DR908150

BLAST of DR908150 vs. ExPASy Swiss-Prot
Match: TOP1_ARATH (DNA topoisomerase 1 OS=Arabidopsis thaliana GN=TOP1 PE=1 SV=1)

HSP 1 Score: 359.377 bits (921), Expect = 1.102e-98
Identity = 183/229 (79.91%), Postives = 204/229 (89.08%), Query Frame = 2

Query:    2 LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLL 688
            +KFDFLGKDSIQYVNTVEVE  VYKAIGQFQ GK + DDLFD+LDT+KLNAHLKEL+PGLTAKVFRTYNASITLD ML++ T DGDV  KI VYQ+ANKEVAIICNHQRTVSKTH AQ+ +LT +IE+LK VLK+L+ +LDRAKKGKPPL + SDGK+ R+L P A E+K+AQ +AKIEKMERDM TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF KSLL
Sbjct:  671 IKFDFLGKDSIQYVNTVEVEPLVYKAIGQFQAGKSKTDDLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTARIEELKEVLKELKTNLDRAKKGKPPL-EGSDGKKIRSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFTKSLL 898          

BLAST of DR908150 vs. ExPASy Swiss-Prot
Match: TOP1_DAUCA (DNA topoisomerase 1 OS=Daucus carota GN=TOP1 PE=2 SV=1)

HSP 1 Score: 330.102 bits (845), Expect = 7.161e-90
Identity = 179/257 (69.65%), Postives = 202/257 (78.60%), Query Frame = 2

Query:    2 LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGM-----LNKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPE----------------------ALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLA 691
            LKFDFLGKDSI+Y N VEVE  V+ AI QF++GK+  DDLFD+LDT+KLNAHLKELMPGLTAKVFRTYNASITLD M     L++ T  GDVA K+ VYQ ANKEVAIICNHQRTVSK+HSAQM RL EKIE+LKG+LK+L+ DL R  KGKPPL K+SDGK KRNL  +                      ++ +K+AQTN KIEKMERD +TKEDLKTVALGTSKINYLDPRITVAWCKRH+VPIEKIFNKSLLA
Sbjct:  521 LKFDFLGKDSIRYQNEVEVEPRVFSAIEQFRSGKEGGDDLFDQLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMVRCKLLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMVRLNEKIEELKGLLKELQEDLTRVNKGKPPL-KNSDGKPKRNLNLKRYKGKLLKLIQKLRKWSETRRLSVTKKIAQTNTKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHDVPIEKIFNKSLLA 776          

BLAST of DR908150 vs. ExPASy Swiss-Prot
Match: TOP1_CAEEL (DNA topoisomerase 1 OS=Caenorhabditis elegans GN=top-1 PE=2 SV=1)

HSP 1 Score: 207.608 bits (527), Expect = 5.360e-53
Identity = 113/228 (49.56%), Postives = 145/228 (63.60%), Query Frame = 2

Query:    2 LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGD-VAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 682
            ++FDFLGKDSI+Y N V VE  VYK +  F  GK  +DDLFD+LDTA LN HL+ LM GLT KVFRTYNASITL   L K T   D VA KI  Y RAN++VAI+CNHQR VSK     M +L +KI+D K  +K+    L                K  R    E  ++K  +   +++K++     K++ K +ALGTSK+NY+DPRITVAWCK+ EVP+EK+F K+
Sbjct:  574 VEFDFLGKDSIRYFNRVSVEKRVYKNLKIFMEGKAPSDDLFDRLDTATLNDHLRSLMDGLTVKVFRTYNASITLQEQLIKLTNPKDNVAAKILSYNRANRQVAILCNHQRAVSKGFDESMQKLEQKIKDKKKEVKEAEAAL----------------KSARGAEKEKAQKKYDRLKEQLKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKVFTKT 785          

BLAST of DR908150 vs. ExPASy Swiss-Prot
Match: TOP1_CERAE (DNA topoisomerase 1 OS=Cercopithecus aethiops GN=TOP1 PE=2 SV=1)

HSP 1 Score: 203.756 bits (517), Expect = 7.740e-52
Identity = 113/228 (49.56%), Postives = 149/228 (65.35%), Query Frame = 2

Query:    2 LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 682
            ++FDFLGKDSI+Y N V VE  V+K +  F   K+  DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D ++  KI  Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL ++ K    +MKD+  K+      E+ ++ + +   ++ K+E     +E+ K +ALGTSK+NYLDPRITVAWCK+  VPIEKI+NK+
Sbjct:  527 VEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRDL-KSAKADAKVMKDAKTKK----VVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKT 749          

BLAST of DR908150 vs. ExPASy Swiss-Prot
Match: TOP1_HUMAN (DNA topoisomerase 1 OS=Homo sapiens GN=TOP1 PE=1 SV=2)

