CX069433

BLAST of CX069433 vs. ExPASy Swiss-Prot
Match: CUL4B_HUMAN (Cullin-4B OS=Homo sapiens GN=CUL4B PE=1 SV=3)

HSP 1 Score: 301.982 bits (772), Expect = 2.783e-81
Identity = 144/201 (71.64%), Postives = 172/201 (85.57%), Query Frame = -2

Query:  246 LSKYSGRRLMWQNSLGHCVLKAEFPKGKKELAVSLFQTVVLMLFNDAQKLSFQDIKDATGIEDKELRRTLQSLACGKVRVLQKLPKGRDVEDDDSFVFNEGFTAPLYRIKVNAIQMKETVEENTSTTERVFQDRQYQVDAAIVRIMKTRKVLSHTLLITELFQQLKFPIKPADLKKRIESLIDREYLERDKNNPQIYNYLA 848
            L K+SGR+L WQ++LGHCVLKAEF +GKKEL VSLFQT+VL++FN+ ++ S ++IK ATGIED ELRRTLQSLACGK RVL K PKG+D+ED D F+ N+ F   L+RIK+N IQMKETVEE  STTERVFQDRQYQ+DAAIVRIMK RK LSH LL++E++ QLKFP+KPADLKKRIESLIDR+Y+ERDK NP  YNY+A
Sbjct:  695 LGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 895          

BLAST of CX069433 vs. ExPASy Swiss-Prot
Match: CUL4A_HUMAN (Cullin-4A OS=Homo sapiens GN=CUL4A PE=1 SV=3)

HSP 1 Score: 292.352 bits (747), Expect = 2.205e-78
Identity = 142/201 (70.65%), Postives = 167/201 (83.08%), Query Frame = -2

Query:  246 LSKYSGRRLMWQNSLGHCVLKAEFPKGKKELAVSLFQTVVLMLFNDAQKLSFQDIKDATGIEDKELRRTLQSLACGKVRVLQKLPKGRDVEDDDSFVFNEGFTAPLYRIKVNAIQMKETVEENTSTTERVFQDRQYQVDAAIVRIMKTRKVLSHTLLITELFQQLKFPIKPADLKKRIESLIDREYLERDKNNPQIYNYLA 848
            L K+SGR+L WQ +LGH VLKAEF +GKKE  VSLFQT+VL++FN+    SF++IK ATGIED ELRRTLQSLACGK RVL K PKG++VED D F+FN  F   L+RIK+N IQMKETVEE  STTERVFQDRQYQ+DAAIVRIMK RK L H LL++EL+ QLKFP+KP DLKKRIESLIDR+Y+ERDK+NP  Y+Y+A
Sbjct:  559 LGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKDNPNQYHYVA 759          

BLAST of CX069433 vs. ExPASy Swiss-Prot
Match: CUL4A_MOUSE (Cullin-4A OS=Mus musculus GN=Cul4a PE=2 SV=1)

HSP 1 Score: 290.041 bits (741), Expect = 1.094e-77
Identity = 140/201 (69.65%), Postives = 167/201 (83.08%), Query Frame = -2

Query:  246 LSKYSGRRLMWQNSLGHCVLKAEFPKGKKELAVSLFQTVVLMLFNDAQKLSFQDIKDATGIEDKELRRTLQSLACGKVRVLQKLPKGRDVEDDDSFVFNEGFTAPLYRIKVNAIQMKETVEENTSTTERVFQDRQYQVDAAIVRIMKTRKVLSHTLLITELFQQLKFPIKPADLKKRIESLIDREYLERDKNNPQIYNYLA 848
            L K+SGR+L WQ +LGH VLKA+F +GKKE  VSLFQT+VL++FN+    SF++IK ATGIED ELRRTLQSLACGK RVL K PKG++VED D F+FN  F   L+RIK+N IQMKETVEE  STTERVFQDRQYQ+DAAIVRIMK RK L H LL++EL+ QLKFP+KP DLKKRIESLIDR+Y+ERDK++P  Y+Y+A
Sbjct:  559 LGKHSGRKLQWQTTLGHAVLKADFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNADFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKDSPNQYHYVA 759          

