DY258096

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS_ARATH (Hydroxymethylglutaryl-CoA synthase OS=Arabidopsis thaliana GN=HMGS PE=2 SV=2)

HSP 1 Score: 443.351 bits (1139), Expect = 1.434e-123
Identity = 214/260 (82.31%), Postives = 236/260 (90.77%), Query Frame = 1

Query:  223 MAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCNKYQE-TGRETNFSFQRLINFWSIPPYNRLGQKNF 999
            MAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQ+C+AFC+E+EDVISMS  AVT+L EKYKIDP QIGRLEVGSETVIDKSKSIKTFLMQ+FEK GNTD+EGVDSTNACYGGTAAL NCVNWVES+SWDGRYGLV+CTDSAVYAEGPARPTGGAAA+ ML+GPDAP+ FESKLR SHM+H YDFYKPNLASEYPVVDGKLSQTCYLMALD+CYK LCNK+++  G+E + +    I F S  PYN+L QK+F
Sbjct:    1 MAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQDCLAFCTELEDVISMSFNAVTSLFEKYKIDPNQIGRLEVGSETVIDKSKSIKTFLMQLFEKCGNTDVEGVDSTNACYGGTAALLNCVNWVESNSWDGRYGLVICTDSAVYAEGPARPTGGAAAIAMLIGPDAPIVFESKLRASHMAHVYDFYKPNLASEYPVVDGKLSQTCYLMALDSCYKHLCNKFEKIEGKEFSINDADYIVFHS--PYNKLVQKSF 258          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS1_PONAB (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Pongo abelii GN=HMGCS1 PE=2 SV=1)

HSP 1 Score: 316.62 bits (810), Expect = 2.024e-85
Identity = 154/260 (59.23%), Postives = 192/260 (73.85%), Query Frame = 1

Query:  229 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCNK----YQETGRETNFSFQRLINFWSIPPYNRLGQKN 996
            K+VGI+A++IYFP   V Q  LE +DG + GKYTIGLGQ  M FC++ ED+ S+ +T V NL+E+  +    IGRLEVG+ET+IDKSKS+KT LMQ+FE+ GNTDIEG+D+TNACYGGTAA+FN VNW+ESSSWDGRY LVV  D AVYA G ARPTGG  AV +L+GP+AP+ FE  LRG+HM HAYDFYKP++ SEYP+VDGKLS  CYL ALD CY   C K    +Q+ G + +F+           PY +L QK+
Sbjct:   15 KDVGIVALEIYFPSQYVDQAELEKYDGVAAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKIRAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQKS 274          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS1_HUMAN (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Homo sapiens GN=HMGCS1 PE=1 SV=2)

HSP 1 Score: 316.235 bits (809), Expect = 2.643e-85
Identity = 154/260 (59.23%), Postives = 191/260 (73.46%), Query Frame = 1

Query:  229 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCNK----YQETGRETNFSFQRLINFWSIPPYNRLGQKN 996
            K+VGI+A++IYFP   V Q  LE +DG   GKYTIGLGQ  M FC++ ED+ S+ +T V NL+E+  +    IGRLEVG+ET+IDKSKS+KT LMQ+FE+ GNTDIEG+D+TNACYGGTAA+FN VNW+ESSSWDGRY LVV  D AVYA G ARPTGG  AV +L+GP+AP+ FE  LRG+HM HAYDFYKP++ SEYP+VDGKLS  CYL ALD CY   C K    +Q+ G + +F+           PY +L QK+
Sbjct:   15 KDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKIHAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQKS 274          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS1_CHICK (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Gallus gallus GN=HMGCS1 PE=1 SV=1)

HSP 1 Score: 315.079 bits (806), Expect = 5.889e-85
Identity = 157/260 (60.38%), Postives = 189/260 (72.69%), Query Frame = 1

Query:  229 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCNK----YQETGRETNFSFQRLINFWSIPPYNRLGQKN 996
            K+VGI+A++IYFP   V Q  LE +DG   GKYTIGLGQ  M FCS+ ED+ S+ LT V  L+E+  +    IGRLEVG+ET+IDKSKS+KT LMQ+FE+ GNTD+EG+D+TNACYGGTAALFN +NW+ESSSWDGRY LVV  D AVYA G ARPTGGA AV MLVG +AP+ FE  LRG+HM HAYDFYKP++ SEYPVVDGKLS  CYL ALD CY    NK    +Q+ G +  F+           PY +L QK+
Sbjct:   15 KDVGIVALEIYFPSQYVDQTELEKYDGVDAGKYTIGLGQSKMGFCSDREDINSLCLTVVQKLMERNSLSYDCIGRLEVGTETIIDKSKSVKTVLMQLFEESGNTDVEGIDTTNACYGGTAALFNAINWIESSSWDGRYALVVAGDIAVYATGNARPTGGAGAVAMLVGSNAPLIFERGLRGTHMQHAYDFYKPDMVSEYPVVDGKLSIQCYLSALDRCYSVYRNKIHAQWQKEGTDRGFTLNDFGFMIFHSPYCKLVQKS 274          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS1_CRIGR (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Cricetulus griseus GN=HMGCS1 PE=3 SV=1)

