DR908534

BLAST of DR908534 vs. ExPASy Swiss-Prot
Match: FAB1_YEAST (1-phosphatidylinositol-3-phosphate 5-kinase FAB1 OS=Saccharomyces cerevisiae GN=FAB1 PE=1 SV=1)

HSP 1 Score: 144.821 bits (364), Expect = 1.227e-40
Identity = 72/169 (42.60%), Postives = 108/169 (63.91%), Query Frame = 2

Query:    8 GKVKFSVTSYFAKQFDSLRKKCCPSGVDFVRSLSRSRKWSAQGGKSNVFFAKSLDERFIIKQVKKTELESFEEFAPEYFKYLTDSLNSRSPTCLAKILGIYQVSVK-HLKGGKETKIDLMVMENLFFRRSISRVYDLKGSARSRYNTDTTGTNKVLLDMNLLKIYVQNP 511
            G    S   +F + FD  RK  C    +F++SLSR  KW + GGKS   F K+LD+RFIIK++   ELE+F +FAP YF+Y+  ++    PT LAK+ G YQ+ VK  +   K  K+D+++MENLF+ +  +R++DLKGS R+R+   T   N+VLLD N+++   ++P
Sbjct: 2000 GLTVMSCKIFFTEHFDVFRK-ICDCQENFIQSLSRCVKWDSNGGKSGSGFLKTLDDRFIIKELSHAELEAFIKFAPSYFEYMAQAMFHDLPTTLAKVFGFYQIQVKSSISSSKSYKMDVIIMENLFYEKKTTRIFDLKGSMRNRHVEQTGKANEVLLDENMVEYIYESP 2167          

HSP 2 Score: 42.743 bits (99), Expect = 1.227e-40
Identity = 20/44 (45.45%), Postives = 32/44 (72.73%), Query Frame = 3

Query:  492 KFTYRTLISWKQA*RSLKRA-IWNDTSFLASVDVMDYSLLVGMD 620
            ++ Y + I  ++  + L RA +WNDT FLA ++VMDYSL++G+D
Sbjct: 2161 EYIYESPIHVREYDKKLLRASVWNDTLFLAKMNVMDYSLVIGID 2204          

BLAST of DR908534 vs. ExPASy Swiss-Prot
Match: FYV1_HUMAN (1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=2)

HSP 1 Score: 153.295 bits (386), Expect = 1.731e-39
Identity = 78/174 (44.83%), Postives = 114/174 (65.52%), Query Frame = 2

Query:   17 KFSVTSYFAKQFDSLRKKCCPSGV-DFVRSLSRSRKWSAQGGKSNVFFAKSLDERFIIKQVKKTELESFEEFAPEYFKYLTDSLNSRSPTCLAKILGIYQVSVKHLKGGKETKIDLMVMENLFFRRSISRVYDLKGSARSRYNTDTTGTNK---VLLDMNLLKIYVQNPYFLEA 526
            KF    Y+A +F  +R+    S   DF+RSLS S  W A+GGKS   F  + D+RFI+KQ+ + E++SF +FAP YF Y+T+++  + PT LAKILG+Y++  K+ +   E K+DL+VMENLF+ R +++V+DLKGS R+R     TG      VLLD NLLK+   NP ++ +
Sbjct: 1819 KFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRS 1992          

HSP 2 Score: 30.4166 bits (67), Expect = 1.731e-39
Identity = 14/27 (51.85%), Postives = 21/27 (77.78%), Query Frame = 3

Query:  540 LKRAIWNDTSFLASVDVMDYSLLVGMD 620
            L+ +I +D+ FL+S  ++DYSLLVG D
Sbjct: 1998 LRTSIHSDSHFLSSHLIIDYSLLVGRD 2024          

BLAST of DR908534 vs. ExPASy Swiss-Prot
Match: FYV1_DICDI (1-phosphatidylinositol-3-phosphate 5-kinase OS=Dictyostelium discoideum GN=pip5k3 PE=3 SV=1)

HSP 1 Score: 139.813 bits (351), Expect = 4.975e-39
Identity = 79/172 (45.93%), Postives = 111/172 (64.53%), Query Frame = 2

Query:    5 GGKVKFSVTSYFAKQFDSLRKKCCPSGVDFVRSLSRSRKWSAQGGKSNVFFAKSLDERFIIKQVKKTELESFEEFAPEYFKYLTDSLNSRSPTCLAKILGIYQVSVKHLKGGKETKIDLMVMENLFFRRSISRVYDLKGSARSRYNTDTTGTNKVLLDMNLLKIYVQNPYFL 520
            G ++    +SY+  QF +LR+  C    +F++SL+RS+ W+A+GGKS   + K+LD+RFI+KQV + ELESF +FAP YF+Y+  S  ++ PT L KILG++ V  K    GK  K DL+VMENLF  + IS+ YDLKGS R R        ++VLLD NLL+    +P  L
Sbjct: 2336 GYELNIFCSSYYPVQFHALREYMC-GDQEFIQSLTRSKIWNAKGGKSGSSWNKTLDDRFILKQVSRIELESFLDFAPLYFEYICKSFLNQIPTALCKILGVFTVRWKD-SNGKALKKDLIVMENLFHSKCISKTYDLKGSLRGRL---VKNESEVLLDENLLQASFASPICL 2502          

