DY305587

BLAST of DY305587 vs. ExPASy Swiss-Prot
Match: LDHD_MOUSE (Probable D-lactate dehydrogenase, mitochondrial OS=Mus musculus GN=Ldhd PE=1 SV=1)

HSP 1 Score: 256.914 bits (655), Expect = 1.111e-69
Identity = 136/299 (45.48%), Postives = 190/299 (63.55%), Query Frame = 3

Query:    9 VKALHIEDMDVVVEPGIGWMELNEYLEPYGLFFPLDPGPGATIGGMCATRCSGSLAVRYGTMRDNVINLKVVLANGDVVKTASRAR---KSAAGYDLTRLIIGSEGTLGIITEVTLRLQKIPQHSVVATCNFPTIKDAADVAIATMLSGIQVSRVELLDEVQVRAVNIANGKNLPELPTLMFEFIGTQAYSHEQTLIVQKIVSEHNGTDFIFAEDPEAKKELWKMRKEALWACFAMEPSFEAMISDVCVPLSCLAELISRSKKELDASPLICTVIAHARDGNFSHGELFDPNQKKERRK 896
            +  L+ ED  VVVEPG+    LN +L   GL+FP+DPG  A++ GM AT  SG+ AVRYGTMRDNVINL+VVL +G ++ TA R R   KSAAGY+LT L +GSEGTLGIIT  TLRL   P+ +V ATC FP+++ A D  +  + + + V+R+E LD+V + A N  +  N P  PTL  EF G+Q    EQ    + I  ++ G+ F +A++ E + ELW  R  A +A  A+ P  +A  +DVCVP+S L E++  +K+E+ AS L   ++ H  DGNF    L DP+  +E+R+
Sbjct:  122 ITELNTEDFSVVVEPGVTRKALNTHLRDSGLWFPVDPGADASLCGMAATGASGTNAVRYGTMRDNVINLEVVLPDGRLLHTAGRGRHYRKSAAGYNLTGLFVGSEGTLGIITSTTLRLHPAPEATVAATCAFPSVQAAVDSTVQILQAAVPVARIEFLDDVMMDACNRHSKLNCPVAPTLFLEFHGSQQTLAEQLQRTEAITQDNGGSHFSWAKEAEKRNELWAARHNAWYAALALSPGSKAYSTDVCVPISRLPEILVETKEEIKASKLTGAIVGHVGDGNFHCILLVDPDDAEEQRR 420          

HSP 2 Score: 26.9498 bits (58), Expect = 1.111e-69
Identity = 15/36 (41.67%), Postives = 17/36 (47.22%), Query Frame = 1

Query:  892 ENRTVKS---NHGPNCPCHGRNCNCEHGFGTGKRNI 990
            E R VK+   N G      G  C  EHG G GKR +
Sbjct:  417 EQRRVKAFAENLGRRALALGGTCTGEHGIGLGKRQL 452          

BLAST of DY305587 vs. ExPASy Swiss-Prot
Match: DLD1_KLULA (D-lactate dehydrogenase [cytochrome], mitochondrial OS=Kluyveromyces lactis GN=DLD1 PE=3 SV=2)

HSP 1 Score: 244.973 bits (624), Expect = 1.006e-64
Identity = 131/297 (44.11%), Postives = 188/297 (63.30%), Query Frame = 3

