CX043968

BLAST of CX043968 vs. ExPASy Swiss-Prot
Match: C72A1_CATRO (Secologanin synthase OS=Catharanthus roseus GN=CYP72A1 PE=2 SV=1)

HSP 1 Score: 132.88 bits (333), Expect = 1.637e-30
Identity = 65/172 (37.79%), Postives = 101/172 (58.72%), Query Frame = -1

Query:  178 PDWQEKLRGEVLELFGQKNPAPDGIGKLKPMSRVINEFLRRFPPAVNISRNVEREVRLGKSIFPANMELVIPILAIPHAPQIWGEDVDFFKPERFADGGAKXXXXXXXXXXXXXSGPRICGGLNFAATEAKIALSMILQRYRFNLSPSYVPSPVLVGPFPPQHGLQVIFHPL 693
            P+WQE+ R EVL+ FG+  P  + +  LK +S ++ E LR +PP +++++ V ++ +LG    PA  ++++P + +     IWGED   F P RF DG A               GPR+C G NFA  +AK+ L+MILQR++F+++PSYV +P  +    PQ G  VI+  L
Sbjct:  352 PEWQERAREEVLQAFGKNKPEFERLNHLKYVSMILYEVLRLYPPVIDLTKIVHKDTKLGSYTIPAGTQVMLPTVMLHREKSIWGEDAMEFNPMRFVDGVAN-ATKNNVTYLPFSWGPRVCLGQNFALLQAKLGLAMILQRFKFDVAPSYVHAPFTILTVQPQFGSHVIYKKL 522          

BLAST of CX043968 vs. ExPASy Swiss-Prot
Match: CP3A5_HUMAN (Cytochrome P450 3A5 OS=Homo sapiens GN=CYP3A5 PE=1 SV=1)

HSP 1 Score: 80.8777 bits (198), Expect = 7.382e-15
Identity = 48/146 (32.88%), Postives = 75/146 (51.37%), Query Frame = -1

Query:  265 TPPDWQEKLRGEVLELFGQKNPAP-DGIGKLKPMSRVINEFLRRFPPAVNISRNVEREVRLGKSIFPANMELVIPILAIPHAPQIWGEDVDFFKPERFADGGAKXXXXXXXXXXXXXSGPRICGGLNFAATEAKIALSMILQRYRF 699
            T PD Q+KL+ E+  +   K P   D + +++ +  V+NE LR FP A+ + R  +++V +     P    +VIP  A+ H P+ W E  + F+PERF+    K             +GPR C G+ FA    K+AL  +LQ + F
Sbjct:  323 THPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEE-FRPERFS---KKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSF 464          

BLAST of CX043968 vs. ExPASy Swiss-Prot
Match: CP3AO_SHEEP (Cytochrome P450 3A24 OS=Ovis aries GN=CYP3A24 PE=2 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 2.375e-13
Identity = 46/146 (31.51%), Postives = 73/146 (50.00%), Query Frame = -1

Query:  265 TPPDWQEKLRGEVLELFGQKNPAP-DGIGKLKPMSRVINEFLRRFPPAVNISRNVEREVRLGKSIFPANMELVIPILAIPHAPQIWGEDVDFFKPERFADGGAKXXXXXXXXXXXXXSGPRICGGLNFAATEAKIALSMILQRYRF 699
            T PD Q+KL+ E+   F  K P   D + +++ +  V+NE LR FP AV + R  +++V +     P    + +PI  +   PQ+W E  + F+PERF+                  +GPR C G+ FA    K+A+  +LQ + F
Sbjct:  323 THPDVQQKLQEEIDATFPNKAPPTYDVLAQMEYLDMVVNETLRMFPIAVRLDRLCKKDVEIHGVSIPKGTAVTVPIFVLHRDPQLWPEPEE-FRPERFSK--KNKDSINPYVYLPFGTGPRNCIGMRFAIMNMKLAIVRVLQNFSF 465          

BLAST of CX043968 vs. ExPASy Swiss-Prot
Match: CP3AB_MOUSE (Cytochrome P450 3A11 OS=Mus musculus GN=Cyp3a11 PE=1 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 3.102e-13
Identity = 48/146 (32.88%), Postives = 74/146 (50.68%), Query Frame = -1