HSP 1 Score: 311.997 bits (798), Expect = 4.985e-84
Identity = 152/260 (58.46%), Postives = 193/260 (74.23%), Query Frame = 1

Query:  229 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCY----KCLCNKYQETGRETNFSFQRLINFWSIPPYNRLGQKN 996
            K+VGI+A++IYFP   V Q  LE +DG   GKYTIGLGQ  M FC++ ED+ S+ LT V NL+E+  +    IGRLEVG+ET+IDKSKS+K+ LMQ+FE+ GNTDIEG+D+TNACYGGTAA+FN VNW+ESSSWDGRY LVV  D A+YA G ARPTGG  AV +L+GP+AP+ F+  LRG+HM HAYDFYKP++ SEYP+VDGKLS  CYL ALD CY    K +  ++Q+ G + +F+        S  PY +L QK+
Sbjct:   15 KDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCTDREDINSLCLTVVQNLMERNSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAIYATGNARPTGGVGAVALLIGPNAPLIFDRGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYRKKIRAQWQKEGNDNDFTLNDFGFMISHSPYCKLVQKS 274          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS1_MOUSE (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Mus musculus GN=Hmgcs1 PE=1 SV=1)

HSP 1 Score: 310.071 bits (793), Expect = 1.894e-83
Identity = 152/260 (58.46%), Postives = 193/260 (74.23%), Query Frame = 1

Query:  229 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCY----KCLCNKYQETGRETNFSFQRLINFWSIPPYNRLGQKN 996
            K+VGI+A++IYFP   V Q  LE +DG   GKYTIGLGQ  M FC++ ED+ S+ LT V  L+E++ +    IGRLEVG+ET+IDKSKS+K+ LMQ+FE+ GNTDIEG+D+TNACYGGTAA+FN VNWVESSSWDGRY LVV  D A+YA G ARPTGG  AV +L+GP+AP+ F+  LRG+HM HAYDFYKP++ SEYPVVDGKLS  CYL ALD CY    K +  ++Q+ G++ +F+           PY +L QK+
Sbjct:   15 KDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCTDREDINSLCLTVVQKLMERHSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWVESSSWDGRYALVVAGDIAIYATGNARPTGGVGAVALLIGPNAPLIFDRGLRGTHMQHAYDFYKPDMLSEYPVVDGKLSIQCYLSALDRCYSVYRKKIRAQWQKEGKDKDFTLNDFGFMIFHSPYCKLVQKS 274          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCSA_DICDI (Hydroxymethylglutaryl-CoA synthase A OS=Dictyostelium discoideum GN=hgsA PE=1 SV=2)

HSP 1 Score: 309.686 bits (792), Expect = 2.474e-83
Identity = 148/261 (56.70%), Postives = 190/261 (72.80%), Query Frame = 1

Query:  220 TMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCYKCLCNKYQETGRETNFSFQRLINFWSIPPYNRLGQKNFG 1002
            T  +N+GI  +++YFP T V QE LE  DG S+GKYT+GLGQ  MAFC + ED+ S+SL AV NL++K+ +DP  IGRLEVG+ETVIDKSKS+KT LM +F K GNT I+G+D+ NACYGGT+AL N + W+ESS WDGR  +VV  D AVY +GPARPTGGA  V ML+GP+AP+ FES LRG HM + YDFYKP++ SEYP VDGKLS +CY  A+D CY      +++   + +FS  ++       PYN+L QK+FG
Sbjct:    2 TKPENIGIHGIEVYFPSTYVAQEDLEKFDGVSQGKYTLGLGQTNMAFCGDREDIYSLSLNAVNNLMDKFNVDPNSIGRLEVGTETVIDKSKSVKTVLMDLFAKHGNTSIDGIDTINACYGGTSALHNALQWMESSYWDGRNAIVVAGDIAVYEKGPARPTGGAGVVAMLIGPNAPITFESGLRGVHMENVYDFYKPDMDSEYPRVDGKLSISCYFRAIDNCYNRYAKAFEKKYGK-SFSLDQVDFALFHSPYNKLVQKSFG 261          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS1_RAT (Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Rattus norvegicus GN=Hmgcs1 PE=1 SV=1)