Query:   18 LHIEDMDVVVEPGIGWMELNEYLEPYGLFFPLDPGPGATIGGMCATRCSGSLAVRYGTMRDNVINLKVVLANGDVVKTASRARKSAAGYDLTRLIIGSEGTLGIITEVTLRLQKIPQHSVVATCNFPTIKDAADVAIATMLSGIQVSRVELLDEVQVRAVN---IANGKNLPELPTLMFEFIG-TQAYSHEQTLIVQKIVSEHNGTDFIFAEDPEAKKELWKMRKEALWACF----AMEPSFEAMISDVCVPLSCLAELISRSKKELDASPLICTVIAHARDGNFSHGELFDPNQKK 884
            L+ ED+DVVV+ G+ W ELNEYL  +GL F  DPGPGA I G  A  CSG+ A RYGTM++NV+N+ + +A+G +VKT  R RKS+AGY+L  LIIGSEGTLGI+TE T++         VA   FPT+ DAA  +   + +GIQ++ +ELLD+  ++ +N     +  N  E PTL F+  G ++    E    V+KI S+HN T F FA D ++K ELW+ RK ALW+         P      +DV VP+S  A++I+ +K+E++AS L+ +++ HA DGNF    +++  Q+K
Sbjct:  206 LNKEDLDVVVQGGVPWEELNEYLNDHGLLFGCDPGPGAQIAGCIANSCSGTNAYRYGTMKENVVNITMCMADGTIVKTKRRPRKSSAGYNLNGLIIGSEGTLGIVTEATIKCHVRSTFETVAVVPFPTVSDAASCSSHLIQAGIQLNAMELLDDNMMKIINQSGATSKDNWVESPTLFFKIGGRSEQIIQEVIKEVEKIASQHNNTKFEFATDEDSKLELWEARKVALWSTIDTGRKTNPDANIWTTDVAVPISKFADVINATKEEMNASGLLTSLVGHAGDGNFHAFIIYNTEQRK 502          

HSP 2 Score: 22.3274 bits (46), Expect = 1.006e-64
Identity = 8/13 (61.54%), Postives = 9/13 (69.23%), Query Frame = 1

Query:  949 CNCEHGFGTGKRN 987
            C  EHG G GKR+
Sbjct:  522 CTGEHGVGIGKRD 534          

BLAST of DY305587 vs. ExPASy Swiss-Prot
Match: LDHD_HUMAN (Probable D-lactate dehydrogenase, mitochondrial OS=Homo sapiens GN=LDHD PE=1 SV=1)

HSP 1 Score: 236.884 bits (603), Expect = 9.173e-63
Identity = 131/316 (41.46%), Postives = 187/316 (59.18%), Query Frame = 3

Query:   18 LHIEDMDVVVEPGIGWMELNEYLEPYGLFFPLDPGPGATIGGMCATRCSGSLAVRYGTMRDNVINLKVVLANGDVVKTASRAR--------------------------KSAAGYDLTRLIIGSEGTLGIITEVTLRLQKIPQHSVVATCNFPTIKDAADVAIATMLSGIQVSRVELLDEVQVRAVNIANGKNLPELPTLMFEFIGTQAYSHEQTLIVQKIVSEHNGTDFIFAEDPEAKKELWKMRKEALWACFAMEPSFEAMISDVCVPLSCLAELISRSKKELDASPLICTVIAHARDGNFSHGELFDPNQKKE 887
            L+ ED  VVVEPG+    LN +L   GL+FP+DPG  A++ GM AT  SG+ AVRYGTMRDNV+NL+VVL +G ++ TA R R                          KSAAGY+LT L +GSEGTLG+IT  TLRL   P+ +V ATC FP+++ A D  +  + + + V+R+E LDEV + A N  +  N    PTL  EF G+Q    EQ    ++IV ++  +DF +A++ E +  LW  R  A +A  A  P  +   +DVCVP+S L E++ ++K++L+AS L  +++ H  DGNF    L +P+  +E
Sbjct:  125 LNQEDFSVVVEPGVTRKALNAHLRDSGLWFPVDPGADASLCGMAATGASGTNAVRYGTMRDNVLNLEVVLPDGRLLHTAGRGRHFRFGFWPEIPHHTAWYSPCVSLGRRKSAAGYNLTGLFVGSEGTLGLITATTLRLHPAPEATVAATCAFPSVQAAVDSTVHILQAAVPVARIEFLDEVMMDACNRYSKLNCLVAPTLFLEFHGSQQALEEQLQRTEEIVQQNGASDFSWAKEAEERSRLWTARHNAWYAALATRPGCKGYSTDVCVPISRLPEIVVQTKEDLNASGLTGSIVGHVGDGNFHCILLVNPDDAEE 440          