HSP 2 Score: 42.3578 bits (98), Expect = 4.975e-39
Identity = 17/24 (70.83%), Postives = 23/24 (95.83%), Query Frame = 3

Query:  549 AIWNDTSFLASVDVMDYSLLVGMD 620
            A+WNDT+FL+S++VMDYSLL G+D
Sbjct: 2513 AVWNDTAFLSSLNVMDYSLLSGID 2536          

BLAST of DR908534 vs. ExPASy Swiss-Prot
Match: FYV1_MOUSE (1-phosphatidylinositol-3-phosphate 5-kinase OS=Mus musculus GN=Pikfyve PE=1 SV=2)

HSP 1 Score: 151.369 bits (381), Expect = 8.463e-39
Identity = 77/174 (44.25%), Postives = 114/174 (65.52%), Query Frame = 2

Query:   17 KFSVTSYFAKQFDSLRKKCCPSGVD-FVRSLSRSRKWSAQGGKSNVFFAKSLDERFIIKQVKKTELESFEEFAPEYFKYLTDSLNSRSPTCLAKILGIYQVSVKHLKGGKETKIDLMVMENLFFRRSISRVYDLKGSARSRYNTDTTGTNK---VLLDMNLLKIYVQNPYFLEA 526
            KF    Y+A +F  +R+    S  + F+RSLS S  W A+GGKS   F  + D+RFI+KQ+ + E++SF +FAP YF Y+T+++  + PT LAKILG+Y++  K+ +   E K+DL+VMENLF+ R +++V+DLKGS R+R     TG      VLLD NLLK+   NP ++ +
Sbjct: 1818 KFYCRLYYAGEFHKMREVILGSSEEEFIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRS 1991          

HSP 2 Score: 30.0314 bits (66), Expect = 8.463e-39
Identity = 14/27 (51.85%), Postives = 20/27 (74.07%), Query Frame = 3

Query:  540 LKRAIWNDTSFLASVDVMDYSLLVGMD 620
            L+ +I +D  FL+S  ++DYSLLVG D
Sbjct: 1997 LRTSIHSDAHFLSSHLIIDYSLLVGRD 2023          

BLAST of DR908534 vs. ExPASy Swiss-Prot
Match: FAB1_SCHPO (1-phosphatidylinositol-3-phosphate 5-kinase fab1 OS=Schizosaccharomyces pombe GN=fab1 PE=2 SV=2)

HSP 1 Score: 132.494 bits (332), Expect = 4.829e-36
Identity = 69/184 (37.50%), Postives = 108/184 (58.70%), Query Frame = 2

Query:    8 GKVKFSVTSYFAKQFDSLRKKC-CPSGVDFVRSLSRSRKWSAQGGKSNVFFAKSLDERFIIKQVKKTELESFEEFAPEYFKYLTDSLNSRSPTCLAKILGIYQVSVKHLKGGKETKIDLMVMENLFFRRSISRVYDLKGSARSRYNTDTTGTNKVLLDMNLLKIYVQNPYFLEAGIEKPKESYL 556
            G  + S   +FA+QF +LR+ C C     FV SL+R   W + GGKS   F K+ D+++I+K + + E +S   FAP YF Y++       PT L KI G Y+V +++   G   K D+M+MEN+F+    SR++DLKGS R+R+   T   ++VLLD NL+++  ++P F+   ++    S L
Sbjct: 1654 GSARLSCKVFFAEQFSALRRACGCEE--TFVTSLARCSLWESSGGKSGSAFLKTFDKKYILKVLSRLESDSLLNFAPAYFDYISKVFFHELPTALTKIFGFYRVDIRNPTTGTICKTDIMIMENVFYDECPSRIFDLKGSMRNRHVESTGKVDEVLLDENLVELIYESPIFVSEQLKSLLHSCL 1835          

HSP 2 Score: 39.6614 bits (91), Expect = 4.829e-36
Identity = 15/27 (55.56%), Postives = 22/27 (81.48%), Query Frame = 3

Query:  540 LKRAIWNDTSFLASVDVMDYSLLVGMD 620
            L   +WNDT FL+ +++MDYSL+VG+D
Sbjct: 1831 LHSCLWNDTLFLSKLNIMDYSLIVGID 1857          