HSP 1 Score: 309.686 bits (792), Expect = 2.474e-83
Identity = 152/260 (58.46%), Postives = 192/260 (73.85%), Query Frame = 1

Query:  229 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCY----KCLCNKYQETGRETNFSFQRLINFWSIPPYNRLGQKN 996
            K+VGI+A++IYFP   V Q  LE +DG   GKYTIGLGQ  M FC++ ED+ S+ LT V  L+E+  +    IGRLEVG+ET+IDKSKS+K+ LMQ+FE+ GNTDIEG+D+TNACYGGTAA+FN VNW+ESSSWDGRY LVV  D A+YA G ARPTGG  AV +L+GP+APV F+  LRG+HM HAYDFYKP++ SEYPVVDGKLS  CYL ALD CY    K +  ++Q+ G++ +F+           PY +L QK+
Sbjct:   15 KDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCTDREDINSLCLTVVQKLMERNSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAIYASGNARPTGGVGAVALLIGPNAPVIFDRGLRGTHMQHAYDFYKPDMLSEYPVVDGKLSIQCYLSALDRCYSVYRKKIRAQWQKEGKDKDFTLNDFGFMIFHSPYCKLVQKS 274          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS2_HUMAN (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Homo sapiens GN=HMGCS2 PE=1 SV=1)

HSP 1 Score: 306.22 bits (783), Expect = 7.427e-83
Identity = 152/279 (54.48%), Postives = 196/279 (70.25%), Query Frame = 1

Query:  172 HIFFIWAFSVFENQIKTMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCY----KCLCNKYQETGRETNFSFQRLINFWSIPPYNRLGQKN 996
            H  F  A +V   +  T  K+VGILA+++YFP   V Q  LE ++    GKYT+GLGQ  M FCS  ED+ S+ LT V  L+E+ ++    +GRLEVG+ET+IDKSK++KT LM++F+  GNTDIEG+D+TNACYGGTA+LFN  NW+ESSSWDGRY +VVC D AVY  G ARPTGGA AV ML+GP AP+A E  LRG+HM + YDFYKPNLASEYP+VDGKLS  CYL ALD CY    K + N++++ G +  F+   L       P+ ++ QK+
Sbjct:   33 HQRFSTASAVPLAKTDTWPKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTLDDLQYMIFHTPFCKMVQKS 311          

HSP 2 Score: 21.1718 bits (43), Expect = 7.427e-83
Identity = 8/12 (66.67%), Postives = 11/12 (91.67%), Query Frame = 2

Query:  989 KKTLARLVFKDF 1024
            +K+LARL+F DF
Sbjct:  309 QKSLARLMFNDF 320          

BLAST of DY258096 vs. ExPASy Swiss-Prot
Match: HMCS2_MOUSE (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Mus musculus GN=Hmgcs2 PE=1 SV=2)

HSP 1 Score: 301.982 bits (772), Expect = 1.381e-81
Identity = 148/263 (56.27%), Postives = 187/263 (71.10%), Query Frame = 1

Query:  220 TMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALDTCY----KCLCNKYQETGRETNFSFQRLINFWSIPPYNRLGQKN 996
            T  K+VGILA+++YFP   V Q  LE  +    GKYT+GLGQ  M FCS  ED+ S+ LT V  L+E+ K+    +GRLEVG+ET+IDKSK++KT LM++F+  GNTDIEG+D+TNACYGGTA+LFN  NW+ESS WDGRY LVVC D AVY  G ARPTGGA AV ML+GP AP+  E  LRG+HM +AYDFYKPNLASEYP+VDGKLS  CYL ALD CY    K + N++++ G    F+   +       P+ ++ QK+
Sbjct:   49 TWPKDVGILALEVYFPAQYVDQTDLEKFNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERTKLPWDAVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSYWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLVLEQGLRGTHMENAYDFYKPNLASEYPLVDGKLSIQCYLRALDRCYAAYRKKIQNQWKQAGNNQPFTLDDVQYMIFHTPFCKMVQKS 311          

HSP 2 Score: 21.1718 bits (43), Expect = 1.381e-81
Identity = 8/12 (66.67%), Postives = 11/12 (91.67%), Query Frame = 2

Query:  989 KKTLARLVFKDF 1024
            +K+LARL+F DF
Sbjct:  309 QKSLARLMFNDF 320