HSP 2 Score: 23.8682 bits (50), Expect = 9.173e-63
Identity = 10/18 (55.56%), Postives = 11/18 (61.11%), Query Frame = 1

Query:  937 HGRNCNCEHGFGTGKRNI 990
            HG  C  EHG G GKR +
Sbjct:  459 HG-TCTGEHGIGMGKRQL 475          

BLAST of DY305587 vs. ExPASy Swiss-Prot
Match: DLD1_YEAST (D-lactate dehydrogenase [cytochrome] 1, mitochondrial OS=Saccharomyces cerevisiae GN=DLD1 PE=1 SV=2)

HSP 1 Score: 222.246 bits (565), Expect = 8.251e-58
Identity = 120/282 (42.55%), Postives = 177/282 (62.77%), Query Frame = 3

Query:   30 DMDVVVEPGIGWMELNEYLEPYGLFFPLDPGPGATIGGMCATRCSGSLAVRYGTMRDNVINLKVVLANGDVVKTASRARKSAAGYDLTRLIIGSEGTLGIITEVTLRLQKIPQHSVVATCNFPTIKDAADVAIATMLSGIQVSRVELLDEVQVRAVNIANGK---NLPELPTLMFEFIGTQAYSHEQTLI--VQKIVSEHNGTDFIFAEDPEAKKELWKMRKEALWACF----AMEPSFEAMISDVCVPLSCLAELISRSKKELDASPLICTVIAHARDGNF 848
            D+D+ V+ G+ W +LN+YL  +GL F  DPGPGA IGG  A  CSG+ A RYGTM++N+IN+ +VL +G +VKT  R RKS+AGY+L  L +GSEGTLGI+TE T++    P+   VA  +F TIKDAA  A     SGI ++ +ELLDE  ++ +N +      +  E PT+ F+ IG ++ +    L+  V+ +   ++   F FA+D + K ELW+ RK ALW+      + + S +   +DV VP+S   ++I  +KK++ AS LI  ++ HA DGNF
Sbjct:  217 DLDITVQAGLPWEDLNDYLSDHGLMFGCDPGPGAQIGGCIANSCSGTNAYRYGTMKENIINMTIVLPDGTIVKTKKRPRKSSAGYNLNGLFVGSEGTLGIVTEATVKCHVKPKAETVAVVSFDTIKDAAACASNLTQSGIHLNAMELLDENMMKLINASESTDRCDWVEKPTMFFK-IGGRSPNIVNALVDEVKAVAQLNHCNSFQFAKDDDEKLELWEARKVALWSVLDADKSKDKSAKIWTTDVAVPVSQFDKVIHETKKDMQASKLINAIVGHAGDGNF 497          

HSP 2 Score: 21.9422 bits (45), Expect = 8.251e-58
Identity = 8/12 (66.67%), Postives = 8/12 (66.67%), Query Frame = 1

Query:  949 CNCEHGFGTGKR 984
            C  EHG G GKR
Sbjct:  530 CTGEHGVGIGKR 541          

BLAST of DY305587 vs. ExPASy Swiss-Prot
Match: GLCD_BACSU (Glycolate oxidase subunit glcD OS=Bacillus subtilis GN=glcD PE=3 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 9.067e-27
Identity = 86/294 (29.25%), Postives = 134/294 (45.58%), Query Frame = 3