BLAST of DR908534 vs. ExPASy Swiss-Prot
Match: FYV1_DROME (Putative 1-phosphatidylinositol-3-phosphate 5-kinase OS=Drosophila melanogaster GN=fab1 PE=1 SV=2)

HSP 1 Score: 110.538 bits (275), Expect = 1.134e-27
Identity = 59/146 (40.41%), Postives = 91/146 (62.33%), Query Frame = 2

Query:   86 VDFVRSLSRSRKWSAQGGKSNVFFAKSLDERFIIKQVKKTELESFEEFAPEYFKYLTDSLNSRSPTCLAKILGIYQVSVKHLKGGKETKIDLMVMENLFFRRSISRVYDLKGSARSRYNTDTTGTNK-VLLDMNLLKIYVQNPYFL 520
            +   RSL +S +W A+GGKS   F K+LD+RF++K++   ++  FE FAP+YF+Y+      + PT LAKI G+++VSVK  K     +  +MVMENLF+  +I   +DLKGS R+R    +    + VLLD NL+++    P ++
Sbjct: 1559 IALARSLCKSVQWEARGGKSGSRFCKTLDDRFVLKEMNSRDMTIFEPFAPKYFEYIDRCQQQQQPTLLAKIFGVFRVSVK--KKDSFVERSVMVMENLFYGCNIENKFDLKGSERNRLVDPSNQQGEIVLLDENLVQMSWSKPLYV 1702          

HSP 2 Score: 33.4982 bits (75), Expect = 1.134e-27
Identity = 17/27 (62.96%), Postives = 20/27 (74.07%), Query Frame = 3

Query:  540 LKRAIWNDTSFLASVDVMDYSLLVGMD 620
            L+ AI  D+SFL    VMDYSLLVG+D
Sbjct: 1710 LRDAIQRDSSFLEKNLVMDYSLLVGLD 1736          

BLAST of DR908534 vs. ExPASy Swiss-Prot
Match: PI5K7_ARATH (Phosphatidylinositol-4-phosphate 5-kinase 7 OS=Arabidopsis thaliana GN=PIP5K7 PE=1 SV=1)

HSP 1 Score: 65.4698 bits (158), Expect = 1.629e-13
Identity = 47/145 (32.41%), Postives = 76/145 (52.41%), Query Frame = 2

Query:   14 VKFSVTSYFAKQFDSLRKKCCPSGVDFVRSLSRSRKWS--AQGGKSNVFFAKSLDERFIIKQVKKTELESFEEFAPEYFKYLTDSLNSRSPTCLAKILGIYQVSVKHLKGGKETKIDLMVMENLFFRR-SISRVYDLKGSARSRY 439
            V FS   Y    F +LR+       +++ S+      +  +  GKS   F  S D+RF+IK +KK+EL+      P+Y++++ D  N    T + K  G+++++   LK GK  K+  +VM N+F     I R YDLKGS + R+
Sbjct:  387 VDFSWKDYCPMVFRNLRQMFKLDAAEYMMSICGDDGLTEISSPGKSGSIFYLSHDDRFVIKTLKKSELQVLLRMLPKYYEHVGDHEN----TLITKFFGVHRIT---LKWGK--KVRFVVMGNMFCTELKIHRRYDLKGSTQGRF 522          

HSP 2 Score: 30.8018 bits (68), Expect = 1.629e-13
Identity = 13/27 (48.15%), Postives = 22/27 (81.48%), Query Frame = 3

Query:  537 SLKRAIWNDTSFLASVDVMDYSLLVGM 617
            +L + I+ D SFL S++++DYSLL+G+
Sbjct:  552 ALFKQIYLDCSFLESLNIIDYSLLLGL 578          

BLAST of DR908534 vs. ExPASy Swiss-Prot
Match: PI5K8_ARATH (Phosphatidylinositol-4-phosphate 5-kinase 8 OS=Arabidopsis thaliana GN=PIP5K8 PE=2 SV=1)

HSP 1 Score: 66.2402 bits (160), Expect = 3.567e-13
Identity = 50/163 (30.67%), Postives = 83/163 (50.92%), Query Frame = 2