Query:  265 TPPDWQEKLRGEVLELFGQKNPAP-DGIGKLKPMSRVINEFLRRFPPAVNISRNVEREVRLGKSIFPANMELVIPILAIPHAPQIWGEDVDFFKPERFADGGAKXXXXXXXXXXXXXSGPRICGGLNFAATEAKIALSMILQRYRF 699
            T PD Q+KL+ E+ E    K P   D + +++ +  V+NE LR +P A  + R  +++V L     P    ++IP  A+ H PQ W E  + F+PERF+                  +GPR C G+ FA    K+AL+ I+Q + F
Sbjct:  324 THPDIQKKLQDEIDEALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIANRLERVCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWSEPEE-FQPERFSK--ENKGSIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSF 466          

BLAST of CX043968 vs. ExPASy Swiss-Prot
Match: CP3AT_PIG (Cytochrome P450 3A29 OS=Sus scrofa GN=CYP3A29 PE=2 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 6.910e-13
Identity = 44/146 (30.14%), Postives = 72/146 (49.32%), Query Frame = -1

Query:  265 TPPDWQEKLRGEVLELFGQKNPAP-DGIGKLKPMSRVINEFLRRFPPAVNISRNVEREVRLGKSIFPANMELVIPILAIPHAPQIWGEDVDFFKPERFADGGAKXXXXXXXXXXXXXSGPRICGGLNFAATEAKIALSMILQRYRF 699
            T PD Q+KL+ E+   F  K P   D + +++ +  V+NE LR +P A  + R  +++V +     P    +V+P+  +   P +W E  + F+PERF+                  +GPR C G+ FA    K+AL  +LQ + F
Sbjct:  323 THPDVQQKLQEEIEATFPNKAPPTYDALAQMEYLDMVVNETLRLYPIAARLERACKKDVEIHGVFVPKGTVVVVPVFVLHRDPDLWPEPEE-FRPERFSK--KHKDTINPYTYLPFGTGPRNCIGMRFALMNMKLALVRVLQNFSF 465          

BLAST of CX043968 vs. ExPASy Swiss-Prot
Match: C13A6_CAEEL (Putative cytochrome P450 CYP13A6 OS=Caenorhabditis elegans GN=cyp-13A6 PE=2 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 6.910e-13
Identity = 56/164 (34.15%), Postives = 78/164 (47.56%), Query Frame = -1

Query:  223 TPPDWQEKLRGEVLELFGQKNPAP----DGIGKLKPMSRVINEFLRRFPPAVNIS-RNVEREVRLGKSIFPANMELVIPILAIPHAPQIWGEDVDFFKPERFADGGAKXXXXXXXXXXXXXSGPRICGGLNFAATEAKIALSMILQRYRFNLSPSYVPSPVLVG 699
            T P+ Q KL+ EV     ++ P P    D + KLK +  V+ E LR +P     + R   RE  +    F   M + +    + H P+IWGEDV+ FKPER+ + GA              SGPR C G+  A  E KI L+ IL+ Y F  + +      LVG
Sbjct:  342 THPEIQTKLQEEV----DRECPDPEIFFDHLSKLKYLECVMKETLRLYPLGTTANTRKCMRETTINGVNFDEGMNIQVDTWTLHHNPRIWGEDVEDFKPERW-ENGACEHLEHNGSYIPFGSGPRQCIGMRLAQMEQKILLAQILKEYSFRTTKNTQIPVKLVG 500          

BLAST of CX043968 vs. ExPASy Swiss-Prot
Match: CP343_HUMAN (Cytochrome P450 3A43 OS=Homo sapiens GN=CYP3A43 PE=1 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 9.024e-13
Identity = 44/146 (30.14%), Postives = 74/146 (50.68%), Query Frame = -1

Query:  265 TPPDWQEKLRGEVLELFGQKNPAP-DGIGKLKPMSRVINEFLRRFPPAVNISRNVEREVRLGKSIFPANMELVIPILAIPHAPQIWGEDVDFFKPERFADGGAKXXXXXXXXXXXXXSGPRICGGLNFAATEAKIALSMILQRYRF 699
            T PD Q+KL+ E+  +   K P   D + +++ +  V+NE LR FP    ++R  ++++ +     P  + +++PI A+ H P+ W E  + F PERF+                  +GPR C G+ FA T  K+A+   LQ + F
Sbjct:  323 THPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEP-EKFCPERFSK--KNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSF 465          