Query:   27 EDMDVVVEPGIGWMELNEYLEPYGLFFPLDPGPG--ATIGGMCATRCSGSLAVRYGTMRDNVINLKVVLANGDVVKTASRARKSAAGYDLTRLIIGSEGTLGIITEVTLRLQKIPQHSVVATCNFPTIKDAADVAIATMLSGIQVSRVELLDEVQVRAVNIANGKNLP--ELPTLMFEFIGTQAYSHEQTLIVQKIVSEHNGTDFIFAEDPEAKKELWKMRKEALWACFAMEPSFEAMISDVCVPLSCLAELISRSKKELDASPLICTVIAHARDGNFSHGELFDPNQKKERRK 896
            E++   V+PG+  +++   +E  GLF+P DP     +TIGG       G   ++YG  RD VI L+VVLANGD+++T  +  K  AGYDLTRL +GSEGTLGI+TE  ++L   P+        +  I  AA      + + I  + +E LD+  +  +       LP      L+ E  G           ++ I  + +      A+  E    L + R+ AL A   ++P+   ++ D  VP S +A ++           +      HA DGN       D   K E  +
Sbjct:  103 ENLTATVQPGVITLDMIRAVESKGLFYPPDPSSMKISTIGGNINENSGGLRGLKYGVTRDYVIGLEVVLANGDIIRTGGKLAKDVAGYDLTRLFVGSEGTLGIVTEAIVKLVPKPETKKTLLALYENIDAAAQTVSDIIAAKIIPATLEFLDQPTLLVIEDYAKIGLPTSAKAVLLIEQDGPFETVERDMEKIEAICKKGDAVSVQTAQTEEEAFALTEARRSALSALARLKPT--TILEDATVPRSEIANMVKAINDIAAKYDISICTFGHAGDGNLHPTCTTDIRNKDEMER 394          

BLAST of DY305587 vs. ExPASy Swiss-Prot
Match: GLCD_ECOLI (Glycolate oxidase subunit glcD OS=Escherichia coli (strain K12) GN=glcD PE=3 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 1.956e-21
Identity = 78/285 (27.37%), Postives = 130/285 (45.61%), Query Frame = 3

Query:   45 VEPGIGWMELNEYLEPYGLFFPLDPGP--GATIGGMCATRCSGSLAVRYGTMRDNVINLKVVLANGDVVKTASRARKSAAGYDLTRLIIGSEGTLGIITEVTLRLQKIPQHSVVATCNFPTIKDAADVAIATMLSGIQVSRVELLDEVQVRAVN--IANGKNLPELPTLMFEFIGTQAYSHEQTLIVQKIVSEHNGTDFIFAEDPEAKKELWKMRKEALWACFAMEPSFEAMISDVCVPLSCLAELISRSKKELDASPLICTVIAHARDGNFSHGELFDPNQKKE 887
            V+PG+  + +++ + P+ L++  DP      +IGG  A    G   ++YG    N++ ++V   +G+ +   S A  S  G+DL  L  GSEG LG+ TEVT++L   P  + V   +F +++ A       + +GI    +E++D + +RA    I  G  +     L+ E  G ++   E    V  I+ +   TD   A+D   +   W  RK A  A   + P +  M  D  +P   L  ++    +      L    + HA DGN     LFD N+  E
Sbjct:  124 VQPGVRNLAISQAVAPHNLYYAPDPSSQIACSIGGNVAENAGGVHCLKYGLTVHNLLKIEVQTLDGEALTLGSDALDSP-GFDLLALFTGSEGMLGVTTEVTVKLLPKPPVARVLLASFDSVEKAGLAVGDIIANGIIPGGLEMMDNLSIRAAEDFIHAGYPVDAEAILLCELDGVESDVQEDCERVNDILLKAGATDVRLAQDEAERVRFWAGRKNAFPAVGRISPDYYCM--DGTIPRRALPGVLEGIARLSQQYDLRVANVFHAGDGNMHPLILFDANEPGE 405          

BLAST of DY305587 vs. ExPASy Swiss-Prot
Match: GLCD_ECOL6 (Glycolate oxidase subunit glcD OS=Escherichia coli O6 GN=glcD PE=3 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 1.956e-21
Identity = 78/285 (27.37%), Postives = 130/285 (45.61%), Query Frame = 3