BLAST of CX069433 vs. ExPASy Swiss-Prot
Match: CUL4_DICDI (Cullin-4 OS=Dictyostelium discoideum GN=culD PE=3 SV=1)

HSP 1 Score: 210.305 bits (534), Expect = 1.102e-53
Identity = 118/236 (50.00%), Postives = 153/236 (64.83%), Query Frame = -2

Query:  246 LSKYSGRRLMWQNSLGHCVLKAEFPKGKKELAVSLFQTVVLMLFNDA---QKLSFQDIKDATGIEDKELRRTLQSLACGKVRVL-QK-------------------------------LPKGRDVEDDDSFVFNEGFTAPLYRIKVNAIQMKETVEENTSTTERVFQDRQYQVDAAIVRIMKTRKVLSHTLLITELFQQLKFPIKPADLKKRIESLIDREYLERDKNNPQIYNYLA 848
            LSK++G+ L WQN+L +CVLKA F +GKKEL+VSLFQT++L LFND     +LSF+DI+  TG+   EL++ L SL   K  +L QK                                 K + +++ D+F+FN  F++ L++IKVN+IQ++ETVEEN  T E +  DRQYQVDAAIVRIMKTRK L+H LLI+EL   LKF  KP DLKKRIE LI++EYL RD  N  IYNY+A
Sbjct:  567 LSKHNGKTLKWQNALSYCVLKANFIQGKKELSVSLFQTIILYLFNDVIDGGELSFRDIQANTGLAIPELKKNLLSLCSSKSDILIQKKSSTSSNTSSNTSSNTSSSASGSASGGASGGATKTKVIDETDTFLFNSKFSSKLFKIKVNSIQIQETVEENQKTNENIISDRQYQVDAAIVRIMKTRKTLAHNLLISELVSLLKFQPKPVDLKKRIEILIEKEYLCRDPENAMIYNYMA 802          

BLAST of CX069433 vs. ExPASy Swiss-Prot
Match: CUL4_SCHPO (Cullin-4 OS=Schizosaccharomyces pombe GN=cul4 PE=1 SV=1)

HSP 1 Score: 174.866 bits (442), Expect = 5.131e-43
Identity = 89/205 (43.41%), Postives = 136/205 (66.34%), Query Frame = -2

Query:  249 LSKYSGRRLMWQNSLGHCVLKAEFPKGKKELAVSLFQTVVLMLFNDA---QKLSFQDIKDATGIEDKELRRTLQSLACGKVRVLQKLPKGRDVEDDDSFVFNEGFTAPLYRIKVNAIQMKETVEENTSTTERVFQDRQYQVDAAIVRIMKTRKVLSHTLLITELFQQLKFPIKP--ADLKKRIESLIDREYLERDKNNPQIYNYL 848
            LSK  G+++ W  SLGHC++KA FP G KEL++SLFQ  VL+ FN+    + +S+QD+K +T + D +L RTLQSL+C ++R L  +PK +    D  F  NE FT  LYR+K+N I +KE  +EN+   E+V +DRQ+++ A+IVR+MK ++ + H  L+  +   +K    P  +D+K  IE L+++EYLER+ N+  IY Y+
Sbjct:  531 LSKQVGKKISWYASLGHCIVKARFPLGNKELSISLFQACVLLQFNNCLGGEGISYQDLKKSTELSDIDLTRTLQSLSCARIRPLVMVPKSKKPSPDTMFYVNEKFTDKLYRVKINQIYLKEERQENSDVQEQVVRDRQFELQASIVRVMKQKEKMKHDDLVQYVINNVKDRGIPLVSDVKTAIEKLLEKEYLEREDND--IYTYV 733          