HSP 1 Score: 203.371 bits (516), Expect = 1.011e-51
Identity = 113/228 (49.56%), Postives = 149/228 (65.35%), Query Frame = 2

Query:    2 LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 682
            ++FDFLGKDSI+Y N V VE  V+K +  F   K+  DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D ++  KI  Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL ++ K    +MKD+  K+      E+ ++ + +   ++ K+E     +E+ K +ALGTSK+NYLDPRITVAWCK+  VPIEKI+NK+
Sbjct:  525 VEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADARRDL-KSAKADAKVMKDAKTKK----VVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKT 747          

BLAST of DR908150 vs. ExPASy Swiss-Prot
Match: TOP1_RAT (DNA topoisomerase 1 OS=Rattus norvegicus GN=Top1 PE=2 SV=1)

HSP 1 Score: 202.216 bits (513), Expect = 2.252e-51
Identity = 113/228 (49.56%), Postives = 148/228 (64.91%), Query Frame = 2

Query:    2 LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 682
            ++FDF GKDSI+Y N V VE  V+K +  F   K+  DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D +V  KI  Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL ++ K    +MKD+  K+      E+ ++ + +   ++ K+E     +E+ K +ALGTSK+NYLDPRITVAWCK+  VPIEKI+NK+
Sbjct:  527 VEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARKDL-KSAKADAKVMKDAKTKK----VVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKT 749          

BLAST of DR908150 vs. ExPASy Swiss-Prot
Match: TOP1_MOUSE (DNA topoisomerase 1 OS=Mus musculus GN=Top1 PE=1 SV=2)

HSP 1 Score: 201.83 bits (512), Expect = 2.941e-51
Identity = 113/228 (49.56%), Postives = 148/228 (64.91%), Query Frame = 2

Query:    2 LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 682
            ++FDF GKDSI+Y N V VE  V+K +  F   K+  DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D +V  KI  Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL ++ K    +MKD+  K+      E+ ++ + +   ++ K+E     +E+ K +ALGTSK+NYLDPRITVAWCK+  VPIEKI+NK+
Sbjct:  527 VEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDL-KSAKADAKVMKDAKTKK----VVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKT 749          

BLAST of DR908150 vs. ExPASy Swiss-Prot
Match: TOP1_CRIGR (DNA topoisomerase 1 OS=Cricetulus griseus GN=TOP1 PE=2 SV=1)

HSP 1 Score: 201.83 bits (512), Expect = 2.941e-51
Identity = 113/228 (49.56%), Postives = 148/228 (64.91%), Query Frame = 2

Query:    2 LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 682
            ++FDF GKDSI+Y N V VE  V+K +  F   K+  DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D +V  KI  Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL ++ K    +MKD+  K+      E+ ++ + +   ++ K+E     +E+ K +ALGTSK+NYLDPRITVAWCK+  VPIEKI+NK+
Sbjct:  527 VEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDL-KSAKADAKVMKDAKTKK----VVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKT 749          

BLAST of DR908150 vs. ExPASy Swiss-Prot
Match: TOP1_XENLA (DNA topoisomerase 1 OS=Xenopus laevis GN=top1 PE=2 SV=1)

HSP 1 Score: 199.519 bits (506), Expect = 1.460e-50
Identity = 113/235 (48.09%), Postives = 152/235 (64.68%), Query Frame = 2

Query:    2 LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGT-GDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLASLLG 703
            ++FDF GKDSI+Y N V VE  V+K +  F   K+ +DDLFD+L+T+ LN HL++LM GLTAKVFRTYNASITL   L++ T  D +V  KI  Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R +    K  K       D K K+ +  E+ ++ + +   ++ K+E     +E+ K +ALGTSK+NYLDPRI+VAWCK++ VPIEKI+NK+   +LLG
Sbjct:  581 VEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPDDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLDELTNSDDNVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQGKIDAKKDQLADARREF---KSAKADAKVRRDEKTKKLV--ESKKKAVQRIEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKYGVPIEKIYNKTQRKNLLG 810          

BLAST of DR908150 vs. ExPASy Swiss-Prot
Match: TOP1M_HUMAN (DNA topoisomerase I, mitochondrial OS=Homo sapiens GN=TOP1MT PE=2 SV=1)

HSP 1 Score: 197.978 bits (502), Expect = 4.247e-50
Identity = 110/228 (48.25%), Postives = 140/228 (61.40%), Query Frame = 2

Query:    2 LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGT-GDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 682
            ++FDFLGKD I+Y N V VE PVYK +  F   K   DDLFD+L T  LN HL+ELM GLTAKVFRTYNASITL   L   T  +  +A KI  Y RAN+ VAI+CNHQR    T    M  L  KI+  K  + + R +L RA+          DGK +  L  E   R + +   ++ ++      KE+ K VALGTSK+NYLDPRI++AWCKR  VP+EKI++K+
Sbjct:  361 VEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEH---KAQGDGKSRSVL--EKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKT 583