BLAST of CX043968 vs. ExPASy Swiss-Prot
Match: C13A8_CAEEL (Putative cytochrome P450 CYP13A8 OS=Caenorhabditis elegans GN=cyp-13A8 PE=2 SV=2)

HSP 1 Score: 73.1738 bits (178), Expect = 1.539e-12
Identity = 51/144 (35.42%), Postives = 69/144 (47.92%), Query Frame = -1

Query:  265 PDWQEKLRGEVLELFGQKNPAPDGIGKLKPMSRVINEFLRRFPPAVNI-SRNVEREVRLGKSIFPANMELVIPILAIPHAPQIWGEDVDFFKPERFADGGAKXXXXXXXXXXXXXSGPRICGGLNFAATEAKIALSMILQRYRF 693
            P  Q KL+ EV +         D + KLK M  VI E LR FP A    SR   R   +G+ I  A ++++I    + H   +WG DV+ FKPER+                   +GPR+C G+ FA  E K  LS IL++Y F
Sbjct:  340 PKIQSKLQDEVDKECPNDEITFDQLSKLKYMDNVIKESLRLFPFASFANSRRCMRNTVIGEQIVEAGVDVMIDTWTLHHDKNVWGNDVEEFKPERW-----DSPLTPQQAYLSFGAGPRVCLGMRFALLEQKGLLSHILKKYTF 478          

BLAST of CX043968 vs. ExPASy Swiss-Prot
Match: CP3AL_CALJA (Cytochrome P450 3A21 OS=Callithrix jacchus GN=CYP3A21 PE=2 SV=1)

HSP 1 Score: 72.7886 bits (177), Expect = 2.010e-12
Identity = 46/146 (31.51%), Postives = 75/146 (51.37%), Query Frame = -1

Query:  265 TPPDWQEKLRGEVLELFGQKNPAP-DGIGKLKPMSRVINEFLRRFPPAVNISRNVEREVRLGKSIFPANMELVIPILAIPHAPQIWGEDVDFFKPERFADGGAKXXXXXXXXXXXXXSGPRICGGLNFAATEAKIALSMILQRYRF 699
            T PD Q+KL+ E+  +   K PA  D + +++ +  V+NE LR FP A+ + R  +++V +     P  + ++IP  A+ + P+ W E  + F PERF+                  +GPR C G+ FA    K+AL  +LQ + F
Sbjct:  323 THPDVQQKLQEEIDAVLPNKAPATYDTVLQMEYLDMVVNETLRLFPLAMRLERVCKKDVEINGVFIPKGVVVMIPSYALHYDPKYWTEP-EKFLPERFSKN--NKDNIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSF 465          

BLAST of CX043968 vs. ExPASy Swiss-Prot
Match: CP3AJ_CAPAE (Cytochrome P450 3A19 (Fragment) OS=Capra aegagrus GN=CYP3A19 PE=2 SV=1)

HSP 1 Score: 72.7886 bits (177), Expect = 2.010e-12
Identity = 45/146 (30.82%), Postives = 73/146 (50.00%), Query Frame = -1

Query:  265 TPPDWQEKLRGEVLELFGQKNPAP-DGIGKLKPMSRVINEFLRRFPPAVNISRNVEREVRLGKSIFPANMELVIPILAIPHAPQIWGEDVDFFKPERFADGGAKXXXXXXXXXXXXXSGPRICGGLNFAATEAKIALSMILQRYRF 699
            T PD Q+KL+ E+   F  K P   D + +++ +  V+NE LR FP A  + R  +++V +     P    +++P+  + + P+ W E  + F+PERF+                  +GPR C G+ FA    K+AL  ILQ + F
Sbjct:   34 THPDVQQKLQEEIDATFPNKAPPTYDALVQMEYLDMVVNETLRMFPIAGRLERLCKKDVEIHGVSIPKGTTVMVPLFVLHNNPEFWPEPEE-FRPERFSK--KNKDGINPYVYLPFGTGPRNCVGMRFALMNIKLALVRILQNFSF 176