiss-Prot
Match: HMCS1_CHICK (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Gallus gallus GN=HMGCS1 PE=1 SV=1)

HSP 1 Score: 144.05 bits (362), Expect = 9.991e-34
Identity = 84/187 (44.92%), Postives = 116/187 (62.03%), Query Frame = 1

Query:  214 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNGLLRRNCCII-*LGELG*KVVPGKGAMGSLWGPNGAVYAKGPQDPLGGAPAGGHVKKGLEPPVAFEKKI*GGNL 771
            K+VGI+A++IYFP   V Q  LE +DG   GKYTIGLGQ  M FCS+ ED+ S+ LT V  L+E+  +    IGRLEVG+ET+IDKSKS+KT LMQ+FE+ GNTD+EG+D+TN        +   +  +      G+ A+  +   + AVYA G   P GGA A   +  G   P+ FE+ + G ++
Sbjct:   15 KDVGIVALEIYFPSQYVDQTELEKYDGVDAGKYTIGLGQSKMGFCSDREDINSLCLTVVQKLMERNSLSYDCIGRLEVGTETIIDKSKSVKTVLMQLFEESGNTDVEGIDTTNACYGGTAALFNAINWIESSSWDGRYAL--VVAGDIAVYATGNARPTGGAGAVA-MLVGSNAPLIFERGLRGTHM 198          

BLAST of EY744653 vs. ExPASy Swiss-Prot
Match: HMCS1_PONAB (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Pongo abelii GN=HMGCS1 PE=2 SV=1)

HSP 1 Score: 141.739 bits (356), Expect = 4.959e-33
Identity = 83/187 (44.39%), Postives = 117/187 (62.57%), Query Frame = 1

Query:  214 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNGLLRRNCCII-*LGELG*KVVPGKGAMGSLWGPNGAVYAKGPQDPLGGAPAGGHVKKGLEPPVAFEKKI*GGNL 771
            K+VGI+A++IYFP   V Q  LE +DG + GKYTIGLGQ  M FC++ ED+ S+ +T V NL+E+  +    IGRLEVG+ET+IDKSKS+KT LMQ+FE+ GNTDIEG+D+TN        +   +  +      G+ A+  +   + AVYA G   P GG  A   +  G   P+ FE+ + G ++
Sbjct:   15 KDVGIVALEIYFPSQYVDQAELEKYDGVAAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYAL--VVAGDIAVYATGNARPTGGVGAVA-LLIGPNAPLIFERGLRGTHM 198          

BLAST of EY744653 vs. ExPASy Swiss-Prot
Match: HMCS1_HUMAN (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Homo sapiens GN=HMGCS1 PE=1 SV=2)

HSP 1 Score: 141.354 bits (355), Expect = 6.476e-33
Identity = 83/187 (44.39%), Postives = 116/187 (62.03%), Query Frame = 1

Query:  214 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNGLLRRNCCII-*LGELG*KVVPGKGAMGSLWGPNGAVYAKGPQDPLGGAPAGGHVKKGLEPPVAFEKKI*GGNL 771
            K+VGI+A++IYFP   V Q  LE +DG   GKYTIGLGQ  M FC++ ED+ S+ +T V NL+E+  +    IGRLEVG+ET+IDKSKS+KT LMQ+FE+ GNTDIEG+D+TN        +   +  +      G+ A+  +   + AVYA G   P GG  A   +  G   P+ FE+ + G ++
Sbjct:   15 KDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYAL--VVAGDIAVYATGNARPTGGVGAVA-LLIGPNAPLIFERGLRGTHM 198          

BLAST of EY744653 vs. ExPASy Swiss-Prot
Match: HMCS2_BLAGE (Hydroxymethylglutaryl-CoA synthase 2 OS=Blattella germanica GN=HMGCS-2 PE=2 SV=1)

HSP 1 Score: 125.946 bits (315), Expect = 2.488e-32
Identity = 60/117 (51.28%), Postives = 84/117 (71.79%), Query Frame = 1

Query:  214 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNGLLR 564
            ++VGI+ +++ FP   V Q  LE +D  S GKYT+GLGQ+ M  C++ ED+ S+ LTAV  L+E+  ID   IG LEVG+ET++DK KS+KT LMQ+FE+ GNTD+EG+D+ N   R
Sbjct:    6 EDVGIIGIEMIFPSLYVDQAELETYDEVSPGKYTMGLGQDKMGVCTDREDINSLCLTAVDKLMERNNIDYNDIGWLEVGTETILDKVKSVKTVLMQLFEESGNTDVEGIDTINACYR 122          

HSP 2 Score: 27.7202 bits (60), Expect = 2.488e-32
Identity = 12/17 (70.59%), Postives = 13/17 (76.47%), Query Frame = 2

Query:  554 ACYGGTAALFNWVNWGE 604
            ACY GTAALFN + W E
Sbjct:  119 ACYRGTAALFNALIWIE 135          

HSP 3 Score: 27.335 bits (59), Expect = 2.488e-32
Identity = 9/19 (47.37%), Postives = 15/19 (78.95%), Query Frame = 3

Query:  594 IGVKSSSWEGRYGVLVGTE 650
            I ++SSSW+GRY ++V  +
Sbjct:  132 IWIESSSWDGRYAIVVAAD 150          

BLAST of EY744653 vs. ExPASy Swiss-Prot
Match: HMCS1_CRIGR (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Cricetulus griseus GN=HMGCS1 PE=3 SV=1)

HSP 1 Score: 139.043 bits (349), Expect = 3.214e-32
Identity = 81/187 (43.32%), Postives = 116/187 (62.03%), Query Frame = 1

Query:  214 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNGLLRRNCCII-*LGELG*KVVPGKGAMGSLWGPNGAVYAKGPQDPLGGAPAGGHVKKGLEPPVAFEKKI*GGNL 771
            K+VGI+A++IYFP   V Q  LE +DG   GKYTIGLGQ  M FC++ ED+ S+ LT V NL+E+  +    IGRLEVG+ET+IDKSKS+K+ LMQ+FE+ GNTDIEG+D+TN        +   +  +      G+ A+  +   + A+YA G   P GG  A   +  G   P+ F++ + G ++
Sbjct:   15 KDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCTDREDINSLCLTVVQNLMERNSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYAL--VVAGDIAIYATGNARPTGGVGAVA-LLIGPNAPLIFDRGLRGTHM 198          

BLAST of EY744653 vs. ExPASy Swiss-Prot
Match: HMCS1_RAT (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Rattus norvegicus GN=Hmgcs1 PE=1 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 5.483e-32
Identity = 81/187 (43.32%), Postives = 115/187 (61.50%), Query Frame = 1

Query:  214 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNGLLRRNCCII-*LGELG*KVVPGKGAMGSLWGPNGAVYAKGPQDPLGGAPAGGHVKKGLEPPVAFEKKI*GGNL 771
            K+VGI+A++IYFP   V Q  LE +DG   GKYTIGLGQ  M FC++ ED+ S+ LT V  L+E+  +    IGRLEVG+ET+IDKSKS+K+ LMQ+FE+ GNTDIEG+D+TN        +   +  +      G+ A+  +   + A+YA G   P GG  A   +  G   PV F++ + G ++
Sbjct:   15 KDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCTDREDINSLCLTVVQKLMERNSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYAL--VVAGDIAIYASGNARPTGGVGAVA-LLIGPNAPVIFDRGLRGTHM 198