Query:   45 VEPGIGWMELNEYLEPYGLFFPLDPGP--GATIGGMCATRCSGSLAVRYGTMRDNVINLKVVLANGDVVKTASRARKSAAGYDLTRLIIGSEGTLGIITEVTLRLQKIPQHSVVATCNFPTIKDAADVAIATMLSGIQVSRVELLDEVQVRAVN--IANGKNLPELPTLMFEFIGTQAYSHEQTLIVQKIVSEHNGTDFIFAEDPEAKKELWKMRKEALWACFAMEPSFEAMISDVCVPLSCLAELISRSKKELDASPLICTVIAHARDGNFSHGELFDPNQKKE 887
            V+PG+  + +++ + P+ L++  DP      +IGG  A    G   ++YG    N++ ++V   +G+ +   S A  S  G+DL  L  GSEG LG+ TEVT++L   P  + V   +F +++ A       + +GI    +E++D + +RA    I  G  +     L+ E  G ++   E    V  I+ +   TD   A+D   +   W  RK A  A   + P +  M  D  +P   L  ++    +      L    + HA DGN     LFD N+  E
Sbjct:  124 VQPGVRNLAISQAVAPHNLYYAPDPSSQIACSIGGNVAENAGGVHCLKYGLTVHNLLKIEVQTLDGEALTLGSDALDSP-GFDLLALFTGSEGMLGVTTEVTVKLLPKPPVARVLLASFDSVEKAGLAVGDIIANGIIPGGLEMMDNLSIRAAEDFIHAGYPVDAEAILLCELDGVESDVQEDCERVNDILLKAGATDVRLAQDEAERVRFWAGRKNAFPAVGRISPDYYCM--DGTIPRRALPGVLEGIARLSQQYDLRVANVFHAGDGNMHPLILFDANEPGE 405          

BLAST of DY305587 vs. ExPASy Swiss-Prot
Match: D2HDH_BOVIN (D-2-hydroxyglutarate dehydrogenase, mitochondrial OS=Bos taurus GN=D2HGDH PE=2 SV=2)

HSP 1 Score: 98.2117 bits (243), Expect = 1.074e-19
Identity = 78/277 (28.16%), Postives = 121/277 (43.68%), Query Frame = 3

Query:   39 VVVEPGIGWMELNEYLEPYGLFFPLDPGPGAT--IGGMCATRCSGSLAVRYGTMRDNVINLKVVLANGDVVKTASRARKSAAGYDLTRLIIGSEGTLGIITEVTLRLQKIPQHSVVATCNFPTIKDAADV-AIATMLSGIQVSRVELLDEVQVRAVNIANGKNLPELPTLMFEFIGTQAY-----SHEQTLIVQKIVSEHNGTDFIFAEDPEAKKELWKMRKEALWACFAMEPSFEAMISDVCVPLSCLAELISRSKKELDASPLICTVIAHARDGN 845
            +V + G     L++Y+E  G   PLD G   +  IGG  AT   G   +RYG++R  V+ L+VVLA+G V+   +  RK   GYDL +L IGSEGTLG+IT V++     P    VA    P   +          + G  +S  E +D   ++ V +  G + P   +  +  I T        + +    +++++     TD     D    K LW +R+       A+         D+ +PL  L +L+   +  L  S        H  DGN
Sbjct:  189 LVCQAGCVLEALSQYVEERGFIMPLDLGAKGSCHIGGNVATNAGGLRVLRYGSLRGTVLGLEVVLADGTVLNCLTSLRKDNTGYDLKQLFIGSEGTLGVITAVSILCPPKPSTVNVAFLGCPGFAEVLQTFRTCRAMLGEILSAFEFMDAECMKLVRLHLGLSCPVQESPFYVLIETAGSGPGHDAEKLGCFLEQVLDSGLVTDGTLGSDERRIKMLWALRER---ITEALSRDGYVYKYDLSLPLDRLYDLVGDLRARLGPSAKHVVGYGHLGDGN 462          

BLAST of DY305587 vs. ExPASy Swiss-Prot
Match: YN53_SCHPO (Putative D-lactate dehydrogenase C713.03, mitochondrial OS=Schizosaccharomyces pombe GN=SPBC713.03 PE=2 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 1.402e-19
Identity = 78/288 (27.08%), Postives = 134/288 (46.53%), Query Frame = 3