Query:   14 VKFSVTSYFAKQFDSLRKKCCPSGVDFVRSLSRS---RKWSAQGGKSNVFFAKSLDERFIIKQVKKTELESFEEFAPEYFKYLTDSLNSRSPTCLAKILGIYQVSVKHLKGGKETKIDLMVMENLFFRR-SISRVYDLKGSARSRY-NTDTTGTNKVLLDMNL 487
            + F    Y    F +LR+       D++ S+      R+ S+ G   ++F+  S D+RF+IK +K++EL+      P Y++++ D  N    T + K  G++++    LK GK  K+  +VM N+F     I R YDLKGS + RY   +  G    L D++L
Sbjct:  400 IDFDWKDYCPMVFRNLREMFKLDAADYMMSICGDDGLREISSPGKSGSIFYL-SHDDRFVIKTLKRSELKVLLRMLPRYYEHVGDYEN----TLITKFFGVHRIK---LKWGK--KVRFVVMGNMFCTELKIHRRYDLKGSTQGRYTEKNKIGEKTTLKDLDL 552          

HSP 2 Score: 28.8758 bits (63), Expect = 3.567e-13
Identity = 13/27 (48.15%), Postives = 20/27 (74.07%), Query Frame = 3

Query:  537 SLKRAIWNDTSFLASVDVMDYSLLVGM 617
            +L + I  D SFL S+ ++DYSLL+G+
Sbjct:  565 ALFKQIILDCSFLESLQILDYSLLLGL 591          

BLAST of DR908534 vs. ExPASy Swiss-Prot
Match: PI5K2_ARATH (Phosphatidylinositol-4-phosphate 5-kinase 2 OS=Arabidopsis thaliana GN=PIP5K2 PE=2 SV=2)

HSP 1 Score: 58.9214 bits (141), Expect = 2.327e-11
Identity = 43/126 (34.13%), Postives = 65/126 (51.59%), Query Frame = 2

Query:   83 GVDFVRSLSRSRKWSAQGGKSNVFFAKSLDERFIIKQVKKTELESFEEFAPEYFKYLTDSLNSRSPTCLAKILGIYQVSVKHLKGGKETKIDLMVMENLFFRR-SISRVYDLKGSARSRYNTDTTG 457
            G D +R LS         GKS  FF  + D+RF+IK VKK+E++      P Y+K++    N    T + +  G++ +      GG++T+   +VM NLF     I R +DLKGS+  RY +   G
Sbjct:  442 GNDALRELSSP-------GKSGSFFYLTQDDRFMIKTVKKSEVKVLLRMLPSYYKHVCQYEN----TLVTRFYGVHCIKP---VGGQKTR--FIVMGNLFCSEYRIQRRFDLKGSSHGRYTSKPEG 551          

HSP 2 Score: 30.0314 bits (66), Expect = 2.327e-11
Identity = 17/41 (41.46%), Postives = 22/41 (53.66%), Query Frame = 3

Query:  495 FTYRTLISWKQA*RSLKRAIWNDTSFLASVDVMDYSLLVGM 617
            F +R   +W Q    L   I  D  FL +  +MDYSLLVG+
Sbjct:  566 FAFRLQRNWYQ---ELMTQIKRDCEFLEAERIMDYSLLVGV 603          

BLAST of DR908534 vs. ExPASy Swiss-Prot
Match: PI5K6_ARATH (Phosphatidylinositol-4-phosphate 5-kinase 6 OS=Arabidopsis thaliana GN=PIP5K6 PE=2 SV=1)

HSP 1 Score: 60.077 bits (144), Expect = 2.331e-11
Identity = 48/163 (29.45%), Postives = 77/163 (47.24%), Query Frame = 2

Query:   17 KFSVTSYFAKQFDSLRKKCCPSGVDFVRSL--SRSRKWSAQGGKSNVFFAKSLDERFIIKQVKKTELESFEEFAPEYFKYLTDSLNSRSPTCLAKILGIYQVSVKHLKGGKETKIDLMVMENLFFR-RSISRVYDLKGSARSRYNT---DTTGTNKVLLDMNL 487
            +F    Y    F +LRK       D++ S+  + + +  +  GKS  FF  + D+R++IK +KK E +      P Y+ ++    N    T + K  G++ V    L G  + K+  ++M NLF    SI R +DLKGS+  R  T        N  L D++L
Sbjct:  384 EFKWKDYCPVVFRTLRKLFSVDAADYMLSICGNDALRELSSPGKSGSFFYLTNDDRYMIKTMKKAETKVLIRMLPAYYNHVRACEN----TLVTKFFGLHCVK---LTGTAQKKVRFVIMGNLFCTGHSIHRRFDLKGSSHGRLTTKPESEIDPNTTLKDLDL 539          

HSP 2 Score: 28.8758 bits (63), Expect = 2.331e-11
Identity = 16/41 (39.02%), Postives = 21/41 (51.22%), Query Frame = 3

Query:  495 FTYRTLISWKQA*RSLKRAIWNDTSFLASVDVMDYSLLVGM 617
            F +R   +W Q      R +  D  FL    +MDYSLLVG+
Sbjct:  541 FAFRLQKNWFQ---EFCRQVDRDCEFLEQERIMDYSLLVGL 578