BLAST of CX069433 vs. ExPASy Swiss-Prot
Match: CUL3_DICDI (Cullin-3 OS=Dictyostelium discoideum GN=culC PE=3 SV=1)

HSP 1 Score: 169.474 bits (428), Expect = 2.156e-41
Identity = 95/237 (40.08%), Postives = 140/237 (59.07%), Query Frame = -2

Query:  246 LSKYSGRRLMWQNSLGHCVLKAEFPKGKKELAVSLFQTVVLMLFNDAQKLSFQDIKDATGIEDKELRRTLQSLACGKVRVLQK-LPK---------------------------------GRDVEDDDSFVFNEGFTAPLYRIKVNAIQMKETVEENTSTTERVFQDRQYQVDAAIVRIMKTRKVLSHTLLITELFQQL--KFPIKPADLKKRIESLIDREYLERDKNNPQIYNYLA 848
            LS ++GR L+WQ ++G   +KA FP    EL VS +Q V+L+LFND  KL+F++I D TGI   +L+R L +L   K ++L + LP                                   + +++ D F FN  F + L+R+KV A+  KET  E   T ++V +DR++Q++A+IVRIMK RK L H+ L++E+ +QL  +F   P  +KKRIESLI+REYLER K + +IYNY+A
Sbjct:  533 LSNHNGRLLLWQTNMGTAEIKANFPSKSHELQVSSYQMVILLLFNDQSKLTFKEIADQTGIPTIDLKRNLLALTNPKNKILDRELPSTTSSTTTTTTTATSSSTSTSPSSSSSSISTPTPSKSIDESDVFAFNTKFKSKLFRVKVMAVVQKETPVEEKETRDKVDEDRKHQIEASIVRIMKARKTLEHSNLVSEVIKQLQSRFVPNPVIVKKRIESLIEREYLERSKQDRKIYNYMA 769          

BLAST of CX069433 vs. ExPASy Swiss-Prot
Match: CUL3_SCHPO (Cullin-3 OS=Schizosaccharomyces pombe GN=cul3 PE=1 SV=2)

HSP 1 Score: 167.162 bits (422), Expect = 1.070e-40
Identity = 92/208 (44.23%), Postives = 133/208 (63.94%), Query Frame = -2

Query:  246 LSKYSGRRLMWQNSLGHCVLKAEFPKGKKELAVSLFQTVVLMLFNDAQK---LSFQDIKDATGIEDKELRRTLQSLACGKVRVLQKLPKGRDVEDDDSFVFNEGFTAPLYRIKVNAIQMK--ETVEENTSTTERVFQDRQYQVDAAIVRIMKTRKVLSHTLLITELFQQL--KFPIKPADLKKRIESLIDREYLERDKNNPQIYNYLA 848
            LSK++GR+L+W  S+G   ++  F   K +L VS   +V+L+LF D ++   L F++I + T IE  +L+R LQSLAC K ++L K PKGR+V   D F FNE F + L RIK++ +     E   E   T E+V + R++Q DA IVR+MK RKV  H  L+ E+ +QL  +F   P  +K+RIE+LI+REYL+R  +N +IY YLA
Sbjct:  578 LSKHTGRKLLWYPSMGSADVRVNFKDRKYDLNVSTIASVILLLFQDLKENQCLIFEEILEKTNIEVGDLKRNLQSLACAKYKILLKDPKGREVNAGDKFYFNENFVSNLARIKISTVAQTRVEDDSERKRTLEKVDESRKHQADACIVRVMKDRKVCEHNQLMAEVTRQLNPRFHPSPMMIKRRIEALIEREYLQRQADNGRIYEYLA 785          

BLAST of CX069433 vs. ExPASy Swiss-Prot
Match: CUL3_XENTR (Cullin-3 OS=Xenopus tropicalis GN=cul3 PE=2 SV=1)