Query:   39 VVVEPGIGWMELNEYLEPYGLFFPLDPGPGAT--IGGMCATRCSGSLAVRYGTMRDNVINLKVVLANGDVVKTASRARKSAAGYDLTRLIIGSEGTLGIITEVTLRLQKIPQHSVVATCNFPTIKDAADVAIATMLSGIQV-SRVELLDEVQVRAVNIANGKNLP-ELPTLMFEFIGTQAYSHEQ-----TLIVQKIVSEHNGTDFIFAEDPEAKKELWKMRKEALWACFAMEPSFEAMISDVCVPLSCLAELISRSKKEL---------DASPLICTV-IAHARDGN 845
            + ++ G+     + +L   G  FPLD G   +  +GG  AT   G   +RYG++  +++ ++ VL +G ++      RK   G D+ +L IGSEG LG+IT++++   K P  + VA    P+ ++       T     ++ S  EL+D      V+  +G   P E     +  + TQ  + E      T +V+ ++ +   +D + A+D    + LW+ R+E +  C A   S      DV +PL  L +L++ +KK L            P+I  V   H  DGN
Sbjct:  163 ITLDSGVILENADNFLAEKGYMFPLDLGAKGSCQVGGCAATAAGGLRLLRYGSLHGSILGMEAVLPDGTILDNLVTLRKDNTGLDIKQLFIGSEGYLGVITKLSVICPKRPSSTNVAFFGVPSYENVLKAFSETRSHLTEILSAFELMDNTSQTLVDKYSGTQRPLEDEHPFYVLVETQGSNKEHDEQKITALVEDLLEKEIISDGVLAQDESQLRVLWE-RREGITECLAKAGS-GVYKYDVSLPLPVLYDLVNDTKKRLIEFNLLDDTPEHPVIDVVGFGHMGDGN 448          

BLAST of DY305587 vs. ExPASy Swiss-Prot
Match: DLD2_YEAST (D-lactate dehydrogenase [cytochrome] 2, mitochondrial OS=Saccharomyces cerevisiae GN=DLD2 PE=1 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 2.025e-18
Identity = 83/279 (29.75%), Postives = 131/279 (46.95%), Query Frame = 3

Query:   24 IEDMDVV-----VEPGIGWMELNEYLEPYGLFFPLDPGPGAT--IGGMCATRCSGSLAVRYGTMRDNVINLKVVLANGDVVKTASRARKSAAGYDLTRLIIGSEGTLGIITEVTLRLQKIPQHSVVATCNFPTIKDAADVAIATM--LSGIQVSRVELLD-EVQVRAVNIANGKNLP---ELP-TLMFEFIGTQAYSHEQTL--IVQKIVSEHNGTDFIFAEDPEAKKELWKMRKEALWACFAMEPSFEAMISDVCVPLSCLAELISRSKKELDASPLI 812
            I D D V      + G+     N Y+      FPLD G   +  +GG+ AT   G   +RYG++  +V+ L+VV+ NG +V +    RK   GYDL +L IGSEGT+GIIT V++     P+   V+  +  + +D   V +     LS I +S  E +D + QV A +       P   E P  ++ E  G+     +  L   ++ ++ E   TD + A+D    + LWK R+    A  A    ++    DV +PL  L  L+  +   L  + L+
Sbjct:  158 IRDFDPVSGILKCDAGVILENANNYVMEQNYMFPLDLGAKGSCHVGGVVATNAGGLRLLRYGSLHGSVLGLEVVMPNGQIVNSMHSMRKDNTGYDLKQLFIGSEGTIGIITGVSILTVPKPKAFNVSYLSVESFEDVQKVFVRARQELSEI-LSAFEFMDAKSQVLAKSQLKDAAFPLEDEHPFYILIETSGSNKDHDDSKLETFLENVMEEGIVTDGVVAQDETELQNLWKWREMIPEASQANGGVYK---YDVSLPLKDLYSLVEATNARLSEAELV 432