HSP 1 Score: 158.688 bits (400), Expect = 3.805e-38
Identity = 94/229 (41.05%), Postives = 138/229 (60.26%), Query Frame = -2

Query:  246 LSKYSGRRLMWQNSLGHCVLKAEF--PKGKKE--------------------LAVSLFQTVVLMLFNDAQKLSFQDIKDATGIEDKELRRTLQSLACGK--VRVLQKLPKGRDVEDDDSFVFNEGFTAPLYRIKVNAIQMK--ETVEENTSTTERVFQDRQYQVDAAIVRIMKTRKVLSHTLLITELFQQLK--FPIKPADLKKRIESLIDREYLERDKNNPQIYNYLA 848
            L+K+SGR+L  Q+ +G   L A F  P  K++                    L VS FQ  +LMLFN+ +K +F++I+  T I ++EL R LQSLACGK   RVL K PK +++E    F  N+ FT+ L+R+K+  +  K  E+  E   T ++V  DR+++++AAIVRIMK+RK + H +L+ E+ QQLK  F   P  +KKRIE LI+REYL R   + ++Y Y+A
Sbjct:  540 LAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHMFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 768          

BLAST of CX069433 vs. ExPASy Swiss-Prot
Match: CUL3_HUMAN (Cullin-3 OS=Homo sapiens GN=CUL3 PE=1 SV=2)

HSP 1 Score: 158.688 bits (400), Expect = 3.805e-38
Identity = 94/229 (41.05%), Postives = 139/229 (60.70%), Query Frame = -2

Query:  246 LSKYSGRRLMWQNSLGHCVLKAEF--PKGKKE--------------------LAVSLFQTVVLMLFNDAQKLSFQDIKDATGIEDKELRRTLQSLACGK--VRVLQKLPKGRDVEDDDSFVFNEGFTAPLYRIKVNAIQMK--ETVEENTSTTERVFQDRQYQVDAAIVRIMKTRKVLSHTLLITELFQQLK--FPIKPADLKKRIESLIDREYLERDKNNPQIYNYLA 848
            L+K+SGR+L  Q+ +G   L A F  P  K++                    L VS FQ  +LMLFN+ +K +F++I+  T I ++EL R LQSLACGK   RVL K PK +++E+   F  N+ FT+ L+R+K+  +  K  E+  E   T ++V  DR+++++AAIVRIMK+RK + H +L+ E+ QQLK  F   P  +KKRIE LI+REYL R   + ++Y Y+A
Sbjct:  540 LAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 768          

BLAST of CX069433 vs. ExPASy Swiss-Prot
Match: CUL3_MOUSE (Cullin-3 OS=Mus musculus GN=Cul3 PE=1 SV=1)

HSP 1 Score: 158.303 bits (399), Expect = 4.970e-38
Identity = 94/229 (41.05%), Postives = 138/229 (60.26%), Query Frame = -2

Query:  246 LSKYSGRRLMWQNSLGHCVLKAEF--PKGKKE--------------------LAVSLFQTVVLMLFNDAQKLSFQDIKDATGIEDKELRRTLQSLACGK--VRVLQKLPKGRDVEDDDSFVFNEGFTAPLYRIKVNAIQMK--ETVEENTSTTERVFQDRQYQVDAAIVRIMKTRKVLSHTLLITELFQQLK--FPIKPADLKKRIESLIDREYLERDKNNPQIYNYLA 848
            L+K+SGR+L  Q+ +G   L A F  P  K++                    L VS FQ  +LMLFN+ +K +F++I+  T I ++EL R LQSLACGK   RVL K PK +++E    F  N+ FT+ L+R+K+  +  K  E+  E   T ++V  DR+++++AAIVRIMK+RK + H +L+ E+ QQLK  F   P  +KKRIE LI+REYL R   + ++Y Y+A
Sbjct:  540 LAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 768